(Q38059441)

28 August 2017

Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective (English)

1 reference

28 August 2017

Pseudomonas aeruginosa

0 references

0 references

7

Søren Molin

0 references

Helle Krogh Johansen

4

Helle Krogh Johansen

0 references

Niels Høiby

6

Niels Høiby

0 references

Oana Ciofu

5

Oana Ciofu

0 references

Lei Yang

Lei Yang

3

0 references

Anders Folkesson

Anders Folkesson

1

0 references

Lars Jelsbak

Lars Jelsbak

2

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language of work or name

English

0 references

publication date

13 November 2012

1 reference

Nature Reviews Microbiology

28 August 2017

1 reference

28 August 2017

10

1 reference

28 August 2017

12

1 reference

28 August 2017

841-851

1 reference

https://scigraph.springernature.com/pub.10.1038/nrmicro2907

28 August 2017

0 references

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Relationship of airway epithelial ion transport to chronic bronchitis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Lower respiratory infection and inflammation in infants with newly diagnosed cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Lower airway inflammation in infants with cystic fibrosis detected by newborn screening.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Eradication of early Pseudomonas aeruginosa infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa biofilms in the respiratory tract of cystic fibrosis patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Alveolar inflammation in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microbial ecology and adaptation in cystic fibrosis airways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Early aggressive eradication therapy for intermittent Pseudomonas aeruginosa airway colonization in cystic fibrosis patients: 15 years experience

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

CT of the paranasal sinuses is not a valid indicator for sinus surgery in CF patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microbial ecology of the cystic fibrosis lung

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Early infection and progression of cystic fibrosis lung disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Isolation measures for prevention of infection with respiratory pathogens in cystic fibrosis: a systematic review?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

The changing epidemiology of cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Longitudinal assessment of Pseudomonas aeruginosa in young children with cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Seasonal onset of initial colonisation and chronic infection with Pseudomonas aeruginosa in patients with cystic fibrosis in Denmark

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Eradication of Pseudomonas aeruginosa in cystic fibrosis patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Significant microbiological effect of inhaled tobramycin in young children with cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Genotypic characterization of Pseudomonas aeruginosa strains recovered from patients with cystic fibrosis after initial and subsequent colonization

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in lungs of cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Antibiotic therapy against Pseudomonas aeruginosa in cystic fibrosis: a European consensus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Early intervention and prevention of lung disease in cystic fibrosis: a European consensus

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Chronic inflammation in the cystic fibrosis lung: alterations in inter- and intracellular signaling

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Airway remodelling and its relationship to inflammation in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microarray analysis of the osmotic stress response in Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa biofilms exposed to imipenem exhibit changes in global gene expression and beta-lactamase and alginate production.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

MucA-mediated coordination of type III secretion and alginate synthesis in Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Parallel evolution in Pseudomonas aeruginosa over 39,000 generations in vivo.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Evolutionary dynamics of bacteria in a human host environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pulmonary oxidative stress response in young children with cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

The activity and hydrogen peroxide sensitivity of the peroxiredoxins from the parasitic nematode Haemonchus contortus.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Rethinking cystic fibrosis pathology: the critical role of abnormal reduced glutathione (GSH) transport caused by CFTR mutation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Antioxidant deficiency in cystic fibrosis: when is the right time to take action?

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Polymorphonuclear leucocytes consume oxygen in sputum from chronic Pseudomonas aeruginosa pneumonia in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Clinical significance of microbial infection and adaptation in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Antibody response to Pseudomonas aeruginosa in cystic fibrosis patients: a marker of therapeutic success?--A 30-year cohort study of survival in Danish CF patients after onset of chronic P. aeruginosa lung infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Identification of PSE and OXA beta-lactamase genes in Pseudomonas aeruginosa using PCR-restriction fragment length polymorphism

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Aminoglycoside-resistance mechanisms for cystic fibrosis Pseudomonas aeruginosa isolates are unchanged by long-term, intermittent, inhaled tobramycin treatment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Aminoglycoside resistance in Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

The bacterial glycocalyx in nature and disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Mucoid Pseudomonas aeruginosa resists nonopsonic phagocytosis by human neutrophils and macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Phagocytosis of mucoid and nonmucoid strains of Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Opsonization and phagocytosis of mucoid and non-mucoid Pseudomonas aeruginosa strains

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Scavenging by alginate of free radicals released by macrophages

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Identification of genes in the σ²² regulon of Pseudomonas aeruginosa required for cell envelope homeostasis in either the planktonic or the sessile mode of growth

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Conversion of Pseudomonas aeruginosa to mucoidy in cystic fibrosis: environmental stress and regulation of bacterial virulence by alternative sigma factors

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Genetic analysis of the alginate biosynthetic gene cluster of Pseudomonas aeruginosa shows evidence of an operonic structure.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Mucoid-to-nonmucoid conversion in alginate-producing Pseudomonas aeruginosa often results from spontaneous mutations in algT, encoding a putative alternate sigma factor, and shows evidence for autoregulation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Use of cell wall stress to characterize sigma 22 (AlgT/U) activation by regulated proteolysis and its regulon in Pseudomonas aeruginosa

