(Q38077517)

28 August 2017

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title

RKIP: much more than Raf kinase inhibitory protein (English)

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28 August 2017

Fahd Al-Mulla

1

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author name string

Milad S Bitar

series ordinal

2

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28 August 2017

Zainab Taqi

series ordinal

3

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28 August 2017

Kam C Yeung

series ordinal

4

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28 August 2017

publication date

1 August 2013

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Journal of Cellular Physiology

28 August 2017

published in

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28 August 2017

volume

228

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28 August 2017

issue

8

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28 August 2017

page(s)

1688-1702

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Chromosomal passengers and the (aurora) ABCs of mitosis

28 August 2017

cites work

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Wound hypoxia and acidosis limit neutrophil bacterial killing mechanisms.

21 January 2018

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Metastatic recurrence of early-stage colorectal cancer is linked to loss of heterozygosity on chromosomes 4 and 14q.

21 January 2018

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Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients.

21 January 2018

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Raf kinase inhibitor protein: mechanism of loss of expression and association with genomic instability.

21 January 2018

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Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3β.

21 January 2018

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RAF kinase inhibitory protein (RKIP) modulates cell cycle kinetics and motility

21 January 2018

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A new model for raf kinase inhibitory protein induced chemotherapeutic resistance

21 January 2018

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Regulation of MAPK/ERK signaling and photic entrainment of the suprachiasmatic nucleus circadian clock by Raf kinase inhibitor protein

21 January 2018

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The structure of Antirrhinum centroradialis protein (CEN) suggests a role as a kinase regulator

21 January 2018

1 reference

Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction

21 January 2018

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Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.

21 January 2018

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Inhibition of epithelial to mesenchymal transition in metastatic prostate cancer cells by the novel proteasome inhibitor, NPI-0052: pivotal roles of Snail repression and RKIP induction

21 January 2018

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Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP.

21 January 2018

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DNA hypermethylation in tumorigenesis: epigenetics joins genetics

21 January 2018

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Snail is a repressor of RKIP transcription in metastatic prostate cancer cells

21 January 2018

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Purification and characterization of a basic 23 kDa cytosolic protein from bovine brain.

21 January 2018

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Raf kinase inhibitor protein suppresses nuclear factor-κB-dependent cancer cell invasion through negative regulation of matrix metalloproteinase expression.

21 January 2018

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ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes

21 January 2018

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Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes

21 January 2018

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Localization of the novel neuropolypeptide h3 in subsets of tissues from different species

21 January 2018

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Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry

21 January 2018

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Novel therapeutic applications of nitric oxide donors in cancer: roles in chemo- and immunosensitization to apoptosis and inhibition of metastases.

21 January 2018

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A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins.

21 January 2018

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The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

21 January 2018

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RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis

21 January 2018

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Identification of RKIP as a differentially tyrosine-phosphorylated protein in nasopharyngeal carcinoma and normal nasopharyngeal epithelial tissues by phosphoproteomic approach

21 January 2018

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Possible role of RKIP in cytotrophoblast migration: immunohistochemical and in vitro studies

21 January 2018

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Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

21 January 2018

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Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7

21 January 2018

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Raf kinase inhibitor RKIP inhibits MDA-9/syntenin-mediated metastasis in melanoma

21 January 2018

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Raf kinase inhibitor protein (RKIP) dimer formation controls its target switch from Raf1 to G protein-coupled receptor kinase (GRK) 2.

21 January 2018

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A quantitative atlas of mitotic phosphorylation

21 January 2018

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Role of disorder in IκB-NFκB interaction

21 January 2018

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An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

21 January 2018

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Global identification of modular cullin-RING ligase substrates

21 January 2018

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Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

21 January 2018

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MAP kinase regulation of the mitotic spindle checkpoint

21 January 2018

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Raf kinase inhibitory protein regulates aurora B kinase and the spindle checkpoint

21 January 2018

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Glycogen synthase kinase-3 acts upstream of ADP-ribosylation factor 6 and Rac1 to regulate epithelial cell migration

21 January 2018

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Metastasis suppressor gene Raf kinase inhibitor protein (RKIP) is a novel prognostic marker in prostate cancer

21 January 2018

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Prognostic value of RKIP and p-ERK in gastric cancer

21 January 2018

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Targeting MET in cancer: rationale and progress

21 January 2018

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Proteomic analysis of low- to high-grade astrocytomas reveals an alteration of the expression level of raf kinase inhibitor protein and nucleophosmin.

