(Q38076754)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

review article

1 reference

title

The role of phosphatidylcholine and choline metabolites to cell proliferation and survival (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

author name string

Neale D Ridgway

series ordinal

1

1 reference

28 August 2017

language of work or name

1 reference

1 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

Critical Reviews in Biochemistry and Molecular Biology

22 February 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

volume

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

page(s)

20-38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23350810%20AND%20SRC:MED&resulttype=core&format=json

Enzymatic activity of the human 1-acylglycerol-3-phosphate-O-acyltransferase isoform 11: upregulated in breast and cervical cancers

22 February 2020

cites work

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Calcium-calmodulin kinase I cooperatively regulates nucleocytoplasmic shuttling of CCTα by accessing a nuclear export signal

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

14-3-3zeta escorts CCTalpha for calcium-activated nuclear import in lung epithelia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Modulation of cholinephosphotransferase activity in breast cancer cell lines by Ro5-4864, a peripheral benzodiazepine receptor agonist

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Perturbations of the AKT signaling pathway in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of phosphatidylcholine biosynthesis following induction of apoptosis in HL-60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Induction of choline kinase alpha by carbon tetrachloride (CCl4) occurs via increased binding of c-jun to an AP-1 element

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Structure and function of choline kinase isoforms in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Control of membrane phosphatidylcholine biosynthesis by diacylglycerol levels in neuronal cells undergoing neurite outgrowth.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Modulation of CTP:phosphocholine cytidylyltransferase by membrane curvature elastic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Apoptosis triggered by 1-O-octadecyl-2-O-methyl-rac-glycero-3-phosphocholine is prevented by increased expression of CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Oncogenic Ha-Ras transformation modulates the transcription of the CTP:phosphocholine cytidylyltransferase alpha gene via p42/44MAPK and transcription factor Sp3.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Sp-1 binds promoter elements that are regulated by retinoblastoma and regulate CTP:phosphocholine cytidylyltransferase-alpha transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phosphorylation of Sp1 by cyclin-dependent kinase 2 modulates the role of Sp1 in CTP:phosphocholine cytidylyltransferase alpha regulation during the S phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of phosphatidylcholine homeostasis by calcium-independent phospholipase A2.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

ATP citrate lyase is an important component of cell growth and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The identification of ATP-citrate lyase as a protein kinase B (Akt) substrate in primary adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Integration of metabolomics and expression of glycerol-3-phosphate acyltransferase (GPAM) in breast cancer-link to patient survival, hormone receptor status, and metabolic profiling

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

RNA interference-mediated silencing of the acetyl-CoA-carboxylase-alpha gene induces growth inhibition and apoptosis of prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The glucose dependence of Akt-transformed cells can be reversed by pharmacologic activation of fatty acid beta-oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Diacylglycerol kinases as sources of phosphatidic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Glycerophosphodiester phosphodiesterase domain containing 5 (GDPD5) expression correlates with malignant choline phospholipid metabolite profiles in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Integrin alpha6beta4 promotes expression of autotaxin/ENPP2 autocrine motility factor in breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Pyruvate kinase M2 is a phosphotyrosine-binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Translocation of CTP: phosphocholine cytidylyltransferase from cytosol to membranes in HeLa cells: stimulation by fatty acid, fatty alcohol, mono- and diacylglycerol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of CTP:phosphocholine cytidylyltransferase by amphitropism and relocalization

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phosphatidylcholine and cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of CTP: phosphocholine cytidylyltransferase activity by the physical properties of lipid membranes: an important role for stored curvature strain energy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The biology of cancer: metabolic reprogramming fuels cell growth and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Disruption of choline methyl group donation for phosphatidylethanolamine methylation in hepatocarcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Molecular distinction of phosphatidylcholine synthesis between the CDP-choline pathway and phosphatidylethanolamine methylation pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The intrinsically disordered nuclear localization signal and phosphorylation segments distinguish the membrane affinity of two cytidylyltransferase isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Secretory phospholipase A2-IIa is involved in prostate cancer progression and may potentially serve as a biomarker for prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Structure of the membrane binding domain of CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Akt stimulates aerobic glycolysis in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Identification of glycerol-3-phosphate acyltransferase as an adipocyte determination and differentiation factor 1- and sterol regulatory element-binding protein-responsive gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Interphase nuclei of many mammalian cell types contain deep, dynamic, tubular membrane-bound invaginations of the nuclear envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Involvement of raft aggregates enriched in Fas/CD95 death-inducing signaling complex in the antileukemic action of edelfosine in Jurkat cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

