(Q38099065)

28 August 2017

Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma (English)

1 reference

28 August 2017

2

Christian Haass

0 references

author name string

Eva Bentmann

series ordinal

1

1 reference

PubMed ID

23587065

28 August 2017

Dorothee Dormann

series ordinal

3

1 reference

PubMed ID

23587065

28 August 2017

language of work or name

English

0 references

publication date

9 May 2013

1 reference

28 August 2017

1 reference

28 August 2017

280

1 reference

28 August 2017

18

1 reference

28 August 2017

4348-4370

1 reference

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

28 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A new subtype of frontotemporal lobar degeneration with FUS pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Misregulated RNA processing in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

RNA processing pathways in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Tar DNA binding protein of 43 kDa (TDP-43), 14-3-3 proteins and copper/zinc superoxide dismutase (SOD1) interact to modulate NFL mRNA stability. Implications for altered RNA processing in amyotrophic lateral sclerosis (ALS).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Requirements for stress granule recruitment of fused in sarcoma (FUS) and TAR DNA-binding protein of 43 kDa (TDP-43)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Regulated protein aggregation: stress granules and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The molecular basis of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

21 January 2018

Frontotemporal dementia

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 A315T mutation in familial motor neuron disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 mutations in familial and sporadic amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 and FUS in amyotrophic lateral sclerosis and frontotemporal dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

FUS pathology in basophilic inclusion body disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A C9orf72 promoter repeat expansion in a Flanders-Belgian cohort with disorders of the frontotemporal lobar degeneration-amyotrophic lateral sclerosis spectrum: a gene identification study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Characterization and functional implications of the RNA binding properties of nuclear factor TDP-43, a novel splicing regulator of CFTR exon 9

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The multiple roles of TDP-43 in pre-mRNA processing and gene expression regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 promotes microRNA biogenesis as a component of the Drosha and Dicer complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Characterization of an RNA granule from developing brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Local RNA translation at the synapse and in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Functional mapping of the interaction between TDP-43 and hnRNP A2 in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Global analysis of TDP-43 interacting proteins reveals strong association with RNA splicing and translation machinery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Prion-like disorders: blurring the divide between transmissibility and infectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Interaction with polyglutamine aggregates reveals a Q/N-rich domain in TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Implications of the prion-related Q/N domains in TDP-43 and FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Amyotrophic lateral sclerosis-associated proteins TDP-43 and FUS/TLS function in a common biochemical complex to co-regulate HDAC6 mRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Cytoplasmic mislocalization of TDP-43 is toxic to neurons and enhanced by a mutation associated with familial amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43-mediated neuron loss in vivo requires RNA-binding activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Transgenic rat model of neurodegeneration caused by mutation in the TDP gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowth

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Fusion of CHOP to a novel RNA-binding protein in human myxoid liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Position-dependent FUS-RNA interactions regulate alternative splicing events and transcriptions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Kinesin transports RNA: isolation and characterization of an RNA-transporting granule

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The RNA binding protein TLS is translocated to dendritic spines by mGluR5 activation and regulates spine morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Myosin-Va facilitates the accumulation of mRNA/protein complex in dendritic spines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Fused in sarcoma (FUS): an oncogene goes awry in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A novel effector domain from the RNA-binding protein TLS or EWS is required for oncogenic transformation by CHOP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Identification of an RNA binding specificity for the potential splicing factor TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Domain architectures and characterization of an RNA-binding protein, TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Nuclear localization sequence of FUS and induction of stress granules by ALS mutants.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Nuclear transport impairment of amyotrophic lateral sclerosis-linked mutations in FUS/TLS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Intracellular localization and splicing regulation of FUS/TLS are variably affected by amyotrophic lateral sclerosis-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Structural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

FUS-NLS/Transportin 1 complex structure provides insights into the nuclear targeting mechanism of FUS and the implications in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mutant FUS proteins that cause amyotrophic lateral sclerosis incorporate into stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stress granules: sites of mRNA triage that regulate mRNA stability and translatability

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stress granules: the Tao of RNA triage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stress granules and processing bodies are dynamically linked sites of mRNP remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