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Cell wall-inhibitory antibiotics activate the alginate biosynthesis operon in Pseudomonas aeruginosa: Roles of sigma (AlgT) and the AlgW and Prc proteases

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Characterization of paired mucoid/non-mucoid Pseudomonas aeruginosa isolates from Danish cystic fibrosis patients: antibiotic resistance, beta-lactamase activity and RiboPrinting.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microbiology of airway disease in patients with cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Adaptive radiation in a heterogeneous environment

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa population diversity and turnover in cystic fibrosis chronic infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Evolution and diversification of Pseudomonas aeruginosa in the paranasal sinuses of cystic fibrosis children have implications for chronic lung infection

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

High frequency of hypermutable Pseudomonas aeruginosa in cystic fibrosis lung infection.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa biofilm infections in cystic fibrosis: insights into pathogenic processes and treatment strategies.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Colonisation and infection of the paranasal sinuses in cystic fibrosis patients is accompanied by a reduced PMN response.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Decreased mucosal oxygen tension in the maxillary sinuses in patients with cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Nasal and sinus disease in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Concordant genotype of upper and lower airways P aeruginosa and S aureus isolates in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Upper and lower airway cultures in children with cystic fibrosis: do not neglect the upper airways.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Social evolution theory for microorganisms.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa lasR mutants are associated with cystic fibrosis lung disease progression.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microevolution of the major common Pseudomonas aeruginosa clones C and PA14 in cystic fibrosis lungs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Historical contingency and the evolution of a key innovation in an experimental population of Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Darwinian evolution can follow only very few mutational paths to fitter proteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Second-order selection for evolvability in a large Escherichia coli population

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Epidemiology Of Chronic Pseudomonas aeruginosa Infections In Cystic Fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

In situ growth rates and biofilm development of Pseudomonas aeruginosa populations in chronic lung infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Parallel bacterial evolution within multiple patients identifies candidate pathogenicity genes.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosaMicroevolution during Cystic Fibrosis Lung Infection Establishes Clones with Adapted Virulence

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Dynamics of adaptive microevolution of hypermutable Pseudomonas aeruginosa during chronic pulmonary infection in patients with cystic fibrosis.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Adaptation of Pseudomonas aeruginosa during persistence in the cystic fibrosis lung

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Genome evolution and adaptation in a long-term experiment with Escherichia coli

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

The population genetics of ecological specialization in evolving Escherichia coli populations

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Understanding the evolutionary fate of finite populations: the dynamics of mutational effects

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Characterization of a Pseudomonas putida rough variant evolved in a mixed-species biofilm with Acinetobacter sp. strain C6.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Self-generated diversity produces "insurance effects" in biofilm communities

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Bacterial metapopulations in nanofabricated landscapes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Instantaneous within-patient diversity of Pseudomonas aeruginosa quorum-sensing populations from cystic fibrosis lung infections

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

The great leap forward. Major evolutionary jumps might be caused by changes in gene regulation rather than the emergence of new genes

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Divergence involving global regulatory gene mutations in an Escherichia coli population evolving under phosphate limitation

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microbial competition: Escherichia coli mutants that take over stationary phase cultures

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Microbial laboratory evolution in the era of genome-scale science

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Genome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Dissecting the genetic components of adaptation of Escherichia coli to the mouse gut.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Impact of large chromosomal inversions on the adaptation and evolution of Pseudomonas aeruginosa chronically colonizing cystic fibrosis lungs

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Pseudomonas aeruginosa Genomic Structure and Diversity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

New insights into bacterial adaptation through in vivo and in silico experimental evolution

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Spatial distribution of microbial communities in the cystic fibrosis lung

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Decade-long bacterial community dynamics in cystic fibrosis airways

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Relationship between cystic fibrosis respiratory tract bacterial communities and age, genotype, antibiotics and Pseudomonas aeruginosa.

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Targeted drug-aerosol delivery in the human respiratory system

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Respiratory tract colonization with Pseudomonas aeruginosa in cystic fibrosis: correlations between anti-Pseudomonas aeruginosa antibody levels and pulmonary function

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Analysis of promoters controlled by the putative sigma factor AlgU regulating conversion to mucoidy in Pseudomonas aeruginosa: relationship to sigma E and stress response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO2907

Mucoid Pseudomonas aeruginosa in cystic fibrosis: characterization of muc mutations in clinical isolates and analysis of clearance in a mouse model of respiratory infection

31 March 2020

1 reference

12 December 2020

Random amplified polymorphic DNA typing of Pseudomonas aeruginosa isolates recovered from patients with cystic fibrosis

1 reference

12 December 2020

Lung infection with alginate-producing, mucoid Pseudomonas aeruginosa in cystic fibrosis

1 reference

12 December 2020

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia

1 reference

12 December 2020

Pseudomonas aeruginosa alginate in cystic fibrosis sputum and the inflammatory response

1 reference

12 December 2020

Profiles of adaptation in two similar viruses

1 reference

12 December 2020

Early adaptive developments of Pseudomonas aeruginosa after the transition from life in the environment to persistent colonization in the airways of human cystic fibrosis hosts

1 reference

12 December 2020

Identifiers

DOI

10.1038/NRMICRO2907

1 reference

PubMed ID

23147702

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23147702