(Q38045235)

27 August 2017

title

From sentinel cells to inflammatory culprits: cancer-associated fibroblasts in tumour-related inflammation (English)

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cancer-associated fibroblast

27 August 2017

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2

Neta Erez

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27 August 2017

Charlotte Servais

1

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27 August 2017

publication date

20 November 2012

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27 August 2017

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27 August 2017

volume

229

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27 August 2017

issue

2

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27 August 2017

page(s)

198-207

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27 August 2017

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Inflammation and cancer: back to Virchow?

21 January 2018

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21 January 2018

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21 January 2018

Inflammation and cancer

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Accessories to the crime: functions of cells recruited to the tumor microenvironment

21 January 2018

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Microenvironmental regulation of metastasis

21 January 2018

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A CXCL1 paracrine network links cancer chemoresistance and metastasis

21 January 2018

1 reference

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

21 January 2018

1 reference

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

21 January 2018

1 reference

Fibroblasts regulate the switch from acute resolving to chronic persistent inflammation.

21 January 2018

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Stromal induction of breast cancer: inflammation and invasion

21 January 2018

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Molecular characterization of the tumor microenvironment in breast cancer

21 January 2018

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Stromal fibroblasts in cancer initiation and progression

21 January 2018

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Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

21 January 2018

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21 January 2018

Fibroblasts in cancer

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Hallmarks of cancer: interactions with the tumor stroma.

21 January 2018

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Activation of fibroblasts in cancer stroma

21 January 2018

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Three-dimensional context regulation of metastasis

21 January 2018

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Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

21 January 2018

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

21 January 2018

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Fibroblasts--a key host cell type in tumor initiation, progression, and metastasis

21 January 2018

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TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia

21 January 2018

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Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks

21 January 2018

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

21 January 2018

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Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320

21 January 2018

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High-throughput live-cell imaging reveals differential inhibition of tumor cell proliferation by human fibroblasts

21 January 2018

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Nod-like receptor pyrin domain-containing protein 6 (NLRP6) controls epithelial self-renewal and colorectal carcinogenesis upon injury

21 January 2018

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NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis

21 January 2018

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Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression

21 January 2018

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Rheumatoid arthritis progression mediated by activated synovial fibroblasts

21 January 2018

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Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

21 January 2018

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Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds

21 January 2018

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Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

21 January 2018

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Bone marrow-derived myofibroblasts contribute to the mesenchymal stem cell niche and promote tumor growth.

21 January 2018

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Stromal COX-2 signaling activated by deoxycholic acid mediates proliferation and invasiveness of colorectal epithelial cancer cells.

21 January 2018

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IL1β-mediated Stromal COX-2 signaling mediates proliferation and invasiveness of colonic epithelial cancer cells

21 January 2018

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Identification of CXCL5/ENA-78 as a factor involved in the interaction between cholangiocarcinoma cells and cancer-associated fibroblasts

21 January 2018

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Contribution of Fibroblast and Mast Cell (Afferent) and Tumor (Efferent) IL-6 Effects within the Tumor Microenvironment

21 January 2018

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From mechanotransduction to extracellular matrix gene expression in fibroblasts.

21 January 2018

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Mechanics, malignancy, and metastasis: the force journey of a tumor cell

21 January 2018

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Human periodontal ligament fibroblasts stimulate osteoclastogenesis in response to compression force through TNF-α-mediated activation of CD4+ T cells.

21 January 2018

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Involvement of JNK-AP-1 and ERK-NF-κB signaling in tension-stimulated expression of type I collagen and MMP-1 in human periodontal ligament fibroblasts

21 January 2018

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Focal adhesion kinase links mechanical force to skin fibrosis via inflammatory signaling.

21 January 2018

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The functional role of reactive stroma in benign prostatic hyperplasia

21 January 2018

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The inflammatory microenvironment of the aging prostate facilitates cellular proliferation and hypertrophy

21 January 2018

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The effects of aging on the molecular and cellular composition of the prostate microenvironment

21 January 2018

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FcRgamma activation regulates inflammation-associated squamous carcinogenesis.

21 January 2018

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De novo carcinogenesis promoted by chronic inflammation is B lymphocyte dependent

21 January 2018

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La mala educación of Tumor-Associated Macrophages: Diverse Pathways and New Players

21 January 2018

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Stromal fibroblasts in colorectal liver metastases originate from resident fibroblasts and generate an inflammatory microenvironment

21 January 2018

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21 January 2018

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Gene expression profiling reveals cross-talk between melanoma and fibroblasts: implications for host-tumor interactions in metastasis

21 January 2018

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Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

21 January 2018

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Monocyte chemoattractant protein-1: a key mediator in inflammatory processes.

21 January 2018

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Importance of CCL2-CCR2A/2B signaling for monocyte migration into spheroids of breast cancer-derived fibroblasts

21 January 2018

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Tumor-associated fibroblasts recruit blood monocytes into tumor tissue

21 January 2018

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Loss of transforming growth factor-beta signaling in mammary fibroblasts enhances CCL2 secretion to promote mammary tumor progression through macrophage-dependent and -independent mechanisms

21 January 2018

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CXCL14 is an autocrine growth factor for fibroblasts and acts as a multi-modal stimulator of prostate tumor growth

21 January 2018

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Hyaluronan Deficiency in Tumor Stroma Impairs Macrophage Trafficking and Tumor Neovascularization

21 January 2018

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Sterile inflammation: sensing and reacting to damage

21 January 2018

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

21 January 2018

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T cells and stromal fibroblasts in human tumor microenvironments represent potential therapeutic targets

21 January 2018

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Immunosuppressive networks in the tumour environment and their therapeutic relevance

21 January 2018

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TGF-beta 1 attenuates the acquisition and expression of effector function by tumor antigen-specific human memory CD8 T cells

21 January 2018

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TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression

21 January 2018

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Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

21 January 2018

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The fibroblast: sentinel cell and local immune modulator in tumor tissue

21 January 2018

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Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model

21 January 2018

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Intratumor T helper type 2 cell infiltrate correlates with cancer-associated fibroblast thymic stromal lymphopoietin production and reduced survival in pancreatic cancer

21 January 2018

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Th17 cells in cancer: help or hindrance?

21 January 2018

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Tumor microenvironments direct the recruitment and expansion of human Th17 cells

21 January 2018

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Regulatory T cells in gastrointestinal tumors

21 January 2018

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Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling

21 January 2018

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The serial cultivation of human diploid cell strains

21 January 2018

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

21 January 2018

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Senescent cells as a source of inflammatory factors for tumor progression

21 January 2018

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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

21 January 2018

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The senescence-associated secretory phenotype: the dark side of tumor suppression

21 January 2018

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

21 January 2018

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Chromatin remodeling underlies the senescence-associated secretory phenotype of tumor stromal fibroblasts that supports cancer progression

21 January 2018

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Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP).

21 January 2018

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Control of the senescence-associated secretory phenotype by NF-κB promotes senescence and enhances chemosensitivity

21 January 2018

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Osteopontin stimulates preneoplastic cellular proliferation through activation of the MAPK pathway

21 January 2018

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21 January 2018

Cancer without disease.

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Metastasis: from dissemination to organ-specific colonization

21 January 2018

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Systemic endocrine instigation of indolent tumor growth requires osteopontin

21 January 2018

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Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice

21 January 2018

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The secreted factors responsible for pre-metastatic niche formation: old sayings and new thoughts.

21 January 2018

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VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization

21 January 2018

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Interactions between cancer stem cells and their niche govern metastatic colonization

21 January 2018

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Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

21 January 2018

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Extracellular matrix players in metastatic niches

21 January 2018

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Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity

21 January 2018

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Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

21 January 2018

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Cellular fibronectin binds to lysyl oxidase with high affinity and is critical for its proteolytic activation

21 January 2018

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Allosteric inhibition of lysyl oxidase–like-2 impedes the development of a pathologic microenvironment

21 January 2018

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Malignant cells facilitate lung metastasis by bringing their own soil

21 January 2018

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

21 January 2018

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S1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.

21 January 2018

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Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis

21 January 2018

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Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs.

21 January 2018

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

21 January 2018

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Leukocytes as paracrine regulators of metastasis and determinants of organ-specific colonization

21 January 2018

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The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/PATH.4103

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27 August 2017

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