(Q38035206)

27 August 2017

title

CD133 as a biomarker for putative cancer stem cells in solid tumours: limitations, problems and challenges (English)

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27 August 2017

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neoplastic stem cells

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7

Leoni A Kunz-Schughart

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27 August 2017

author name string

Philipp Grosse-Gehling

1

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27 August 2017

Christine A Fargeas

2

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27 August 2017

Claudia Dittfeld

3

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27 August 2017

Yvette Garbe

4

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27 August 2017

Malcolm R Alison

5

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27 August 2017

Denis Corbeil

6

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27 August 2017

publication date

20 November 2012

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27 August 2017

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27 August 2017

volume

229

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27 August 2017

issue

3

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27 August 2017

page(s)

355-378

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Characterization of prominin-2, a new member of the prominin family of pentaspan membrane glycoproteins

27 August 2017

cites work

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The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions

21 January 2018

1 reference

Prominin-1/CD133, a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer.

21 January 2018

1 reference

A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration

21 January 2018

1 reference

Prominin: a story of cholesterol, plasma membrane protrusions and human pathology.

21 January 2018

1 reference

AC133 antigen, CD133, prominin-1, prominin-2, etc.: prominin family gene products in need of a rational nomenclature.

21 January 2018

1 reference

Identification of novel Prominin-1/CD133 splice variants with alternative C-termini and their expression in epididymis and testis

21 January 2018

1 reference

AC133-2, a novel isoform of human AC133 stem cell antigen

21 January 2018

1 reference

Nomenclature of prominin-1 (CD133) splice variants - an update.

21 January 2018

1 reference

The stem cell marker CD133 (prominin-1) is phosphorylated on cytoplasmic tyrosine-828 and tyrosine-852 by Src and Fyn tyrosine kinases

21 January 2018

1 reference

Expression of distinct splice variants of the stem cell marker prominin-1 (CD133) in glial cells

21 January 2018

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Promoter hypomethylation regulates CD133 expression in human gliomas

21 January 2018

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The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation

21 January 2018

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Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks

21 January 2018

1 reference

Epigenetics and gene expression

21 January 2018

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The role of DNA methylation in cancer genetic and epigenetics

21 January 2018

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Epigenetic changes in cancer

21 January 2018

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Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors

21 January 2018

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Epigenetic regulation of CD133 and tumorigenicity of CD133+ ovarian cancer cells

21 January 2018

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Promoter hypermethylation and loss of CD133 gene expression in colorectal cancers

21 January 2018

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Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells

21 January 2018

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Epigenetics and cancer treatment

21 January 2018

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Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells

21 January 2018

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Histone deacetylase inhibitors: Potential in cancer therapy

21 January 2018

1 reference

Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and in glioma stem-like cells.

21 January 2018

1 reference

Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells

21 January 2018

1 reference

Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1

21 January 2018

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Retention of prominin in microvilli reveals distinct cholesterol-based lipid micro-domains in the apical plasma membrane.

21 January 2018

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Release of extracellular membrane vesicles from microvilli of epithelial cells is enhanced by depleting membrane cholesterol.

21 January 2018

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GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells.

21 January 2018

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The first extracellular domain of the tumour stem cell marker CD133 contains an antigenic ganglioside-binding motif

21 January 2018

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CD133 and membrane microdomains: old facets for future hypotheses.

21 January 2018

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Loss of the cholesterol-binding protein prominin-1/CD133 causes disk dysmorphogenesis and photoreceptor degeneration

21 January 2018

1 reference

Focus on molecules: prominin-1 (CD133).

21 January 2018

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Release of extracellular membrane particles carrying the stem cell marker prominin-1 (CD133) from neural progenitors and other epithelial cells

21 January 2018

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New insights into the cell biology of hematopoietic progenitors by studying prominin-1 (CD133).

21 January 2018

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Haematopoietic stem cell differentiation promotes the release of prominin-1/CD133-containing membrane vesicles--a role of the endocytic-exocytic pathway

21 January 2018

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Membrane vesicles as conveyors of immune responses

21 January 2018

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CD133 expression is an independent prognostic marker for low survival in colorectal cancer

21 January 2018

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Identification of CD133-positive radioresistant cells in atypical teratoid/rhabdoid tumor

21 January 2018

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CD133-positive cells are resistant to TRAIL due to up-regulation of FLIP.

21 January 2018

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Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

21 January 2018

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Pancreatic Cancer Cells Resistant to Chemoradiotherapy Rich in “Stem-Cell-Like” Tumor Cells

21 January 2018

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The stem cell marker prominin-1/CD133 on membrane particles in human cerebrospinal fluid offers novel approaches for studying central nervous system disease.

21 January 2018

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N-linked oligosaccharides as outfitters for glycoprotein folding, form and function

21 January 2018

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Complex genetic regulation of protein glycosylation

21 January 2018

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Importance of glycosidases in mammalian glycoprotein biosynthesis

21 January 2018

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CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope

21 January 2018

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Alpha2,3-Sialylation regulates the stability of stem cell marker CD133.

21 January 2018

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Polysialic acids: potential in improving the stability and pharmacokinetics of proteins and other therapeutics

21 January 2018

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Improving the therapeutic efficacy of peptides and proteins: a role for polysialic acids

21 January 2018

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Sialidase and malignancy: a minireview

21 January 2018

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Glycan changes: cancer metastasis and anti-cancer vaccines

21 January 2018

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N-glycan structures and associated gene expression reflect the characteristic N-glycosylation pattern of human hematopoietic stem and progenitor cells.

21 January 2018

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Glycosylation defining cancer malignancy: new wine in an old bottle

21 January 2018

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N-Glycans in cancer progression

21 January 2018

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Alterations in glycosylation as biomarkers for cancer detection

21 January 2018

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The utility and limitations of glycosylated human CD133 epitopes in defining cancer stem cells

21 January 2018

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The stem cell marker CD133 (Prominin-1) is expressed in various human glandular epithelia.

21 January 2018

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Expression of the "stem cell marker" CD133 in pancreas and pancreatic ductal adenocarcinomas

21 January 2018

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Inconsistent immunohistochemical expression patterns of four different CD133 antibody clones in glioblastoma

21 January 2018

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Monoclonal antibody CD133-2 (AC141) against hematopoietic stem cell antigen CD133 shows crossreactivity with cytokeratin 18.

21 January 2018

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The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cells

21 January 2018

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Expression and regulation of AC133 and CD133 in glioblastoma

21 January 2018

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Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult human pancreas.

21 January 2018

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Prominin-1 (CD133) is not restricted to stem cells located in the basal compartment of murine and human prostate.

21 January 2018

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Generation of a prostate from a single adult stem cell

21 January 2018

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Direct isolation of human central nervous system stem cells

21 January 2018

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CD133, a novel marker for human prostatic epithelial stem cells.

21 January 2018

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Human hepatic stem cells from fetal and postnatal donors

21 January 2018

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Isolation of renal progenitor cells from adult human kidney

21 January 2018

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CD133+ adult human retinal cells remain undifferentiated in Leukaemia Inhibitory Factor (LIF)

21 January 2018

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Phenotypes of stem cells from diverse origin

21 January 2018

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CD133(+) cells isolated from various sources and their role in future clinical perspectives

21 January 2018

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Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation

21 January 2018

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Mesenchymal stromal cells can be derived from bone marrow CD133+ cells: implications for therapy

21 January 2018

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Mobilization of very small embryonic-like stem cells in acute coronary syndromes and stroke

21 January 2018

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Hematopoietic colony-forming cells derived from human embryonic stem cells

21 January 2018

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Characterization and Differentiation of Human Embryonic Stem Cells

21 January 2018

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Generation of new human embryonic stem cell lines with diploid and triploid karyotypes

21 January 2018

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CD marker expression profiles of human embryonic stem cells and their neural derivatives, determined using flow-cytometric analysis, reveal a novel CD marker for exclusion of pluripotent stem cells.

21 January 2018

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Subpopulations of human embryonic stem cells with distinct tissue-specific fates can be selected from pluripotent cultures

21 January 2018

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Epigenetic landscaping during hESC differentiation to neural cells.