GDPD5 is a glycerophosphocholine phosphodiesterase that osmotically regulates the osmoprotective organic osmolyte GPC

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Differential role of human choline kinase alpha and beta enzymes in lipid metabolism: implications in cancer onset and treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Expansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Oxysterol activation of phosphatidylcholine synthesis involves CTP:phosphocholine cytidylyltransferase alpha translocation to the nuclear envelope.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

c-Ha-ras oncogene expression increases choline uptake, CTP: phosphocholine cytidylyltransferase activity and phosphatidylcholine biosynthesis in the immortalized human keratinocyte cell line HaCaT.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phosphatidylcholine biosynthesis in cultured glioma cells: evidence for channeling of intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Differential expression of cholinephosphotransferase in normal and cancerous human mammary epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Choline phospholipid metabolism in cancer: consequences for molecular pharmaceutical interventions.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Molecular causes of the aberrant choline phospholipid metabolism in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Transcription of the CTP:phosphocholine cytidylyltransferase alpha gene is enhanced during the S phase of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Balance of human choline kinase isoforms is critical for cell cycle regulation: implications for the development of choline kinase-targeted cancer therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Testis development, fertility, and survival in Ethanolamine kinase 2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

ATP citrate lyase inhibition can suppress tumor cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Proapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cloning and expression of a human choline/ethanolaminephosphotransferase: synthesis of phosphatidylcholine and phosphatidylethanolamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cloning, genomic organization, and characterization of a human cholinephosphotransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Tyrosine phosphorylation of mitochondrial pyruvate dehydrogenase kinase 1 is important for cancer metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Stereospecific chemoattraction of lymphoblastic cells by gradients of lysophosphatidylcholine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Sequential synthesis and methylation of phosphatidylethanolamine promote lipid droplet biosynthesis and stability in tissue culture and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Expression of Phosphatidylethanolamine N-Methyltransferase-2 Cannot Compensate for an Impaired CDP-choline Pathway in Mutant Chinese Hamster Ovary Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cancer cell metabolism: Warburg and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Alterations of choline phospholipid metabolism in ovarian tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Sterol-mediated regulation of human lipin 1 gene expression in hepatoblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cell cycle regulation of membrane phospholipid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Disruption of CCTbeta2 expression leads to gonadal dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Proton magnetic resonance spectroscopic imaging of human breast cancer: a preliminary study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Targeted deletion of hepatic CTP:phosphocholine cytidylyltransferase alpha in mice decreases plasma high density and very low density lipoproteins.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Hepatic CTP:phosphocholine cytidylyltransferase-alpha is a critical predictor of plasma high density lipoprotein and very low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Generation of phosphorylcholine as an essential event in the activation of Raf-1 and MAP-kinases in growth factors-induced mitogenic stimulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Conformation and lipid binding properties of four peptides derived from the membrane-binding domain of CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Molecular mechanisms involved in farnesol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Gene structure, expression and identification of a new CTP:phosphocholine cytidylyltransferase beta isoform.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Clinical utility of proton magnetic resonance spectroscopy in characterizing breast lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

I-PLA(2) activation during apoptosis promotes the exposure of membrane lysophosphatidylcholine leading to binding by natural immunoglobulin M antibodies and complement activation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Low-density lipoprotein-cholesterol/high-density lipoprotein-cholesterol ratio predicts lipid-rich coronary plaque in patients with coronary artery disease--integrated-backscatter intravascular ultrasound study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Molecular and functional characterization of choline transporter in human colon carcinoma HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The Akt-SREBP nexus: cell signaling meets lipid metabolism.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Fatty acid synthesis: a potential selective target for antineoplastic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The rate-limiting enzyme in phosphatidylcholine synthesis regulates proliferation of the nucleoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Partial characterization of a cDNA for human stearoyl-CoA desaturase and changes in its mRNA expression in some normal and malignant tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Phosphatidylcholine and choline homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Fatty acid synthase is a potential molecular target for the chemoprevention of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Distribution of CTP:phosphocholine cytidylyltransferase (CCT) isoforms. Identification of a new CCTbeta splice variant

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cloning and characterization of a second human CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Elevated phosphocholine concentration in ras-transformed NIH 3T3 cells arises from increased choline kinase activity, not from phosphatidylcholine breakdown

