(Q38074721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

Endoglin for tumor imaging and targeted cancer therapy (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author

Lukas J.A.C. Hawinkels

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Madelon Paauwe

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Peter ten Dijke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

language of work or name

English

0 references

publication date

17 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

421-435

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23327677%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions

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Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells, leukemic cells, and syncytiotrophoblasts

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Molecular cloning and characterization of the human and porcine transforming growth factor-beta type III receptors

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Endoglin promotes endothelial cell proliferation and TGF-beta/ALK1 signal transduction

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Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily

21 January 2018

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Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth

21 January 2018

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Expression cloning and characterization of the TGF-beta type III receptor

21 January 2018

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Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system

21 January 2018

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BMP-9 signals via ALK1 and inhibits bFGF-induced endothelial cell proliferation and VEGF-stimulated angiogenesis

21 January 2018

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Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan.

21 January 2018

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Betaglycan presents ligand to the TGF beta signaling receptor.

21 January 2018

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Endoglin expression on human microvascular endothelial cells association with betaglycan and formation of higher order complexes with TGF-beta signalling receptors

21 January 2018

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Structural model of human endoglin, a transmembrane receptor responsible for hereditary hemorrhagic telangiectasia.

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Extracellular and cytoplasmic domains of endoglin interact with the transforming growth factor-beta receptors I and II

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ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration

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Endoglin expression is regulated by transcriptional cooperation between the hypoxia and transforming growth factor-beta pathways

21 January 2018

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Angiogenesis in breast cancer: the role of transforming growth factor beta and CD105.

21 January 2018

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Matrix metalloproteinase-14 (MT1-MMP)-mediated endoglin shedding inhibits tumor angiogenesis.

21 January 2018

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21 January 2018

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Endoglin is required for myogenic differentiation potential of neural crest stem cells

21 January 2018

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Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells

21 January 2018

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Endoglin: An accessory component of the TGF-beta-binding receptor-complex with diagnostic, prognostic, and bioimmunotherapeutic potential in human malignancies

21 January 2018

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CD105 protein depletion enhances human adipose-derived stromal cell osteogenesis through reduction of transforming growth factor β1 (TGF-β1) signaling

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Critical role of endoglin in tumor cell plasticity of Ewing sarcoma and melanoma

21 January 2018

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Expression and structural features of endoglin (CD105), a transforming growth factor beta1 and beta3 binding protein, in human melanoma

21 January 2018

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Endoglin inhibits prostate cancer motility via activation of the ALK2-Smad1 pathway

21 January 2018

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Defective angiogenesis in mice lacking endoglin

21 January 2018

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Endoglin, an ancillary TGFbeta receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

21 January 2018

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A murine model of hereditary hemorrhagic telangiectasia

21 January 2018

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Extracellular control of TGFbeta signalling in vascular development and disease

21 January 2018

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Endoglin-deficient mice, a unique model to study hereditary hemorrhagic telangiectasia

21 January 2018

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TGF-beta receptor function in the endothelium.

21 January 2018

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Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1.

21 January 2018

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Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

21 January 2018

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Pharmacological therapy of vascular malformations of the gastrointestinal tract

21 January 2018

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Estrogen therapy for hereditary haemorrhagic telangiectasia (HHT): Effects of raloxifene, on Endoglin and ALK1 expression in endothelial cells.

21 January 2018

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The logic of TGFbeta signaling.

21 January 2018

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Crosstalk between vascular endothelial growth factor, notch, and transforming growth factor-beta in vascular morphogenesis

21 January 2018

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Emerging role of bone morphogenetic proteins in angiogenesis

21 January 2018

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Endoglin mediates fibronectin/α5β1 integrin and TGF-β pathway crosstalk in endothelial cells

21 January 2018

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Activin receptor-like kinase (ALK)1 is an antagonistic mediator of lateral TGFbeta/ALK5 signaling

21 January 2018

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Balancing the activation state of the endothelium via two distinct TGF-beta type I receptors

21 January 2018

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Endoglin in angiogenesis and vascular diseases

21 January 2018

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Transforming growth factor-beta signaling through the Smad pathway: role in extracellular matrix gene expression and regulation

21 January 2018

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Reduced endoglin activity limits cardiac fibrosis and improves survival in heart failure

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Endoglin controls cell migration and composition of focal adhesions: function of the cytosolic domain

21 January 2018

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Endoglin regulates cytoskeletal organization through binding to ZRP-1, a member of the Lim family of proteins

21 January 2018

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The interaction of endoglin with beta-arrestin2 regulates transforming growth factor-beta-mediated ERK activation and migration in endothelial cells

21 January 2018

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CD105 prevents apoptosis in hypoxic endothelial cells

21 January 2018

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TGFbeta, cardiac fibroblasts, and the fibrotic response

21 January 2018

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Exploring anti-TGF-β therapies in cancer and fibrosis.

