(Q38065991)

28 August 2017

1 reference

title

Agonist high- and low-affinity states of dopamine D₂ receptors: methods of detection and clinical implications (English)

1 reference

28 August 2017

author

Martin Christian Michel

5

object named as

Martin C Michel

1 reference

28 August 2017

author name string

Jan-Peter van Wieringen

1

1 reference

28 August 2017

Jan Booij

2

1 reference

28 August 2017

Vladimir Shalgunov

3

1 reference

28 August 2017

Philip Elsinga

4

1 reference

28 August 2017

publication date

9 December 2012

1 reference

Naunyn-Schmiedeberg's Archives of Pharmacology

28 August 2017

published in

1 reference

28 August 2017

volume

386

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28 August 2017

issue

2

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28 August 2017

page(s)

135-154

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Modulation of dopamine receptor agonist binding sites by cations and estradiol in intact pituitary and 7315a tumors

28 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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An animal model of genetic vulnerability to behavioral disinhibition and responsiveness to reward-related cues: implications for addiction.

21 January 2018

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Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

21 January 2018

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The functional state of the dopamine receptor in the anterior pituitary is in the high affinity form

21 January 2018

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Binding characteristics and sensitivity to endogenous dopamine of [11C]-(+)-PHNO, a new agonist radiotracer for imaging the high-affinity state of D2 receptors in vivo using positron emission tomography.

21 January 2018

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21 January 2018

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The dopamine D2 receptors in high-affinity state and D3 receptors in schizophrenia: a clinical [11C]-(+)-PHNO PET study

21 January 2018

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The effect of antipsychotics on the high-affinity state of D2 and D3 receptors: a positron emission tomography study With [11C]-(+)-PHNO.

21 January 2018

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[3H]-domperidone labels only a single population of receptors which convert from high to low affinity for dopamine in rat brain

21 January 2018

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Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907.

21 January 2018

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3H-dopamine binding to rat striatal D-2 and D-3 sites: enhancement by magnesium and inhibition by guanine nucleotides and sodium

21 January 2018

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Coupling mode of receptors and G proteins

21 January 2018

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Regulation of G protein-coupled receptor signalling: focus on the cardiovascular system and regulator of G protein signalling proteins

21 January 2018

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Dysfunctional brain networks and genetic risk for schizophrenia: specific neurotransmitter systems

21 January 2018

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The nature of dopamine dysfunction in schizophrenia and what this means for treatment

21 January 2018

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Quantitative determination of dopamine receptor subtypes not linked to activation of adenylate cyclase in rat striatum

21 January 2018

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The characterization of [3H]sulpiride binding sites in rat striatal membranes

21 January 2018

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21 January 2018

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21 January 2018

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Half a century of antipsychotics and still a central role for dopamine D2 receptors

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Human biodistribution and dosimetry of the D2/3 agonist 11C-N-propylnorapomorphine (11C-NPA) determined from PET.

21 January 2018

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Selective labelling of dopamine (D2) receptors in rat striatum by [3H]domperidone but not by [3H]spiperone

21 January 2018

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21 January 2018

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Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin

21 January 2018

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Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia

21 January 2018

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Increased brain dopamine and dopamine receptors in schizophrenia.

21 January 2018

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21 January 2018

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Dopamine D2 receptor radiotracers [(11)C](+)-PHNO and [(3)H]raclopride are indistinguishably inhibited by D2 agonists and antagonists ex vivo

21 January 2018

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Ex vivo [11C]-(+)-PHNO binding is unchanged in animal models displaying increased high-affinity states of the D2 receptor in vitro

21 January 2018

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Isoflurane anaesthesia differentially affects the amphetamine sensitivity of agonist and antagonist D2/D3 positron emission tomography radiotracers: implications for in vivo imaging of dopamine release

21 January 2018

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Spiperone: influence of spiro ring substituents on 5-HT2A serotonin receptor binding

21 January 2018

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Effects of antipsychotics on D3 receptors: a clinical PET study in first episode antipsychotic naive patients with schizophrenia using [11C]-(+)-PHNO.

