(Q38068568)

28 August 2017

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title

Antibody-drug conjugates for the treatment of cancer (English)

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28 August 2017

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John A Flygare

1

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28 August 2017

Thomas H Pillow

series ordinal

2

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28 August 2017

Paul Aristoff

series ordinal

3

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28 August 2017

language of work or name

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1 January 2013

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Chemical Biology and Drug Design

28 August 2017

published in

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28 August 2017

volume

81

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28 August 2017

issue

1

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28 August 2017

page(s)

113-121

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

28 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Investigational antibody drug conjugates for solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Investigational antibody-drug conjugates for hematological malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-drug conjugates for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-drug conjugates - a perfect synergy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-drug conjugates: basic concepts, examples and future perspectives

21 January 2018

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https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-drug conjugates: linking cytotoxic payloads to monoclonal antibodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Arming antibodies for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Targeted cancer therapy: conferring specificity to cytotoxic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Guided molecular missiles for tumor-targeting chemotherapy--case studies using the second-generation taxoids as warheads.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Designing immunoconjugates for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Targeting of radio-isotopes for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Safety, pharmacokinetics, and preliminary clinical activity of inotuzumab ozogamicin, a novel immunoconjugate for the treatment of B-cell non-Hodgkin's lymphoma: results of a phase I study

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Gemtuzumab ozogamicin, a potent and selective anti-CD33 antibody-calicheamicin conjugate for treatment of acute myeloid leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Brentuximab Vedotin (SGN-35).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Structural characterization of the maytansinoid-monoclonal antibody immunoconjugate, huN901-DM1, by mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Design and application of antibody cysteine variants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Design, synthesis, and biological evaluation of antibody-drug conjugates comprised of potent camptothecin analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Monoclonal antibody conjugates of doxorubicin prepared with branched peptide linkers: inhibition of aggregation by methoxytriethyleneglycol chains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Structural modifications that alter the P-glycoprotein efflux properties of compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-maytansinoid conjugates are activated in targeted cancer cells by lysosomal degradation and linker-dependent intracellular processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

The effect of different linkers on target cell catabolism and pharmacokinetics/pharmacodynamics of trastuzumab maytansinoid conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Targeting of the CD33-calicheamicin immunoconjugate Mylotarg (CMA-676) in acute myeloid leukemia: in vivo and in vitro saturation and internalization by leukemic and normal myeloid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antibody-targeted chemotherapy with immunoconjugates of calicheamicin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Antitumor efficacy of a combination of CMC-544 (inotuzumab ozogamicin), a CD22-targeted cytotoxic immunoconjugate of calicheamicin, and rituximab against non-Hodgkin's B-cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

A calicheamicin conjugate with a fully humanized anti-MUC1 antibody shows potent antitumor effects in breast and ovarian tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Semisynthetic maytansine analogues for the targeted treatment of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Pharmacokinetics and biodistribution of the antitumor immunoconjugate, cantuzumab mertansine (huC242-DM1), and its two components in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Unraveling the role of proteases in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Protease-mediated fragmentation of p-amidobenzyl ethers: a new strategy for the activation of anticancer prodrugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

A self-immolative spacer that enables tunable controlled release of phenols under neutral conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Minor groove binder antibody conjugates employing a water soluble beta-glucuronide linker

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

The development of pyrrolobenzodiazepines as antitumour agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

DNA interstrand cross-linking and in vivo antitumor activity of the extended pyrrolo[2,1-c][1,4]benzodiazepine dimer SG2057.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Ribosomal biosynthesis of the cyclic peptide toxins of Amanita mushrooms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Therapeutic potential of amanitin-conjugated anti-epithelial cell adhesion molecule monoclonal antibody against pancreatic carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Selective formation of covalent protein heterodimers with an unnatural amino acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

Tumor-Specific Novel Taxoid−Monoclonal Antibody Conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FCBDD.12085

21 January 2018

Identifiers

DOI

10.1111/CBDD.12085

1 reference

28 August 2017

1 reference