(Q38074601)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23325367%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Recent advances in the development of 1,8-naphthalimide based DNA targeting binders, anticancer and fluorescent cellular imaging agents (English)

1 reference

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22 February 2020

5

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22 February 2020

John M Kelly

8

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22 February 2020

Thorfinnur Gunnlaugsson

9

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22 February 2020

author name string

Swagata Banerjee

1

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22 February 2020

Emma B Veale

2

1 reference

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22 February 2020

Caroline M Phelan

3

1 reference

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22 February 2020

Samantha A Murphy

4

1 reference

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22 February 2020

Lisa J Gillespie

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23325367%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Daniel O Frimannsson

7

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22 February 2020

language of work or name

1 reference

17 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23325367%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

published in

Chemical Society Reviews

1 reference

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22 February 2020

volume

42

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22 February 2020

page(s)

1601-1618

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22 February 2020

issue

4

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Chemical approaches to the discovery and development of cancer therapies

22 February 2020

cites work

1 reference

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DNA and its associated processes as targets for cancer therapy

21 January 2018

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Naphthalimides as anti-cancer agents: synthesis and biological activity

21 January 2018

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Colorimetric and fluorescent anion sensors: an overview of recent developments in the use of 1,8-naphthalimide-based chemosensors

21 January 2018

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Anion recognition and sensing in organic and aqueous media using luminescent and colorimetric sensors

21 January 2018

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Demonstration of bidirectional photoinduced electron transfer (PET) sensing in 4-amino-1,8-naphthalimide based thiourea anion sensors.

21 January 2018

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Bidirectional photoinduced electron-transfer quenching is observed in 4-amino-1,8-naphthalimide-based fluorescent anion sensors

21 January 2018

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A synthetically simple, click-generated cyclam-based zinc(II) sensor

21 January 2018

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Cyclam-based "clickates": homogeneous and heterogeneous fluorescent sensors for Zn(II).

21 January 2018

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Colorimetric and ratiometric fluorescent chemosensor with a large red-shift in emission: Cu(II)-only sensing by deprotonation of secondary amines as receptor conjugated to naphthalimide fluorophore.

21 January 2018

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Zn2+-triggered amide tautomerization produces a highly Zn2+-selective, cell-permeable, and ratiometric fluorescent sensor.

21 January 2018

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Theoretical aspects of DNA-protein interactions: co-operative and non-co-operative binding of large ligands to a one-dimensional homogeneous lattice.

21 January 2018

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Derivatives of 4-amino-3,6-disulfonato-1,8-naphthalimide inhibit reverse transcriptase and suppress human and feline immunodeficiency virus expression in cultured cells

21 January 2018

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Inhibition of retrovirus-induced syncytium formation by photoproducts of a brominated 1,8-naphthalimide compound

21 January 2018

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Sequence-selective intercalation of antitumour bis-naphthalimides into DNA. Evidence for an approach via the major groove.

21 January 2018

1 reference

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Synthesis and mode(s) of action of a new series of imide derivatives of 3-nitro-1,8 naphthalic acid

21 January 2018

1 reference

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A novel histone deacetylase inhibitor, scriptaid, enhances expression of functional estrogen receptor alpha (ER) in ER negative human breast cancer cells in combination with 5-aza 2'-deoxycytidine.

21 January 2018

1 reference

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Intercalative binding to DNA of antitumour drugs derived from 3-nitro-1,8-naphthalic acid

21 January 2018

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N-(Aminoalkyl)imide antineoplastic agents. Synthesis and biological activity

21 January 2018

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Amino-substituted 2-[2'-(dimethylamino)ethyl]-1,2-dihydro-3H- dibenz[de,h]isoquinoline-1,3-diones. Synthesis, antitumor activity, and quantitative structure--activity relationship

21 January 2018

1 reference

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The bis(naphthalimide) DMP-840 causes cytotoxicity by its action against eukaryotic topoisomerase II.

21 January 2018

1 reference

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Solution structure and dynamics of a complex between DNA and the antitumor bisnaphthalimide LU-79553: intercalated ring flipping on the millisecond time scale

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Indirect effects modulating the interaction between DNA and a cytotoxic bisnaphthalimide reveal a two-step binding process.

21 January 2018

1 reference

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Synthesis, photophysical, and DNA binding studies of fluorescent Tröger's base derived 4-amino-1,8-naphthalimide supramolecular clefts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Napthalimidobenzamide DB-51630: a novel DNA binding agent inducing p300 gene expression and exerting a potent anti-cancer activity

21 January 2018

1 reference

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2,2,2-Trichloro-N-({2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinolin- 5-yl}carbamoyl)acetamide (UNBS3157), a novel nonhematotoxic naphthalimide derivative with potent antitumor activity

21 January 2018

1 reference

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5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior

21 January 2018

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Synthesis, cytotoxicity and apoptosis of naphthalimide polyamine conjugates as antitumor agents

21 January 2018

1 reference

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NPC-16, a novel naphthalimide-polyamine conjugate, induced apoptosis and autophagy in human hepatoma HepG2 cells and Bel-7402 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Bisnaphthalimidopropyl spermidine induces apoptosis within colon carcinoma cells

21 January 2018

1 reference

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Synthesis and biological activities of bisnaphthalimido polyamines derivatives: cytotoxicity, DNA binding, DNA damage and drug localization in breast cancer MCF 7 cells.