21 January 2018

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Does antipsychotic withdrawal provoke psychosis? Review of the literature on rapid onset psychosis (supersensitivity psychosis) and withdrawal-related relapse

21 January 2018

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Psychosis associated to Parkinson's disease in the early stages: relevance of cognitive decline and depression

21 January 2018

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Measurement of the proportion of D2 receptors configured in state of high affinity for agonists in vivo: a positron emission tomography study using [11C]N-propyl-norapomorphine and [11C]raclopride in baboons

21 January 2018

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Dopamine (D2/3) receptor agonist positron emission tomography radiotracer [11C]-(+)-PHNO is a D3 receptor preferring agonist in vivo

21 January 2018

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A comparative evaluation of the dopamine D(2/3) agonist radiotracer [11C](-)-N-propyl-norapomorphine and antagonist [11C]raclopride to measure amphetamine-induced dopamine release in the human striatum

21 January 2018

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Imaging of dopamine D2/3 agonist binding in cocaine dependence: a [11C]NPA positron emission tomography study

21 January 2018

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Synthesis and dopamine receptor affinity of (R)-(-)-2-fluoro-N-n-propylnorapomorphine: a highly potent and selective dopamine D2 agonist

21 January 2018

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21 January 2018

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Exposure to nicotine produces an increase in dopamine D2(High) receptors: a possible mechanism for dopamine hypersensitivity

21 January 2018

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Ketamine/xylazine anesthesia alters [11C]MNPA binding to dopamine D2 receptors and response to methamphetamine challenge in monkey brain

21 January 2018

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Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain

21 January 2018

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D2 receptor occupancy in conscious rat brain is not significantly distinguished with [3H]-MNPA, [3H]-(+)-PHNO, and [3H]-raclopride

21 January 2018

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Kappa-opioid receptor stimulation quickens pathogenesis of compulsive checking in the quinpirole sensitization model of obsessive-compulsive disorder (OCD).

21 January 2018

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The dopamine D1-D2 receptor heteromer localizes in dynorphin/enkephalin neurons: increased high affinity state following amphetamine and in schizophrenia

21 January 2018

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Inactive-state preassembly of G(q)-coupled receptors and G(q) heterotrimers

21 January 2018

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Properties of D2 dopamine receptor autoradiography: high percentage of high-affinity agonist sites and increased nucleotide sensitivity in tissue sections

21 January 2018

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The neural basis of drug craving: an incentive-sensitization theory of addiction

21 January 2018

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"Breakthrough" dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time

21 January 2018

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Imaging dopamine D3 receptors in the human brain with positron emission tomography, [11C]PHNO, and a selective D3 receptor antagonist.

21 January 2018

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Dopamine D2(High) receptors on intact cells

21 January 2018

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Dopamine D2High receptors measured ex vivo are elevated in amphetamine-sensitized animals

21 January 2018

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All Roads to Schizophrenia Lead to Dopamine Supersensitivity and Elevated Dopamine D2High Receptors

21 January 2018

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Dopamine agonist radioligand binds to both D2High and D2Low receptors, explaining why alterations in D2High are not detected in human brain scans

21 January 2018

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Dopamine receptors in human and calf brains, using [3H]apomorphine and an antipsychotic drug

21 January 2018

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The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography

21 January 2018

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Dopamine displaces [3H]domperidone from high-affinity sites of the dopamine D2 receptor, but not [3H]raclopride or [3H]spiperone in isotonic medium: Implications for human positron emission tomography

21 January 2018

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Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis

21 January 2018

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Psychosis pathways converge via D2high dopamine receptors

21 January 2018

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Increased dopamine D2High receptors in knockouts of the dopamine transporter and the vesicular monoamine transporter may contribute to spontaneous hyperactivity and dopamine supersensitivity.

21 January 2018

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Increased dopamine D2(High) receptors in amphetamine-sensitized rats, measured by the agonist [(3)H](+)PHNO.

