(Q38024276)

27 August 2017

Adult neurogenesis in Parkinson's disease (English)

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27 August 2017

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3

Jürgen Winkler

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27 August 2017

Franz Marxreiter

1

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PubMed ID

22766974

27 August 2017

Martin Regensburger

series ordinal

2

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27 August 2017

6 July 2012

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Cellular and Molecular Life Sciences

27 August 2017

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27 August 2017

70

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27 August 2017

459-473

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27 August 2017

3

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https://scigraph.springernature.com/pub.10.1007/s00018-012-1062-x

27 August 2017

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cites work

Spatial learning is unimpaired in mice containing a deletion of the alpha-synuclein locus.

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12 December 2020

Ectopic expression of α-synuclein affects the migration of neural stem cells in mouse subventricular zone

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12 December 2020

Genetic deletion of a neural cell adhesion molecule variant (N-CAM-180) produces distinct defects in the central nervous system

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12 December 2020

In situ detection of apoptotic nuclei in the substantia nigra compacta of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated mice using terminal deoxynucleotidyl transferase labelling and acridine orange staining

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12 December 2020

Synapse formation on adult-born hippocampal neurons

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12 December 2020

Temporal and spacial relationships between PSA-NCAM-expressing, newly generated granule cells, and radial glia-like cells in the adult dentate gyrus.

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12 December 2020

α-Synuclein occurs physiologically as a helically folded tetramer that resists aggregation

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12 December 2020

Reduced neurogenesis and pre-synaptic dysfunction in the olfactory bulb of a rat model of depression.

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12 December 2020

Medial septal lesions mimic effects of both selective dorsal and ventral hippocampal lesions.

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12 December 2020

Neurogenesis in substantia nigra of parkinsonian brains?

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12 December 2020

Epidermal growth factor and fibroblast growth factor-2 have different effects on neural progenitors in the adult rat brain

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12 December 2020

Cognitive decline correlates with neuropathological stage in Parkinson's disease

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12 December 2020

Mechanisms and functional implications of adult neurogenesis

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12 December 2020

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

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12 December 2020

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

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12 December 2020

Adult treatment with haloperidol increases dentate granule cell proliferation in the gerbil hippocampus.

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12 December 2020

Destruction of dopaminergic neurons in the midbrain by 6-hydroxydopamine decreases hippocampal cell proliferation in rats: reversal by fluoxetine

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12 December 2020

Neurogenesis in olfactory bulb identified by retroviral labeling in normal and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated adult mice

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12 December 2020

Caspase inhibition decreases cell death in regions of adult neurogenesis.

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12 December 2020

In vivo demonstration that alpha-synuclein oligomers are toxic

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12 December 2020

The dopaminergic mesencephalic projections to the hippocampal formation in the rat.

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12 December 2020

Experience dictates stem cell fate in the adult hippocampus

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12 December 2020

Odor deprivation leads to reduced neurogenesis and reduced neuronal survival in the olfactory bulb of the adult mouse

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12 December 2020

Glutathione peroxidase, glial cells and Parkinson's disease.

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12 December 2020

Learning and survival of newly generated neurons: when time matters.

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12 December 2020

Proliferation of neural precursors in the subventricular zone after chemical lesions of the nigrostriatal pathway in rat brain.

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12 December 2020

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

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12 December 2020

Running enhances neurogenesis, learning, and long-term potentiation in mice

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12 December 2020

Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus

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12 December 2020

Transient expression of doublecortin during adult neurogenesis

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12 December 2020

Dorsal striatal D2-like receptor availability covaries with sensitivity to positive reinforcement during discrimination learning

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12 December 2020

Striatal deafferentation increases dopaminergic neurogenesis in the adult olfactory bulb

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12 December 2020

Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation

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12 December 2020

Nonmotor symptoms as presenting complaints in Parkinson's disease: a clinicopathological study

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12 December 2020

Parkinson's disease: a rethink of rodent models.

