(Q38088804)

28 August 2017

Measuring the tyrosine kinase activity: a review of biochemical and cellular assay technologies (English)

1 reference

28 August 2017

Yong Jia

1

1 reference

28 August 2017

Xiang-Ju Gu

series ordinal

2

1 reference

28 August 2017

Achim Brinker

series ordinal

3

1 reference

28 August 2017

Markus Warmuth

series ordinal

4

1 reference

28 August 2017

language of work or name

English

0 references

publication date

1 August 2008

1 reference

Expert Opinion on Drug Discovery

28 August 2017

1 reference

28 August 2017

3

1 reference

28 August 2017

8

1 reference

28 August 2017

959-978

1 reference

The protein kinase complement of the human genome

28 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Signaling--2000 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Inhibitors of angiogenesis and cancer-related receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Kinases as therapeutic targets for heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Targeting JNK3 for the treatment of neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

The development and therapeutic potential of protein kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Protein kinases--the major drug targets of the twenty-first century?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Protein kinase inhibitors as a therapeutic modality

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Oncogenic kinase signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Cell signaling by receptor tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Receptor tyrosine kinases and anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Tyrosine kinases as targets in cancer therapy - successes and failures

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Receptor tyrosine kinases: the main targets for new anticancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

From oncogene to drug: development of small molecule tyrosine kinase inhibitors as anti-tumor and anti-angiogenic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Tyrosine kinase inhibitors: rationale, mechanisms of action, and implications for drug resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

EGFR tyrosine kinase inhibitor "gefitinib (Iressa)" for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Assays for membrane tyrosine kinase receptors: methods for high-throughput screening and utility for diagnostics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput screening: advances in assay technologies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Fluorescence assays for high-throughput screening of protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput screening for kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Application of fluorescence polarization to enzyme assays and single nucleotide polymorphism genotyping: some recent developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Tyrosine protein kinase assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Detection of protein tyrosine kinase activity using a high-capacity streptavidin-coated membrane and optimized biotinylated peptide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput screening assay for identification of small molecule inhibitors of Aurora2/STK15 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Identification of inhibitors of the kinase activity of oncogenic V600E BRAF in an enzyme cascade high-throughput screen

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A Widely Applicable, High-Throughput TR-FRET Assay for the Measurement of Kinase Autophosphorylation: VEGFR-2 as a Prototype

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Assay concordance between SPA and TR-FRET in high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Fluorescence polarization competition immunoassay for tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Readout technologies for highly miniaturized kinase assays applicable to high-throughput screening in a 1536-well format.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Data Concordance from a Comparison between Filter Binding and Fluorescence Polarization Assay Formats for Identification of ROCK-II Inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

An evaluation of fluorescence polarization and lifetime discriminated polarization for high throughput screening of serine/threonine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Detection of phosphopeptides by fluorescence polarization in the presence of cationic polyamino acids: application to kinase assays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Development and application of fluorescence polarization assays in drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Fluorescence polarization and anisotropy in high throughput screening: perspectives and primer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

AlphaScreen kinase HTS platforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Miniaturization and validation of a high-throughput serine kinase assay using the AlphaScreen platform

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Further comparison of primary hit identification by different assay technologies and effects of assay measurement variability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Development of a fluorescence polarization AKT serine/threonine kinase assay using an immobilized metal ion affinity-based technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput screening with immobilized metal ion affinity-based fluorescence polarization detection, a homogeneous assay for protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A homogeneous fluorescence polarization assay adaptable for a range of protein serine/threonine and tyrosine kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Using IMAP technology to identify kinase inhibitors: comparison with a substrate depletion approach and analysis of the nature of false positives

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Determining appropriate substrate conversion for enzymatic assays in high-throughput screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A microchip-based enzyme assay for protein kinase A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Assay development and screening of a serine/threonine kinase in an on-chip mode using caliper nanofluidics technology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Development and validation of a fluorescence technology for both primary and secondary screening of kinases that facilitates compound selectivity and site-specific inhibitor determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Applications of fluorescent polymer superquenching to high throughput screening assays for protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Metal ion-mediated polymer superquenching for highly sensitive detection of kinase and phosphatase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A simple strategy for mitigating the effect of data variability on the identification of active chemotypes from high-throughput screening data

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A homogeneous, nonradioactive high-throughput fluorogenic protein kinase assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Identification of kinase inhibitors by an ATP depletion method

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Firefly bioluminescence assay of ATP using diethylaminoethyl–dextran as an enhancer in the presence of sodium chloride and ATP extranctant

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput screening with quantitation of ATP consumption: a universal non-radioisotope, homogeneous assay for protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A generic, homogenous method for measuring kinase and inhibitor activity via adenosine 5'-diphosphate accumulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Application of meso scale technology for the measurement of phosphoproteins in human tumor xenografts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Determination of ligand binding affinities for endogenous seven-transmembrane receptors using fluorometric microvolume assay technology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

High-throughput cellular assays for regulated posttranslational modifications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Cellular Ser/Thr-kinase assays using generic peptide substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

An efficient rapid system for profiling the cellular activities of molecular libraries.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Cell-based high-content screening of small-molecule libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Image-based chemical screening

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A miniaturized cell-based fluorescence resonance energy transfer assay for insulin-receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Genetically encoded reporters of protein kinase A activity reveal impact of substrate tethering

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Genetically encoded fluorescent reporters of protein tyrosine kinase activities in living cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

A genetically encoded fluorescent reporter reveals oscillatory phosphorylation by protein kinase C

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Molecular imaging of Akt kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Transformation of an interleukin 3-dependent hematopoietic cell line by the chronic myelogenous leukemia-specific P210bcr/abl protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Miniaturized, ultra-high throughput screening of tyrosine kinases using homogeneous, competitive fluorescence immunoassays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

Two simple and generic antibody-independent kinase assays: comparison of a bioluminescent and a microfluidic assay format

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F17460441.3.8.959

21 January 2018

Identifiers

DOI

10.1517/17460441.3.8.959

1 reference

release_7glauda2orgulgju54s5jygdm4

28 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/7glauda2orgulgju54s5jygdm4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference