(Q38070869)

28 August 2017

1 reference

title

Neurofilament phosphorylation and their proline-directed kinases in health and disease (English)

1 reference

28 August 2017

1 reference

Anne Holmgren

1

1 reference

PubMed ID

23279337

28 August 2017

Delphine Bouhy

series ordinal

2

1 reference

PubMed ID

23279337

28 August 2017

Vincent Timmerman

series ordinal

3

1 reference

28 August 2017

1 December 2012

1 reference

Journal of the Peripheral Nervous System

28 August 2017

1 reference

28 August 2017

17

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28 August 2017

4

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28 August 2017

365-376

1 reference

Glutamate slows axonal transport of neurofilaments in transfected neurons

28 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilament heavy chain side arm phosphorylation regulates axonal transport of neurofilaments.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The cell as a collection of protein machines: preparing the next generation of molecular biologists

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Assembly and exchange of intermediate filament proteins of neurons: neurofilaments are dynamic structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Interactions between peripherin and neurofilaments in cultured cells: disruption of peripherin assembly by the NF-M and NF-H subunits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilaments bind tubulin and modulate its polymerization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Axonal damage markers in cerebrospinal fluid are increased in ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The neurofilament heavy chain (NfH) in the cerebrospinal fluid diagnosis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Stochastic simulation of neurofilament transport in axons: the "stop-and-go" hypothesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Charcot-Marie-Tooth disease neurofilament mutations disrupt neurofilament assembly and axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Psychosine induces the dephosphorylation of neurofilaments by deregulation of PP1 and PP2A phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Mitogen-activated protein kinase regulates neurofilament axonal transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilaments can undergo axonal transport and cytoskeletal incorporation in a discontinuous manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Dynamics of mammalian high-molecular-weight neurofilament subunit phosphorylation in cultured rat sympathetic neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Molecular signaling how do axons die?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Defective axonal transport in a transgenic mouse model of amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

A dynamical system model of neurofilament transport in axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Myelin-associated glycoprotein modulates expression and phosphorylation of neuronal cytoskeletal elements and their associated kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Reversal of neuropathy phenotypes in conditional mouse model of Charcot-Marie-Tooth disease type 2E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Posttranslational modification of neurofilament polypeptides in rabbit retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Cross-linker system between neurofilaments, microtubules, and membranous organelles in frog axons revealed by the quick-freeze, deep-etching method

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Organization of mammalian neurofilament polypeptides within the neuronal cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Disruption of type IV intermediate filament network in mice lacking the neurofilament medium and heavy subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Mutations in the neurofilament light chain gene (NEFL) cause early onset severe Charcot-Marie-Tooth disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The high and middle molecular weight neurofilament subunits regulate the association of neurofilaments with kinesin: inhibition by phosphorylation of the high molecular weight subunit

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilaments are part of the high molecular weight complex containing neuronal cdc2-like kinase (nclk).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Multiple phosphorylated variants of the high molecular mass subunit of neurofilaments in axons of retinal cell neurons: characterization and evidence for their differential association with stationary and moving neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Activation of mitogen-activated protein kinases (Erk1 and Erk2) cascade results in phosphorylation of NF-M tail domains in transfected NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Integrins stimulate phosphorylation of neurofilament NF-M subunit KSP repeats through activation of extracellular regulated-kinases (Erk1/Erk2) in cultured motoneurons and transfected NIH 3T3 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilamentopathy in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Altered axonal architecture by removal of the heavily phosphorylated neurofilament tail domains strongly slows superoxide dismutase 1 mutant-mediated ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilament subunit NF-H modulates axonal diameter by selectively slowing neurofilament transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

A new variant of Charcot-Marie-Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

A novel CDK5-dependent pathway for regulating GSK3 activity and kinesin-driven motility in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Dynein mediates retrograde neurofilament transport within axons and anterograde delivery of NFs from perikarya into axons: regulation by multiple phosphorylation events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Deregulation of Cdk5 in a mouse model of ALS: toxicity alleviated by perikaryal neurofilament inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilament protein is phosphorylated in the squid giant axon