21 January 2018

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Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons

21 January 2018

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Human circulating AC133(+) stem cells restore dystrophin expression and ameliorate function in dystrophic skeletal muscle

21 January 2018

1 reference

Endothelial progenitor cells: identity defined?

21 January 2018

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Endothelial progenitor cells as a new agent contributing to vascular repair.

21 January 2018

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Stem cell concepts renew cancer research

21 January 2018

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

21 January 2018

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Stem cells and solid cancers

21 January 2018

1 reference

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

21 January 2018

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The cancer stem cell: premises, promises and challenges

21 January 2018

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Cancer stem cells: in the line of fire

21 January 2018

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The fuzzy math of solid tumor stem cells: a perspective.

21 January 2018

1 reference

The Effect of Lethally Irradiated Cells on the Transplantability of Murine Tumours

21 January 2018

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Efficient tumour formation by single human melanoma cells

21 January 2018

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Cancer stem cells and radiotherapy.

21 January 2018

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Cancer stem cells as a predictive factor in radiotherapy

21 January 2018

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Identification of human brain tumour initiating cells

21 January 2018

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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

21 January 2018

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Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas.

21 January 2018

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CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells

21 January 2018

1 reference

Characterization of a subpopulation of colon cancer cells with stem cell-like properties

21 January 2018

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Phenotypic characterization of human colorectal cancer stem cells

21 January 2018

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CD133 negative cancer stem cells in glioblastoma

21 January 2018

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Deadly teamwork: neural cancer stem cells and the tumor microenvironment

21 January 2018

1 reference

Glioma-initiating cells and molecular pathology: implications for therapy

21 January 2018

1 reference

Insight into the complex regulation of CD133 in glioma

21 January 2018

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Cells of origin in cancer

21 January 2018

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Identification and expansion of human colon-cancer-initiating cells

21 January 2018

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A human colon cancer cell capable of initiating tumour growth in immunodeficient mice

21 January 2018

1 reference

The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer

21 January 2018

1 reference

Cancer cells in epithelial-to-mesenchymal transition and tumor-propagating-cancer stem cells: distinct, overlapping or same populations

21 January 2018

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Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis

21 January 2018

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Symmetric division of cancer stem cells--a key mechanism in tumor growth that should be targeted in future therapeutic approaches

21 January 2018

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Genome and transcriptome profiles of CD133-positive colorectal cancer cells.

21 January 2018

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Colon cancer stem cells dictate tumor growth and resist cell death by production of interleukin-4.

21 January 2018

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

21 January 2018

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Colon cancer stem cells: promise of targeted therapy.

21 January 2018

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CD133 and nuclear beta-catenin: the marker combination to detect high risk cases of low stage colorectal cancer

21 January 2018

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Stem cell niche: structure and function

21 January 2018

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Out of Eden: stem cells and their niches

21 January 2018

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Attributes of adult stem cells

21 January 2018

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Asymmetric cell division: recent developments and their implications for tumour biology

21 January 2018

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Stem cells find their niche

21 January 2018

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Normal stem cells and cancer stem cells: the niche matters

21 January 2018

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Cancer stem cells and their niche

21 January 2018

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Location, location, location: the cancer stem cell niche

21 January 2018

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The cancer stem cell niche--there goes the neighborhood?

21 January 2018

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Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

21 January 2018

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Cancer stem cell niche: the place to be

21 January 2018

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CD133 as a marker for cancer stem cells: progresses and concerns

21 January 2018

1 reference

Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.

21 January 2018

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Transcriptional profiling of human cord blood CD133+ and cultured bone marrow mesenchymal stem cells in response to hypoxia

21 January 2018

1 reference

HIF induces human embryonic stem cell markers in cancer cells.

21 January 2018

1 reference

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.

21 January 2018

1 reference

Effects of hypoxia on expression of a panel of stem cell and chemoresistance markers in glioblastoma-derived spheroids

21 January 2018

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The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

21 January 2018

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Hypoxia inducible factors in cancer stem cells

21 January 2018

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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

21 January 2018

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Physiologic oxygen concentration enhances the stem-like properties of CD133+ human glioblastoma cells in vitro.

21 January 2018

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CD133 is a marker of bioenergetic stress in human glioma

21 January 2018

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Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia

21 January 2018

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Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1α-dependent manner in pancreatic cancer cells.

