(Q38050398)

27 August 2017

title

B cells and antibodies in multiple sclerosis pathogenesis and therapy (English)

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27 August 2017

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Markus Krumbholz

1

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27 August 2017

Tobias Derfuss

series ordinal

2

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27 August 2017

Reinhard Hohlfeld

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3

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27 August 2017

Edgar Meinl

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4

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27 August 2017

language of work or name

English

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publication date

9 October 2012

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27 August 2017

published in

Nature Reviews Neurology

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27 August 2017

volume

8

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27 August 2017

issue

11

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27 August 2017

page(s)

613-623

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Long-lived autoreactive plasma cells drive persistent autoimmune inflammation

27 August 2017

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Identification of naturally occurring fatty acids of the myelin sheath that resolve neuroinflammation

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Antigen microarrays identify unique serum autoantibody signatures in clinical and pathologic subtypes of multiple sclerosis

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Rituximab specifically depletes short-lived autoreactive plasma cells in a mouse model of inflammatory arthritis

21 January 2018

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21 January 2018

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21 January 2018

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Alemtuzumab more effective than interferon β-1a at 5-year follow-up of CAMMS223 clinical trial

21 January 2018

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Results from a human renal allograft tolerance trial evaluating the humanized CD52-specific monoclonal antibody alemtuzumab (CAMPATH-1H).

21 January 2018

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B-cell reconstitution and BAFF after alemtuzumab (Campath-1H) treatment of multiple sclerosis.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Novel function of B cell-activating factor in the induction of IL-10-producing regulatory B cells

21 January 2018

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Inverse association between circulating APRIL levels and serological and clinical disease activity in patients with systemic lupus erythematosus

21 January 2018

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Identification of BLyS (B lymphocyte stimulator), a non-myelin-associated protein, as a functional ligand for Nogo-66 receptor.

21 January 2018

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A BAFF antagonist suppresses experimental autoimmune encephalomyelitis by targeting cell-mediated and humoral immune responses

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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B lymphocytes exit lymph nodes through cortical lymphatic sinusoids by a mechanism independent of sphingosine-1-phosphate-mediated chemotaxis.

21 January 2018

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Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

21 January 2018

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Plasma cell S1P1 expression determines secondary lymphoid organ retention versus bone marrow tropism

21 January 2018

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Follicular shuttling of marginal zone B cells facilitates antigen transport

21 January 2018

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FTY720 in corneal concordant xenotransplantation.

21 January 2018

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Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers

21 January 2018

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Identification of short-term pharmacodynamic effects of interferon-beta-1a in multiple sclerosis subjects with broad- based phenotypic profiling.

21 January 2018

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21 January 2018

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B cells from glatiramer acetate-treated mice suppress experimental autoimmune encephalomyelitis

21 January 2018

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Antibody-independent B cell effector functions in relapsing remitting multiple sclerosis: clues to increased inflammatory and reduced regulatory B cell capacity.

21 January 2018

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Induction of apoptosis by dexamethasone in the B cell lineage.

21 January 2018

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Increased proliferation of blood mononuclear cells after plasmapheresis treatment of patients with demyelinating disease

21 January 2018

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Effects of plasmapheresis on peripheral blood mononuclear cell populations from patients with macroglobulinemia.

21 January 2018

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Drug Insight: the use of intravenous immunoglobulin in neurology--therapeutic considerations and practical issues

21 January 2018

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21 January 2018

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Modulatory effects of 1,25-dihydroxyvitamin D3 on human B cell differentiation.

21 January 2018

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Vitamin D and autoimmune thyroid diseases

21 January 2018

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Vitamin D and multiple sclerosis: epidemiology, immunology, and genetics

21 January 2018

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Effect of vitamin D(3) supplementation on peripheral B cell differentiation and isotype switching in patients with multiple sclerosis

21 January 2018

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Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Smoking is associated with increased lesion volumes and brain atrophy in multiple sclerosis

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Smoking and disease progression in multiple sclerosis

21 January 2018

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Environmental factors and their timing in adult-onset multiple sclerosis

21 January 2018

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Smoking and multiple sclerosis: an updated meta-analysis

21 January 2018

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Cigarette smoke-induced effects on bone marrow B-cell subsets and CD4+:CD8+ T-cell ratios are reversed by smoking cessation: influence of bone mass on immune cell response to and recovery from smoke exposure.

21 January 2018

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N-acetylcysteine increases the frequency of bone marrow pro-B/pre-B cells, but does not reverse cigarette smoking-induced loss of this subset

21 January 2018

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Impact of female cigarette smoking on circulating B cells in vivo: the suppressed ICOSLG, TCF3, and VCAM1 gene functional network may inhibit normal cell function

21 January 2018

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Clonal expansion and somatic hypermutation of V(H) genes of B cells from cerebrospinal fluid in multiple sclerosis.