21 January 2018

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Role of endoglin in fibrosis and scleroderma

21 January 2018

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Endoglin expression regulates basal and TGF-beta1-induced extracellular matrix synthesis in cultured L6E9 myoblasts.

21 January 2018

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Role of tissue stroma in cancer cell invasion

21 January 2018

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Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts

21 January 2018

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Endoglin regulates cancer-stromal cell interactions in prostate tumors

21 January 2018

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Bevacizumab: overview of the literature

21 January 2018

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Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases

21 January 2018

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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer

21 January 2018

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Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

21 January 2018

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Long-term prognostic significance of neoangiogenesis in breast carcinomas: comparison of Tie-2/Tek, CD105, and CD31 immunocytochemical expression

21 January 2018

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Prognostic significance of carbonic anhydrase IX (CA-IX), endoglin (CD105) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) in breast cancer patients.

21 January 2018

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CD105 expression is an independent predictor of survival in patients with endometrial cancer

21 January 2018

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The prognostic value of endoglin (CD105) expression in ovarian carcinoma.

21 January 2018

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Correlation of matrix metalloproteinase suppressor genes RECK, VEGF, and CD105 with angiogenesis and biological behavior in esophageal squamous cell carcinoma

21 January 2018

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Prognostic relevance of CD105+ microvessel density in HNSCC patient outcome

21 January 2018

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Neoangiogenesis in laryngeal carcinoma: angiogenin and CD105 expression is related to carcinoma recurrence rate and disease-free survival.

21 January 2018

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Correlation between CD105 expression and postoperative recurrence and metastasis of hepatocellular carcinoma

21 January 2018

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Soluble endoglin and other circulating antiangiogenic factors in preeclampsia.

21 January 2018

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Plasma levels of soluble CD105 correlate with metastasis in patients with breast cancer

21 January 2018

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Circulating endothelial cells and angiogenic serum factors during neoadjuvant chemotherapy of primary breast cancer

21 January 2018

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Transforming growth factor-beta binding receptor endoglin (CD105) expression in esophageal cancer and in adjacent nontumorous esophagus as prognostic predictor of recurrence.

21 January 2018

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Endoglin (CD105) as a urinary and serum marker of prostate cancer

21 January 2018

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Tumor angiogenesis: tutorial on implications for imaging

21 January 2018

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Monitoring response to anticancer therapy by targeting microbubbles to tumor vasculature

21 January 2018

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Current limitations of molecular magnetic resonance imaging for tumors as evaluated with high-relaxivity CD105-specific iron oxide nanoparticles.

21 January 2018

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Perfusion of 99Tcm-labeled CD105 Mab into kidneys from patients with renal carcinoma suggests that CD105 is a promising vascular target.

21 January 2018

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In vivo targeting and positron emission tomography imaging of tumor vasculature with (66)Ga-labeled nano-graphene

21 January 2018

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Positron emission tomography and optical imaging of tumor CD105 expression with a dual-labeled monoclonal antibody.

21 January 2018

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DNA vaccines suppress tumor growth and metastases by the induction of anti-angiogenesis

21 January 2018

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Combination of low-dose cisplatin and recombinant xenogeneic endoglin as a vaccine induces synergistic antitumor activities.

21 January 2018

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Targeting tumor vasculature with novel Listeria-based vaccines directed against CD105.

21 January 2018

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Anti-endoglin monoclonal antibodies are effective for suppressing metastasis and the primary tumors by targeting tumor vasculature

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.758716

Anti-tumor activity of an anti-endoglin monoclonal antibody is enhanced in immunocompetent mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.758716

A phase I first-in-human study of TRC105 (Anti-Endoglin Antibody) in patients with advanced cancer

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.758716

Cancer-associated fibroblasts drive the progression of metastasis through both paracrine and mechanical pressure on cancer tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.758716