(Q38085460)

28 August 2017

The neurobiology of bipolar disorder: identifying targets for specific agents and synergies for combination treatment (English)

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28 August 2017

1 reference

1

Ana C Andreazza

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28 August 2017

L Trevor Young

2

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PubMed ID

23449044

28 August 2017

language of work or name

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1 March 2013

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The International Journal of Neuropsychopharmacology

28 August 2017

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28 August 2017

17

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28 August 2017

1039-1052

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28 August 2017

7

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Lithium in neuropsychiatry: a 2010 update

28 August 2017

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

GSK-3 is a viable potential target for therapeutic intervention in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Lipid peroxidation and antioxidant enzyme levels in patients with schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Attenuation of ketamine effects by nimodipine pretreatment in recovering ethanol dependent men: psychopharmacologic implications of the interaction of NMDA and L-type calcium channel antagonists

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Mitochondria, oligodendrocytes and inflammation in bipolar disorder: evidence from transcriptome studies points to intriguing parallels with multiple sclerosis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Molecular evidence for mitochondrial dysfunction in bipolar disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Inhibition of glycogen synthase kinase-3 protects cells from intrinsic but not extrinsic oxidative stress

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Altered expression of apoptotic factors and synaptic markers in postmortem brain from bipolar disorder patients

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Effects of the CACNA1C risk allele for bipolar disorder on cerebral gray matter volume in healthy individuals

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Molecular neurobiology of bipolar disorder: a disease of 'mood-stabilizing neurons'?

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

A systemic toxicity index developed to assess peripheral changes in mood episodes

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Evidence for the impact of the CACNA1C risk allele rs1006737 on 2-year cognitive functioning in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Amphetamine metabolism in amphetamine psychosis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Oxidative stress markers in bipolar disorder: a meta-analysis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Serum S100B and antioxidant enzymes in bipolar patients.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

An epidemiologic and clinical overview of medical and psychopathological comorbidities in major psychoses.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Hypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

On the catecholamine innervation of the hypothalamus, with special reference to the median eminence.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Altered expression of mitochondria-related genes in postmortem brains of patients with bipolar disorder or schizophrenia, as revealed by large-scale DNA microarray analysis.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Generation of the Neurotoxin 6-Hydroxydopamine by Peroxidase/H2O2 Oxidation of Dopamine

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Possible involvement of endorphin withdrawal or imbalance in specific premenstrual syndromes and postpartum depression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Epigenetic GABAergic targets in schizophrenia and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Is response to prophylactic lithium a familial trait?

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Emerging experimental therapeutics for bipolar disorder: insights from the molecular and cellular actions of current mood stabilizers

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Targeting glycogen synthase kinase-3 as an approach to develop novel mood-stabilising medications

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Cardiovascular disease and hypertension among adults with bipolar I disorder in the United States

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Expression profiling in neuropsychiatric disorders: emphasis on glutamate receptors in bipolar disorder

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Changes in nitric oxide level and superoxide dismutase activity during antimanic treatment.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Catechol-O-methyltransferase gene regulation in rat frontal cortex.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Alternative splicing of human insulin-degrading enzyme yields a novel isoform with a decreased ability to degrade insulin and amyloid beta-protein

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genetic variation in CACNA1C affects brain circuitries related to mental illness

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The Bcl-2 gene polymorphism rs956572AA increases inositol 1,4,5-trisphosphate receptor-mediated endoplasmic reticulum calcium release in subjects with bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Novel glutamatergic agents for major depressive disorder and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Oxidative stress parameters in unmedicated and treated bipolar subjects during initial manic episode: A possible role for lithium antioxidant effects

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Decreased NR1, NR2A, and SAP102 transcript expression in the hippocampus in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Regional prefrontal gray and white matter abnormalities in bipolar disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Free radical oxidation of cardiolipin: chemical mechanisms, detection and implication in apoptosis, mitochondrial dysfunction and human diseases

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Gene-expression studies in understanding the mechanism of action of lithium

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Serum brain-derived neurotrophic factor in euthymic bipolar patients on prophylactic lithium therapy.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Behavioral, biochemical and neuroendocrine responses to amphetamine in normal twins and 'well-state' bipolar patients.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

DNA hypomethylation of MB-COMT promoter in the DNA derived from saliva in schizophrenia and bipolar disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Oxidative damage to mitochondrial complex I due to peroxynitrite: identification of reactive tyrosines by mass spectrometry

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Transcription factor SP4 is a susceptibility gene for bipolar disorder

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Singleton deletions throughout the genome increase risk of bipolar disorder

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Bipolar disorder: candidate drug targets

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Increased oxidative stress in the anterior cingulate cortex of subjects with bipolar disorder and schizophrenia.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Defects of mitochondrial electron transport chain in bipolar disorder: implications for mood-stabilizing treatment

