(Q38081171)

28 August 2017

title

IL-22, not simply a Th17 cytokine (English)

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28 August 2017

3

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28 August 2017

Sascha Rutz

1

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Celine Eidenschenk

series ordinal

2

object named as

Céline Eidenschenk

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28 August 2017

publication date

1 March 2013

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28 August 2017

published in

Immunological Reviews

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28 August 2017

volume

252

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28 August 2017

issue

1

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28 August 2017

page(s)

116-132

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Regulation and functions of the IL-10 family of cytokines in inflammation and disease

28 August 2017

cites work

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Human interleukin-10-related T cell-derived inducible factor: molecular cloning and functional characterization as an hepatocyte-stimulating factor

21 January 2018

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Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

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IL-22 in mucosal immunity.

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Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease.

21 January 2018

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Border patrol: regulation of immunity, inflammation and tissue homeostasis at barrier surfaces by IL-22.

21 January 2018

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Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

21 January 2018

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Cutting edge: immune cells as sources and targets of the IL-10 family members?

21 January 2018

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Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides

21 January 2018

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Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.

21 January 2018

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Identification of a human helper T cell population that has abundant production of interleukin 22 and is distinct from T(H)-17, T(H)1 and T(H)2 cells

21 January 2018

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IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines.

21 January 2018

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Interleukin-21 induces the differentiation of human Tc22 cells via phosphorylation of signal transducers and activators of transcription

21 January 2018

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Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals

21 January 2018

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Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria.

21 January 2018

1 reference

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

21 January 2018

1 reference

Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cells

21 January 2018

1 reference

Human NKp44+IL-22+ cells and LTi-like cells constitute a stable RORC+ lineage distinct from conventional natural killer cells

21 January 2018

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Innate lymphoid cells: emerging insights in development, lineage relationships, and function

21 January 2018

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Multiparametric analysis of cytokine-driven human Th17 differentiation reveals a differential regulation of IL-17 and IL-22 production.

21 January 2018

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IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues

21 January 2018

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Expression and regulation of IL-22 in the IL-17-producing CD4+ T lymphocytes

21 January 2018

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Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in T(H)17 cells.

21 January 2018

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Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

21 January 2018

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Human Langerhans cells induce distinct IL-22-producing CD4+ T cells lacking IL-17 production

21 January 2018

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CD1a-autoreactive T cells are a normal component of the human αβ T cell repertoire

21 January 2018

1 reference

Cutting edge: Phenotypic characterization and differentiation of human CD8+ T cells producing IL-17.

21 January 2018

1 reference

Tc17, a unique subset of CD8 T cells that can protect against lethal influenza challenge

21 January 2018

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IL-23 drives pathogenic IL-17-producing CD8+ T cells.

21 January 2018

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A Th17-like developmental process leads to CD8(+) Tc17 cells with reduced cytotoxic activity

21 January 2018

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Cytokine requirements for the differentiation and expansion of IL-17A- and IL-22-producing human Vgamma2Vdelta2 T cells.

21 January 2018

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Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma

21 January 2018

1 reference

Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.

21 January 2018

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Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.

21 January 2018

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IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

21 January 2018

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Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens

21 January 2018

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Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

21 January 2018

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Influence of the transcription factor RORgammat on the development of NKp46+ cell populations in gut and skin

21 January 2018

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RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells

21 January 2018

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AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch

21 January 2018

1 reference

Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22

21 January 2018

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CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut.

21 January 2018

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An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells

21 January 2018

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The lymphotoxin-beta receptor is critical for control of murine Citrobacter rodentium-induced colitis.

21 January 2018

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IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium

21 January 2018

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Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology.

21 January 2018

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Innate lymphoid cells promote anatomical containment of lymphoid-resident commensal bacteria.

21 January 2018

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Identification of the functional interleukin-22 (IL-22) receptor complex: the IL-10R2 chain (IL-10Rbeta ) is a common chain of both the IL-10 and IL-22 (IL-10-related T cell-derived inducible factor, IL-TIF) receptor complexes

21 January 2018

1 reference

Interleukin-10 and related cytokines and receptors

21 January 2018

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Interleukin-22 activates STAT3 and induces IL-10 by colon epithelial cells.

21 January 2018

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Interleukin-22 (IL-22) activates the JAK/STAT, ERK, JNK, and p38 MAP kinase pathways in a rat hepatoma cell line. Pathways that are shared with and distinct from IL-10.

