(Q55045567)

16 June 2018

title

A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. (English)

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16 June 2018

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9

Howard L Weiner

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16 June 2018

Jean Pierre Peron

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object named as

Jean P S Peron

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16 June 2018

6

Richard A Flavell

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16 June 2018

author name string

Amit Awasthi

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16 June 2018

Yijun Carrier

2

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16 June 2018

Estelle Bettelli

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16 June 2018

Masahito Kamanaka

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16 June 2018

Vijay K Kuchroo

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16 June 2018

Mohamed Oukka

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16 June 2018

language of work or name

English

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publication date

11 November 2007

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16 June 2018

published in

Nature Immunology

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16 June 2018

volume

8

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16 June 2018

page(s)

1380-1389

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16 June 2018

issue

12

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16 June 2018

Development in motion: helper T cells at work

cites work

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7 January 2021

Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

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Interleukin-10-deficient mice develop chronic enterocolitis

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Characterization of Dendritic Cells that Induce Tolerance and T Regulatory 1 Cell Differentiation In Vivo

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A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

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7 January 2021

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

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7 January 2021

Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

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7 January 2021

Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells

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7 January 2021

Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice

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7 January 2021

Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.

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7 January 2021

Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice

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7 January 2021

The diabetes susceptibility locus Idd5.1 on mouse chromosome 1 regulates ICOS expression and modulates murine experimental autoimmune encephalomyelitis.

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7 January 2021

Cutting Edge: Role of IL-27/WSX-1 Signaling for Induction of T-Bet Through Activation of STAT1 During Initial Th1 Commitment

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7 January 2021

Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system

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7 January 2021

Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells

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7 January 2021

WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27

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7 January 2021

The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection.

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7 January 2021

IL-10 released by concomitant TLR2 stimulation blocks the induction of a subset of Th1 cytokines that are specifically induced by TLR4 or TLR3 in human dendritic cells

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7 January 2021

T(H)1 cells control themselves by producing interleukin-10.

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7 January 2021

An altered peptide ligand mediates immune deviation and prevents autoimmune encephalomyelitis

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7 January 2021

Natural interferon alpha/beta-producing cells link innate and adaptive immunity

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7 January 2021

Generation of human CD8 T regulatory cells by CD40 ligand-activated plasmacytoid dendritic cells

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7 January 2021

Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.

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7 January 2021

Small intestine lamina propria dendritic cells promote de novo generation of Foxp3 T reg cells via retinoic acid

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7 January 2021

Discovery and biology of IL-23 and IL-27: related but functionally distinct regulators of inflammation

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7 January 2021

IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3

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7 January 2021

A novel transcription factor, T-bet, directs Th1 lineage commitment

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7 January 2021

The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells

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7 January 2021

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells

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7 January 2021

Increased susceptibility of mice lacking T-bet to infection with Mycobacterium tuberculosis correlates with increased IL-10 and decreased IFN-gamma production

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7 January 2021

Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses.

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7 January 2021

GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4+ T cells.

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7 January 2021

Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression.

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7 January 2021

IL-27 regulates IL-12 responsiveness of naive CD4+ T cells through Stat1-dependent and -independent mechanisms

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7 January 2021

Regulation of T helper cell differentiation by STAT molecules.

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7 January 2021

IL-27 controls the development of inducible regulatory T cells and Th17 cells via differential effects on STAT1

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7 January 2021

IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3.

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7 January 2021

Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor

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7 January 2021

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

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7 January 2021

IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3.

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7 January 2021

Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouse

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7 January 2021

Identifiers

DOI

10.1038/NI1541

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16 June 2018

PubMed ID

17994022

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16 June 2018