(Q38066994)

28 August 2017

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title

Exploration of 4(1H)-pyridones as a novel family of potent antimalarial inhibitors of the plasmodial cytochrome bc1. (English)

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28 August 2017

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Iñigo Angulo-Barturen

3

object named as

Iñigo Angulo-Barturen

1 reference

28 August 2017

José M Bueno

1

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28 August 2017

Esperanza Herreros

2

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28 August 2017

Santiago Ferrer

4

1 reference

28 August 2017

José M Fiandor

5

1 reference

28 August 2017

Francisco J Gamo

6

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28 August 2017

Domingo Gargallo-Viola

7

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28 August 2017

Geo Derimanov

8

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28 August 2017

publication date

1 December 2012

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Future Medicinal Chemistry

28 August 2017

published in

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28 August 2017

volume

4

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28 August 2017

issue

18

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28 August 2017

page(s)

2311-2323

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The global portfolio of new antimalarial medicines under development.

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

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21 January 2018

1 reference

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Inhibitors of the mitochondrial electron transport chain and de novo pyrimidine biosynthesis as antimalarials: The present status

21 January 2018

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Mitochondrial drug targets in apicomplexan parasites.

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Genome sequence of the human malaria parasite Plasmodium falciparum

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Molecular basis for atovaquone binding to the cytochrome bc1 complex

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Atovaquone resistance in malaria parasites

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Malarone treatment failure and in vitro confirmation of resistance of Plasmodium falciparum isolate from Lagos, Nigeria

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

A chemical genomic analysis of decoquinate, a Plasmodium falciparum cytochrome b inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Optimization of endochin-like quinolones for antimalarial activity

21 January 2018

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HDQ, a potent inhibitor of Plasmodium falciparum proliferation, binds to the quinone reduction site of the cytochrome bc1 complex.

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria

21 January 2018

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Identification and validation of tetracyclic benzothiazepines as Plasmodium falciparum cytochrome bc1 inhibitors

21 January 2018

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Drug screen targeted at Plasmodium liver stages identifies a potent multistage antimalarial drug

21 January 2018

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Antimalarial activity of clopidol, 3,5-dichloro-2,6-dimethyl-4-pyridinol, and its esters, carbonates, and sulfonates

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Effects of decoquinate and clopidol on electron transport in mitochondria of Eimeria tenella (Apicomplexa: Coccidia).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Synthesis and anticoccidial activity of 3-fluoro-5-chloro- and -bromo-2,6-dimethyl-4-pyridinol

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Synthesis and structure-activity relationships of 4-pyridones as potential antimalarials

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

The effect of artemisinine, its derivatives and mefloquine against chloroquine-resistant strains of Plasmodium falciparum in vitro

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Preclinical drug metabolism and pharmacokinetic evaluation of GW844520, a novel anti-malarial mitochondrial electron transport inhibitor

21 January 2018

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Rapid method for the estimation of octanol/water partition coefficient (log P(oct)) from gradient RP-HPLC retention and a hydrogen bond acidity term (zetaalpha(2)(H)).

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

In vitro-in vivo correlations for lipophilic, poorly water-soluble drugs

21 January 2018

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https://api.crossref.org/works/10.4155%2FFMC.12.177

Circumventing the Crabtree Effect: Replacing Media Glucose with Galactose Increases Susceptibility of HepG2 Cells to Mitochondrial Toxicants

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Improved murine model of malaria using Plasmodium falciparum competent strains and non-myelodepleted NOD-scid IL2Rgammanull mice engrafted with human erythrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Nanosuspensions as particulate drug formulations in therapy. Rationale for development and what we can expect for the future.

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Fosamprenavir: advancing HIV protease inhibitor treatment options

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Preclinical pharmacology and pharmacokinetics of GW433908, a water-soluble prodrug of the human immunodeficiency virus protease inhibitor amprenavir

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

Inhibiting Plasmodium cytochrome bc1: a complex issue

21 January 2018

1 reference

https://api.crossref.org/works/10.4155%2FFMC.12.177

21 January 2018

Identifiers

DOI

10.4155/FMC.12.177

1 reference

release_kmimdjhmn5fflm3dxqvllt2buq

28 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/kmimdjhmn5fflm3dxqvllt2buq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference