(Q47822839)

English

Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression.

scientific article published in June 2003

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Persistent activation of p38 mitogen-activated protein kinase in a mouse model of familial amyotrophic lateral sclerosis correlates with disease progression (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

amyotrophic lateral sclerosis

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Caterina Bendotti

8

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

Pietro Veglianese

2

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4 November 2019

author name string

M Tortarolo

1

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4 November 2019

N Calvaresi

3

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4 November 2019

A Botturi

4

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4 November 2019

C Rossi

5

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4 November 2019

A Giorgini

6

1 reference

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4 November 2019

A Migheli

7

1 reference

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4 November 2019

publication date

1 June 2003

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4 November 2019

Molecular and Cellular Neuroscience

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

23

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4 November 2019

2

1 reference

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4 November 2019

180-192

1 reference

Europe PubMed Central

PubMed publication ID

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4 November 2019

Glutamate slows axonal transport of neurofilaments in transfected neurons

1 reference

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7 January 2021

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Immune reactivity in a mouse model of familial ALS correlates with disease progression

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Cyclin dependent kinase-5 (CDK-5) phosphorylates neurofilament heavy (NF-H) chain to generate epitopes for antibodies that label neurofilament accumulations in amyotrophic lateral sclerosis (ALS) and is present in affected motor neurones in ALS

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

ALS, SOD and peroxynitrite

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity.

1 reference

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7 January 2021

based on heuristic

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Transgenic SOD1 G93A mice develop reduced GLT-1 in spinal cord without alterations in cerebrospinal fluid glutamate levels

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

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From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Blockade of p38 mitogen-activated protein kinase pathway inhibits inducible nitric-oxide synthase expression in mouse astrocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibitors of p38 mitogen-activated protein kinase promote neuronal survival in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyotrophic lateral sclerosis. unfolding the toxicity of the misfolded

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Minocycline slows disease progression in a mouse model of amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis induced by withdrawal of trophic factors is mediated by p38 mitogen-activated protein kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

p38 map kinase regulates TNF-alpha production in human astrocytes and microglia by multiple mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

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Inflammatory processes in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

JNK and p38 stresskinases--degenerative effectors of signal-transduction-cascades in the nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Ubiquitin and neurofilament expression in anterior horn cells in amyotrophic lateral sclerosis: possible clues to the pathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Lack of apoptosis in mice with ALS

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Axonal transport of neurofilaments in normal and disease states

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The p38 signal transduction pathway: activation and function

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutations in all five exons ofSOD-1 may cause ALS

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurotrophic molecules: strategies for designing effective therapeutic molecules in neurodegeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Minocycline, a tetracycline derivative, is neuroprotective against excitotoxicity by inhibiting activation and proliferation of microglia.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of nitric oxide in amyotrophic lateral sclerosis

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Minocycline delays disease onset and mortality in a transgenic model of ALS.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential expression of inflammation- and apoptosis-related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-7431%2803%2900022-8

7 January 2021

based on heuristic

inferred from DOI database lookup

Neurofilaments and orthograde transport are reduced in ventral root axons of transgenic mice that express human SOD1 with a G93A mutation

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Nitric oxide activation of poly(ADP-ribose) synthetase in neurotoxicity

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of p38 kinase links tau phosphorylation, oxidative stress, and cell cycle-related events in Alzheimer disease

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1044-7431(03)00022-8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

release_y77udvlvezeq5fkvldc4ovv3ai

1 reference

https://api.fatcat.wiki/v0/release/y77udvlvezeq5fkvldc4ovv3ai

24 November 2022

based on heuristic

mapped directly with Wikidata item

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12812752%20AND%20SRC:MED&resulttype=core&format=json

4 November 2019

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