(Q38041858)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

The roles and therapeutic potentials of Ephs and ephrins in lung cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Jing-Jing Li

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

31 August 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

Experimental Cell Research

12 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

319

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

152-159

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008

12 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Eph receptor tyrosine kinases in tumor and tumor microenvironment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

The ephrins and Eph receptors in neural development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Patterns of somatic mutation in human cancer genomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Somatic mutations of the protein kinase gene family in human lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Somatic mutations affect key pathways in lung adenocarcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Somatic mutations of GUCY2F, EPHA3, and NTRK3 in human cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Cancer somatic mutations disrupt functions of the EphA3 receptor tyrosine kinase through multiple mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphA2 in the early pathogenesis and progression of non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Expression of the receptor tyrosine kinase EphA2 is increased in smokers and predicts poor survival in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

A conditional feedback loop regulates Ras activity through EphA2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

The EPHB6 receptor tyrosine kinase is a metastasis suppressor that is frequently silenced by promoter DNA hypermethylation in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Mechanisms and functions of Eph and ephrin signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Receptor EphA2 activation with ephrinA1 suppresses growth of malignant mesothelioma (MM).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Targeted lung cancer therapy using ephrinA1-loaded albumin microspheres

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphB3 is overexpressed in non-small-cell lung cancer and promotes tumor metastasis by enhancing cell survival and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Phosphoproteomic profiling of NSCLC cells reveals that ephrin B3 regulates pro-survival signaling through Akt1-mediated phosphorylation of the EphA2 receptor.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Complexes of focal adhesion kinase (FAK) and Crk-associated substrate (p130(Cas)) are elevated in cytoskeleton-associated fractions following adhesion and Src transformation. Requirements for Src kinase activity and FAK proline-rich motifs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas).

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Receptor tyrosine kinase EphB4 is a survival factor in breast cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphA2 mediates ligand-dependent inhibition and ligand-independent promotion of cell migration and invasion via a reciprocal regulatory loop with Akt

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

The ephrins and Eph receptors in angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Role of ephrinB2 in nonproductive angiogenesis induced by Delta-like 4 blockade

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Gene expression profiling of normal human pulmonary fibroblasts following coculture with non-small-cell lung cancer cells reveals alterations related to matrix degradation, angiogenesis, cell growth and survival

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Cancer cells exploit the Eph-ephrin system to promote invasion and metastasis: tales of unwitting partners

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Recent advances on T-cell regulation by receptor tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Putative dual role of ephrin-Eph receptor interactions in inflammation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Identification of candidate molecular markers predicting sensitivity in solid tumors to dasatinib: rationale for patient selection

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Effects of dasatinib on EphA2 receptor tyrosine kinase activity and downstream signalling in pancreatic cancer.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

A chemical and phosphoproteomic characterization of dasatinib action in lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Phase II study of dasatinib in patients with advanced non-small-cell lung cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Small molecules can selectively inhibit ephrin binding to the EphA4 and EphA2 receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphB receptor-binding peptides identified by phage display enable design of an antagonist with ephrin-like affinity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Inhibition of Eph receptor-ephrin ligand interaction by tea polyphenols

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Distinctive binding of three antagonistic peptides to the ephrin-binding pocket of the EphA4 receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphA2 targeted chemotherapy using an antibody drug conjugate in endometrial carcinoma

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Efficacy and antivascular effects of EphA2 reduction with an agonistic antibody in ovarian cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

Differential gene expression of Eph receptors and ephrins in benign human tissues and cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2012.08.005

10.1016/J.YEXCR.2012.08.005

7 January 2021

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22960108%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference