(Q38057775)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

title

Insulin-like growth factor-binding protein-6 and cancer (English)

1 reference

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17 February 2020

1

1 reference

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17 February 2020

author name string

Ping Fu

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

Zhiyong Yang

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

language of work or name

English

0 references

publication date

1 February 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

volume

124

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

page(s)

215-229

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth.

17 February 2020

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IGF-binding proteins--the pieces are falling into place.

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Insulin-like growth factors and neoplasia.

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Insulin-like growth factors control cell migration in health and disease

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21 January 2018

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21 January 2018

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O-glycosylation of insulin-like growth factor (IGF) binding protein-6 maintains high IGF-II binding affinity by decreasing binding to glycosaminoglycans and susceptibility to proteolysis

21 January 2018

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Binding characteristics of pro-insulin-like growth factor-II from cancer patients: binary and ternary complex formation with IGF binding proteins-1 to -6

21 January 2018

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Insulin-like growth factor binding protein-6: the "forgotten" binding protein?

21 January 2018

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The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A

21 January 2018

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Insulin-like growth factor (IGF) binding protein-3 attenuates prostate tumor growth by IGF-dependent and IGF-independent mechanisms.

21 January 2018

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Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence

21 January 2018

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Integrin-mediated action of insulin-like growth factor binding protein-2 in tumor cells

21 January 2018

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Insulin-like growth factor binding protein-2 binding to extracellular matrix plays a critical role in neuroblastoma cell proliferation, migration, and invasion

21 January 2018

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Identification of a novel cell death receptor mediating IGFBP-3-induced anti-tumor effects in breast and prostate cancer

21 January 2018

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Insights from insulin-like growth factor binding protein transgenic mice

21 January 2018

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Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5

21 January 2018

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Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice

21 January 2018

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Evidence of a role for insulin-like growth factor binding protein (IGFBP)-3 in metabolic regulation

21 January 2018

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IGFBP-3 is a metastasis suppression gene in prostate cancer

21 January 2018

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Insulin and insulin-like growth factor signalling in neoplasia

21 January 2018

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The IGF‐1 receptor in cancer biology

21 January 2018

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Modifying IGF1 activity: an approach to treat endocrine disorders, atherosclerosis and cancer

21 January 2018

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Hallmarks of Cancer: The Next Generation

21 January 2018

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Vascular endothelial growth factor and angiogenesis

21 January 2018

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Targeting the insulin-like growth factor axis for the development of novel therapeutics in oncology

21 January 2018

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Targeting the insulin-like growth factor pathway in rhabdomyosarcomas: rationale and future perspectives.

21 January 2018

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Structure of the IGF-binding domain of the insulin-like growth factor-binding protein-5 (IGFBP-5): implications for IGF and IGF-I receptor interactions

21 January 2018

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The N-terminal disulfide linkages of human insulin-like growth factor-binding protein-6 (hIGFBP-6) and hIGFBP-1 are different as determined by mass spectrometry

21 January 2018

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The N-terminal subdomain of insulin-like growth factor (IGF) binding protein 6. Structure and interaction with IGFs

21 January 2018

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Identification of O-glycosylation sites and partial characterization of carbohydrate structure and disulfide linkages of human insulin-like growth factor binding protein 6

21 January 2018

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Multiple post-translational modifications of mouse insulin-like growth factor binding protein-6 expressed in epithelial Madin-Darby canine kidney cells

21 January 2018

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Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.

21 January 2018

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C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II

21 January 2018

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Molecular and functional characterization of two distinct IGF binding protein-6 genes in zebrafish.

21 January 2018

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Dysregulation of energy homeostasis in mice overexpressing insulin-like growth factor-binding protein 6 in the brain

21 January 2018

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Expression of insulin-like growth factor system genes during the early postnatal neurogenesis in the mouse hippocampus

21 January 2018

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Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation

21 January 2018

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Microarray analysis of gene expression patterns in adult spinal motoneurons after different types of axonal injuries.

21 January 2018

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Insulin-like growth factor-binding protein 6 inhibits survival and differentiation of rat oligodendrocyte precursor cells

21 January 2018

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Myelin formation during development of the CNS is delayed in matrix metalloproteinase-9 and -12 null mice.

