(Q38095764)

28 August 2017

The complex genetic landscape of familial breast cancer (English)

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28 August 2017

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Lorenzo Melchor

1

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PubMed ID

23552954

28 August 2017

Javier Benítez

series ordinal

2

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28 August 2017

5 April 2013

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28 August 2017

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28 August 2017

132

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28 August 2017

8

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28 August 2017

845-863

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https://scigraph.springernature.com/pub.10.1007/s00439-013-1299-y

28 August 2017

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cites work

Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers

1 reference

12 December 2020

PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene

1 reference

12 December 2020

Evolutionary pathways in BRCA1-associated breast tumors

1 reference

12 December 2020

Transcriptional characteristics of familial non-BRCA1/BRCA2 breast tumors.

1 reference

12 December 2020

Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene

1 reference

12 December 2020

Histopathological features of 'BRCAX' familial breast cancers in the kConFab resource

1 reference

12 December 2020

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

1 reference

12 December 2020

Somatic deletions in hereditary breast cancers implicate 13q21 as a putative novel breast cancer susceptibility locus

1 reference

12 December 2020

Quantitative copy number analysis by Multiplex Ligation-dependent Probe Amplification (MLPA) of BRCA1-associated breast cancer regions identifies BRCAness

1 reference

12 December 2020

A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers

1 reference

12 December 2020

The current structural and functional understanding of APOBEC deaminases

1 reference

12 December 2020

Gene expression profiling of formalin-fixed, paraffin-embedded familial breast tumours using the whole genome-DASL assay

1 reference

12 December 2020

Distinct genomic aberration patterns are found in familial breast cancer associated with different immunohistochemical subtypes

1 reference

12 December 2020

The molecular pathology of hereditary breast cancer

1 reference

12 December 2020

Ploidy and large-scale genomic instability consistently identify basal-like breast carcinomas with BRCA1/2 inactivation

1 reference

12 December 2020

Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH

1 reference

12 December 2020

Molecular classification of breast carcinomas by comparative genomic hybridization: a specific somatic genetic profile for BRCA1 tumors

1 reference

12 December 2020

Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancer

1 reference

12 December 2020

Genome-wide association study identifies novel breast cancer susceptibility loci

1 reference

12 December 2020

Inherited mutations in breast cancer genes--risk and response

1 reference

12 December 2020

Morphology of breast cancer as a means of triage of patients for BRCA1 genetic testing.

1 reference

12 December 2020

Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

1 reference

12 December 2020

Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles

1 reference

12 December 2020

Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

1 reference

12 December 2020

Array comparative genomic hybridization and its applications in cancer

1 reference

12 December 2020

The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer

1 reference

12 December 2020

Immunohistochemical Expression of DNA Repair Proteins in Familial Breast Cancer DifferentiateBRCA2-Associated Tumors

1 reference

12 December 2020

Distinct genomic profiles in hereditary breast tumors identified by array-based comparative genomic hybridization

1 reference

12 December 2020

Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis

1 reference

12 December 2020

Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics

1 reference

12 December 2020

Molecular portraits of human breast tumours

1 reference

12 December 2020

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

1 reference

12 December 2020

Genomic and transcriptional aberrations linked to breast cancer pathophysiologies

1 reference

12 December 2020

Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns

1 reference

12 December 2020

Gene expression profiling predicts clinical outcome of breast cancer

1 reference

12 December 2020

Distinction between hereditary and sporadic breast cancer on the basis of clinicopathological data

1 reference

12 December 2020

The molecular portraits of breast tumors are conserved across microarray platforms

1 reference

12 December 2020

A microRNA expression signature of human solid tumors defines cancer gene targets

1 reference

12 December 2020

Genetic anticipation is associated with telomere shortening in hereditary breast cancer.

1 reference

12 December 2020

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations

1 reference

12 December 2020

Functions and regulation of the APOBEC family of proteins

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12 December 2020

The life history of 21 breast cancers

1 reference

12 December 2020

Repeated observation of breast tumor subtypes in independent gene expression data sets

1 reference

12 December 2020

Immunohistochemical classification of non-BRCA1/2 tumors identifies different groups that demonstrate the heterogeneity of BRCAX families

1 reference

12 December 2020

A non-BRCA1/2 hereditary breast cancer sub-group defined by aCGH profiling of genetically related patients.