21 January 2018

1 reference

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A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis

21 January 2018

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A new synthetic agent with potent but selective cytotoxic activity against cancer

21 January 2018

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WMC-79, a potent agent against colon cancers, induces apoptosis through a p53-dependent pathway

21 January 2018

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Optimization of naphthalimide-imidazoacridone with potent antitumor activity leading to clinical candidate (HKH40A, RTA 502).

21 January 2018

1 reference

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Molecular recognition of DNA by rigid [N]-polynorbornane-derived bifunctional intercalators: synthesis and evaluation of their binding properties.

21 January 2018

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Novel naphthalimide-amino acid conjugates with flexible leucine moiety as side chain: design, synthesis and potential antitumor activity

21 January 2018

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New analogues of amonafide and elinafide, containing aromatic heterocycles: synthesis, antitumor activity, molecular modeling, and DNA binding properties.

21 January 2018

1 reference

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Chromophore-modified bisnaphthalimides: DNA recognition, topoisomerase inhibition, and cytotoxic properties of two mono- and bisfuronaphthalimides

21 January 2018

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Synthesis, antitumor activity, molecular modeling, and DNA binding properties of a new series of imidazonaphthalimides.

21 January 2018

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Molecular design, chemical synthesis, and biological evaluation of '4-1' pentacyclic aryl/heteroaryl-imidazonaphthalimides

21 January 2018

1 reference

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Synthesis, biological evaluation and DNA binding properties of novel mono and bisnaphthalimides.

21 January 2018

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DNA Sequence Recognition by Bispyrazinonaphthalimides Antitumor Agents

21 January 2018

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Alteration of the selectivity of DNA cleavage by a deglycobleomycin analogue containing a trithiazole moiety

21 January 2018

1 reference

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Photoactivated DNA cleavage by compounds structurally related to the bithiazole moiety of bleomycin

21 January 2018

1 reference

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Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains.

21 January 2018

1 reference

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B1-induced caspase-independent apoptosis in MCF-7 cells is mediated by down-regulation of Bcl-2 via p53 binding to P2 promoter TATA box.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

R16, a novel amonafide analogue, induces apoptosis and G2-M arrest via poisoning topoisomerase II.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Sulfur-substituted naphthalimides as photoactivatable anticancer agents: DNA interaction, fluorescence imaging, and phototoxic effects in cultured tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

N-aroyloxylthioxo-naphthalimides as DNA photocleavers of aroyloxyl oxygen radicals: synthesis, evaluation, and substituents' effect

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

The novel anti-tumor agents of 4-triazol-1,8-naphthalimides: synthesis, cytotoxicity, DNA intercalation and photocleavage

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide conjugates linked through piperazine side-armed alkane spacers

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Novel N-oxide of naphthalimides as prodrug leads against hypoxic solid tumor: synthesis and biological evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Novel aliphatic N-oxide of naphthalimides as fluorescent markers for hypoxic cells in solid tumor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

3-Nitro-naphthalimide and nitrogen mustard conjugate NNM-25 induces hepatocellular carcinoma apoptosis via PARP-1/p53 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Novel naphthalimide-benzoic acid conjugates as potential apoptosis-inducing agents: design, synthesis, and biological activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Synthesis of ODNs containing 4-methylamino-1,8-naphthalimide as a fluorescence probe in DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Charge separation and photosensitized damage in DNA mediated by naphthalimide, naphthaldiimide, and anthraquinone

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Consecutive adenine sequences are potential targets in photosensitized DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Cisplatin: from DNA damage to cancer chemotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Naphthalimide gold(I) phosphine complexes as anticancer metallodrugs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Photocytotoxic 3d-metal scorpionates with a 1,8-naphthalimide chromophore showing photoinduced DNA and protein cleavage activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Highly effective DNA photocleavage by novel "rigid" Ru(bpy)(3)-4-nitro- and -4-amino-1,8-naphthalimide conjugates

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Mechanisms of photoinitiated cleavage of DNA by 1,8-naphthalimide derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Synthesis and photophysical evaluation of a pyridinium 4-amino-1,8-naphthalimide derivative that upon intercalation displays preference for AT-rich double-stranded DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

Peptide bis-intercalator binds DNA via threading mode with sequence specific contacts in the major groove

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

A sequence-specific threading tetra-intercalator with an extremely slow dissociation rate constant

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

The synthesis and in vitro cytotoxic studies of novel bis-naphthalimidopropyl polyamine derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC2CS35467E

21 January 2018

Identifiers

DOI

10.1039/C2CS35467E

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23325367%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference