(Q38074586)

28 August 2017

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title

Metabolism of inflammation limited by AMPK and pseudo-starvation (English)

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28 August 2017

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1

Luke A J O'Neill

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28 August 2017

D Grahame Hardie

2

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PubMed ID

23325217

28 August 2017

language of work or name

English

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publication date

1 January 2013

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28 August 2017

10

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inferred from page(s)

published in

Nature

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28 August 2017

493

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28 August 2017

7432

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28 August 2017

346-355

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https://scigraph.springernature.com/pub.10.1038/nature11862

28 August 2017

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Dimethylbiguanide inhibits cell respiration via an indirect effect targeted on the respiratory chain complex I.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11862

5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNATURE11862

Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Novel anti-inflammatory action of 5-aminoimidazole-4-carboxamide ribonucleoside with protective effect in dextran sulfate sodium-induced acute and chronic colitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

AMPK agonists ameliorate sodium and fluid transport and inflammation in cystic fibrosis airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

AICAR (5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside) increases the production of toxic molecules and affects the profile of cytokines release in LPS-stimulated rat primary microglial cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-activated protein kinase and inducible 6-phosphofructo-2-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

The ancient drug salicylate directly activates AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Short-term effects of daily aspirin on cancer incidence, mortality, and non-vascular death: analysis of the time course of risks and benefits in 51 randomised controlled trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Cancer risk associated with use of metformin and sulfonylurea in type 2 diabetes: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Insulin antagonizes ischemia-induced Thr172 phosphorylation of AMP-activated protein kinase alpha-subunits in heart via hierarchical phosphorylation of Ser485/491.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Inflammatory cytokines and hypoxia contribute to 18F-FDG uptake by cells involved in pannus formation in rheumatoid arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

Substrate fate in activated macrophages: a comparison between innate, classic, and alternative activation

21 January 2018

1 reference

12 December 2020

AMPKα1: a glucose sensor that controls CD8 T-cell memory

1 reference

12 December 2020

Dissecting regulatory networks by means of two-dimensional gel electrophoresis: application to the study of the diauxic shift in the yeast Saccharomyces cerevisiae

1 reference

12 December 2020

5'-AMP activates the AMP-activated protein kinase cascade, and Ca2+/calmodulin activates the calmodulin-dependent protein kinase I cascade, via three independent mechanisms

1 reference

12 December 2020

Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio

1 reference

12 December 2020

Respiration and glycolysis of normal human lymphocytes.

1 reference

12 December 2020

Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis

1 reference

12 December 2020

Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung

1 reference

12 December 2020

Yeast SNF1 is functionally related to mammalian AMP-activated protein kinase and regulates acetyl-CoA carboxylase in vivo.

1 reference

12 December 2020

An antibody VH domain with a lox-Cre site integrated into its coding region: bacterial recombination within a single polypeptide chain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE11862

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NATURE11862

1 reference

28 August 2017

1 reference

PubMed ID

23325217