(Q36491342)

14 August 2017

Notch regulates IL-10 production by T helper 1 cells (English)

1 reference

14 August 2017

6

Alexander Scheffold

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author name string

Sascha Rutz

1

1 reference

14 August 2017

Marko Janke

2

1 reference

14 August 2017

Nadine Kassner

3

1 reference

14 August 2017

Thordis Hohnstein

4

1 reference

14 August 2017

Manuela Krueger

5

1 reference

14 August 2017

language of work or name

English

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publication date

21 February 2008

1 reference

Proceedings of the National Academy of Sciences of the United States of America

14 August 2017

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14 August 2017

105

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14 August 2017

3497-3502

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14 August 2017

9

1 reference

Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Notch directly regulates Gata3 expression during T helper 2 cell differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

CD8- DCs induce IL-12-independent Th1 differentiation through Delta 4 Notch-like ligand in response to bacterial LPS

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Notch signalling during peripheral T-cell activation and differentiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Tyk2 negatively regulates adaptive Th1 immunity by mediating IL-10 signaling and promoting IFN-gamma-dependent IL-10 reactivation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Notch signaling is an important regulator of type 2 immunity.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Selected Toll-like receptor agonist combinations synergistically trigger a T helper type 1-polarizing program in dendritic cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Conditional deletion of Gata3 shows its essential function in T(H)1-T(H)2 responses.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Interleukin-2 is essential for CD4+CD25+ regulatory T cell function

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Notch 1 signaling regulates peripheral T cell activation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Interleukin-10 and the interleukin-10 receptor

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Functional diversity of helper T lymphocytes

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Flow cytometric determination of cytokines in activated murine T helper lymphocytes: expression of interleukin-10 in interferon-gamma and in interleukin-4-expressing cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2265185

Expression of IL-10 in Th memory lymphocytes is conditional on IL-12 or IL-4, unless the IL-10 gene is imprinted by GATA-3.

28 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Notch signaling augments T cell responsiveness by enhancing CD25 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Notch ligands Delta-like1, Delta-like4 and Jagged1 differentially regulate activation of peripheral T helper cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Delta1-Notch3 interactions bias the functional differentiation of activated CD4+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

The nervous system and innate immunity: the neuropeptide connection

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Regulation of alphabeta/gammadelta T cell lineage commitment and peripheral T cell responses by Notch/RBP-J signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0712102105

Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells

21 January 2018

1 reference

12 December 2020

IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses

1 reference

12 December 2020

CD4+ T Cell Clones Producing both Interferon-γ and Interleukin-10 Predominate in Bronchoalveolar Lavages of Active Pulmonary Tuberculosis Patients

1 reference

12 December 2020

Inhibitors of gamma-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21

1 reference

12 December 2020

Suppression of autoimmune inflammation of the central nervous system by interleukin 10 secreted by interleukin 27-stimulated T cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0712102105

1 reference

14 August 2017

0 references

1 reference

14 August 2017

1 reference