21 January 2018

1 reference

IL-22 increases the innate immunity of tissues

21 January 2018

1 reference

Interleukin-22: a cytokine produced by T, NK and NKT cell subsets, with importance in the innate immune defense and tissue protection

21 January 2018

1 reference

Recent advances in IL-22 biology.

21 January 2018

1 reference

IL-22 mediates mucosal host defense against Gram-negative bacterial pneumonia

21 January 2018

1 reference

IL-22 produced by human NK cells inhibits growth of Mycobacterium tuberculosis by enhancing phagolysosomal fusion

21 January 2018

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Protective immunity to systemic infection with attenuated Salmonella enterica serovar enteritidis in the absence of IL-12 is associated with IL-23-dependent IL-22, but not IL-17.

21 January 2018

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The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

21 January 2018

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Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis

21 January 2018

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Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis

21 January 2018

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IL-22 defines a novel immune pathway of antifungal resistance.

21 January 2018

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Both CD4+ and CD8+ lymphocytes reduce the severity of tissue lesions in murine systemic cadidiasis, and CD4+ cells also demonstrate strain-specific immunopathological effects

21 January 2018

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Patients with chronic mucocutaneous candidiasis exhibit reduced production of Th17-associated cytokines IL-17 and IL-22.

21 January 2018

1 reference

Inborn errors of mucocutaneous immunity to Candida albicans in humans: a role for IL-17 cytokines?

21 January 2018

1 reference

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

21 January 2018

1 reference

Interleukin-22 induces hepatic stellate cell senescence and restricts liver fibrosis in mice

21 January 2018

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Interleukin-22 drives endogenous thymic regeneration in mice

21 January 2018

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Pathological versus protective functions of IL-22 in airway inflammation are regulated by IL-17A

21 January 2018

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Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation

21 January 2018

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Interleukin 22 (IL-22) plays a protective role in T cell-mediated murine hepatitis: IL-22 is a survival factor for hepatocytes via STAT3 activation

21 January 2018

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IL-22-dependent attenuation of T cell-dependent (ConA) hepatitis in herpes virus entry mediator deficiency

21 January 2018

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IL-22 is involved in liver regeneration after hepatectomy

21 January 2018

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Amelioration of high fat diet induced liver lipogenesis and hepatic steatosis by interleukin-22.

21 January 2018

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Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease

21 January 2018

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STAT3 links IL-22 signaling in intestinal epithelial cells to mucosal wound healing

21 January 2018

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Activation of epithelial STAT3 regulates intestinal homeostasis

21 January 2018

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IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.

21 January 2018

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Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

21 January 2018

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Involvement of the IL-22/REG Ialpha axis in ulcerative colitis

21 January 2018

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Interleukin-22 Deficiency Accelerates the Rejection of Full Major Histocompatibility Complex-Disparate Heart Allografts

21 January 2018

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Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats

21 January 2018

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IL-22-induced regulatory CD11b+ APCs suppress experimental autoimmune uveitis

21 January 2018

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γδ T cells protect against lung fibrosis via IL-22.

21 January 2018

1 reference

A novel role for IL-22R1 as a driver of inflammation

21 January 2018

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The biological functions of T helper 17 cell effector cytokines in inflammation

21 January 2018

1 reference

Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but independent of IL-17.

21 January 2018

1 reference

IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not.

21 January 2018

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Proinflammatory role of the Th17 cytokine interleukin-22 in collagen-induced arthritis in C57BL/6 mice

21 January 2018

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Expression of interleukin-22 in rheumatoid arthritis: potential role as a proinflammatory cytokine.

21 January 2018

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Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes

21 January 2018

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Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

21 January 2018

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Interferon-α-conditioned human monocytes combine a Th1-orienting attitude with the induction of autologous Th17 responses: role of IL-23 and IL-12.

21 January 2018

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21 January 2018

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IL-22+ CD4+ T cells are associated with therapeutic trichuris trichiura infection in an ulcerative colitis patient.

21 January 2018

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Interleukin-23 promotes Th17 differentiation by inhibiting T-bet and FoxP3 and is required for elevation of interleukin-22, but not interleukin-21, in autoimmune experimental arthritis.

