(Q38056746)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23113570%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

title

Anti-tumour strategies aiming to target tumour-associated macrophages (English)

1 reference

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16 February 2020

1 reference

1

1 reference

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16 February 2020

author name string

Chunfen Mo

2

1 reference

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16 February 2020

Yongsheng Wang

3

1 reference

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16 February 2020

Dandan Wei

4

1 reference

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16 February 2020

Hengyi Xiao

5

1 reference

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16 February 2020

publication date

1 February 2013

1 reference

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16 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23113570%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

volume

138

1 reference

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16 February 2020

issue

2

1 reference

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16 February 2020

page(s)

93-104

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23113570%20AND%20SRC:MED&resulttype=core&format=json

Clinical and biological implications of the tumor microenvironment

16 February 2020

cites work

1 reference

Cancer-promoting tumor-associated macrophages: new vistas and open questions

21 January 2018

1 reference

Distinct role of macrophages in different tumor microenvironments

21 January 2018

1 reference

The inflammatory micro-environment in tumor progression: the role of tumor-associated macrophages

21 January 2018

1 reference

Altered macrophage differentiation and immune dysfunction in tumor development

21 January 2018

1 reference

Tumor-associated macrophages (TAM) as major players of the cancer-related inflammation

21 January 2018

1 reference

Plasticity of macrophage function during tumor progression: regulation by distinct molecular mechanisms

21 January 2018

1 reference

Macrophage diversity enhances tumor progression and metastasis

21 January 2018

1 reference

Macrophage polarization in tumour progression

21 January 2018

1 reference

Anti-PlGF inhibits growth of VEGF(R)-inhibitor-resistant tumors without affecting healthy vessels

21 January 2018

1 reference

Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects.

21 January 2018

1 reference

Radiotherapy decreases vascular density and causes hypoxia with macrophage aggregation in TRAMP-C1 prostate tumors

21 January 2018

1 reference

Blockade of tumor necrosis factor alpha signaling in tumor-associated macrophages as a radiosensitizing strategy

21 January 2018

1 reference

Inhibition of Mac-1 (CD11b/CD18) enhances tumor response to radiation by reducing myeloid cell recruitment

21 January 2018

1 reference

Tumor-associated macrophages and survival in classic Hodgkin's lymphoma

21 January 2018

1 reference

Analysis of multiple biomarkers shows that lymphoma-associated macrophage (LAM) content is an independent predictor of survival in follicular lymphoma (FL).

21 January 2018

1 reference

Tumor-associated macrophages as targets for tumor immunotherapy.

21 January 2018

1 reference

Blockade of a chemokine, CCL2, reduces chronic colitis-associated carcinogenesis in mice.

21 January 2018

1 reference

An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.

21 January 2018

1 reference

Targeting tumor-associated macrophages as a novel strategy against breast cancer

21 January 2018

1 reference

Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages

21 January 2018

1 reference

HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF

21 January 2018

1 reference

CCL2 and interleukin-6 promote survival of human CD11b+ peripheral blood mononuclear cells and induce M2-type macrophage polarization

21 January 2018

1 reference

The inflammatory chemokines CCL2 and CCL5 in breast cancer

21 January 2018

1 reference

Multiple roles of chemokine (C-C motif) ligand 2 in promoting prostate cancer growth.

21 January 2018

1 reference

Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

21 January 2018

1 reference

The chemokine CCL2 increases prostate tumor growth and bone metastasis through macrophage and osteoclast recruitment

21 January 2018

1 reference

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

21 January 2018

1 reference

Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy

21 January 2018

1 reference

Anti-inflammatory properties of the novel antitumor agent yondelis (trabectedin): inhibition of macrophage differentiation and cytokine production

21 January 2018

1 reference

Antitumor and anti-inflammatory effects of trabectedin on human myxoid liposarcoma cells.

21 January 2018

1 reference

Interleukin-6 as a therapeutic target in human ovarian cancer

21 January 2018

1 reference

An antimicrobial peptide regulates tumor-associated macrophage trafficking via the chemokine receptor CCR2, a model for tumorigenesis.

21 January 2018

1 reference

Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts

21 January 2018

1 reference

JNJ-28312141, a novel orally active colony-stimulating factor-1 receptor/FMS-related receptor tyrosine kinase-3 receptor tyrosine kinase inhibitor with potential utility in solid tumors, bone metastases, and acute myeloid leukemia.

