(Q38079295)

28 August 2017

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title

Neural stem cell-based treatment for neurodegenerative diseases (English)

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28 August 2017

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Seung U Kim

1

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28 August 2017

Hong J Lee

series ordinal

2

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28 August 2017

Yun B Kim

series ordinal

3

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28 August 2017

publication date

5 February 2013

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28 August 2017

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28 August 2017

volume

33

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28 August 2017

issue

5

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28 August 2017

page(s)

491-504

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Embryonic stem cell lines derived from human blastocysts

28 August 2017

cites work

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Brain transplantation of immortalized human neural stem cells promotes functional recovery in mouse intracerebral hemorrhage stroke model

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Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons.

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Enhanced in vitro midbrain dopamine neuron differentiation, dopaminergic function, neurite outgrowth, and 1-methyl-4-phenylpyridium resistance in mouse embryonic stem cells overexpressing Bcl-XL.

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Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity.

21 January 2018

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Dopaminergic neurons generated from monkey embryonic stem cells function in a Parkinson primate model.

21 January 2018

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Behavioral improvement in a primate Parkinson's model is associated with multiple homeostatic effects of human neural stem cells.

21 January 2018

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Production and characterization of immortal human neural stem cell line with multipotent differentiation property

21 January 2018

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Transplantation of human neural stem cells exerts neuroprotection in a rat model of Parkinson's disease.

21 January 2018

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Grafting fibroblasts genetically modified to produce L-dopa in a rat model of Parkinson disease

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Survival and function of intrastriatally grafted primary fibroblasts genetically modified to produce l-dopa

21 January 2018

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Long-term correction of rat model of Parkinson's disease by gene therapy

21 January 2018

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Brain transplantation of neural stem cells cotransduced with tyrosine hydroxylase and GTP cyclohydrolase 1 in Parkinsonian rats

21 January 2018

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Brain transplantation of human neural stem cells transduced with tyrosine hydroxylase and GTP cyclohydrolase 1 provides functional improvement in animal models of Parkinson disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Highly efficient and large-scale generation of functional dopamine neurons from human embryonic stem cells.

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

ES cell-derived renewable and functional midbrain dopaminergic progenitors.

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Identification of embryonic stem cell-derived midbrain dopaminergic neurons for engraftment

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Protein-based human iPS cells efficiently generate functional dopamine neurons and can treat a rat model of Parkinson disease

21 January 2018

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Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats

21 January 2018

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Derivation of dopaminergic neurons from pluripotent stem cells

21 January 2018

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Motor and cognitive improvements in patients with Huntington's disease after neural transplantation

21 January 2018

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Fetal tissue transplants in animal models of Huntington's disease: the effects on damaged neuronal circuitry and behavioral deficits

21 January 2018

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Striatal transplantation in a transgenic mouse model of Huntington's disease

21 January 2018

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Transplanted fetal striatum in Huntington's disease: phenotypic development and lack of pathology

21 January 2018

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A patient with Huntington's disease and long-surviving fetal neural transplants that developed mass lesions

21 January 2018

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Cell replacement therapies for central nervous system disorders.

21 January 2018

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

21 January 2018

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Reduced basal ganglia blood flow and volume in pre-symptomatic, gene-tested persons at-risk for Huntington's disease

21 January 2018

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The distribution of structural neuropathology in pre-clinical Huntington's disease

21 January 2018

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Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Excitotoxic injury of the neostriatum: a model for Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Grafts of EGF-responsive neural stem cells derived from GFAP-hNGF transgenic mice: trophic and tropic effects in a rodent model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cell transplants improve motor function in a rat model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Neural progenitor implantation restores metabolic deficits in the brain following striatal quinolinic acid lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Intravenous administration of human neural stem cells induces functional recovery in Huntington's disease rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Preservation of striatal tissue and behavioral function after neural stem cell transplantation in a rat model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

3-Nitropropionate, the toxic substance of Indigofera , is a suicide inactivator of succinate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Brain-derived neurotrophic factor-mediated protection of striatal neurons in an excitotoxic rat model of Huntington's disease, as demonstrated by adenoviral gene transfer

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4/5 prevent the death of striatal projection neurons in a rodent model of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Slowed progression in models of Huntington disease by adipose stem cell transplantation

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Implantation of undifferentiated and pre-differentiated human neural stem cells in the R6/2 transgenic mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human embryonic stem cell-derived neural precursor transplants attenuate apomorphine-induced rotational behavior in rats with unilateral quinolinic acid lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Striatal progenitors derived from human ES cells mature into DARPP32 neurons in vitro and in quinolinic acid-lesioned rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Comparison of transplant efficiency between spontaneously derived and noggin-primed human embryonic stem cell neural precursors in the quinolinic acid rat model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Stem cell-based cell therapy for Huntington disease: a review

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Amyotrophic lateral sclerosis

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

ALS: a disease of motor neurons and their nonneuronal neighbors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Directed differentiation of embryonic stem cells into motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Axonal growth of embryonic stem cell-derived motoneurons in vitro and in motoneuron-injured adult rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Functional properties of motoneurons derived from mouse embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Fate of immortalized human neuronal progenitor cells transplanted in rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cell grafts ameliorate motor neuron disease in SOD-1 transgenic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cell replacement therapy for amyotrophic lateral sclerosis by spinal transplantation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: results of a phase I trial in 12 patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Distribution, differentiation, and survival of intravenously administered neural stem cells in a rat model of amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Stem cells for the treatment of neurological disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

GDNF delivery using human neural progenitor cells in a rat model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

VEGF delivery with retrogradely transported lentivector prolongs survival in a mouse ALS model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Vascular endothelial growth factor prolongs survival in a transgenic mouse model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Treatment of motoneuron degeneration by intracerebroventricular delivery of VEGF in a rat model of ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Intrathecal transplantation of human neural stem cells overexpressing VEGF provide behavioral improvement, disease onset delay and survival extension in transgenic ALS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

The cholinergic hypothesis of geriatric memory dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Cholinergic dysfunction in a mouse model of Alzheimer disease is reversed by an anti-A beta antibody

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

Metabolic regulation of brain Abeta by neprilysin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Reducing amyloid plaque burden via ex vivo gene delivery of an Abeta-degrading protease: a novel therapeutic approach to Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Implants of polymer-encapsulated human NGF-secreting cells in the nonhuman primate: rescue and sprouting of degenerating cholinergic basal forebrain neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Growth-factor gene therapy for neurodegenerative disorders

21 January 2018

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https://api.crossref.org/works/10.1111%2FNEUP.12020

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Neural stem cells improve learning and memory in rats with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cells genetically modified to express human nerve growth factor (NGF) gene restore cognition in the mouse with ibotenic acid-induced cognitive dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Neural stem cells transplantation in cortex in a mouse model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Transplantation of primed or unprimed mouse embryonic stem cell-derived neural precursor cells improves cognitive function in Alzheimerian rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

The cholinergic hypothesis of age and Alzheimer's disease-related cognitive deficits: recent challenges and their implications for novel drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Recent developments in cholinesterases inhibitors for Alzheimer's disease treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cells overexpressing choline acetyltransferase restore cognitive function of kainic acid-induced learning and memory deficit animals.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Cholinergic drugs reverse AF64A-induced impairment of passive avoidance learning in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Human neural stem cells over-expressing choline acetyltransferase restore cognition in rat model of cognitive dysfunction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Recent preclinical evidence advancing cell therapy for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FNEUP.12020

Induction of human neuronal cells by defined transcription factors

21 January 2018

1 reference

COCI

https://opencitations.net/index/coci/api/v1/citations/10.1038/NATURE10202

30 October 2021

Identifiers

DOI

10.1111/NEUP.12020

1 reference

28 August 2017

1 reference