21 January 2018

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Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres

21 January 2018

1 reference

mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells

21 January 2018

1 reference

Hypoxia: importance in tumor biology, noninvasive measurement by imaging, and value of its measurement in the management of cancer therapy

21 January 2018

1 reference

A temporarily distinct subpopulation of slow-cycling melanoma cells is required for continuous tumor growth

21 January 2018

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The stem cell marker CD133 associates with enhanced colony formation and cell motility in colorectal cancer

21 January 2018

1 reference

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

21 January 2018

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Hypoxia-induced mixed-lineage leukemia 1 regulates glioma stem cell tumorigenic potential

21 January 2018

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Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

1 reference

CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway.

21 January 2018

1 reference

The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations

21 January 2018

1 reference

WNT-conditioned media differentially affect the proliferation and differentiation of cord blood-derived CD133+ cells in vitro

21 January 2018

1 reference

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

21 January 2018

1 reference

Crypt stem cells as the cells-of-origin of intestinal cancer

21 January 2018

1 reference

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

21 January 2018

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Neural stem cells and the origin of gliomas

21 January 2018

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The brain tumor microenvironment.

21 January 2018

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A perivascular niche for brain tumor stem cells

21 January 2018

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Integrin alpha 6 regulates glioblastoma stem cells

21 January 2018

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CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma.

21 January 2018

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

1 reference

Tumor stroma and regulation of cancer development

21 January 2018

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Prospectively isolated cancer-associated CD10(+) fibroblasts have stronger interactions with CD133(+) colon cancer cells than with CD133(-) cancer cells

21 January 2018

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CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells

21 January 2018

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Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1α/CXCR4 paracrine signaling

21 January 2018

1 reference

EMT: when epithelial cells decide to become mesenchymal-like cells

21 January 2018

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The basics of epithelial-mesenchymal transition

21 January 2018

1 reference

Cancer Stem Cells and Epithelial-to-Mesenchymal Transition (EMT)-Phenotypic Cells: Are They Cousins or Twins?

21 January 2018

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Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?

21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

1 reference

Establishment of a highly migratory subclone reveals that CD133 contributes to migration and invasion through epithelial-mesenchymal transition in pancreatic cancer.

21 January 2018

1 reference

CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer

21 January 2018

1 reference

Tenascin C induces epithelial-mesenchymal transition-like change accompanied by SRC activation and focal adhesion kinase phosphorylation in human breast cancer cells

21 January 2018

1 reference

The percentage of CD133+ cells in human colorectal cancer cell lines is influenced by Mycoplasma hyorhinis infection

21 January 2018

1 reference

Phenotypic heterogeneity among tumorigenic melanoma cells from patients that is reversible and not hierarchically organized

21 January 2018

1 reference

Cancer stem cells versus phenotype-switching in melanoma

21 January 2018

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Progress in understanding melanoma propagation

21 January 2018

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How powerful is CD133 as a cancer stem cell marker in brain tumors?

21 January 2018

1 reference

Stem cell marker CD133 affects clinical outcome in glioma patients.

21 January 2018

1 reference

Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients.

21 January 2018

1 reference

Cancer stem cell analysis and clinical outcome in patients with glioblastoma multiforme.

21 January 2018

1 reference

Expression and clinical significance of stem cell marker CD133 in human neuroblastoma.

21 January 2018

1 reference

Expression of stem cell markers in human astrocytomas of different WHO grades

21 January 2018

1 reference

Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma

21 January 2018

1 reference

Surrogate markers predict angiogenic potential and survival in patients with glioblastoma multiforme

21 January 2018

1 reference

Clinical significance of circulating tumor cells, including cancer stem-like cells, in peripheral blood for recurrence and prognosis in patients with Dukes' stage B and C colorectal cancer.

21 January 2018

1 reference

Prognostic value of putative circulating cancer stem cells in patients undergoing hepatic resection for colorectal liver metastasis.

21 January 2018

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21 January 2018

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A multigene predictor of outcome in glioblastoma.

21 January 2018

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21 January 2018

1 reference

CD133 expression and cancer stem cells predict prognosis in high-grade oligodendroglial tumors.

