(Q38099615)

28 August 2017

Immunometabolic role of long-chain omega-3 fatty acids in obesity-induced inflammation (English)

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28 August 2017

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Michael R Flock

1

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28 August 2017

Connie J Rogers

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2

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28 August 2017

K Sandeep Prabhu

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3

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28 August 2017

Penny M Kris-Etherton

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4

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28 August 2017

1 September 2013

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Diabetes - Metabolism: Research and Reviews

28 August 2017

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28 August 2017

29

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28 August 2017

6

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28 August 2017

431-445

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Macrophage-mediated inflammation in metabolic disease

28 August 2017

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Resolvins: anti-inflammatory and proresolving mediators derived from omega-3 polyunsaturated fatty acids.

21 January 2018

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Efficiency of conversion of alpha-linolenic acid to long chain n-3 fatty acids in man.

21 January 2018

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Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements

21 January 2018

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Conversion of alpha-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women.

21 January 2018

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Effects of combined dietary supplementation on oxidative and inflammatory status in dyslipidemic subjects

21 January 2018

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Influence of very long-chain n-3 fatty acids on plasma markers of inflammation in middle-aged men.

21 January 2018

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Dietary n-3 fatty acids and therapy for rheumatoid arthritis

21 January 2018

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Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease

21 January 2018

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Omega-3 fatty acids in critical illness

21 January 2018

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Fish oil supplementation in type 2 diabetes: a quantitative systematic review

21 January 2018

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Omega-3 polyunsaturated fatty acid and insulin sensitivity: a meta-analysis of randomized controlled trials

21 January 2018

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Beneficial effects of long-chain n-3 fatty acids included in an energy-restricted diet on insulin resistance in overweight and obese European young adults.

21 January 2018

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An oily fish diet increases insulin sensitivity compared to a red meat diet in young iron-deficient women

21 January 2018

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Effects of n-3 polyunsaturated fatty acids in subjects with nonalcoholic fatty liver disease

21 January 2018

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Prevention of insulin resistance by n-3 polyunsaturated fatty acids

21 January 2018

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N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials

21 January 2018

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Association between omega-3 fatty acid supplementation and risk of major cardiovascular disease events: a systematic review and meta-analysis

21 January 2018

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Efficacy of omega-3 fatty acid supplements (eicosapentaenoic acid and docosahexaenoic acid) in the secondary prevention of cardiovascular disease: a meta-analysis of randomized, double-blind, placebo-controlled trials

21 January 2018

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Omega-3 fatty acids in high-risk cardiovascular patients: a meta-analysis of randomized controlled trials

21 January 2018

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Omega-3 dietary supplements and the risk of cardiovascular events: a systematic review.

21 January 2018

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Effect of fish oil on arrhythmias and mortality: systematic review

21 January 2018

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Towards establishing dietary reference intakes for eicosapentaenoic and docosahexaenoic acids.

21 January 2018

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Sudden death prevention in patients with advanced ventricular dysfunction

21 January 2018

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Benefits of fish oil supplementation in hyperlipidemia: a systematic review and meta-analysis

21 January 2018

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Meta-analysis of the effects of n-3 polyunsaturated fatty acids on lipoproteins and other emerging lipid cardiovascular risk markers in patients with type 2 diabetes

21 January 2018

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Blood pressure response to fish oil supplementation: metaregression analysis of randomized trials

21 January 2018

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Blood pressure and vascular reactivity changes in spontaneously hypertensive rats fed fish oil

21 January 2018

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Fish oil feeding selectively attenuates contractile responses to noradrenaline and electrical stimulation in the perfused mesenteric resistance vessels of spontaneously hypertensive rats

21 January 2018

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Fish oil improves arterial compliance in non-insulin-dependent diabetes mellitus

21 January 2018

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Ventricular arrhythmias in first 12 hours of acute myocardial infarction. Natural history study

21 January 2018

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Clinical prevention of sudden cardiac death by n-3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils

21 January 2018

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n-3 Fatty acids and ventricular arrhythmias in patients with ischaemic heart disease and implantable cardioverter defibrillators.

21 January 2018

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Immediate effects of n-3 fatty acid infusion on the induction of sustained ventricular tachycardia.

21 January 2018

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Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial

21 January 2018

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Inflammatory mechanisms in obesity

21 January 2018

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The phosphatidylserine receptor: a crucial molecular switch?

21 January 2018

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Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

21 January 2018

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Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

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Mechanisms of obesity and related pathologies: the macro- and microcirculation of adipose tissue

21 January 2018

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Adipokines: inflammation and the pleiotropic role of white adipose tissue

21 January 2018

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Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

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Connecting type 1 and type 2 diabetes through innate immunity

21 January 2018

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

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Phagocyte partnership during the onset and resolution of inflammation.

21 January 2018

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Exploring the full spectrum of macrophage activation

21 January 2018

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Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators

21 January 2018

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Neutrophil function: from mechanisms to disease

21 January 2018

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Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death

21 January 2018

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Insulin sensitivity: modulation by nutrients and inflammation

21 January 2018

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Macrophages, meta-inflammation, and immuno-metabolism.

21 January 2018

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Type 2 diabetes as an inflammatory disease

21 January 2018

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Tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes is accompanied by a loss of insulin receptor substrate-1 and GLUT4 expression without a loss of insulin receptor-mediated signal transduction.