21 January 2018

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Disruption of heparan sulfate proteoglycan conformation perturbs B-cell maturation and APRIL-mediated plasma cell survival.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Recombinant human acid [alpha]-glucosidase: major clinical benefits in infantile-onset Pompe disease

21 January 2018

1 reference

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Rituximab in patients with primary progressive multiple sclerosis: results of a randomized double-blind placebo-controlled multicenter trial

21 January 2018

1 reference

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Repeated treatment with rituximab based on the assessment of peripheral circulating memory B cells in patients with relapsing neuromyelitis optica over 2 years.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Rituximab reduces B cells and T cells in cerebrospinal fluid of multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Changes in B- and T-lymphocyte and chemokine levels with rituximab treatment in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Differential effects on BAFF and APRIL levels in rituximab-treated patients with systemic lupus erythematosus and rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Soluble BAFF levels inversely correlate with peripheral B cell numbers and the expression of BAFF receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

B cell repopulation after alemtuzumab induction-transient increase in transitional B cells and long-term dominance of naïve B cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Immunity 12 years after alemtuzumab in RA: CD5⁺ B-cell depletion, thymus-dependent T-cell reconstitution and normal vaccine responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

BAFF is increased in renal transplant patients following treatment with alemtuzumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Alemtuzumab as compared to alternative contemporary induction regimens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Preferential increase of B-cell activating factor in the cerebrospinal fluid of neuromyelitis optica in a white population

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Glatiramer acetate antibodies, gene expression and disease activity in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Treatment with glatiramer acetate induces specific IgG4 antibodies in multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Opposite effects of interferon-beta on new B and T cell release from production sites in multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

The role of differential IgG glycosylation in the interaction of antibodies with FcγRs in vivo

21 January 2018

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Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange

31 March 2020

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Intrathecal IgM synthesis in pediatric MS is not a negative prognostic marker of disease progression: quantitative versus qualitative IgM analysis

31 March 2020

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The intrathecal, polyspecific antiviral immune response: Specific for MS or a general marker of CNS autoimmunity?

31 March 2020

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The initiation and prevention of multiple sclerosis

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

CCL19 is constitutively expressed in the CNS, up-regulated in neuroinflammation, active and also inactive multiple sclerosis lesions

31 March 2020

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https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

The chemokine CXCL13 (BLC): a putative diagnostic marker for neuroborreliosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

BAFF-modulated repopulation of B lymphocytes in the blood and salivary glands of rituximab-treated patients with Sjögren's syndrome

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRNEUROL.2012.203

B cell depletion therapy in systemic lupus erythematosus: effect on autoantibody and antimicrobial antibody profiles

31 March 2020

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Long-term follow-up of patients with neuromyelitis optica after repeated therapy with rituximab

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Safety and efficacy of ocrelizumab in patients with rheumatoid arthritis and an inadequate response to at least one tumor necrosis factor inhibitor: results of a forty-eight–week randomized, double-blind, placebo-controlled, parallel-group phase III

31 March 2020

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Autoimmune disease after alemtuzumab treatment for multiple sclerosis in a multicenter cohort

31 March 2020

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Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double-blind, placebo-controlled, dose-escalating, single- and repeated-dose study

31 March 2020

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Differential effects of fingolimod (FTY720) on immune cells in the CSF and blood of patients with MS

31 March 2020

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Effects of natalizumab on circulating B cells, T regulatory cells and natural killer cells

31 March 2020

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CD49d blockade by natalizumab therapy in patients with multiple sclerosis increases immature B-lymphocytes

31 March 2020

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Pharmacodynamic effects of steady-state fingolimod on antibody response in healthy volunteers: a 4-week, randomized, placebo-controlled, parallel-group, multiple-dose study

31 March 2020

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Interferon-beta increases BAFF levels in multiple sclerosis: implications for B cell autoimmunity

31 March 2020

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Interferon beta-1b exacerbates multiple sclerosis with severe optic nerve and spinal cord demyelination

31 March 2020

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Glucocorticoid-induced apoptosis in early B cells from human bone marrow.

31 March 2020

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Apoptosis of ileal Peyer's patch B cells is increased by glucocorticoids or anti-immunoglobulin antibodies

31 March 2020

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Increased antibody production in peripheral blood mononuclear cells after plasma exchange therapy in multiple sclerosis

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BAFF is a biological response marker to IFN-beta treatment in multiple sclerosis

31 March 2020

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Interferon-beta increases systemic BAFF levels in multiple sclerosis without increasing autoantibody production

31 March 2020

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BAFF is elevated in serum of patients with Wegener's granulomatosis

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MS: is it one disease?

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B cell repertoire diversity and clonal expansion in multiple sclerosis brain lesions

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Spotlight on alemtuzumab.

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Isolated demyelinating syndromes: comparison of CSF oligoclonal bands and different MR imaging criteria to predict conversion to CDMS.

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Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.

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Identifiers

DOI

1 reference

Dimensions Publication ID

27 August 2017

1046075544

0 references

1 reference