(Q42924913)

11 November 2017

title

AMPK agonist downregulates innate and adaptive immune responses in TNBS-induced murine acute and relapsing colitis (English)

1 reference

11 November 2017

6

Qingdong Guan

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20797389

2 July 2024

author name string

Aiping Bai

1

1 reference

11 November 2017

Michael Yong

3

1 reference

11 November 2017

Yanbing Ma

5

1 reference

11 November 2017

Zhikang Peng

8

1 reference

11 November 2017

Allan G. Ma

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20797389

2 July 2024

Carolyn R. Weiss

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20797389

2 July 2024

Charles N. Bernstein

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20797389

2 July 2024

language of work or name

English

0 references

publication date

24 August 2010

1 reference

full work available at URL

11 November 2017

https://api.elsevier.com/content/article/PII:S0006295210006180?httpAccept=text/xml

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

https://api.elsevier.com/content/article/PII:S0006295210006180?httpAccept=text/plain

2 July 2024

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

2 July 2024

published in

Biochemical Pharmacology

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11 November 2017

volume

80

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11 November 2017

issue

11

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11 November 2017

page(s)

1708-1717

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Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes

11 November 2017

cites work

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Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid

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Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

2 July 2024

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The key role of macrophages in the immunopathogenesis of inflammatory bowel disease

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The interleukin-23 axis in intestinal inflammation

2 July 2024

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IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease

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Increased expression of interleukin 17 in inflammatory bowel disease

2 July 2024

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Both IL-12p70 and IL-23 are synthesized during active Crohn's disease and are down-regulated by treatment with anti-IL-12 p40 monoclonal antibody

2 July 2024

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Modulation of inflammatory response via alpha2-adrenoceptor blockade in acute murine colitis

2 July 2024

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Anti-interleukin-12 antibody for active Crohn's disease

2 July 2024

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Dietary histidine ameliorates murine colitis by inhibition of proinflammatory cytokine production from macrophages.

2 July 2024

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Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis

2 July 2024

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AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy

2 July 2024

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5-Aminoimidazole-4-carboxamide riboside sensitizes TRAIL- and TNF{alpha}-induced cytotoxicity in colon cancer cells through AMP-activated protein kinase signaling.

2 July 2024

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5-aminoimidazole-4-carboxamide ribonucleoside: a novel immunomodulator with therapeutic efficacy in experimental autoimmune encephalomyelitis.

2 July 2024

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Activation of AMPK attenuates neutrophil proinflammatory activity and decreases the severity of acute lung injury.

2 July 2024

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Five-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside attenuates poly (I:C)-induced airway inflammation in a murine model of asthma

2 July 2024

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A transient breach in the epithelial barrier leads to regulatory T-cell generation and resistance to experimental colitis

2 July 2024

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Critical role of IL-17 receptor signaling in acute TNBS-induced colitis

2 July 2024

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Regulation of gut inflammation and th17 cell response by interleukin-21.

2 July 2024

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The effect of the cholinergic anti-inflammatory pathway on experimental colitis

2 July 2024

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Porphyria cutanea tarda as a predictor of poor response to interferon alfa therapy in chronic hepatitis C.

2 July 2024

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Control of cytokine gene transcription in Th1 and Th2 cells.

2 July 2024

25

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The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease

2 July 2024

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The alternative NF-kappaB pathway from biochemistry to biology: pitfalls and promises for future drug development

2 July 2024

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LPS induction of gene expression in human monocytes

2 July 2024

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Nuclear factor kappaB is activated in macrophages and epithelial cells of inflamed intestinal mucosa

2 July 2024

29

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Macrophages derived from C3H/HeJ (Lpsd) mice respond to bacterial lipopolysaccharide by activating NF-kappa B.

2 July 2024

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NF-kappaB in inflammatory bowel disease

2 July 2024

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Adenosine 5'-monophosphate-activated protein kinase promotes macrophage polarization to an anti-inflammatory functional phenotype

2 July 2024

32

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

An interleukin 12 p40-IgG2b fusion protein abrogates T cell mediated inflammation: anti-inflammatory activity in Crohn's disease and experimental colitis in vivo

2 July 2024

33

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Regulation of T lymphocyte metabolism

2 July 2024

34

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Glucose metabolism in lymphocytes is a regulated process with significant effects on immune cell function and survival

2 July 2024

35

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

AMP-activated protein kinase, super metabolic regulator

2 July 2024

36

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Intravenous AICAR administration reduces hepatic glucose output and inhibits whole body lipolysis in type 2 diabetic patients

2 July 2024

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The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis

2 July 2024

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AMP-activated protein kinase as a drug target.

2 July 2024

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Activation of AMPK inhibits inflammation in MRL/lpr mouse mesangial cells

2 July 2024

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Activation of AMP kinase alpha1 subunit induces aortic vasorelaxation in mice

2 July 2024

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Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle.

2 July 2024

44

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Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 gene expression by 5-aminoimidazole-4-carboxamide riboside is independent of AMP-activated protein kinase

2 July 2024

45

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Blunting of AICAR-induced human skeletal muscle glucose uptake in type 2 diabetes is dependent on age rather than diabetic status

2 July 2024

46

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AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females

2 July 2024

47

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5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.

2 July 2024

48

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Biological therapy of inflammatory bowel disease

2 July 2024

49

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease

2 July 2024

50

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https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

Immunogenicity of infliximab: how to handle the problem?

2 July 2024

51

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

AMP-activated protein kinase regulates lymphocyte responses to metabolic stress but is largely dispensable for immune cell development and function

2 July 2024

52

1 reference

https://api.crossref.org/works/10.1016/J.BCP.2010.08.009

2 July 2024

Identifiers

1 reference

11 November 2017

1 reference