21 January 2018

1 reference

M-CSF inhibition selectively targets pathological angiogenesis and lymphangiogenesis

21 January 2018

1 reference

Vascular endothelial growth factor receptor 2 mediates macrophage infiltration into orthotopic pancreatic tumors in mice.

21 January 2018

1 reference

Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.

21 January 2018

1 reference

TIE2-expressing macrophages limit the therapeutic efficacy of the vascular-disrupting agent combretastatin A4 phosphate in mice

21 January 2018

1 reference

Hypoxia-inducible factors 1 and 2 are important transcriptional effectors in primary macrophages experiencing hypoxia

21 January 2018

1 reference

HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion

21 January 2018

1 reference

Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation

21 January 2018

1 reference

Tumour macrophages as potential targets of bisphosphonates.

21 January 2018

1 reference

Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

21 January 2018

1 reference

Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages

21 January 2018

1 reference

Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma.

21 January 2018

1 reference

Zoledronic acid modulates antitumoral responses of prostate cancer-tumor associated macrophages.

21 January 2018

1 reference

Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma

21 January 2018

1 reference

Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.

21 January 2018

1 reference

The backbone of progress--preclinical studies and innovations with zoledronic acid

21 January 2018

1 reference

Endocrine therapy plus zoledronic acid in premenopausal breast cancer.

21 January 2018

1 reference

Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study.

21 January 2018

1 reference

Zoledronic acid use in cancer patients: more than just supportive care?

21 January 2018

1 reference

Rejection of intradermally injected syngeneic tumor cells from mice by specific elimination of tumor-associated macrophages with liposome-encapsulated dichloromethylene diphosphonate, followed by induction of CD11b(+)/CCR3(-)/Gr-1(-) cells cytotoxic

21 January 2018

1 reference

Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia

21 January 2018

1 reference

Antitumor activity of targeting SRC kinases in endothelial and myeloid cell compartments of the tumor microenvironment

21 January 2018

1 reference

Identifying alemtuzumab as an anti-myeloid cell antiangiogenic therapy for the treatment of ovarian cancer

21 January 2018

1 reference

Targeting tumor-associated macrophages in an experimental glioma model with a recombinant immunotoxin to folate receptor beta

21 January 2018

1 reference

Folate receptor beta is expressed by tumor-associated macrophages and constitutes a marker for M2 anti-inflammatory/regulatory macrophages

21 January 2018

1 reference

Clinical significance of folate receptor β-expressing tumor-associated macrophages in pancreatic cancer

21 January 2018

1 reference

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages

21 January 2018

1 reference

Shigella mediated depletion of macrophages in a murine breast cancer model is associated with tumor regression

21 January 2018

1 reference

A Legumain-based minigene vaccine targets the tumor stroma and suppresses breast cancer growth and angiogenesis

21 January 2018

1 reference

Anti-tumor potential of type-I NKT cells against CD1d-positive and CD1d-negative tumors in humans

21 January 2018

1 reference

Oncogene MYCN regulates localization of NKT cells to the site of disease in neuroblastoma

21 January 2018

1 reference

Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages

21 January 2018

1 reference

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

21 January 2018

1 reference

NF-κB as a central regulator of macrophage function in tumors.

21 January 2018

1 reference

TAMable tumor-associated macrophages in response to innate RNA sensing

21 January 2018

1 reference

Toll-like receptor 3 signaling converts tumor-supporting myeloid cells to tumoricidal effectors

21 January 2018

1 reference

Monophosphoryl Lipid A (MPL) as an Adjuvant for Anti-Cancer Vaccines: Clinical Results

21 January 2018

1 reference

Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells

21 January 2018

1 reference

TLR7 and TLR8 as targets in cancer therapy

21 January 2018

1 reference

Topical imidazoquinoline therapy of cutaneous squamous cell carcinoma polarizes lymphoid and monocyte/macrophage populations to a Th1 and M1 cytokine pattern

21 January 2018

1 reference

Reciprocal regulation of activating and inhibitory Fc{gamma} receptors by TLR7/8 activation: implications for tumor immunotherapy

21 January 2018

1 reference

A Toll-like receptor recognizes bacterial DNA

21 January 2018

1 reference

Therapeutic potential of Toll-like receptor 9 activation

21 January 2018

1 reference

Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides

21 January 2018

1 reference

Toll-like receptor 9 (TLR9) agonists in the treatment of cancer

21 January 2018

1 reference

Intracerebral administration of CpG oligonucleotide for patients with recurrent glioblastoma: a phase II study

21 January 2018

1 reference

Randomized phase 2/3 trial of CpG oligodeoxynucleotide PF-3512676 alone or with dacarbazine for patients with unresectable stage III and IV melanoma.