21 January 2018

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High levels of PROM1 (CD133) transcript are a potential predictor of poor prognosis in medulloblastoma

21 January 2018

1 reference

Prognostic impact of CD133 mRNA expression in 48 glioblastoma patients treated with concomitant radiochemotherapy: a prospective patient cohort at a single institution.

21 January 2018

1 reference

Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy

21 January 2018

1 reference

CD133 mRNA expression and microsatellite instability in colorectal carcinoma.

21 January 2018

1 reference

Predictive value of cancer stem-like cells and cancer-associated genetic markers for peritoneal recurrence of colorectal cancer in patients after curative surgery

21 January 2018

1 reference

Pharmacogenetic profiling of CD133 is associated with response rate (RR) and progression-free survival (PFS) in patients with metastatic colorectal cancer (mCRC), treated with bevacizumab-based chemotherapy

21 January 2018

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CD133 expression predicts for non-response to chemotherapy in colorectal cancer

21 January 2018

1 reference

Immunohistochemical features of CD133 expression: association with resistance to chemoradiotherapy in rectal cancer

21 January 2018

1 reference

Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer

21 January 2018

1 reference

Exploring the role of cancer stem cells in radioresistance

21 January 2018

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γ-secretase inhibitor-I enhances radiosensitivity of glioblastoma cell lines by depleting CD133+ tumor cells

21 January 2018

1 reference

BMI1 Confers Radioresistance to Normal and Cancerous Neural Stem Cells through Recruitment of the DNA Damage Response Machinery

21 January 2018

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CD133+ glioblastoma stem-like cells are radiosensitive with a defective DNA damage response compared with established cell lines.

21 January 2018

1 reference

Oct-4 expression maintained cancer stem-like properties in lung cancer-derived CD133-positive cells

21 January 2018

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Selection of radioresistant tumor cells and presence of ALDH1 activity in vitro.

21 January 2018

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CD133 expression is not selective for tumor-initiating or radioresistant cell populations in the CRC cell line HCT-116.

21 January 2018

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Effects of carbon ion beam on putative colon cancer stem cells and its comparison with X-rays

21 January 2018

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

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Maintenance of HCT116 colon cancer cell line conforms to a stochastic model but not a cancer stem cell model.

21 January 2018

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Temozolomide preferentially depletes cancer stem cells in glioblastoma

21 January 2018

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

1 reference

Identification and expansion of the tumorigenic lung cancer stem cell population

21 January 2018

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Aldehyde dehydrogenase 1 is a tumor stem cell-associated marker in lung cancer

21 January 2018

1 reference

CD133 expression and identification of CD133/nestin positive cells in rhabdomyosarcomas and rhabdomyosarcoma cell lines.

21 January 2018

1 reference

Cancer stem cell marker CD133+ tumour cells and clinical outcome in rectal cancer

21 January 2018

1 reference

Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells

21 January 2018

1 reference

Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue.

21 January 2018

1 reference

Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling

21 January 2018

1 reference

Hedgehog controls neural stem cells through p53-independent regulation of Nanog

21 January 2018

1 reference

Human term placenta as a source of hematopoietic cells

21 January 2018

1 reference

Adult human CD133/1(+) kidney cells isolated from papilla integrate into developing kidney tubules

21 January 2018

1 reference

The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives

21 January 2018

1 reference

CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

21 January 2018

1 reference

Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling

21 January 2018

1 reference

Stem cell patterns in cell lines derived from head and neck squamous cell carcinoma

21 January 2018

1 reference

Human mesenchymal stem cells form multicellular structures in response to applied cyclic strain.

21 January 2018

1 reference

Accelerated variant of idiopathic pulmonary fibrosis: clinical behavior and gene expression pattern

21 January 2018

1 reference

Novel germ cell markers characterize testicular seminoma and fetal testis

21 January 2018

1 reference

Prognostic impact of the expression of putative cancer stem cell markers CD133, CD166, CD44s, EpCAM, and ALDH1 in colorectal cancer.

21 January 2018

1 reference

ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients

21 January 2018

1 reference

Establishment and characterization of a novel head and neck squamous cell carcinoma cell line USC-HN1.