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

A critical step for JNK activation: isomerization by the prolyl isomerase Pin1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilament phosphoforms: surrogate markers for axonal injury, degeneration and loss

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilament-dependent radial growth of motor axons and axonal organization of neurofilaments does not require the neurofilament heavy subunit (NF-H) or its phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Gene replacement in mice reveals that the heavily phosphorylated tail of neurofilament heavy subunit does not affect axonal caliber or the transit of cargoes in slow axonal transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The neurofilament middle molecular mass subunit carboxyl-terminal tail domains is essential for the radial growth and cytoskeletal architecture of axons but not for regulating neurofilament transport rate

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Peptidyl-prolyl isomerase 1 regulates protein phosphatase 2A-mediated topographic phosphorylation of neurofilament proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Local control of neurofilament accumulation during radial growth of myelinating axons in vivo. Selective role of site-specific phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

In vivo and in vitro phosphorylation at Ser-493 in the glutamate (E)-segment of neurofilament-H subunit by glycogen synthase kinase 3beta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Phosphorylation of MEK1 by cdk5/p35 down-regulates the mitogen-activated protein kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Evidence that the monoclonal antibodies SMI-31 and SMI-34 recognize different phosphorylation-dependent epitopes of the murine high molecular mass neurofilament subunit.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Regulation of neurofilament dynamics by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Kinesin, dynein and neurofilament transport

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Occam's Razor slices through the mysteries of neurofilament axonal transport: can it really be so simple?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Does neurofilament phosphorylation regulate axonal transport?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Cyclin-dependent kinase 5 increases perikaryal neurofilament phosphorylation and inhibits neurofilament axonal transport in response to oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Cdk5 regulates axonal transport and phosphorylation of neurofilaments in cultured neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Muscle pathology without severe nerve pathology in a new mouse model of Charcot-Marie-Tooth disease type 2E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

cdc2-like kinase from rat spinal cord specifically phosphorylates KSPXK motifs in neurofilament proteins: isolation and characterization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Modulation of GSK-3-catalyzed phosphorylation of microtubule-associated protein tau by non-proline-dependent protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Monoclonal antibodies distinguish phosphorylated and nonphosphorylated forms of neurofilaments in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Kinesin accumulation in chick spinal axonal swellings with beta,beta'-iminodipropionitrile (IDPN) intoxication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Mitochondrial and axonal abnormalities precede disruption of the neurofilament network in a model of charcot-marie-tooth disease type 2E and are prevented by heat shock proteins in a mutant-specific fashion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neurofilaments switch between distinct mobile and stationary states during their transport along axons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Axonal neurofilaments differ in composition and morphology from those in the soma of the squid stellate ganglion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Cdk5 and MAPK are associated with complexes of cytoskeletal proteins in rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Declining phosphatases underlie aging-related hyperphosphorylation of neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The interaction of neurofilaments with the microtubule motor cytoplasmic dynein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Abnormal neurofilament transport caused by targeted disruption of neuronal kinesin heavy chain KIF5A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Neuronal intermediate filaments and ALS: a new look at an old question

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Selective accumulation of the high molecular weight neurofilament subunit within the distal region of growing axonal neurites

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Deleting the phosphorylated tail domain of the neurofilament heavy subunit does not alter neurofilament transport rate in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Alpha-internexin is structurally and functionally associated with the neurofilament triplet proteins in the mature CNS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Phosphorylation of the head domain of neurofilament protein (NF-M): a factor regulating topographic phosphorylation of NF-M tail domain KSP sites in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Increased expression of cdk5/p25 in N2a cells leads to hyperphosphorylation and impaired axonal transport of neurofilament proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Delayed maturation of regenerating myelinated axons in mice lacking neurofilaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

The novel neurofilament light (NEFL) mutation Glu397Lys is associated with a clinically and morphologically heterogeneous type of Charcot-Marie-Tooth neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

Deletions of the heavy neurofilament subunit tail in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1529-8027.2012.00434.X

10.1111/J.1529-8027.2012.00434.X

21 January 2018

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23279337