21 January 2018

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Glutamate receptor mGlu2 and mGlu3 knockout striata are dopamine supersensitive, with elevated D2(High) receptors and marked supersensitivity to the dopamine agonist (+)PHNO.

21 January 2018

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Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride

21 January 2018

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Within-subject comparison of [(11)C]-(+)-PHNO and [(11)C]raclopride sensitivity to acute amphetamine challenge in healthy humans

21 January 2018

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Repeated administration of a dopamine D1 receptor agonist reverses the increased proportions of striatal dopamine D1High and D2High receptors in methamphetamine-sensitized rats

21 January 2018

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Increase of dopamine D2(High) receptors in the striatum of rats sensitized to caffeine motor effects

21 January 2018

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Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors

21 January 2018

1 reference

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D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model

21 January 2018

1 reference

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Imaging the high-affinity state of the dopamine D2 receptor in vivo: fact or fiction?

21 January 2018

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3H-Dopamine binding sites differ in rat striatum and pituitary

21 January 2018

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Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptors

21 January 2018

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Increased proportion of high-affinity dopamine D2 receptors in rats with excitotoxic damage of the entorhinal cortex, an animal model of schizophrenia

21 January 2018

1 reference

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Precoupling of Gi/G(o)-linked receptors and its allosteric regulation by monovalent cations

21 January 2018

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Imaging dopamine receptors in humans with [11C]-(+)-PHNO: dissection of D3 signal and anatomy

21 January 2018

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Distinct functions of the two isoforms of dopamine D2 receptors

21 January 2018

1 reference

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The effects of kainic acid and 6-hydroxydopamine lesions, metal ions and GTP on in vitro binding of the D-2 dopamine agonist, [3H]N-0437, to striatal membranes

21 January 2018

1 reference

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Diagnostic value of asymmetric striatal D2 receptor upregulation in Parkinson's disease: an [123I]IBZM and [123I]FP-CIT SPECT study.

21 January 2018

1 reference

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Dopamine in drug abuse and addiction: results from imaging studies and treatment implications

21 January 2018

1 reference

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High-affinity states of human brain dopamine D2/3 receptors imaged by the agonist [11C]-(+)-PHNO.

21 January 2018

1 reference

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First human evidence of d-amphetamine induced displacement of a D2/3 agonist radioligand: A [11C]-(+)-PHNO positron emission tomography study

21 January 2018

1 reference

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Visual hallucinations in the diagnosis of idiopathic Parkinson's disease: a retrospective autopsy study

21 January 2018

1 reference

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Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation

21 January 2018

1 reference

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The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia.

21 January 2018

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Is alpha1D-adrenoceptor protein detectable in rat tissues?

21 January 2018

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Dopamine D2 densities and the schizophrenic brain.

21 January 2018

1 reference

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Dopamine D2 receptor dimers in human and rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00210-012-0817-0

Specific in vitro and in vivo binding of 3H-raclopride. A potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain

21 January 2018

2 references

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21 January 2018

12 December 2020

Differential regulation of the α2-adrenergic receptor by Na+ and guanine nucleotides

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Imaging dopamine transmission in schizophrenia. A review and meta-analysis.

21 January 2018

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12 December 2020

Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907)

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12 December 2020

Interactions of agonists with D-2 dopamine receptors: evidence for a single receptor population existing in multiple agonist affinity-states in rat striatal membranes

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12 December 2020

[3H]idazoxan and some other alpha 2-adrenergic drugs also bind with high affinity to a nonadrenergic site

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12 December 2020

Dopamine D2 receptor binding sites for agonists. A tetrahedral model

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12 December 2020

Correlation of alpha- and beta-rotameric forms of 2-substituted octahydrobenzo[f]quinoline dopamine congeners with high and low affinity states of the anterior pituitary dopamine receptor and prolactin inhibition.

