(Q38040025)

27 August 2017

TAK1, more than just innate immunity (English)

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27 August 2017

Liang Dai

1

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27 August 2017

Chan Aye Thu

2

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27 August 2017

Xin-Yu Liu

3

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27 August 2017

Jiajia Xi

4

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27 August 2017

Peter C F Cheung

5

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27 August 2017

3 September 2012

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27 August 2017

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27 August 2017

64

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27 August 2017

10

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27 August 2017

825-834

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Toll-like receptor signaling

27 August 2017

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An evolutionarily conserved motif in the TAB1 C-terminal region is necessary for interaction with and activation of TAK1 MAPKKK

21 January 2018

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TAB3, a new binding partner of the protein kinase TAK1

21 January 2018

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Role of the TAB2-related protein TAB3 in IL-1 and TNF signaling

21 January 2018

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Essential function for the kinase TAK1 in innate and adaptive immune responses.

21 January 2018

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TAK1 is a central mediator of NOD2 signaling in epidermal cells

21 January 2018

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Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

21 January 2018

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TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains

21 January 2018

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TAK1-dependent signaling requires functional interaction with TAB2/TAB3

21 January 2018

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Direct activation of protein kinases by unanchored polyubiquitin chains

21 January 2018

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Autoactivation of transforming growth factor beta-activated kinase 1 is a sequential bimolecular process

21 January 2018

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Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2.

21 January 2018

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Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by NZF domains of TAB2 and TAB3

21 January 2018

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Structural basis for the interaction of TAK1 kinase with its activating protein TAB1.

21 January 2018

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TAK1-binding protein 1 is a pseudophosphatase.

21 January 2018

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TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling

21 January 2018

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Transforming growth factor-beta (TGF-beta1) activates TAK1 via TAB1-mediated autophosphorylation, independent of TGF-beta receptor kinase activity in mesangial cells

21 January 2018

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Roles for TAB1 in regulating the IL-1-dependent phosphorylation of the TAB3 regulatory subunit and activity of the TAK1 complex

21 January 2018

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XIAP Induces NF-κB Activation via the BIR1/TAB1 Interaction and BIR1 Dimerization

21 January 2018

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Feedback control of the protein kinase TAK1 by SAPK2a/p38

21 January 2018

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O-GlcNAcylation of TAB1 modulates TAK1-mediated cytokine release.

21 January 2018

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

21 January 2018

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Essential role of TAK1 in thymocyte development and activation.

21 January 2018

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TAK1 is indispensable for development of T cells and prevention of colitis by the generation of regulatory T cells.

21 January 2018

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The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function.

21 January 2018

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A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation

21 January 2018

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ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress

21 January 2018

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A cytosolic ATM/NEMO/RIP1 complex recruits TAK1 to mediate the NF-kappaB and p38 mitogen-activated protein kinase (MAPK)/MAPK-activated protein 2 responses to DNA damage

21 January 2018

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A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation.

21 January 2018

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LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO

21 January 2018

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The TAK1-NLK-MAPK-related pathway antagonizes signalling between beta-catenin and transcription factor TCF.

21 January 2018

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Wnt activates the Tak1/Nemo-like kinase pathway

21 January 2018

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The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.

21 January 2018

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Wnt-1 signal induces phosphorylation and degradation of c-Myb protein via TAK1, HIPK2, and NLK

21 January 2018

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Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction

21 January 2018

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A direct interaction between TGFbeta activated kinase 1 and the TGFbeta type II receptor: implications for TGFbeta signalling and cardiac hypertrophy

21 January 2018

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ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factor-beta signaling

21 January 2018

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TRAF6 mediates Smad-independent activation of JNK and p38 by TGF-beta

21 January 2018

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The TGF beta activated kinase TAK1 regulates vascular development in vivo

21 January 2018

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The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent manner

21 January 2018

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TAK1 lysine 158 is required for TGF-β-induced TRAF6-mediated Smad-independent IKK/NF-κB and JNK/AP-1 activation

21 January 2018

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Interaction between TAK1-TAB1-TAB2 and RCAN1-calcineurin defines a signalling nodal control point

21 January 2018

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XIAP, a cellular member of the inhibitor of apoptosis protein family, links the receptors to TAB1-TAK1 in the BMP signaling pathway

21 January 2018

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Role of TAK1 and TAB1 in BMP signaling in early Xenopus development

21 January 2018

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Regulation of MAP kinase by the BMP-4/TAK1 pathway in Xenopus ectoderm

21 January 2018

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Bone morphogenetic proteins induce cardiomyocyte differentiation through the mitogen-activated protein kinase kinase kinase TAK1 and cardiac transcription factors Csx/Nkx-2.5 and GATA-4

21 January 2018

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TAK1 is an essential regulator of BMP signalling in cartilage

21 January 2018

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Transforming growth factor-beta-activated kinase-1 (TAK1), a MAP3K, interacts with Smad proteins and interferes with osteogenesis in murine mesenchymal progenitors

21 January 2018

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Regulation of RANKL-induced osteoclastogenesis by TGF-β through molecular interaction between Smad3 and Traf6.

21 January 2018

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TAK1 MAPK kinase kinase mediates transforming growth factor-beta signaling by targeting SnoN oncoprotein for degradation

21 January 2018

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TAK1 mediates BMP signaling in cartilage

21 January 2018

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Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2.

21 January 2018

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Osmotic stress activates the TAK1-JNK pathway while blocking TAK1-mediated NF-kappaB activation: TAO2 regulates TAK1 pathways

21 January 2018

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Mechanism of hypoxia-induced NF-kappaB.

21 January 2018

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Further insights into the mechanism of hypoxia-induced NFκB. [corrected].

21 January 2018

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21 January 2018

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Mammalian TAK1 activates Snf1 protein kinase in yeast and phosphorylates AMP-activated protein kinase in vitro

21 January 2018

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A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway

21 January 2018

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TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells.

21 January 2018

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Regulation of the TAK1 signaling pathway by protein phosphatase 2C

21 January 2018

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Regulation of the interleukin-1-induced signaling pathways by a novel member of the protein phosphatase 2C family (PP2Cepsilon)

21 January 2018

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Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway

21 January 2018

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Transforming growth factor beta-activated kinase 1 (TAK1) kinase adaptor, TAK1-binding protein 2, plays dual roles in TAK1 signaling by recruiting both an activator and an inhibitor of TAK1 kinase in tumor necrosis factor signaling pathway

21 January 2018

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Protein phosphatase 2A is a negative regulator of transforming growth factor-beta1-induced TAK1 activation in mesangial cells

21 January 2018

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Deubiquitinating enzyme CYLD negatively regulates the ubiquitin-dependent kinase Tak1 and prevents abnormal T cell responses

21 January 2018

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The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation

21 January 2018

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USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation

21 January 2018

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A histone lysine methyltransferase activated by non-canonical Wnt signalling suppresses PPAR-gamma transactivation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IUB.1078

1 reference

27 August 2017

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