1 reference

12 December 2020

Amplification of the BRCA2 Pathway Gene EMSY in Sporadic Breast Cancer Is Related to Negative Outcome

1 reference

12 December 2020

Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutations

1 reference

12 December 2020

Exome sequencing reveals a novel Fanconi group defined by XRCC2 mutation

1 reference

12 December 2020

Estrogen Receptor Status Could Modulate the Genomic Pattern in Familial and Sporadic Breast Cancer

1 reference

12 December 2020

Low rate of TP53 germline mutations in breast cancer/sarcoma families not fulfilling classical criteria for Li-Fraumeni syndrome

1 reference

12 December 2020

A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1

1 reference

12 December 2020

Integration of BRCA1-mediated miRNA and mRNA profiles reveals microRNA regulation of TRAF2 and NFκB pathway.

1 reference

12 December 2020

A study of the PTEN/MMAC1 gene in 136 breast cancer families

1 reference

12 December 2020

Screening for germ line TP53 mutations in breast cancer patients

1 reference

12 December 2020

Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155

1 reference

12 December 2020

Breast tumor copy number aberration phenotypes and genomic instability

1 reference

12 December 2020

The prognostic implication of the basal-like (cyclin E high/p27 low/p53+/glomeruloid-microvascular-proliferation+) phenotype of BRCA1-related breast cancer

1 reference

12 December 2020

Immunohistochemical characteristics defined by tissue microarray of hereditary breast cancer not attributable to BRCA1 or BRCA2 mutations: differences from breast carcinomas arising in BRCA1 and BRCA2 mutation carriers.

1 reference

12 December 2020

A predictor based on the somatic genomic changes of the BRCA1/BRCA2 breast cancer tumors identifies the non-BRCA1/BRCA2 tumors with BRCA1 promoter hypermethylation

1 reference

12 December 2020

Distinct somatic genetic changes associated with tumor progression in carriers of BRCA1 and BRCA2 germ-line mutations

1 reference

12 December 2020

Phenotype-genotype correlation in familial breast cancer

1 reference

12 December 2020

Subtypes of familial breast tumours revealed by expression and copy number profiling

1 reference

12 December 2020

MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype

1 reference

12 December 2020

Re: Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer

1 reference

12 December 2020

Cancer risks and mortality in heterozygous ATM mutation carriers

1 reference

12 December 2020

Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

1 reference

12 December 2020

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

1 reference

12 December 2020

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer

1 reference

12 December 2020

Prediction of BRCA1 status in patients with breast cancer using estrogen receptor and basal phenotype

1 reference

12 December 2020

Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer risk

1 reference

12 December 2020

RAD50 and NBS1 are breast cancer susceptibility genes associated with genomic instability

1 reference

12 December 2020

Localization of a breast cancer susceptibility gene, BRCA2, to chromosome 13q12-13.

1 reference

12 December 2020

Array comparative genomic hybridization analysis of genomic alterations in breast cancer subtypes

1 reference

12 December 2020

BRCA1 basal-like breast cancers originate from luminal epithelial progenitors and not from basal stem cells

1 reference

12 December 2020

Whole exome sequencing suggests much of non-BRCA1/BRCA2 familial breast cancer is due to moderate and low penetrance susceptibility alleles

1 reference

12 December 2020

Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases.

1 reference

12 December 2020

Novel patterns of genome rearrangement and their association with survival in breast cancer

1 reference

12 December 2020

BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage

1 reference

12 December 2020

Germline mutations in RAD51D confer susceptibility to ovarian cancer

1 reference

12 December 2020

Stem cells and breast cancer: A field in transit

1 reference

12 December 2020

Familial concordance of breast cancer pathology as an indicator of genotype in multiple-case families

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12 December 2020

Mutational processes molding the genomes of 21 breast cancers

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12 December 2020

Genome-wide linkage scan reveals three putative breast-cancer-susceptibility loci

1 reference

12 December 2020

Complex landscapes of somatic rearrangement in human breast cancer genomes

1 reference

12 December 2020

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

1 reference

12 December 2020

The pathology of familial breast cancer: predictive value of immunohistochemical markers estrogen receptor, progesterone receptor, HER-2, and p53 in patients with mutations in BRCA1 and BRCA2.