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Metabolic regulation by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The nucleoplasmic reticulum: form and function.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Lysophosphatidylcholine acyltransferase 1 (LPCAT1) overexpression in human colorectal cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Increased concentrations of phosphatidate, diacylglycerol and ceramide in ras- and tyrosine kinase (fps)-transformed fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Fatty acid synthase and the lipogenic phenotype in cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of fatty acid synthase (FAS) suppresses HER2/neu (erbB-2) oncogene overexpression in cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The emerging role of lysophosphatidic acid in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of stearoyl-CoA desaturase 1 expression induces CHOP-dependent cell death in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

A congenital muscular dystrophy with mitochondrial structural abnormalities caused by defective de novo phosphatidylcholine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

ET-18-OCH3 (edelfosine): a selective antitumour lipid targeting apoptosis through intracellular activation of Fas/CD95 death receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Ha-ras-transformation alters the metabolism of phosphatidylethanolamine and phosphatidylcholine in NIH 3T3 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Attraction of phagocytes by apoptotic cells is mediated by lysophosphatidylcholine.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Autotaxin as a novel serum marker of liver fibrosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Autotaxin (ATX), a potent tumor motogen, augments invasive and metastatic potential of ras-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Contribution of lipid second messengers to the regulation of phosphatidylcholine synthesis during cell cycle re-entry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Shuttling of CTP:Phosphocholine cytidylyltransferase between the nucleus and endoplasmic reticulum accompanies the wave of phosphatidylcholine synthesis during the G(0) --> G(1) transition

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

A novel glycerophosphodiester phosphodiesterase, GDE5, controls skeletal muscle development via a non-enzymatic mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Single nucleotide polymorphism of the human high affinity choline transporter alters transport rate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Induction of apoptosis using inhibitors of lysophosphatidic acid acyltransferase-beta and anti-CD20 monoclonal antibodies for treatment of human non-Hodgkin's lymphomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Migration to apoptotic "find-me" signals is mediated via the phagocyte receptor G2A.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Glycerolipid metabolism and signaling in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Apoptosis of insulin-secreting cells induced by endoplasmic reticulum stress is amplified by overexpression of group VIA calcium-independent phospholipase A2 (iPLA2 beta) and suppressed by inhibition of iPLA2 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Choline kinase activation is a critical requirement for the proliferation of primary human mammary epithelial cells and breast tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of choline kinase activity by Ras proteins involves Ral-GDS and PI3K

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Overexpression of choline kinase is a frequent feature in human tumor-derived cell lines and in lung, prostate, and colorectal human cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Transmembrane protein GDE2 induces motor neuron differentiation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Akt-Directed Glucose Metabolism Can Prevent Bax Conformation Change and Promote Growth Factor-Independent Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Early increase in choline kinase activity upon induction of the H-ras oncogene in mouse fibroblast cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation of the CDP-choline pathway by sterol regulatory element binding proteins involves transcriptional and post-transcriptional mechanisms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

1H HR-MAS and genomic analysis of human tumor biopsies discriminate between high and low grade astrocytomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Preferential induction of apoptosis of leukaemic cells by farnesol

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Metabolic profiling of human lung cancer tissue by 1H high resolution magic angle spinning (HRMAS) NMR spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Functional metabolic screen identifies 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 as an important regulator of prostate cancer cell survival.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

c-Jun N-terminal kinase regulates CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

High stearoyl-CoA desaturase protein and activity levels in simian virus 40 transformed-human lung fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Emerging roles for phospholipase A2 enzymes in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Recent progress on acyl CoA: lysophospholipid acyltransferase research

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

PLA2 activity is required for nuclear shrinkage in caspase-independent cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Autotaxin (lysoPLD/NPP2) protects fibroblasts from apoptosis through its enzymatic product, lysophosphatidic acid, utilizing albumin-bound substrate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Gliomas: histopathologic evaluation of changes in directionality and magnitude of water diffusion at diffusion-tensor MR imaging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Identification of transcriptional enhancer factor-4 as a transcriptional modulator of CTP:phosphocholine cytidylyltransferase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Sp1 is a co-activator with Ets-1, and Net is an important repressor of the transcription of CTP:phosphocholine cytidylyltransferase alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of Ca2+-independent phospholipase A2 decreases prostate cancer cell growth by p53-dependent and independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Quantification of choline- and ethanolamine-containing metabolites in human prostate tissues using 1H HR-MAS total correlation spectroscopy.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Increased lipogenesis in cancer cells: new players, novel targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Fatty acid synthase drives the synthesis of phospholipids partitioning into detergent-resistant membrane microdomains.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Contribution of each membrane binding domain of the CTP:phosphocholine cytidylyltransferase-alpha dimer to its activation, membrane binding, and membrane cross-bridging