21 January 2018

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Inhibition of human osteoblast marker gene expression by retinoids is mediated in part by insulin-like growth factor binding protein-6.

21 January 2018

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Potential involvement of the interaction between insulin-like growth factor binding protein (IGFBP)-6 and LIM mineralization protein (LMP)-1 in regulating osteoblast differentiation

21 January 2018

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A functional nuclear localization signal in insulin-like growth factor binding protein-6 mediates its nuclear import

21 January 2018

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A novel interaction between insulin-like growth factor binding protein-6 and the vitamin D receptor inhibits the role of vitamin D3 in osteoblast differentiation

21 January 2018

1 reference

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Insulin-like growth factor binding protein-6 interacts with the thyroid hormone receptor α1 and modulates the thyroid hormone-response in osteoblastic differentiation

21 January 2018

1 reference

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Insulin-like growth factor binding protein-6 (IGFBP-6) interacts with DNA-end binding protein Ku80 to regulate cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

IGFBP-6 plays a role as an oncosuppressor gene in NPC pathogenesis through regulating EGR-1 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Rexinoid-induced expression of IGFBP-6 requires RARbeta-dependent permissive cooperation of retinoid receptors and AP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Identification of IGFBP-6 as a significantly downregulated gene by beta-catenin in desmoid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

TGF-beta modulates beta-Catenin stability and signaling in mesenchymal proliferations

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Gene expression profiling leads to identification of GLI1-binding elements in target genes and a role for multiple downstream pathways in GLI1-induced cell transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Sonic hedgehog signaling regulates the expression of insulin-like growth factor binding protein-6 during fetal prostate development

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Identification of Hedgehog signaling outcomes in mouse testis development using a hanging drop-culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Gli1 maintains cell survival by up-regulating IGFBP6 and Bcl-2 through promoter regions in parallel manner in pancreatic cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

IGF binding protein-6 expression in vascular endothelial cells is induced by hypoxia and plays a negative role in tumor angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

DNA microarrays identification of primary and secondary target genes regulated by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Expression profiling of p53-target genes in copper-mediated neuronal apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor binding proteins IGFBP3, IGFBP4, and IGFBP5 predict endocrine responsiveness in patients with ovarian cancer

21 January 2018

1 reference

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Insulin-like growth factor binding protein-6 inhibits prostate cancer cell proliferation: implication for anticancer effect of diethylstilbestrol in hormone refractory prostate cancer

21 January 2018

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Transcriptional activation of insulin-like growth factor binding protein 6 by 17beta-estradiol in SaOS-2 cells

21 January 2018

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Ethinylestradiol and testosterone have divergent effects on circulating IGF system components in adolescents with constitutional tall stature

21 January 2018

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Steroid-modulated proliferation of human endometrial carcinoma cell lines: any role for insulin-like growth factor signaling?

21 January 2018

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Progesterone and dexamethasone differentially regulate the IGF-system in glial cells.

21 January 2018

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Insulin-like growth factors and their binding proteins define specific phases of myometrial differentiation during pregnancy in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Cross-talk between MCP-3 and TGFbeta promotes fibroblast collagen biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Proteomic identification of insulin-like growth factor-binding protein-6 induced by sublethal H2O2 stress from human diploid fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor binding protein-6 delays replicative senescence of human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Matrix metalloproteinase-7 degrades all insulin-like growth factor binding proteins and facilitates insulin-like growth factor bioavailability

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Identification of candidate angiogenic inhibitors processed by matrix metalloproteinase 2 (MMP-2) in cell-based proteomic screens: disruption of vascular endothelial growth factor (VEGF)/heparin affin regulatory peptide (pleiotrophin) and VEGF/Conne

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Allelotype of pediatric rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Gene fusions involving PAX and FOX family members in alveolar rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Involvement of IGF-II in human cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor ligands, receptors, and binding proteins in cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

The IGFI receptor gene: a molecular target for disrupted transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Molecular pathogenesis of rhabdomyosarcoma

21 January 2018

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AP-2 may contribute to IGF-II overexpression in rhabdomyosarcoma