21 January 2018

On track with P-bodies

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Sequestration of TRAF2 into stress granules interrupts tumor necrosis factor signaling under stress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Formation of stress granules inhibits apoptosis by suppressing stress-responsive MAPK pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Eukaryotic stress granules: the ins and outs of translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TOPs and their regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Translational regulation of gene expression during conditions of cell stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Translational coregulation of 5'TOP mRNAs by TIA-1 and TIAR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

ZBP1 regulates mRNA stability during cellular stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

BCL-2 translation is mediated via internal ribosome entry during cell stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Translational induction of VEGF internal ribosome entry site elements during the early response to ischemic stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Cytoplasmic ribonucleoprotein (RNP) bodies and their relationship to GW/P bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mammalian stress granules and processing bodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

How do viruses interact with stress-associated RNA granules?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

MicroRNA responses and stress granule formation modulate the DNA damage response.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Hydrogen peroxide induces stress granule formation independent of eIF2α phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Translation suppression promotes stress granule formation and cell survival in response to cold shock

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Functional characterization of IRESes by an inhibitor of the RNA helicase eIF4A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stimulation of mammalian translation initiation factor eIF4A activity by a small molecule inhibitor of eukaryotic translation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Inhibition of ribosome recruitment induces stress granule formation independently of eukaryotic initiation factor 2alpha phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Uncoupling stress granule assembly and translation initiation inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A functional RNAi screen links O-GlcNAc modification of ribosomal proteins to stress granule and processing body assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The role of posttranslational modifications in the assembly of stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Methylation regulates the intracellular protein-protein and protein-RNA interactions of FMRP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The cold-inducible RNA-binding protein migrates from the nucleus to cytoplasmic stress granules by a methylation-dependent mechanism and acts as a translational repressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Arginine methylation by PRMT1 regulates nuclear-cytoplasmic localization and toxicity of FUS/TLS harbouring ALS-linked mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mammalian Staufen 1 is recruited to stress granules and impairs their assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stress granule assembly is mediated by prion-like aggregation of TIA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Dynamic shuttling of TIA-1 accompanies the recruitment of mRNA to mammalian stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

mRNA cycles through hypoxia-induced stress granules in live Drosophila embryonic muscles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Fragile X mental retardation protein shifts between polyribosomes and stress granules after neuronal injury by arsenite stress or in vivo hippocampal electrode insertion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Prolonged translation arrest in reperfused hippocampal cornu Ammonis 1 is mediated by stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Persistent redistribution of poly-adenylated mRNAs correlates with translation arrest and cell death following global brain ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Convergence of stress granules and protein aggregates in hippocampal cornu ammonis 1 at later reperfusion following global brain ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Oxidative stress in ALS: key role in motor neuron injury and therapeutic target

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The neurovascular link in health and disease: molecular mechanisms and therapeutic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Chronic traumatic encephalopathy: a potential late effect of sport-related concussive and subconcussive head trauma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Head injury and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

ALS in Italian professional soccer players: the risk is still present and could be soccer-specific.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Infectious agents and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Neurodegeneration the RNA way

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 is recruited to stress granules in conditions of oxidative insult.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TAR DNA-binding protein 43 (TDP-43) regulates stress granule dynamics via differential regulation of G3BP and TIA-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Roles of ataxin-2 in pathological cascades mediated by TAR DNA-binding protein 43 (TDP-43) and Fused in Sarcoma (FUS)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Endogenous TDP-43, but not FUS, contributes to stress granule assembly via G3BP

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Cell-free formation of RNA granules: low complexity sequence domains form dynamic fibers within hydrogels