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Lipid-Induced Conformational Switch in the Membrane Binding Domain of CTP:Phosphocholine Cytidylyltransferase: A Circular Dichroism Study

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The amphipathic helix of an enzyme that regulates phosphatidylcholine synthesis remodels membranes into highly curved nanotubules.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Autotaxin: a protein with two faces

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Expression of phosphatidylethanolamine N-methyltransferase in human hepatocellular carcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cytokine secretion requires phosphatidylcholine synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Identification of human plasma lysophospholipase D, a lysophosphatidic acid-producing enzyme, as autotaxin, a multifunctional phosphodiesterase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Mammalian diacylglycerol kinases: molecular interactions and biological functions of selected isoforms.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Cyclic phosphatidic acid is produced by autotaxin in blood

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Alkyl-lysophospholipid accumulates in lipid rafts and induces apoptosis via raft-dependent endocytosis and inhibition of phosphatidylcholine synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Inhibition of phosphatidylcholine synthesis is not the primary pathway in hexadecylphosphocholine-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Induction of CCAAT/enhancer-binding protein (C/EBP)-homologous protein/growth arrest and DNA damage-inducible protein 153 expression during inhibition of phosphatidylcholine synthesis is mediated via activation of a C/EBP-activating transcription fa

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Regulation and biological activities of the autotaxin-LPA axis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Hepatic phosphatidylethanolamine N-methyltransferase, unexpected roles in animal biochemistry and physiology

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The methylation of phosphatidylethanolamine

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Why has phosphatidylethanolamine N-methyltransferase survived in evolution?

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Blinded by the Light: The Growing Complexity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Farnesol inhibits phosphatidylcholine biosynthesis in cultured cells by decreasing cholinephosphotransferase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Why expression of phosphatidylethanolamine N-methyltransferase does not rescue Chinese hamster ovary cells that have an impaired CDP-choline pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Disruption of the murine gene encoding phosphatidylethanolamine N-methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Biochemical and evolutionary significance of phospholipid methylation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Early embryonic lethality in mice with targeted deletion of the CTP:phosphocholine cytidylyltransferase alpha gene (Pcyt1a)

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Identification of the nuclear localization signal of rat liver CTP:phosphocholine cytidylyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

21 January 2018

Biology of HIF-1alpha

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Glycerol-3-phosphate acyltransferases: rate limiting enzymes of triacylglycerol biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Evidence for phosphorylation of CTP:phosphocholine cytidylyltransferase by multiple proline-directed protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

"Laminopathies": a wide spectrum of human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Differential expression of choline kinase isoforms in skeletal muscle explains the phenotypic variability in the rostrocaudal muscular dystrophy mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Elevation of serum group II phospholipase A2 levels in patients with advanced cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Overexpression of group II phospholipase A2 in human breast cancer tissues is closely associated with their malignant potency

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Mammalian glycerophosphodiester phosphodiesterases

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The association of lipid activators with the amphipathic helical domain of CTP:phosphocholine cytidylyltransferase accelerates catalysis by increasing the affinity of the enzyme for CTP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Genomic organization, promoter activity, and expression of the human choline transporter-like protein 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Correlation of proton MR spectroscopic imaging with gleason score based on step-section pathologic analysis after radical prostatectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Nutritional genomics: defining the dietary requirement and effects of choline

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The increase of cell-membranous phosphatidylcholines containing polyunsaturated fatty acid residues induces phosphorylation of p53 through activation of ATR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Disruption of G1-phase phospholipid turnover by inhibition of Ca2+-independent phospholipase A2 induces a p53-dependent cell-cycle arrest in G1 phase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

GDE1/MIR16 is a glycerophosphoinositol phosphodiesterase regulated by stimulation of G protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

The expression level of lysophosphatidylcholine acyltransferase 1 (LPCAT1) correlates to the progression of prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643

Overexpression of PEMT2 downregulates the PI3K/Akt signaling pathway in rat hepatoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10409238.2012.735643