21 January 2018

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Patched target Igf2 is indispensable for the formation of medulloblastoma and rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Phosphoprotein pathway mapping: Akt/mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Molecular characterization of Patched-associated rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Sonic hedgehog and insulin-like growth factor signaling synergize to induce medulloblastoma formation from nestin-expressing neural progenitors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Betulinic acid induces apoptosis and inhibits hedgehog signalling in rhabdomyosarcoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor binding protein-6 and CCI-779, an ester analogue of rapamycin, additively inhibit rhabdomyosarcoma growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Cross-talk between MAP kinase pathways is involved in IGF-independent, IGFBP-6-induced Rh30 rhabdomyosarcoma cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

MAP kinases and cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Regulation of IGFBP6 gene and protein is mediated by the inverse expression and function of c-jun N-terminal kinase (JNK) and NFkappaB in a model of oral tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Targeted therapies of cancer: angiogenesis inhibition seems not enough

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Basic and therapeutic aspects of angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Tumor metastasis: molecular insights and evolving paradigms

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Activated Ras enhances insulin-like growth factor I induction of vascular endothelial growth factor in prostate epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Hypoxia-regulated angiogenic inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

The mechanisms of differential sensitivity to an insulin-like growth factor-1 receptor inhibitor (BMS-536924) and rationale for combining with EGFR/HER2 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Molecular cloning of IGFBP-5 from SCLC cell lines and expression of IGFBP-4, IGFBP-5 and IGFBP-6 in lung cancer cell lines and primary tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor binding protein-6 inhibits the growth of human bronchial epithelial cells and increases in abundance with all-trans-retinoic acid treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor binding protein-6 activates programmed cell death in non-small cell lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Regulation of insulin-like growth factor-binding-protein-1, 2, 3, 4, 5, and 6: synthesis, secretion, and gene expression in estrogen receptor-negative human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Identification of biomarkers modulated by the rexinoid LGD1069 (bexarotene) in human breast cells using oligonucleotide arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Differential expression of insulin-like growth factor binding proteins in high versus low Gleason score prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Expression of the IGF axis is decreased in local prostate cancer but enhanced after benign prostate epithelial differentiation and TGF-β treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

IGF-binding proteins in human prostate tumor cells: expression and regulation by 1,25-dihydroxyvitamin D3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Gene expression profiles in normal and cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Expression patterns of cell cycle and apoptosis-related genes in a multidrug-resistant human colon carcinoma cell line

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Inhibition of Caco-2 cell proliferation by all-trans retinoic acid: role of insulin-like growth factor binding protein-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Synthetic low-calcaemic vitamin D(3) analogues inhibit secretion of insulin-like growth factor II and stimulate production of insulin-like growth factor-binding protein-6 in conjunction with growth suppression of HT-29 colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Molecular determinants of terminal growth arrest induced in tumor cells by a chemotherapeutic agent

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced but not basal proliferation and adhesion of LIM 1215 colon cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Differential gene expression signature between primary and metastatic head and neck squamous cell carcinoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

High insulin-like growth factor-2 (IGF-2) gene expression is an independent predictor of poor survival for patients with advanced stage serous epithelial ovarian cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Targeting insulin and insulin-like growth factor pathways in epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Correlation analysis of HOX, ErbB and IGFBP family gene expression in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Deep depletion of abundant serum proteins reveals low-abundant proteins as potential biomarkers for human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

IGF-binding protein-6 is involved in growth inhibition in SH-SY5Y human neuroblastoma cells: its production is both IGF- and cell density-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Fibroblast growth factor-2 over-rides insulin-like growth factor-I induced proliferation and cell survival in human neuroblastoma cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

The IGF system in neuroblastoma xenografts: focus on IGF-binding protein-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Papillary and follicular thyroid carcinomas show distinctly different microarray expression profiles and can be distinguished by a minimum of five genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Expression profiling of adrenocortical neoplasms suggests a molecular signature of malignancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FCS20120343

21 January 2018

Identifiers

DOI

10.1042/CS20120343

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23126425%20AND%20SRC:MED&resulttype=core&format=json

17 February 2020

1 reference