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12 December 2020

The adult substantia nigra contains progenitor cells with neurogenic potential.

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12 December 2020

Transient elevation of adult hippocampal neurogenesis after dopamine depletion

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12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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12 December 2020

Odor perception and olfactory bulb plasticity in adult mammals

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12 December 2020

Genetic animal models of Parkinson's disease

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12 December 2020

Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters

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12 December 2020

Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice

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12 December 2020

Dopaminergic substantia nigra neurons project topographically organized to the subventricular zone and stimulate precursor cell proliferation in aged primates.

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12 December 2020

Cell survival and clinical outcome following intrastriatal transplantation in Parkinson disease

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12 December 2020

Alpha-synuclein cooperates with CSPalpha in preventing neurodegeneration

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12 December 2020

Coexistence of GABA and glutamate in mossy fiber terminals of the primate hippocampus: An ultrastructural study

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12 December 2020

The proliferative capacity of the subventricular zone is maintained in the parkinsonian brain

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12 December 2020

A possible role for dopamine D3 receptor stimulation in the induction of neurogenesis in the adult rat substantia nigra

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12 December 2020

Brain inflammation and adult neurogenesis: the dual role of microglia

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12 December 2020

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12 December 2020

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

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12 December 2020

Mild cognitive impairment in Parkinson disease: a multicenter pooled analysis.

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12 December 2020

Possibility for neurogenesis in substantia nigra of parkinsonian brain

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12 December 2020

Preferential incorporation of adult-generated granule cells into spatial memory networks in the dentate gyrus.

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12 December 2020

Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation

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12 December 2020

Enriched environment induces cellular plasticity in the adult substantia nigra and improves motor behavior function in the 6-OHDA rat model of Parkinson's disease

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12 December 2020

Behavioral phenotyping of the MPTP mouse model of Parkinson's disease

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12 December 2020

Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.

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12 December 2020

Subventricular zone astrocytes are neural stem cells in the adult mammalian brain

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12 December 2020

Dopamine D3 receptor stimulation promotes the proliferation of cells derived from the post-natal subventricular zone

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12 December 2020

Glial reactions in Parkinson's disease

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12 December 2020

A review of systems and networks of the limbic forebrain/limbic midbrain

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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12 December 2020

Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice

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12 December 2020

Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

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12 December 2020

Signaling in adult neurogenesis

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12 December 2020

Adult neurogenesis promotes synaptic plasticity in the olfactory bulb.

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12 December 2020

A functional role for adult hippocampal neurogenesis in spatial pattern separation

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12 December 2020

Adult neurogenesis and neurite outgrowth are impaired in LRRK2 G2019S mice

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12 December 2020

Human Neuroblasts Migrate to the Olfactory Bulb via a Lateral Ventricular Extension

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12 December 2020

Adult hippocampal neurogenesis is involved in anxiety-related behaviors.

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12 December 2020

Platelet-derived growth factor (PDGF-BB) and brain-derived neurotrophic factor (BDNF) induce striatal neurogenesis in adult rats with 6-hydroxydopamine lesions

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12 December 2020

Dopaminergic lesion enhances growth factor-induced striatal neuroblast migration.

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12 December 2020

A critical period for activity-dependent synaptic development during olfactory bulb adult neurogenesis

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12 December 2020

Signaling in adult neurogenesis.

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12 December 2020

Lewy body-like pathology in long-term embryonic nigral transplants in Parkinson's disease

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12 December 2020

Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain

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12 December 2020

Cellular and behavioral effects of cranial irradiation of the subventricular zone in adult mice.

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12 December 2020

Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors

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12 December 2020

Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine

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12 December 2020

Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates.

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12 December 2020

Different species of alpha-synuclein oligomers induce calcium influx and seeding.

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12 December 2020

Dopaminergic modulation of cortical inputs during maturation of adult-born dentate granule cells

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12 December 2020

Dopamine depletion impairs precursor cell proliferation in Parkinson disease.

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12 December 2020

Changes in adult olfactory bulb neurogenesis in mice expressing the A30P mutant form of alpha-synuclein

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12 December 2020

Olfactory discrimination learning increases the survival of adult-born neurons in the olfactory bulb.

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12 December 2020

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

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12 December 2020

Inclusion formation and neuronal cell death through neuron-to-neuron transmission of alpha-synuclein

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12 December 2020

Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice.

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12 December 2020

Increased progenitor cell proliferation and astrogenesis in the partial progressive 6-hydroxydopamine model of Parkinson's disease.

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12 December 2020

Differential response of ventral midbrain and striatal progenitor cells to lesions of the nigrostriatal dopaminergic projection

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12 December 2020

Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders.

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12 December 2020

Antidepressants increase neural progenitor cells in the human hippocampus

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12 December 2020

Reduced olfactory bulb volume and olfactory sensitivity in patients with acute major depression

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12 December 2020

Long-distance neuronal migration in the adult mammalian brain

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12 December 2020

Long-term stimulation of neural progenitor cell migration after cortical ischemia in mice.

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12 December 2020

LRK-1, a C. elegans PARK8-related kinase, regulates axonal-dendritic polarity of SV proteins.

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12 December 2020

Decreased olfactory bulb volume in idiopathic Parkinson's disease detected by 3.0-tesla magnetic resonance imaging.

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12 December 2020

Direct transfer of alpha-synuclein from neuron to astroglia causes inflammatory responses in synucleinopathies

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12 December 2020

Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice

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12 December 2020

Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

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12 December 2020

A niche for adult neural stem cells

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12 December 2020

Long-term survival and cell death of newly generated neurons in the adult rat olfactory bulb

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12 December 2020

FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain

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12 December 2020

Neuronal replacement from endogenous precursors in the adult brain after stroke

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12 December 2020

D3 dopamine receptors do not regulate neurogenesis in the subventricular zone of adult mice

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12 December 2020

Premotor Parkinson disease

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12 December 2020

Down-regulation of alpha-synuclein expression can rescue dopaminergic cells from cell death in the substantia nigra of Parkinson's disease rat model

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12 December 2020

No evidence for new dopaminergic neurons in the adult mammalian substantia nigra

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12 December 2020

Autoradiographic and histological studies of postnatal neurogenesis. IV. Cell proliferation and migration in the anterior forebrain, with special reference to persisting neurogenesis in the olfactory bulb

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12 December 2020

Neuropathology of sporadic Parkinson's disease: evaluation and changes of concepts

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12 December 2020

Astroglia induce neurogenesis from adult neural stem cells

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12 December 2020

Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus

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12 December 2020

Olfactory neuron-specific expression of A30P α-synuclein exacerbates dopamine deficiency and hyperactivity in a novel conditional model of early Parkinson's disease stages

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12 December 2020

Mice lacking alpha-synuclein have an attenuated loss of striatal dopamine following prolonged chronic MPTP administration

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12 December 2020

Decreased hippocampal neurogenesis following olfactory bulbectomy is reversed by repeated citalopram administration.

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12 December 2020

Midbrain dopamine neurons associated with reward processing innervate the neurogenic subventricular zone

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12 December 2020

Influences of dopaminergic lesion on epidermal growth factor-ErbB signals in Parkinson's disease and its model: neurotrophic implication in nigrostriatal neurons

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12 December 2020

Evidence for neurogenesis in the adult mammalian substantia nigra

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12 December 2020

Radiation-induced cognitive impairments are associated with changes in indicators of hippocampal neurogenesis

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12 December 2020

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

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12 December 2020

Dopaminergic nigrostriatal projections regulate neural precursor proliferation in the adult mouse subventricular zone

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12 December 2020

αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction

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12 December 2020

Mutant alpha-synuclein exacerbates age-related decrease of neurogenesis

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12 December 2020

Is adult neurogenesis essential for olfaction?

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12 December 2020

Dopamine receptor activation promotes adult neurogenesis in an acute Parkinson model

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12 December 2020

In vivo RNAi-mediated alpha-synuclein silencing induces nigrostriatal degeneration

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12 December 2020

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

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12 December 2020

Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy

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12 December 2020

Deletion of the alpha-synuclein locus in a subpopulation of C57BL/6J inbred mice

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12 December 2020

A 100% increase of dopaminergic cells in the olfactory bulb may explain hyposmia in Parkinson's disease

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12 December 2020

Neurogenesis in adult subventricular zone.

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12 December 2020

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

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12 December 2020

Functional neurogenesis in the adult hippocampus

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12 December 2020

Control of microglial neurotoxicity by the fractalkine receptor

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12 December 2020

Antidepressants alter cell proliferation in the adult brain in vivo and in neural cultures in vitro.

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12 December 2020

Alpha-synuclein and its disease-causing mutants induce ICAM-1 and IL-6 in human astrocytes and astrocytoma cells

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12 December 2020

Corridors of migrating neurons in the human brain and their decline during infancy.

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12 December 2020

α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies

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12 December 2020

CNS stem cells express a new class of intermediate filament protein

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12 December 2020

Depletion in serotonin decreases neurogenesis in the dentate gyrus and the subventricular zone of adult rats.

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12 December 2020

Genetics of Parkinson disease: paradigm shifts and future prospects.

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12 December 2020

Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology

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12 December 2020

Persistent production of neurons from adult brain stem cells during recovery after stroke.

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12 December 2020

Chain migration of neuronal precursors.

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12 December 2020

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12 December 2020

Directing astroglia from the cerebral cortex into subtype specific functional neurons

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12 December 2020

Dopamine specifically inhibits forebrain neural stem cell proliferation, suggesting a novel effect of antipsychotic drugs.

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12 December 2020

Staging of brain pathology related to sporadic Parkinson's disease

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12 December 2020

Neurogenesis in the adult human hippocampus

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12 December 2020

GFAP-expressing progenitors are the principal source of constitutive neurogenesis in adult mouse forebrain

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12 December 2020

Learning-dependent neurogenesis in the olfactory bulb determines long-term olfactory memory.

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12 December 2020

In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus

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12 December 2020

Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

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12 December 2020

Disruption of Adult Neurogenesis in the Olfactory Bulb Affects Social Interaction but not Maternal Behavior

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12 December 2020

Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus

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12 December 2020

Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging.

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12 December 2020

Dopamine D3 receptor agonist delivery to a model of Parkinson's disease restores the nigrostriatal pathway and improves locomotor behavior.

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12 December 2020

Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.

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12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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12 December 2020

Rat forebrain neurogenesis and striatal neuron replacement after focal stroke

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12 December 2020

Role of alpha-synuclein in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

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12 December 2020

Dopamine-induced proliferation of adult neural precursor cells in the mammalian subventricular zone is mediated through EGF.

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12 December 2020

Functional integration of dopaminergic neurons directly converted from mouse fibroblasts

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12 December 2020

Parkinson's disease risk score: moving to a premotor diagnosis

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12 December 2020

Human Wild-Type α-Synuclein Impairs Neurogenesis

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12 December 2020

Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus

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12 December 2020

Ablation of mouse adult neurogenesis alters olfactory bulb structure and olfactory fear conditioning

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12 December 2020

Fractalkine and CX 3 CR1 regulate hippocampal neurogenesis in adult and aged rats

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12 December 2020

Control of memory formation through regulated expression of a CaMKII transgene

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12 December 2020

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

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12 December 2020

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

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12 December 2020

A critical period for enhanced synaptic plasticity in newly generated neurons of the adult brain

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12 December 2020

10.1007/S00018-012-1062-X

Identifiers

DOI

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27 August 2017

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PubMed ID

22766974