1 reference

12 December 2020

Comprehensive molecular portraits of human breast tumours

1 reference

12 December 2020

Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancer

1 reference

12 December 2020

Characterization of Familial Non-BRCA1/2 Breast Tumors by Loss of Heterozygosity and Immunophenotyping

1 reference

12 December 2020

Deregulated miRNAs in hereditary breast cancer revealed a role for miR-30c in regulating KRAS oncogene

1 reference

12 December 2020

MicroRNA gene expression deregulation in human breast cancer

1 reference

12 December 2020

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

1 reference

12 December 2020

Frequent somatic mutations of GATA3 in non-BRCA1/BRCA2 familial breast tumors, but not in BRCA1-, BRCA2- or sporadic breast tumors.

1 reference

12 December 2020

Novel indications for BRCA1 screening using individual clinical and morphological features

1 reference

12 December 2020

Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization

1 reference

12 December 2020

Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer

1 reference

12 December 2020

A common coding variant in CASP8 is associated with breast cancer risk

1 reference

12 December 2020

Incidence of gastric cancer and breast cancer in CDH1 (E-cadherin) mutation carriers from hereditary diffuse gastric cancer families

1 reference

12 December 2020

An integrative hypothesis about the origin and development of sporadic and familial breast cancer subtypes

1 reference

12 December 2020

Gene-Expression Profiles in Hereditary Breast Cancer

1 reference

12 December 2020

CK8/18 expression, the basal phenotype, and family history in identifying BRCA1-associated breast cancer in the Ontario site of the breast cancer family registry

1 reference

12 December 2020

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

1 reference

12 December 2020

High frequency of TP53 mutation in BRCA1 and sporadic basal-like carcinomas but not in BRCA1 luminal breast tumors

1 reference

12 December 2020

Expression profiling of familial breast cancers demonstrates higher expression of FGFR2 in BRCA2-associated tumors

1 reference

12 December 2020

CGH analysis of familial non-BRCA1/BRCA2 breast tumors and mutation screening of a candidate locus on chromosome 17q11.2-12

1 reference

12 December 2020

Genomic signature of BRCA1 deficiency in sporadic basal-like breast tumors

1 reference

12 December 2020

EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer

1 reference

12 December 2020

BRCA1 dysfunction in sporadic basal-like breast cancer

1 reference

12 December 2020

Large-scale genotyping identifies 41 new loci associated with breast cancer risk

1 reference

12 December 2020

The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2

1 reference

12 December 2020

Comparison of genomic abnormalities between BRCAX and sporadic breast cancers studied by comparative genomic hybridization

1 reference

12 December 2020

Mutational analysis of telomere genes in BRCA1/2-negative breast cancer families with very short telomeres

1 reference

12 December 2020

Genomic profiling of breast tumours in relation to BRCA abnormalities and phenotypes

1 reference

12 December 2020

Prediction of BRCA1-association in hereditary non-BRCA1/2 breast carcinomas with array-CGH

1 reference

12 December 2020

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

1 reference

12 December 2020

Peutz-Jeghers syndrome: genetic screening

1 reference

12 December 2020

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

1 reference

12 December 2020

Molecular classification of familial non-BRCA1/BRCA2 breast cancer

1 reference

12 December 2020

BRCA1 and BRCA2: different roles in a common pathway of genome protection

1 reference

12 December 2020

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

1 reference

12 December 2020

10.1007/S00439-013-1299-Y

Identifiers

DOI

1 reference

PubMed ID

23552954

Dimensions Publication ID

28 August 2017

0 references

1 reference

PubMed ID

23552954