(Q38088874)

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Intracellular protein degradation: from a vague idea through the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting

scientific article published on 08 February 2013

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scholarly article

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Europe PubMed Central

28 August 2017

Intracellular protein degradation: from a vague idea through the lysosome and the ubiquitin-proteasome system and onto human diseases and drug targeting (English)

1 reference

Europe PubMed Central

28 August 2017

ubiquitin-proteasome system

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Aaron Ciechanover

1

object named as

Aaron Ciechanover

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Europe PubMed Central

28 August 2017

language of work or name

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publication date

8 February 2013

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Europe PubMed Central

28 August 2017

Bioorganic & Medicinal Chemistry

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Europe PubMed Central

28 August 2017

21

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Europe PubMed Central

28 August 2017

3400-3410

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Europe PubMed Central

28 August 2017

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1 reference

Europe PubMed Central

28 August 2017

Occurrence of a polyubiquitin structure in ubiquitin-protein conjugates

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction

1 reference

11 October 2022

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Mechanisms of chaperone-mediated autophagy

1 reference

11 October 2022

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Transcriptional regulation by histone ubiquitination and deubiquitination.

1 reference

11 October 2022

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Hitler's gift and the era of biosynthesis

1 reference

11 October 2022

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Selective control of the degradation of normal and aberrant proteins in Reuber H35 hepatoma cells

1 reference

11 October 2022

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Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Proposed role of ATP in protein breakdown: conjugation of protein with multiple chains of the polypeptide of ATP-dependent proteolysis

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Studies on the induced synthesis of β-galactosidase in Escherichia coli: The kinetics and mechanism of sulfur incorporation

1 reference

11 October 2022

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A multiubiquitin chain is confined to specific lysine in a targeted short-lived protein

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

ATP-dependent conjugation of reticulocyte proteins with the polypeptide required for protein degradation

1 reference

11 October 2022

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Red light-induced formation of ubiquitin-phytochrome conjugates: Identification of possible intermediates of phytochrome degradation.

1 reference

11 October 2022

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ATP-dependent degradation of ubiquitin-protein conjugates

1 reference

11 October 2022

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The complete amino acid sequence of ubiquitin, an adenylate cyclase stimulating polypeptide probably universal in living cells

1 reference

11 October 2022

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Ubiquitin dependence of selective protein degradation demonstrated in the mammalian cell cycle mutant ts85

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Observations on intracellular protein catabolism studied in vitro

1 reference

11 October 2022

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The effect of protease inhibitors and decreased temperature on the degradation of different classes of proteins in cultured hepatocytes

1 reference

11 October 2022

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Remarkable similarities of peptide fingerprints of histone 2A and nonhistone chromosomal protein A24

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Proteolysis: from the lysosome to ubiquitin and the proteasome

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Functions of lysosomes

1 reference

11 October 2022

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A soluble ATP-dependent proteolytic system responsible for the degradation of abnormal proteins in reticulocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Control of enzyme levels in animal tissues

1 reference

11 October 2022

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How the ubiquitin-proteasome system controls transcription

1 reference

11 October 2022

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Diseases of function and stability of haemoglobin

1 reference

11 October 2022

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Attempts to Map a Process Evolution of Peptide Biosynthesis

1 reference

11 October 2022

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Isopeptide linkage between nonhistone and histone 2A polypeptides of chromosomal conjugate-protein A24

1 reference

11 October 2022

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Cation-sensitive neutral endopeptidase: isolation and specificity of the bovine pituitary enzyme

1 reference

11 October 2022

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Effect of ATP on Protein Degradation in Rat Liver Lysosomes

1 reference

11 October 2022

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Enzymic Content of the Mitochondria Fraction

1 reference

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In vivo degradation of a transcriptional regulator: the yeast alpha 2 repressor

1 reference

11 October 2022

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A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

ATP-dependent incorporation of 20S protease into the 26S complex that degrades proteins conjugated to ubiquitin

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Turnover of protein in growing and non-growing populations of Escherichia coli

1 reference

11 October 2022

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Decrease in uH2A (protein A24) of a mouse temperature‐sensitive mutant

1 reference

11 October 2022

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The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

1 reference

11 October 2022

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Conjugation of ubiquitin to denatured hemoglobin is proportional to the rate of hemoglobin degradation in HeLa cells

1 reference

11 October 2022

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Amino-terminal sequence identity of ubiquitin and the nonhistone component of nuclear protein A24

1 reference

11 October 2022

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Degradation of nuclear oncoproteins by the ubiquitin system in vitro

1 reference

11 October 2022

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Proteasomes and their kin: proteases in the machine age

1 reference

11 October 2022

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Molecular mechanisms of bitter and sweet taste transduction

1 reference

11 October 2022

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Some characteristics of the alanine aminotransferase- and arginase-inactivating system of lysosomes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Cyclin is degraded by the ubiquitin pathway

1 reference

11 October 2022

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Isolation of a polypeptide that has lymphocyte-differentiating properties and is probably represented universally in living cells

1 reference

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Potential for proteasome inhibition in the treatment of cancer

1 reference

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Tissue fractionation studies. 4. Comparative study of the binding of acid phosphatase, β-glucuronidase and cathepsin by rat-liver particles

1 reference

11 October 2022

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N-terminal ubiquitination: more protein substrates join in.

1 reference

11 October 2022

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Isolation of bovine thymin: a polypeptide hormone of the thymus

1 reference

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Cytoplasmic components in hepatic cell lysosomes

1 reference

11 October 2022

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Intracellular protein catabolism and its control during nutrient deprivation and supply

1 reference

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Intracellular protein degradation in mammalian and bacterial cells: Part 2

1 reference

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Impressions of an organic chemist in biochemistry.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Lysosomes, a meeting point of proteins, chaperones, and proteases

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

A protein conjugation system essential for autophagy

1 reference

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H2B ubiquitylation: the end is in sight

1 reference

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https://opencitations.net/index/coci/api/v1/references/10.1016/J.BMC.2013.01.056

Identifiers

10.1016/J.BMC.2013.01.056

1 reference

Europe PubMed Central

28 August 2017

1 reference

Europe PubMed Central

28 August 2017

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