21 January 2018

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TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

21 January 2018

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Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

21 January 2018

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TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

21 January 2018

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Essential autocrine regulation by IL-21 in the generation of inflammatory T cells

21 January 2018

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IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells

21 January 2018

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

21 January 2018

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IL-21 and IL-21R are not required for development of Th17 cells and autoimmunity in vivo

21 January 2018

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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells

21 January 2018

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Expansion of human NK-22 cells with IL-7, IL-2, and IL-1beta reveals intrinsic functional plasticity

21 January 2018

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Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state TH17 cells in the intestine

21 January 2018

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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

21 January 2018

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T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma

21 January 2018

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TGF-beta-induced Foxp3 inhibits T(H)17 cell differentiation by antagonizing RORgammat function

21 January 2018

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Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

21 January 2018

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The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat

21 January 2018

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The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells

21 January 2018

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Transforming growth factor-beta induces development of the T(H)17 lineage

21 January 2018

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IL-21 and TGF-beta are required for differentiation of human T(H)17 cells

21 January 2018

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c-Maf negatively regulates ARE-mediated detoxifying enzyme genes expression and anti-oxidant induction

21 January 2018

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c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation

21 January 2018

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Cutting edge: IL-27 induces the transcription factor c-Maf, cytokine IL-21, and the costimulatory receptor ICOS that coordinately act together to promote differentiation of IL-10-producing Tr1 cells

21 January 2018

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Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose

21 January 2018

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c-Maf regulates IL-10 expression during Th17 polarization

21 January 2018

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Transcriptional regulation of th2 differentiation by inducible costimulator

21 January 2018

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The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.

21 January 2018

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The costimulatory molecule ICOS regulates the expression of c-Maf and IL-21 in the development of follicular T helper cells and TH-17 cells

21 January 2018

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The inducible costimulator (ICOS) is critical for the development of human T(H)17 cells.

21 January 2018

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Interleukin-27-mediated suppression of human Th17 cells is associated with activation of STAT1 and suppressor of cytokine signaling protein 1.

21 January 2018

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Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

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Regulation of interleukin-10 and interleukin-22 expression in T helper cells

21 January 2018

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The aryl hydrocarbon receptor in immunity

21 January 2018

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Modulation of Th17 development and function by activation of the aryl hydrocarbon receptor--the role of endogenous ligands.

21 January 2018

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Aryl hydrocarbon receptor regulates Stat1 activation and participates in the development of Th17 cells.

21 January 2018

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The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

21 January 2018

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Control of T(reg) and T(H)17 cell differentiation by the aryl hydrocarbon receptor

21 January 2018

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Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset.

21 January 2018

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Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.

21 January 2018

1 reference

Batf coordinates multiple aspects of B and T cell function required for normal antibody responses

21 January 2018

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Stat3-dependent induction of BATF in M1 mouse myeloid leukemia cells

21 January 2018

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IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype

21 January 2018

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Prostaglandin E2 suppresses antifungal immunity by inhibiting interferon regulatory factor 4 function and interleukin-17 expression in T cells.

21 January 2018

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Critical regulation of early Th17 cell differentiation by interleukin-1 signaling

21 January 2018

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IRF-4-binding protein inhibits interleukin-17 and interleukin-21 production by controlling the activity of IRF-4 transcription factor.

21 January 2018

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IRF4 regulates IL-17A promoter activity and controls RORγt-dependent Th17 colitis in vivo.

21 January 2018

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The role of IRF-4 in transcriptional regulation

21 January 2018

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Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition.

21 January 2018

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Notch signaling drives IL-22 secretion in CD4+ T cells by stimulating the aryl hydrocarbon receptor.

21 January 2018

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Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signalling

21 January 2018

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Notch regulates IL-10 production by T helper 1 cells

21 January 2018

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Lymphotoxin-β receptor-independent development of intestinal IL-22-producing NKp46+ innate lymphoid cells

21 January 2018

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Increased expression of interleukin-22 by synovial Th17 cells during late stages of murine experimental arthritis is controlled by interleukin-1 and enhances bone degradation

21 January 2018

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Th22 cells represent a distinct human T cell subset involved in epidermal immunity and remodeling

21 January 2018

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI40202

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

1 reference

31 May 2024

https://opencitations.net/index/api/v1/citations/10.1172/JCI33194

Identifiers

DOI

10.1111/IMR.12027

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28 August 2017

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