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12 December 2020

The competition between endogenous dopamine and radioligands for specific binding to dopamine receptors

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12 December 2020

3H-Domperidone: A selective ligand for dopamine receptors

1 reference

12 December 2020

Anomalous properties of [3H]spiperone binding sites in various areas of the rat limbic system

1 reference

12 December 2020

Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding

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12 December 2020

Expression and pharmacological characterization of the human D3 dopamine receptor

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12 December 2020

Homology modeling of the dopamine D2 receptor and its testing by docking of agonists and tricyclic antagonists

1 reference

12 December 2020

The human dopamine D2(Longer) receptor has a high-affinity state and inhibits adenylyl cyclase

1 reference

12 December 2020

Elevated dopamine D2High receptors in alpha-1b-adrenoceptor knockout supersensitive mice

1 reference

12 December 2020

Dependence of dopamine receptor conversion from agonist high- to low-affinity state on temperature and sodium ions

1 reference

12 December 2020

SPECT imaging of striatal dopamine release after amphetamine challenge.

1 reference

12 December 2020

In vivo evidence for dopamine-mediated internalization of D2-receptors after amphetamine: differential findings with [3H]raclopride versus [3H]spiperone

1 reference

12 December 2020

Heterogenous binding of 3H-remoxipride to membranes of rat liver and brain

1 reference

12 December 2020

Dopamine receptor of the porcine anterior pituitary gland. Evidence for two affinity states discriminated by both agonists and antagonists

1 reference

12 December 2020

Characterization of [3H]quinpirole binding to human dopamine D2A and D3 receptors: effects of ions and guanine nucleotides

1 reference

12 December 2020

Dopamine agonist high-affinity state in solubilized D2 receptors in striatum, but not in anterior pituitary

1 reference

12 December 2020

Antischizophrenic drugs: chronic treatment elevates dopamine receptor binding in brain

1 reference

12 December 2020

Dopamine-deficient mice are hypersensitive to dopamine receptor agonists.

1 reference

12 December 2020

Agonist high- and low-affinity states of the D2-dopamine receptor in calf brain. Partial conversion by guanine nucleotide

1 reference

12 December 2020

Hyperactive mice show elevated D2(High) receptors, a model for schizophrenia: Calcium/calmodulin-dependent kinase II alpha knockouts

1 reference

12 December 2020

Interactions of agonists and antagonists with beta-adrenergic receptors on intact L6 muscle cells

1 reference

12 December 2020

Characterization of [3H]quinpirole binding to D2-like dopamine receptors in rat brain

1 reference

12 December 2020

Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2-adrenoceptor agonist high-affinity sites than [3H]rauwolscine? A comparison of nine tissues and cell lines

1 reference

12 December 2020

Anterior pituitary dopamine receptors. Demonstration of interconvertible high and low affinity states of the D-2 dopamine receptor

1 reference

12 December 2020

Sodium and guanine nucleotide regulation of dopamine receptor agonist and antagonist binding sites in MtTW15 pituitary tumors

1 reference

12 December 2020

Dopamine receptor binding on intact cells. Absence of a high-affinity agonist-receptor binding state

1 reference

12 December 2020

Regulation of ligand binding to pituitary D-2 dopaminergic receptors. Effects of divalent cations and functional group modification

1 reference

12 December 2020

Radioligand binding to beta adrenergic receptors of intact cultured S49 cells

1 reference

12 December 2020

II. Localization and characterization of dopamine D4 binding sites in rat and human brain by use of the novel, D4 receptor-selective ligand [3H]NGD 94-1.

1 reference

12 December 2020

Selectivity of (+)-4-propyl-9-hydroxynaphthoxazine [(+)-PHNO] for dopamine receptors in vitro and in vivo

1 reference

12 December 2020

Differential alpha1-adrenoceptor labeling by [3H]prazosin and [3H]tamsulosin

1 reference

12 December 2020

10.1007/S00210-012-0817-0

Identifiers

DOI

1 reference

Dimensions Publication ID

28 August 2017

1003942301

0 references

1 reference