21 January 2018

1 reference

Phase I clinical trial of CpG oligonucleotide 7909 (PF-03512676) in patients with previously treated chronic lymphocytic leukemia

21 January 2018

1 reference

Targeting Toll-like receptors: emerging therapeutics?

21 January 2018

1 reference

CD40 ligation activates murine macrophages via an IFN-gamma-dependent mechanism resulting in tumor cell destruction in vitro

21 January 2018

1 reference

CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

21 January 2018

1 reference

Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects

21 January 2018

1 reference

"Re-educating" tumor-associated macrophages by targeting NF-kappaB.

21 January 2018

1 reference

TNF-α renders macrophages resistant to a range of cancer chemotherapeutic agents through NF-κB-mediated antagonism of apoptosis signalling.

21 January 2018

1 reference

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

21 January 2018

1 reference

NF-kappaB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1alpha

21 January 2018

1 reference

Interferons, immunity and cancer immunoediting

21 January 2018

1 reference

A critical function for type I interferons in cancer immunoediting

21 January 2018

1 reference

Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages

21 January 2018

1 reference

Nuclear factor-kappaB and tumor-associated macrophages

21 January 2018

1 reference

Stat1 deficiency in the host enhances interleukin-12-mediated tumor regression

21 January 2018

1 reference

Granulocyte macrophage colony-stimulating factor inhibits breast cancer growth and metastasis by invoking an anti-angiogenic program in tumor-educated macrophages

21 January 2018

1 reference

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

21 January 2018

1 reference

IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression

21 January 2018

1 reference

Rapid release of cytoplasmic IL-15 from tumor-associated macrophages is an initial and critical event in IL-12-initiated tumor regression

21 January 2018

1 reference

Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors.

21 January 2018

1 reference

Effect of thymosin alpha 1 on the antitumor activity of tumor-associated macrophage-derived dendritic cells

21 January 2018

1 reference

Activation of tumor-associated macrophages by thymosin alpha 1.

21 January 2018

1 reference

Antitumor activation of peritoneal macrophages by thymosin alpha-1.

21 January 2018

1 reference

A role for STAT3 and cathepsin S in IL-10 down-regulation of IFN-gamma-induced MHC class II molecule on primary human blood macrophages

21 January 2018

1 reference

STAT3 activation in macrophages following infection with Salmonella.

21 January 2018

1 reference

A critical role for Stat3 signaling in immune tolerance

21 January 2018

1 reference

A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients.

21 January 2018

1 reference

Sunitinib inhibition of Stat3 induces renal cell carcinoma tumor cell apoptosis and reduces immunosuppressive cells

21 January 2018

1 reference

The multikinase inhibitor sorafenib reverses the suppression of IL-12 and enhancement of IL-10 by PGE₂ in murine macrophages

21 January 2018

1 reference

Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages

21 January 2018

1 reference

Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors

21 January 2018

1 reference

Reduction of myeloid-derived suppressor cells and induction of M1 macrophages facilitate the rejection of established metastatic disease.

21 January 2018

1 reference

Alternative activation of macrophages by IL-4 requires SHIP degradation.

21 January 2018

1 reference

Krüppel-like factor 4 regulates macrophage polarization

21 January 2018

1 reference

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology.