21 January 2018

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The hippocampal cholinergic neurostimulating peptide, the N-terminal fragment of the secreted phosphatidylethanolamine-binding protein, possesses a new biological activity on cardiac physiology

21 January 2018

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Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor

21 January 2018

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Raf kinase inhibitory protein function is regulated via a flexible pocket and novel phosphorylation-dependent mechanism

21 January 2018

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Decreased expression and aberrant methylation of Raf kinase inhibitory protein gene in esophageal squamous cell carcinoma

21 January 2018

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Reduction of Raf-1 kinase inhibitor protein expression correlates with breast cancer metastasis

21 January 2018

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Raf kinase inhibitor protein regulation of raf and MAPK signaling

21 January 2018

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Secretome analysis of ionizing radiation-induced senescent cancer cells reveals that secreted RKIP plays a critical role in neighboring cell migration

21 January 2018

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Long-term ethanol exposure impairs neuronal differentiation of human neuroblastoma cells involving neurotrophin-mediated intracellular signaling and in particular protein kinase C.

21 January 2018

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Raf kinase inhibitor protein enhances neuronal differentiation in human SH-SY5Y cells

21 January 2018

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Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor.

21 January 2018

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Human liver protein map: a reference database established by microsequencing and gel comparison

21 January 2018

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Phospho-ERK staining is a poor indicator of the mutational status of BRAF and NRAS in human melanoma.

21 January 2018

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MicroRNA-224 targets RKIP to control cell invasion and expression of metastasis genes in human breast cancer cells

21 January 2018

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Expression of phosphorylated raf kinase inhibitor protein (pRKIP) is a predictor of lung cancer survival.

21 January 2018

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Cellular and molecular signal transduction pathways modulated by rituximab (rituxan, anti-CD20 mAb) in non-Hodgkin's lymphoma: implications in chemosensitization and therapeutic intervention

21 January 2018

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Inhibition of the Raf-MEK1/2-ERK1/2 signaling pathway, Bcl-xL down-regulation, and chemosensitization of non-Hodgkin's lymphoma B cells by Rituximab.

21 January 2018

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RKIP expression associated with gastric cancer cell invasion and metastasis

21 January 2018

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High levels of Nrf2 determine chemoresistance in type II endometrial cancer

21 January 2018

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Activation of NF-kappaB by Akt upregulates Snail expression and induces epithelium mesenchyme transition

21 January 2018

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A multigenic program mediating breast cancer metastasis to bone

21 January 2018

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NF-kappaB in cancer: from innocent bystander to major culprit

21 January 2018

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Raf kinase inhibitor protein: a prostate cancer metastasis suppressor gene

21 January 2018

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Loss of Raf-1 kinase inhibitory protein in pancreatic ductal adenocarcinoma.

21 January 2018

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Systematic and quantitative assessment of the ubiquitin-modified proteome

21 January 2018

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Expression of Raf-1 kinase inhibitory protein in carcinoma of the ampulla of Vater.

21 January 2018

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Reduced expression of Raf-1 kinase inhibitory protein predicts regional lymph node metastasis and shorter survival in esophageal squamous cell carcinoma

21 January 2018

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Raf-1 kinase inhibitory protein (RKIP) mediates ethanol-induced sensitization of secretagogue signaling in pancreatic acinar cells

21 January 2018

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EZH2 is a marker of aggressive breast cancer and promotes neoplastic transformation of breast epithelial cells

21 January 2018

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Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor

21 January 2018

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Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylation

21 January 2018

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Epigenetics and cancer treatment

21 January 2018

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Loss of Raf kinase inhibitor protein promotes cell proliferation and migration of human hepatoma cells

21 January 2018

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Effects of raf kinase inhibitor protein expression on metastasis and progression of human epithelial ovarian cancer

21 January 2018

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BRAF and RKIP aberrations in actinic keratosis and non-melanoma skin cancers.