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Mitochondrial related gene expression changes are sensitive to agonal-pH state

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Free radicals and antioxidants in normal physiological functions and human disease

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Bcl-2 SNP rs956572 associates with disrupted intracellular calcium homeostasis in bipolar I disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genome-wide linkage scan in a large bipolar disorder sample from the National Institute of Mental Health genetics initiative suggests putative loci for bipolar disorder, psychosis, suicide, and panic disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Prevalence and correlates of bipolar spectrum disorder in the world mental health survey initiative

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Strategies to identify genes for complex disorders: a focus on bipolar disorder and chromosome 16p.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

COMT genotype increases risk for bipolar I disorder and influences neurocognitive performance

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Selective neuron loss in the paraventricular nucleus of hypothalamus in patients suffering from major depression and bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Modeling psychiatric disorders at the cellular and network levels

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https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Lithium response and genetic variation in the CREB family of genes

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Low glial numbers in the amygdala in major depressive disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The course of nitric oxide and superoxide dismutase during treatment of bipolar depressive episode

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The neurobiology of bipolar disorder: focus on signal transduction pathways and the regulation of gene expression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Pathways underlying neuroprogression in bipolar disorder: focus on inflammation, oxidative stress and neurotrophic factors

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Dopamine dysregulation syndrome: implications for a dopamine hypothesis of bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The density of pyramidal and nonpyramidal neurons in anterior cingulate cortex of schizophrenic and bipolar subjects

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Lithium inhibits Smad3/4 transactivation via increased CREB activity induced by enhanced PKA and AKT signaling

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The expression of proapoptosis genes is increased in bipolar disorder, but not in schizophrenia

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The impact of the Val158Met catechol-O-methyltransferase genotype on neural correlates of sad facial affect processing in patients with bipolar disorder and their relatives

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

A reduction of nonpyramidal cells in sector CA2 of schizophrenics and manic depressives.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

COMT and BDNF interacted in bipolar II disorder not comorbid with anxiety disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Verapamil augmentation of lithium treatment improves outcome in mania unresponsive to lithium alone: preliminary findings and a discussion of therapeutic mechanisms

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Associated disturbances in calcium homeostasis and G protein-mediated cAMP signaling in bipolar I disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Calcium homeostasis in long-term lithium-treated women with bipolar affective disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Markers of glutamate synaptic transmission and plasticity are increased in the anterior cingulate cortex in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Intracellular calcium signalling in peripheral cells of patients with bipolar affective disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Decreased antioxidant enzymes and membrane essential polyunsaturated fatty acids in schizophrenic and bipolar mood disorder patients

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genes, cognition and brain through a COMT lens

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Reductions in neuronal and glial density characterize the dorsolateral prefrontal cortex in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Depression: what we can learn from postmortem studies

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Lithium increases plasma brain-derived neurotrophic factor in acute bipolar mania: a preliminary 4-week study

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Specific phosphorylation of a site in the full-length form of the alpha 1 subunit of the cardiac L-type calcium channel by adenosine 3',5'-cyclic monophosphate-dependent protein kinase

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

A genomewide association study of response to lithium for prevention of recurrence in bipolar disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Glial reduction in the subgenual prefrontal cortex in mood disorders

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

The COMT and DRD3 genes interacted in bipolar I but not bipolar II disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

A genome-wide association study implicates diacylglycerol kinase eta (DGKH) and several other genes in the etiology of bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Can bipolar disorder be viewed as a multi-system inflammatory disease?

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Neurobiological trait abnormalities in bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Cytoprotection by lithium and valproate varies between cell types and cellular stresses

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Advances in bipolar disorder: selected sessions from the 2011 International Conference on Bipolar Disorder.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

CACNA1C gene polymorphisms, cardiovascular disease outcomes, and treatment response

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genome-wide association study of bipolar disorder in European American and African American individuals

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Whole-genome association study of bipolar disorder

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Examining the dopamine hypotheses of schizophrenia and of mania using the prolactin response to antipsychotic drugs

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

COMT: a common susceptibility gene in bipolar disorder and schizophrenia.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Genetic research into bipolar disorder: the need for a research framework that integrates sophisticated molecular biology and clinically informed phenotype characterization

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Elevated serum nitric oxide and superoxide dismutase in euthymic bipolar patients: impact of past episodes.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Prophylactic lithium response and polymorphism of the brain-derived neurotrophic factor gene.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Functional polymorphism of matrix metalloproteinase-9 (MMP-9) gene and response to lithium prophylaxis in bipolar patients

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

Clinical and pathogenic aspects of candidate genes for lithium prophylactic efficacy.

1 reference

https://api.crossref.org/works/10.1017%2FS1461145713000096

7 January 2021

10.1017/S1461145713000096

Identifiers

DOI

1 reference

28 August 2017

1 reference

PubMed ID

23449044