21 January 2018

1 reference

PPARγ Activation Primes Human Monocytes into Alternative M2 Macrophages with Anti-inflammatory Properties

21 January 2018

1 reference

Macrophages, PPARs, and Cancer

21 January 2018

1 reference

Macrophage responses to hypoxia: implications for tumor progression and anti-cancer therapies

21 January 2018

1 reference

Macrophage expression of hypoxia-inducible factor-1 alpha suppresses T-cell function and promotes tumor progression

21 January 2018

1 reference

An ets2-driven transcriptional program in tumor-associated macrophages promotes tumor metastasis

21 January 2018

1 reference

Decoy receptor 3 enhances tumor progression via induction of tumor-associated macrophages

21 January 2018

1 reference

Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway

21 January 2018

1 reference

Genetic Deficiency in Plasma Protein HRG Enhances Tumor Growth and Metastasis by Exacerbating Immune Escape and Vessel Abnormalization

21 January 2018

1 reference

A novel copper chelate modulates tumor associated macrophages to promote anti-tumor response of T cells

21 January 2018

1 reference

Reprogramming of TAM toward proimmunogenic type through regulation of MAP kinases using a redox-active copper chelate

21 January 2018

1 reference

Activation of tumor-associated macrophages by the vascular disrupting agent 5,6-dimethylxanthenone-4-acetic acid induces an effective CD8+ T-cell-mediated antitumor immune response in murine models of lung cancer and mesothelioma

21 January 2018

1 reference

Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells

21 January 2018

1 reference

Growth inhibition and regression of lung tumors by silibinin: modulation of angiogenesis by macrophage-associated cytokines and nuclear factor-kappaB and signal transducers and activators of transcription 3.

21 January 2018

1 reference

Immunopotentiating effect of proton pump inhibitor pantoprazole in a lymphoma-bearing murine host: Implication in antitumor activation of tumor-associated macrophages

21 January 2018

1 reference

Cancer immunotherapy comes of age

21 January 2018

1 reference

Targeted delivery of oligonucleotides into tumor-associated macrophages for cancer immunotherapy

21 January 2018

1 reference

MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles

21 January 2018

1 reference

89Zr-labeled dextran nanoparticles allow in vivo macrophage imaging

21 January 2018

1 reference

Behavior of endogenous tumor-associated macrophages assessed in vivo using a functionalized nanoparticle.

21 January 2018

1 reference

Targeted imaging of tumor-associated M2 macrophages using a macromolecular contrast agent PG-Gd-NIR813.

21 January 2018

1 reference

The M1 form of tumor-associated macrophages in non-small cell lung cancer is positively associated with survival time

21 January 2018

1 reference

The number and microlocalization of tumor-associated immune cells are associated with patient's survival time in non-small cell lung cancer

21 January 2018

1 reference

Macrophage and mast-cell invasion of tumor cell islets confers a marked survival advantage in non-small-cell lung cancer.

21 January 2018

1 reference

CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3

21 January 2018

1 reference

TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growth

21 January 2018

1 reference

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

21 January 2018

1 reference

Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion

21 January 2018

1 reference

The diverse and complex roles of NF-κB subunits in cancer

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Oleanolic acid inhibits macrophage differentiation into the M2 phenotype and glioblastoma cell proliferation by suppressing the activation of STAT3.

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Role of tumour-associated macrophages in cancer-related inflammation

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells.

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Overexpression of legumain in tumors is significant for invasion/metastasis and a candidate enzymatic target for prodrug therapy.

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

Effect of thymosin-alpha1 on the production of nitric oxide by tumor-associated macrophages

5 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3575762

The presence of STAT1-positive tumor-associated macrophages and their relation to outcome in patients with follicular lymphoma

5 November 2018

1 reference

12 December 2020

IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo

1 reference

12 December 2020

High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma

1 reference

12 December 2020

Deficiency of the macrophage growth factor CSF-1 disrupts pancreatic neuroendocrine tumor development

1 reference

12 December 2020

Significance of M2-polarized tumor-associated macrophage in pancreatic cancer

1 reference

12 December 2020

Prognostic value of tumor-associated macrophage count in human bladder cancer

1 reference

12 December 2020

Scavenger receptor-A-targeted leukocyte depletion inhibits peritoneal ovarian tumor progression

1 reference

12 December 2020

Epigenetic control of MHC class II expression in tumor-associated macrophages by decoy receptor 3

1 reference

12 December 2020

Identifiers

DOI

10.1111/IMM.12023

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23113570%20AND%20SRC:MED&resulttype=core&format=json

16 February 2020

PMC publication ID

3575762

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23113570%20AND%20SRC:MED&resulttype=core&format=json