21 January 2018

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The microenvironment of the tumour-host interface

21 January 2018

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Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

21 January 2018

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The microcosmos of cancer

21 January 2018

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Raf kinase inhibitor protein inhibits cell proliferation but promotes cell migration in rat hepatic stellate cells

21 January 2018

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Characterization of the protein ubiquitination response induced by Doxorubicin.

21 January 2018

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Additive effect on survival of Raf kinase inhibitor protein and signal transducer and activator of transcription 3 in high-grade glioma

21 January 2018

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The Polycomb complex PRC2 and its mark in life

21 January 2018

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Loss of RKIP expression during the carcinogenic evolution of endometrial cancer

21 January 2018

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Downregulation of RKIP is associated with poor outcome and malignant progression in gliomas

21 January 2018

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Raf family kinases: old dogs have learned new tricks

21 January 2018

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Identification of novel metastasis suppressor signaling pathways for breast cancer

21 January 2018

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Extensive DNA methylation in normal colorectal mucosa in hyperplastic polyposis.

21 January 2018

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Accumulation of hippocampal cholinergic neurostimulating peptide (HCNP)-related components in Hirano bodies

21 January 2018

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Possible implication of hippocampal cholinergic neurostimulating peptide (HCNP)-related components in Hirano body formation.

21 January 2018

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Regulation of RKIP function by Helicobacter pylori in gastric cancer

21 January 2018

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Mice lacking Raf kinase inhibitor protein-1 (RKIP-1) have altered sperm capacitation and reduced reproduction rates with a normal response to testicular injury.

21 January 2018

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Reduced expression of Raf-1 kinase inhibitory protein in renal cell carcinoma: a significant prognostic marker

21 January 2018

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Polycomb group protein-mediated repression of transcription

21 January 2018

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Plasticity demonstrated in the proteome of a parasitic nematode within the intestine of different host strains

21 January 2018

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Accumulation of the Raf-1 kinase inhibitory protein (Rkip) is associated with Cep290-mediated photoreceptor degeneration in ciliopathies

21 January 2018

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Metastasis: from dissemination to organ-specific colonization

21 January 2018

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Raf-1 kinase inhibitor protein: structure, function, regulation of cell signaling, and pivotal role in apoptosis

21 January 2018

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Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.

21 January 2018

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RKIP downregulates B-Raf kinase activity in melanoma cancer cells

21 January 2018

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Regulation of RKIP binding to the N-region of the Raf-1 kinase

21 January 2018

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Proteomic analysis reveals upregulation of RKIP in S-180 implanted BALB/C mouse after treatment with ascorbic acid

21 January 2018

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Sequence analysis of a mammalian phospholipid-binding protein from testis and epididymis and its distribution between spermatozoa and extracellular secretions

21 January 2018

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Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma

21 January 2018

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The Human Protein Atlas--a tool for pathology

21 January 2018

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The pathogenesis of cancer metastasis

21 January 2018

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G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

21 January 2018

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Expression and characterization of the PEBP homolog genes from Drosophila.

21 January 2018

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Glycogen synthase kinase 3: more than a namesake

21 January 2018

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Polycomb protein EZH2 regulates tumor invasion via the transcriptional repression of the metastasis suppressor RKIP in breast and prostate cancer

21 January 2018

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Unraveling the protective effect of a Drosophila phosphatidylethanolamine-binding protein upon bacterial infection by means of proteomics

21 January 2018

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The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling

21 January 2018

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Phosphatidylethanolamine binding protein is an abundant secretory product of haploid testicular germ cells in the rat.

21 January 2018

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Main structural and functional features of the basic cytosolic bovine 21 kDa protein delineated through hydrophobic cluster analysis and molecular modelling

21 January 2018

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Reduction in Raf kinase inhibitor protein expression is associated with increased Ras-extracellular signal-regulated kinase signaling in melanoma cell lines.

21 January 2018

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Global analysis of cellular protein translation by pulsed SILAC

21 January 2018

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Amino acid sequence of the Homo sapiens brain 21-23-kDa protein (neuropolypeptide h3), comparison with its counterparts from Rattus norvegicus and Bos taurus species, and expression of its mRNA in different tissues

21 January 2018

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Characterization and localization of the rat, mouse and human testicular phosphatidylethanolamine binding protein.

21 January 2018

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Widespread changes in protein synthesis induced by microRNAs

21 January 2018

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p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

21 January 2018

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Crystal structure of the phosphatidylethanolamine-binding protein from bovine brain: a novel structural class of phospholipid-binding proteins

21 January 2018

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Crystal structures of YBHB and YBCL from Escherichia coli, two bacterial homologues to a Raf kinase inhibitor protein

21 January 2018

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Unravelling the complexity of metastasis - molecular understanding and targeted therapies

21 January 2018

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Raf Kinase Inhibitory Protein protects cells against locostatin-mediated inhibition of migration

21 January 2018

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Characterization of the Raf kinase inhibitory protein (RKIP) binding pocket: NMR-based screening identifies small-molecule ligands

21 January 2018

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Didymin induces apoptosis by inhibiting N-Myc and upregulating RKIP in neuroblastoma

21 January 2018

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Nrf2 and Keap1 abnormalities in non-small cell lung carcinoma and association with clinicopathologic features

21 January 2018

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Reduced expression of Raf kinase inhibitor protein correlates with poor prognosis in pancreatic cancer.

21 January 2018

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A gene atlas of the mouse and human protein-encoding transcriptomes

21 January 2018

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RKIP inhibits NF-kappaB in cancer cells by regulating upstream signaling components of the IkappaB kinase complex

21 January 2018

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Ligand binding study of human PEBP1/RKIP: interaction with nucleotides and Raf-1 peptides evidenced by NMR and mass spectrometry

21 January 2018

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Raf kinase inhibitory protein knockout mice: expression in the brain and olfaction deficit

21 January 2018

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Alterations in the renal elastin-elastase system in type 1 diabetic nephropathy identified by proteomic analysis

21 January 2018

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Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation.

21 January 2018

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Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein

21 January 2018

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Raf kinase inhibitory protein regulates Raf-1 but not B-Raf kinase activation

21 January 2018

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MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta

21 January 2018

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Behaviour of bovine phosphatidylethanolamine-binding protein with model membranes. Evidence of affinity for negatively charged membranes

21 January 2018

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The polycomb group protein EZH2 is involved in progression of prostate cancer

21 January 2018

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

21 January 2018

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Role of Raf Kinase Inhibitor Protein in Hepatocellular Carcinoma

21 January 2018

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Loss of Raf kinase inhibitory protein induces radioresistance in prostate cancer

21 January 2018

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The activated NF-kappaB-Snail-RKIP circuitry in cancer regulates both the metastatic cascade and resistance to apoptosis by cytotoxic drugs

21 January 2018

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PEBP1 downregulation is associated to poor prognosis in HCC related to hepatitis B infection

21 January 2018

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Diabetic neuropathy and nerve regeneration

21 January 2018

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Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

21 January 2018

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Mechanism of suppression of the Raf/MEK/extracellular signal-regulated kinase pathway by the raf kinase inhibitor protein

21 January 2018

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Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation

21 January 2018

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Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer

21 January 2018

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BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma.

21 January 2018

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Frequent loss of RAF kinase inhibitor protein expression in acute myeloid leukemia

21 January 2018

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Transcriptional regulation of RKIP expression by androgen in prostate cells

21 January 2018

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RKIP inhibits the malignant phenotypes of gastric cancer cells

21 January 2018

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A chemical inhibitor reveals the role of Raf kinase inhibitor protein in cell migration.

21 January 2018

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Two-marker protein profile predicts poor prognosis in patients with early rectal cancer

21 January 2018

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Comprehensive analysis of CpG island methylator phenotype (CIMP)-high, -low, and -negative colorectal cancers based on protein marker expression and molecular features.

21 January 2018

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Novel Flavonoid Didymin Inhibits Neuroblastomas--Letter

21 January 2018

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RKIP and cellular motility

21 January 2018

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Genetic profiling of stage I and II colorectal cancer may predict metastatic relapse

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24335

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28 August 2017

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