21 January 2018

1 reference

USC-HN2, a new model cell line for recurrent oral cavity squamous cell carcinoma with immunosuppressive characteristics.

21 January 2018

1 reference

Detection and characterization of CD133+ cancer stem cells in human solid tumours

21 January 2018

1 reference

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

21 January 2018

1 reference

A mosaic mouse model of astrocytoma identifies alphavbeta8 integrin as a negative regulator of tumor angiogenesis

21 January 2018

1 reference

Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma

21 January 2018

1 reference

Cell cycle-dependent variation of a CD133 epitope in human embryonic stem cell, colon cancer, and melanoma cell lines

21 January 2018

1 reference

CD133 identifies perivascular niches in grade II-IV astrocytomas.

21 January 2018

1 reference

Distribution of CD133 reveals glioma stem cells self-renew through symmetric and asymmetric cell divisions

21 January 2018

1 reference

Identification of a novel monoclonal antibody recognizing CD133

21 January 2018

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Identification of cancer stem cells in Ewing's sarcoma

21 January 2018

1 reference

Circulating tumor cells from patients with advanced prostate and breast cancer display both epithelial and mesenchymal markers

21 January 2018

1 reference

Prognostic impact of CD133 expression as a tumor-initiating cell marker in endometrial cancer

21 January 2018

1 reference

Comparative analysis of tumorbiology and CD133 positivity in primary and recurrent pancreatic ductal adenocarcinoma

21 January 2018

1 reference

Diabetes-relevant regulation of cultured blood outgrowth endothelial cells

21 January 2018

1 reference

Bone marrow-derived endothelial progenitor cells: a promising therapeutic alternative for corneal endothelial dysfunction.

21 January 2018

1 reference

Differential membrane proteomics using 18O-labeling to identify biomarkers for cholangiocarcinoma

21 January 2018

1 reference

Transmyocardial laser revascularization combined with intramyocardial endothelial progenitor cell transplantation in patients with intractable ischemic heart disease ineligible for conventional revascularization: preliminary results in a highly sele

21 January 2018

1 reference

Evidence for cell fusion is absent in vascular lesions associated with pulmonary arterial hypertension

21 January 2018

1 reference

Targeting CD133 antigen in cancer

21 January 2018

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Two novel monoclonal antibodies against human CD133-2: distinct epitopes and agonist activity to enhance growth of CD133 expression cells in vitro

21 January 2018

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Anti-human CD133 monoclonal antibody that could inhibit the proliferation of colorectal cancer cells

21 January 2018

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Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.

21 January 2018

1 reference

Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma.

21 January 2018

1 reference

Limits of CD133 as a marker of glioma self-renewing cells.

21 January 2018

1 reference

The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotype

21 January 2018

1 reference

High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.

21 January 2018

1 reference

CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer

21 January 2018

1 reference

Biological and genetic characteristics of tumor-initiating cells in colon cancer

21 January 2018

1 reference

Expansion of CD133(+) colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery

21 January 2018

1 reference

CD133+CD44+ population efficiently enriches colon cancer initiating cells

21 January 2018

1 reference

CD133, one of the markers of cancer stem cells in Hep-2 cell line

21 January 2018

1 reference

In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep-2 cell line

21 January 2018

1 reference

A subpopulation of CD133(+) cancer stem-like cells characterized in human oral squamous cell carcinoma confer resistance to chemotherapy

21 January 2018

1 reference

CD133+ renal progenitor cells contribute to tumor angiogenesis

21 January 2018

1 reference

Identification and metastatic potential of tumor-initiating cells in malignant rhabdoid tumor of the kidney

21 January 2018

1 reference

CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity

21 January 2018

1 reference

Identification and characterization of tumorigenic liver cancer stem/progenitor cells

21 January 2018

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Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations.

21 January 2018

1 reference

Achaete-scute complex homologue 1 regulates tumor-initiating capacity in human small cell lung cancer.

21 January 2018

1 reference

Cucurbitacin I inhibits tumorigenic ability and enhances radiochemosensitivity in nonsmall cell lung cancer-derived CD133-positive cells.

21 January 2018

1 reference

Expression of CD133-1 and CD133-2 in ovarian cancer

21 January 2018

1 reference

CD133-expressing stem cells associated with ovarian metastases establish an endothelial hierarchy and contribute to tumor vasculature

21 January 2018

1 reference

Cells with characteristics of cancer stem/progenitor cells express the CD133 antigen in human endometrial tumors

21 January 2018

1 reference

Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival

21 January 2018

1 reference

Expression of aldehyde dehydrogenase and CD133 defines ovarian cancer stem cells

21 January 2018

1 reference

ALDH activity selectively defines an enhanced tumor-initiating cell population relative to CD133 expression in human pancreatic adenocarcinoma

21 January 2018

1 reference

Prospective identification of tumorigenic prostate cancer stem cells

21 January 2018

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Side population rather than CD133(+) cells distinguishes enriched tumorigenicity in hTERT-immortalized primary prostate cancer cells

21 January 2018

1 reference

Identification of gastric cancer stem cells using the cell surface marker CD44.

21 January 2018

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CD133 and CD44 cell surface markers do not identify cancer stem cells in primary human gastric tumors

21 January 2018

1 reference

CD133 expression in chemo-resistant Ewing sarcoma cells

21 January 2018

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Human primary bone sarcomas contain CD133+ cancer stem cells displaying high tumorigenicity in vivo.

21 January 2018

1 reference

Melanoma contains CD133 and ABCG2 positive cells with enhanced tumourigenic potential.

21 January 2018

1 reference

The stem cell-associated antigen CD133 (Prominin-1) is a molecular therapeutic target for metastatic melanoma

21 January 2018

1 reference

Persistent use of "false" cell lines

21 January 2018

1 reference

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis.

21 January 2018

1 reference

Clinicopathological significance and prognostic value of CD133 expression in triple-negative breast carcinoma.

21 January 2018

1 reference

Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB

21 January 2018

1 reference

Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients.

21 January 2018

1 reference

Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients.

21 January 2018

1 reference

Immunohistochemical detection of CD133 expression in colorectal cancer: a clinicopathological study.

21 January 2018

1 reference

CD133 expression in rectal cancer after preoperative chemoradiotherapy.

21 January 2018

1 reference

Immunohistochemical analysis of tumour regression grade for rectal cancer after neoadjuvant chemoradiotherapy.

21 January 2018

1 reference

Differential role of CD133 and CXCR4 in renal cell carcinoma

21 January 2018

1 reference

Mixed phenotype hepatocellular carcinoma after transarterial chemoembolization and liver transplantation.

21 January 2018

1 reference

CD133 expression associated with poor prognosis in ovarian cancer

21 January 2018

1 reference

CD133 antigen expression in ovarian cancer

21 January 2018

1 reference

CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer

21 January 2018

1 reference

Aberrant expression of CD133 protein correlates with Ki-67 expression and is a prognostic marker in gastric adenocarcinoma

21 January 2018

1 reference

Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma

21 January 2018

1 reference

Expression profiling of GIST: CD133 is associated with KIT exon 11 mutations, gastric location and poor prognosis.

21 January 2018

1 reference

Sequential expression of putative stem cell markers in gastric carcinogenesis

21 January 2018

1 reference

Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells.

21 January 2018

1 reference

Targeting colorectal cancer stem cells with inducible caspase-9

21 January 2018

1 reference

Characterization of a side population of cancer cells from human gastrointestinal system

21 January 2018

1 reference

CD133+ liver cancer stem cells modulate radioresistance in human hepatocellular carcinoma

21 January 2018

1 reference

Targeting signal transducer and activator of transcription 3 pathway by cucurbitacin I diminishes self-renewing and radiochemoresistant abilities in thyroid cancer-derived CD133+ cells.

21 January 2018

1 reference

ABCB5-mediated doxorubicin transport and chemoresistance in human malignant melanoma

21 January 2018

1 reference

Combined CD133/CD44 expression as a prognostic indicator of disease-free survival in patients with colorectal cancer.

21 January 2018

1 reference

CD44 is of Functional Importance for Colorectal Cancer Stem Cells

21 January 2018

1 reference

Human skin-derived stem cells migrate throughout forebrain and differentiate into astrocytes after injection into adult mouse brain

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/PATH.4086

1 reference

27 August 2017

1 reference