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The multifunctional FUS, EWS and TAF15 proto-oncoproteins show cell type-specific expression patterns and involvement in cell spreading and stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Gene expression responses to FUS, EWS, and TAF15 reduction and stress granule sequestration analyses identifies FET-protein non-redundant functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The TET family of proteins: functions and roles in disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A yeast functional screen predicts new candidate ALS disease genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mutational analysis reveals the FUS homolog TAF15 as a candidate gene for familial amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Evaluating the role of the FUS/TLS-related gene EWSR1 in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Domains involved in TAF15 subcellular localisation: dependence on cell type and ongoing transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Structural and functional analysis of ataxin-2 and ataxin-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 and its Drosophila homolog, ATX2, physically assemble with polyribosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Moderate expansion of a normally biallelic trinucleotide repeat in spinocerebellar ataxia type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 repeat-length variation and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Expanded ATXN2 CAG repeat size in ALS identifies genetic overlap between ALS and SCA2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 interacts with FUS and intermediate-length polyglutamine expansions enhance FUS-related pathology in amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Ataxin-2 interacts with the DEAD/H-box RNA helicase DDX6 and interferes with P-bodies and stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Hepatitis C virus hijacks P-body and stress granule components around lipid droplets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

P bodies promote stress granule assembly in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

An integrative approach to gain insights into the cellular function of human ataxin-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Spinal muscular atrophy: the role of SMN in axonal mRNA regulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Identification and characterization of a spinal muscular atrophy-determining gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Survival motor neuron gene transcript analysis in muscles from spinal muscular atrophy patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Correlation between severity and SMN protein level in spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The survival motor neuron protein in spinal muscular atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Survival motor neuron protein facilitates assembly of stress granules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

SMN deficiency reduces cellular ability to form stress granules, sensitizing cells to stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Molecular Mechanisms in Amyotrophic Lateral Sclerosis: The Role of Angiogenin, a Secreted RNase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Motoneurons secrete angiogenin to induce RNA cleavage in astroglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Stress induces tRNA cleavage by angiogenin in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Angiogenin-induced tRNA-derived stress-induced RNAs promote stress-induced stress granule assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Amyotrophic lateral sclerosis-linked mutant SOD1 sequesters Hu antigen R (HuR) and TIA-1-related protein (TIAR): implications for impaired post-transcriptional regulation of vascular endothelial growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Accumulation of mutant huntingtin fragments in aggresome-like inclusion bodies as a result of insufficient protein degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Expression of TDP-43 C-terminal Fragments in Vitro Recapitulates Pathological Features of TDP-43 Proteinopathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Juvenile ALS with basophilic inclusions is a FUS proteinopathy with FUS mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

RNA stimulates aggregation of microtubule-associated protein tau into Alzheimer-like paired helical filaments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

RNA molecules stimulate prion protein conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Inhibition of the ubiquitin-proteasome system induces stress granule formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The seeds of neurodegeneration: prion-like spreading in ALS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A seeding reaction recapitulates intracellular formation of Sarkosyl-insoluble transactivation response element (TAR) DNA-binding protein-43 inclusions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

An ALS-associated mutation affecting TDP-43 enhances protein aggregation, fibril formation and neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Regulation of TDP-43 aggregation by phosphorylation and p62/SQSTM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

p62 Is a common component of cytoplasmic inclusions in protein aggregation diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Autophagy gone awry in neurodegenerative diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 regulates its mRNA levels through a negative feedback loop

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Selective neuronal vulnerability in neurodegenerative diseases: from stressor thresholds to degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Chronic Traumatic Encephalopathy in Athletes: Progressive Tauopathy After Repetitive Head Injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Games played by rogue proteins in prion disorders and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

FUS-immunoreactive intranuclear inclusions in neurodegenerative disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

RNA-binding protein TLS is a major nuclear aggregate-interacting protein in huntingtin exon 1 with expanded polyglutamine-expressing cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

The RNA-binding protein FUS/TLS is a common aggregate-interacting protein in polyglutamine diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TARDBP mutations in motoneuron disease with frontotemporal lobar degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Mutation within TARDBP leads to frontotemporal dementia without motor neuron disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TARDBP 3'-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43 immunoreactivity in hippocampal sclerosis and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

TDP-43: a new player on the AD field?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Colocalization of transactivation-responsive DNA-binding protein 43 and huntingtin in inclusions of Huntington disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

Abnormal SMN1 gene copy number is a susceptibility factor for amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12287

21 January 2018

Identifiers

DOI

10.1111/FEBS.12287

1 reference

28 August 2017

1 reference

PubMed ID

23587065