(Q38027859)

27 August 2017

title

Formulation strategies for sustained release of proteins (English)

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27 August 2017

Andrew L Lewis

1

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27 August 2017

Lisbeth Illum

series ordinal

2

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27 August 2017

publication date

1 September 2010

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27 August 2017

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27 August 2017

volume

1

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27 August 2017

issue

3

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27 August 2017

page(s)

457-479

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Patient-friendly bioerodible drug delivery systems

27 August 2017

cites work

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Photographic estimation of the duration of high dose intravitreal triamcinolone in the vitrectomised eye

21 January 2018

1 reference

Comparative pharmacokinetics and pharmacodynamics of a new sustained-release growth hormone (GH), LB03002, versus daily GH in adults with GH deficiency.

21 January 2018

1 reference

SEMIPERMEABLE MICROCAPSULES

21 January 2018

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Polymers for the sustained release of proteins and other macromolecules

21 January 2018

1 reference

Biodegradation and biocompatibility of PLA and PLGA microspheres

21 January 2018

1 reference

Plasticizing effect of water on poly(lactide-co-glycolide).

21 January 2018

1 reference

An investigation into the effects of residual water on the glass transition temperature of polylactide microspheres using modulated temperature DSC.

21 January 2018

1 reference

Characterization of the initial burst release of a model peptide from poly(D,L-lactide-co-glycolide) microspheres

21 January 2018

1 reference

Visual evidence of acidic environment within degrading poly(lactic-co-glycolic acid) (PLGA) microspheres

21 January 2018

1 reference

Acidic microclimate pH distribution in PLGA microspheres monitored by confocal laser scanning microscopy

21 January 2018

1 reference

Mapping neutral microclimate pH in PLGA microspheres

21 January 2018

1 reference

Prediction of microclimate pH in poly(lactic-co-glycolic acid) films

21 January 2018

1 reference

PLGA-based drug delivery systems: importance of the type of drug and device geometry

21 January 2018

1 reference

Influence of particle size and dissolution conditions on the degradation properties of polylactide-co-glycolide particles

21 January 2018

1 reference

A subcutaneous delivery system for the extended release of leuprolide acetate for the treatment of prostate cancer

21 January 2018

1 reference

Injectable in situ forming depot systems: PEG-DAE as novel solvent for improved PLGA storage stability

21 January 2018

1 reference

Poly(ethyleneglycol) 500 dimethylether as novel solvent for injectable in situ forming depots

21 January 2018

1 reference

Changes in morphology of in situ forming PLGA implant prepared by different polymer molecular weight and its effect on release behavior

21 January 2018

1 reference

Influence of the poly(lactide-co-glycolide) type on the leuprolide release from in situ forming microparticle systems

21 January 2018

1 reference

In situ forming microparticle system for controlled delivery of leuprolide acetate: influence of the formulation and processing parameters

21 January 2018

1 reference

A novel in situ forming drug delivery system for controlled parenteral drug delivery

21 January 2018

1 reference

Sustained delivery of human growth hormone from a novel gel system: SABER.

21 January 2018

1 reference

Injectable controlled release formulations incorporating protein crystals

21 January 2018

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Sustained release of human growth hormone from in situ forming hydrogels using self-assembly of fluoroalkyl-ended poly(ethylene glycol).

21 January 2018

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Systemic allergic dermatitis caused by the solvent of Eligard

21 January 2018

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Biodegradable block copolymers as injectable drug-delivery systems

21 January 2018

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Biodegradable block copolymers for delivery of proteins and water-insoluble drugs

21 January 2018

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Controlled release of growth hormone from thermosensitive triblock copolymer systems: In vitro and in vivo evaluation

21 January 2018

1 reference

Rheological characterization of Poloxamer 407 lidocaine hydrochloride gels

21 January 2018

1 reference

Sustained release of lidocaine from Poloxamer 407 gels

21 January 2018

1 reference

Development and in-vitro evaluation of sustained release poloxamer 407 (P407) gel formulations of ceftiofur

21 January 2018

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Protein instability in poly(lactic-co-glycolic acid) microparticles.

21 January 2018

1 reference

Biodegradable thermogelling hydrogel of P(CL-GL)-PEG-P(CL-GL) triblock copolymer: degradation and drug release behavior.

21 January 2018

1 reference

The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices

21 January 2018

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Microencapsulation by solvent extraction/evaporation: reviewing the state of the art of microsphere preparation process technology

21 January 2018

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Preparation of microspheres by the solvent evaporation technique

21 January 2018

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Non-native intermediate conformational states of human growth hormone in the presence of organic solvents

21 January 2018

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Stable formulations of recombinant human growth hormone and interferon-gamma for microencapsulation in biodegradable microspheres

21 January 2018

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Encapsulation-induced aggregation and loss in activity of gamma-chymotrypsin and their prevention

21 January 2018

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Effect of salts on lysozyme stability at the water–oil interface and upon encapsulation in poly(lactic‐co‐glycolic) acid microspheres

21 January 2018

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Improved activity and stability of lysozyme at the water/CH2Cl2 interface: enzyme unfolding and aggregation and its prevention by polyols

21 January 2018

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Reduction of structural perturbations in bovine serum albumin by non-aqueous microencapsulation

21 January 2018

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Preservation of lysozyme structure and function upon encapsulation and release from poly(lactic-co-glycolic) acid microspheres prepared by the water-in-oil-in-water method

21 January 2018

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The stability of recombinant human growth hormone in poly(lactic-co-glycolic acid) (PLGA) microspheres

21 January 2018

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Recombinant human growth hormone poly(lactic-co-glycolic acid) microsphere formulation development

21 January 2018

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Development of a sustained-release recombinant human growth hormone formulation.

21 January 2018

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Effect of cyclodextrins on alpha-chymotrypsin stability and loading in PLGA microspheres upon S/O/W encapsulation

21 January 2018

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Feeding liquid, non-ionic surfactant and cyclodextrin affect the properties of insulin-loaded poly(lactide-co-glycolide) microspheres prepared by spray-drying

21 January 2018

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How cyclodextrin incorporation affects the properties of protein-loaded PLGA-based microspheres: the case of insulin/hydroxypropyl-beta-cyclodextrin system.

21 January 2018

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Zero-order release of lysozyme from poly(ethylene glycol)/poly(butylene terephthalate) matrices.

21 January 2018

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Stability aspects of salmon calcitonin entrapped in poly(ether-ester) sustained release systems.

21 January 2018

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Non-aqueous encapsulation of excipient-stabilized spray-freeze dried BSA into poly(lactide-co-glycolide) microspheres results in release of native protein.

21 January 2018

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Relationship between encapsulated drug particle size and initial release of recombinant human growth hormone from biodegradable microspheres

21 January 2018

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Sustained release of human growth hormone from microcapsules prepared by a solvent evaporation technique

21 January 2018

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Encapsulation of bovine serum albumin in poly(lactide-co-glycolide) microspheres by the solid-in-oil-in-water technique

21 January 2018

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Stabilization and encapsulation of human immunoglobulin G into biodegradable microspheres

21 January 2018

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Stabilization of proteins encapsulated in injectable poly (lactide- co-glycolide)

21 January 2018

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Comparison of the effects of Mg(OH)2 and sucrose on the stability of bovine serum albumin encapsulated in injectable poly(D,L-lactide-co-glycolide) implants

21 January 2018

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Poly(ethylene glycol) as stabilizer and emulsifying agent: a novel stabilization approach preventing aggregation and inactivation of proteins upon encapsulation in bioerodible polyester microspheres

21 January 2018

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Improved alpha-chymotrypsin stability upon encapsulation in PLGA microspheres by solvent replacement

21 January 2018

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Protein encapsulation into biodegradable microspheres by a novel S/O/W emulsion method using poly(ethylene glycol) as a protein micronization adjuvant

21 January 2018

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Applicability of various amphiphilic polymers to the modification of protein release kinetics from biodegradable reservoir-type microspheres

