(Q38045418)

27 August 2017

title

Inhibition and induction of glutathione S-transferases by flavonoids: possible pharmacological and toxicological consequences (English)

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27 August 2017

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1 reference

Iva Boušová

1

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27 August 2017

Lenka Skálová

series ordinal

2

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27 August 2017

language of work or name

English

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publication date

24 September 2012

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27 August 2017

published in

Drug Metabolism Reviews

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27 August 2017

volume

44

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27 August 2017

issue

4

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27 August 2017

page(s)

267-286

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Characterization and localization of glutathione-S-transferases in rat brain and binding of hormones, neurotransmitters, and drugs

27 August 2017

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21 January 2018

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Characterization of a fungal maleylacetoacetate isomerase gene and identification of its human homologue

21 January 2018

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Glutathione transferases in the genomics era: new insights and perspectives.

21 January 2018

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Regulation of phase II enzymes by genistein and daidzein in male and female Swiss Webster mice

21 January 2018

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Dietary polyphenols: good, bad, or indifferent for your health?

21 January 2018

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Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?

21 January 2018

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Possibilities to increase the effectiveness of doxorubicin in cancer cells killing.

21 January 2018

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21 January 2018

Glutathione transferases

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

21 January 2018

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Human glutathione transferase A3-3, a highly efficient catalyst of double-bond isomerization in the biosynthetic pathway of steroid hormones

21 January 2018

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21 January 2018

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21 January 2018

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Activation of CCAAT/enhancer-binding protein beta by 2'-amino-3'-methoxyflavone (PD98059) leads to the induction of glutathione S-transferase A2.

21 January 2018

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Anti- and pro-oxidant activity of rutin and quercetin derivatives

21 January 2018

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Dynamics of neutrophil extravasation and vascular permeability are uncoupled during aseptic cutaneous wounding

21 January 2018

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Characterization of bromosulphophthalein binding to human glutathione S-transferase A1-1: thermodynamics and inhibition kinetics

21 January 2018

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Signal transduction events elicited by cancer prevention compounds

21 January 2018

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Effect of Cistus laurifolius L. leaf extracts and flavonoids on acetaminophen-induced hepatotoxicity in mice

21 January 2018

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Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death

21 January 2018

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Glutathione S-transferase m1 and t1 null genotypes increase susceptibility to idiosyncratic drug-induced liver injury.

21 January 2018

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Kinetic characterization of native and cysteine 112-modified glutathione S-transferase A1-1: reassessment of nonsubstrate ligand binding

21 January 2018

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Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification

21 January 2018

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The chemistry and biology of inhibitors and pro-drugs targeted to glutathione S-transferases

21 January 2018

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Tea consumption modulates hepatic drug metabolizing enzymes in Wistar rats

21 January 2018

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Nomenclature for mammalian soluble glutathione transferases

21 January 2018

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Modulation of metabolic enzymes by dietary phytochemicals: a review of mechanisms underlying beneficial versus unfavorable effects

21 January 2018

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Inhibition of rat liver sulfotransferases SULT1A1 and SULT2A1 and glucuronosyltransferase by dietary flavonoids

21 January 2018

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Interactions of flavonoids with iron and copper ions: a mechanism for their antioxidant activity.

21 January 2018

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Isozyme- and gender-specific induction of glutathione S-transferases by flavonoids

21 January 2018

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Glutathione S-transferase-pi overexpression is closely associated with K-ras mutation during human colon carcinogenesis

21 January 2018

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Dietary flavonoids: effects on xenobiotic and carcinogen metabolism

21 January 2018

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Gene and protein characterization of the human glutathione S-transferase kappa and evidence for a peroxisomal localization

21 January 2018

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2'-hydroxyflavanone inhibits proliferation, tumor vascularization and promotes normal differentiation in VHL-mutant renal cell carcinoma

21 January 2018

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Enhancement of rat hepatic and gastrointestinal glutathione and glutathione S-transferases by alpha-angelicalactone and flavone.

21 January 2018

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Tissue-specific mRNA expression profiles of human phase I metabolizing enzymes except for cytochrome P450 and phase II metabolizing enzymes

21 January 2018

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Functions of the breast cancer resistance protein (BCRP/ABCG2) in chemotherapy.

21 January 2018

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The ligandin (non-substrate) binding site of human Pi class glutathione transferase is located in the electrophile binding site (H-site)

21 January 2018

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Glutathione transferases: a structural perspective

21 January 2018

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GSTT1, GSTM1, and GSTP1 polymorphisms and chemotherapy response in locally advanced breast cancer

21 January 2018

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Antioxidants and oxidants regulated signal transduction pathways

21 January 2018

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Catechin prevents tamoxifen-induced oxidative stress and biochemical perturbations in mice.

21 January 2018

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Dynamics of glutathione conjugation and conjugate efflux in detoxification of the carcinogen, 4-nitroquinoline 1-oxide: contributions of glutathione, glutathione S-transferase, and MRP1.