21 January 2018

1 reference

A novel sustained-release formulation of insulin with dramatic reduction in initial rapid release

21 January 2018

1 reference

Insulin-loaded biodegradable PLGA microcapsules: initial burst release controlled by hydrophilic additives

21 January 2018

1 reference

Optimum formulation for sustained-release insulin

21 January 2018

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A novel insulin formulation can keep providing steady levels of insulin for much longer periods in-vivo

21 January 2018

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Development and scale-up of a microsphere protein delivery system

21 January 2018

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A month-long effect from a single injection of microencapsulated human growth hormone

21 January 2018

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The stabilization and encapsulation of human growth hormone into biodegradable microspheres

21 January 2018

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Pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (nutropin depot) in GH-deficient children

21 January 2018

1 reference

Plasticization and spraying of poly (DL-lactic acid) using supercritical carbon dioxide: control of particle size

21 January 2018

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Sustained release hGH microsphere formulation produced by a novel supercritical fluid technology: in vivo studies.

21 January 2018

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A new sustained-release preparation of human growth hormone and its pharmacokinetic, pharmacodynamic and safety profile.

21 January 2018

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Effect of excipients on the encapsulation efficiency and release of human growth hormone from dextran microspheres

21 January 2018

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Preclinical and clinical in vitro in vivo correlation of an hGH dextran microsphere formulation

21 January 2018

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Preparation and characterization of a composite PLGA and poly(acryloyl hydroxyethyl starch) microsphere system for protein delivery

21 January 2018

1 reference

Preparation and characterization of poly(D,L-lactide-co-glycolide) microspheres for controlled release of human growth hormone

21 January 2018

1 reference

Preparation and in vitro/in vivo evaluation of insulin-loaded poly(acryloyl-hydroxyethyl starch)-PLGA composite microspheres

21 January 2018

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Novel composite microparticles for protein stabilization and delivery

21 January 2018

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Comparative study on sustained release of human growth hormone from semi-crystalline poly(L-lactic acid) and amorphous poly(D,L-lactic-co-glycolic acid) microspheres: morphological effect on protein release

21 January 2018

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Biodegradable polymeric microspheres with "open/closed" pores for sustained release of human growth hormone

21 January 2018

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Fabrication of covered porous PLGA microspheres using hydrogen peroxide for controlled drug delivery and regenerative medicine

21 January 2018

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Peptide acylation by poly(alpha-hydroxy esters).

21 January 2018

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Identification of chemically modified peptide from poly(D,L-lactide-co-glycolide) microspheres under in vitro release conditions

21 January 2018

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Impurity formation studies with peptide-loaded polymeric microspheres Part I. In vivo evaluation

21 January 2018

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Impurity formation studies with peptide-loaded polymeric microspheres Part II. In vitro evaluation

21 January 2018

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Stability of insulin during the erosion of poly(lactic acid) and poly(lactic-co-glycolic acid) microspheres

21 January 2018

1 reference

Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres

21 January 2018

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Adsorption of salmon calcitonin to PLGA microspheres.

21 January 2018

1 reference

Assessment of protein release kinetics, stability and protein polymer interaction of lysozyme encapsulated poly(D,L-lactide-co-glycolide) microspheres

21 January 2018

1 reference

Review on Medusa:a polymer-based sustained release technology for protein and peptide drugs

21 January 2018

1 reference

Injectable microparticle-gel system for prolonged and localized lidocaine release. I. In vitro characterization

21 January 2018

1 reference

Injectable microparticle-gel system for prolonged and localized lidocaine release. II. In vivo anesthetic effects

21 January 2018

1 reference

THE USE OF SILICONE RUBBER AS A CARRIER FOR PROLONGED DRUG THERAPY

21 January 2018

1 reference

Pharmacokinetic and pharmacodynamic profile of a new sustained-release GH formulation, LB03002, in children with GH deficiency

21 January 2018

1 reference

Semipermeable Microcapsules containing Catalase for Enzyme Replacement in Acatalasaemic Mice

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/TDE.10.17

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27 August 2017

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