21 January 2018

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Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

21 January 2018

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Flavonoids as antioxidants

21 January 2018

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Crystal structure of maleylacetoacetate isomerase/glutathione transferase zeta reveals the molecular basis for its remarkable catalytic promiscuity

21 January 2018

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Structures of class pi glutathione S-transferase from human placenta in complex with substrate, transition-state analogue and inhibitor

21 January 2018

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Antioxidant and prooxidant properties of flavonoids.

21 January 2018

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Glutathione S-transferases and thiol concentrations in embryonic and early fetal tissues

21 January 2018

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Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Role of residue 87 in the activity and regioselectivity of clozapine metabolism by drug-metabolizing CYP102A1 M11H: application for structural characterization of clozapine GSH conjugates

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin.

21 January 2018

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Structure-antioxidant activity relationships of flavonoids and phenolic acids

21 January 2018

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Interactions of polyphenols with the P450 system: possible implications on human therapeutics

21 January 2018

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Human GSTA1-1 reduces c-Jun N-terminal kinase signalling and apoptosis in Caco-2 cells

21 January 2018

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The influence of diet composition on phase I and II biotransformation enzyme induction

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione transferases as targets for cancer therapy.

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Negative regulation of MEKK1-induced signaling by glutathione S-transferase Mu.

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione transferases and development of new principles to overcome drug resistance

21 January 2018

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Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines.

21 January 2018

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Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Do glutathione-S-transferase polymorphisms influence response to intravenous cyclophosphamide therapy in idiopathic nephrotic syndrome?

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Anthracycline-induced cardiotoxicity: overview of studies examining the roles of oxidative stress and free cellular iron

21 January 2018

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In vitro antifilarial activity of glutathione S-transferase inhibitors.

21 January 2018

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Glutathione S-transferase M1 polymorphism: a risk factor for hepatic venoocclusive disease in bone marrow transplantation

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Drug combinations with quercetin: doxorubicin plus quercetin in human breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Structural characterization of in vivo rat glutathione adducts and a hydroxylated metabolite of simvastatin hydroxy acid

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

New cancer treatment strategy using combination of green tea catechins and anticancer drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Interactions between sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

The role of glutathione S-transferase P in signaling pathways and S-glutathionylation in cancer

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Protective effect of the cruciferous vegetable mustard leaf (Brassica campestris) against in vivo chromosomal damage and oxidative stress induced by gamma-radiation and genotoxic chemicals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione transferases from parasites: a biochemical view

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione S-transferases as regulators of kinase pathways and anticancer drug targets

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

The role of glutathione-S-transferase in anti-cancer drug resistance

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Novel role for glutathione S-transferase pi. Regulator of protein S-Glutathionylation following oxidative and nitrosative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Protective effect of catechin and quercetin on chlorpyrifos-induced lung toxicity in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione conjugation as a bioactivation reaction

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

The inhibition of glutathione S-transferases: Mechanisms, toxic consequences and therapeutic benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Effects of dietary anticarcinogens on rat gastrointestinal glutathione S-transferase theta 1-1 levels

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Inhibition of human glutathione S-transferase P1-1 by the flavonoid quercetin

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Identification of quinone imine containing glutathione conjugates of diclofenac in rat bile

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Hypolipidaemic and hypoglycaemic effects of total flavonoids from seed residues of Hippophae rhamnoides L. in mice fed a high-fat diet

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Glutathione S-transferase P1-1 (GSTP1-1) inhibits c-Jun N-terminal kinase (JNK1) signaling through interaction with the C terminus

21 January 2018

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https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Characterization of the human Omega class glutathione transferase genes and associated polymorphisms

21 January 2018

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Effects of quercetin and catechin on hepatic glutathione-S transferase (GST), NAD(P)H quinone oxidoreductase 1 (NQO1), and antioxidant enzyme activity levels in rats

21 January 2018

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Anthocyanins and other flavonoids.

21 January 2018

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Flavonoid biosynthesis. A colorful model for genetics, biochemistry, cell biology, and biotechnology

21 January 2018

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Characterization of glutathione conjugates of duloxetine by mass spectrometry and evaluation of in silico approaches to rationalize the site of conjugation for thiophene containing drugs

21 January 2018

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Human glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signals

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Induction of phase I, II and III drug metabolism/transport by xenobiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Immunohistochemistry of omega class glutathione S-transferase in human tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Inhibitory effects of plant polyphenols on rat liver glutathione S-transferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

Conjugation of chlorambucil with GSH by GST purified from human colon adenocarcinoma cells and its inhibition by plant polyphenols

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

The role of human glutathione S-transferases hGSTA1-1 and hGSTA2-2 in protection against oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F03602532.2012.713969

10.3109/03602532.2012.713969

21 January 2018

Identifiers

DOI

1 reference

27 August 2017

1 reference