21 January 2018

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Tumor necrosis factor-alpha suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-kappaB activation by TNF-alpha is obligatory

21 January 2018

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Cytokine signaling in 2002: new surprises in the Jak/Stat pathway

21 January 2018

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SOCS proteins, cytokine signalling and immune regulation

21 January 2018

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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

21 January 2018

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

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Overexpression of suppressor of cytokine signaling 3 in adipose tissue causes local but not systemic insulin resistance

21 January 2018

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The emerging genetics of type 2 diabetes

21 January 2018

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Genetics of gene expression and its effect on disease

21 January 2018

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The role of adipose tissue in mediating the beneficial effects of dietary fish oil

21 January 2018

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Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

21 January 2018

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Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids

21 January 2018

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Modulation of pattern recognition receptor-mediated inflammation and risk of chronic diseases by dietary fatty acids

21 January 2018

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Polyunsaturated eicosapentaenoic acid displaces proteins from membrane rafts by altering raft lipid composition.

21 January 2018

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Dietary docosahexaenoic acid suppresses T cell protein kinase C theta lipid raft recruitment and IL-2 production

21 January 2018

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Docosahexaenoic acid alters the size and distribution of cell surface microdomains

21 January 2018

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Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells

21 January 2018

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Membrane lipid raft organization is uniquely modified by n-3 polyunsaturated fatty acids

21 January 2018

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Effect of ω-3 polyunsaturated fatty acid on toll-like receptors in patients with severe multiple trauma.

21 January 2018

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Anti-inflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective

21 January 2018

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Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

21 January 2018

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A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma

21 January 2018

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A nuclear receptor corepressor transcriptional checkpoint controlling activator protein 1-dependent gene networks required for macrophage activation

21 January 2018

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Nuclear receptor transrepression pathways that regulate inflammation in macrophages and T cells

21 January 2018

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Docosahexaenoic acid decreases phospholipase A2 activity in the neurites/nerve growth cones of PC12 cells

21 January 2018

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Prostaglandins and leukotrienes: advances in eicosanoid biology

21 January 2018

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Resolution of inflammation: the beginning programs the end

21 January 2018

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Novel functional sets of lipid-derived mediators with antiinflammatory actions generated from omega-3 fatty acids via cyclooxygenase 2-nonsteroidal antiinflammatory drugs and transcellular processing

21 January 2018

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Lipid mediator class switching during acute inflammation: signals in resolution.

21 January 2018

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Specialized proresolving mediator targets for RvE1 and RvD1 in peripheral blood and mechanisms of resolution

21 January 2018

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Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products

21 January 2018

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Neuroprotectin D1: a docosahexaenoic acid-derived docosatriene protects human retinal pigment epithelial cells from oxidative stress

21 January 2018

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Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

21 January 2018

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Resolvin E1 and protectin D1 activate inflammation-resolution programmes

21 January 2018

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In obesity and weight loss, all roads lead to the mighty macrophage

21 January 2018

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Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1

21 January 2018

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Resolvin E1 receptor activation signals phosphorylation and phagocytosis

21 January 2018

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Resolvin E1 selectively interacts with leukotriene B4 receptor BLT1 and ChemR23 to regulate inflammation.

21 January 2018

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Resolvin D1 binds human phagocytes with evidence for proresolving receptors

21 January 2018

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Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors

21 January 2018

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Diabetes: New conductors for the peroxisome proliferator-activated receptor γ (PPARγ) orchestra

21 January 2018

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Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance

21 January 2018

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Novel approach to treat insulin resistance, type 2 diabetes, and the metabolic syndrome: simultaneous activation of PPARalpha, PPARgamma, and PPARdelta

21 January 2018

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mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

21 January 2018

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Fat poetry: a kingdom for PPAR gamma

21 January 2018

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The role of inflammation and macrophage accumulation in the development of obesity-induced type 2 diabetes mellitus and the possible therapeutic effects of long-chain n-3 PUFA.

21 January 2018

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Peroxisome proliferator-activated receptor (PPAR)alpha activation increases adiponectin receptors and reduces obesity-related inflammation in adipose tissue: comparison of activation of PPARalpha, PPARgamma, and their combination

21 January 2018

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Adiponectin primes human monocytes into alternative anti-inflammatory M2 macrophages

21 January 2018

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Adiponectin promotes macrophage polarization toward an anti-inflammatory phenotype

21 January 2018

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Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

21 January 2018

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Cardiovascular disease-related genes and regulation by diet

21 January 2018

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GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects

21 January 2018

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Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases

21 January 2018

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Alternative macrophage activation and metabolism

21 January 2018

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The impact of common gene variants on the response of biomarkers of cardiovascular disease (CVD) risk to increased fish oil fatty acids intakes

21 January 2018

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n-3 Fatty acids from fish or fish-oil supplements, but not alpha-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review

21 January 2018

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7 January 2021

Omega-3 polyunsaturated fatty acids and inflammatory processes: nutrition or pharmacology?

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7 January 2021

Anti-inflammatory and cardioprotective effects of n-3 polyunsaturated fatty acids and plant sterols in hyperlipidemic individuals

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7 January 2021

Dietary intake of differently fed salmon; the influence on markers of human atherosclerosis

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7 January 2021

C-reactive protein and n-3 fatty acids in patients with a previous myocardial infarction: a placebo-controlled randomized study

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7 January 2021

The effect of dietary n-3 fatty acids on serum concentrations of C-reactive protein: a dose-response study

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7 January 2021

Long-term effect of omega-3 fatty acid supplementation in active rheumatoid arthritis. A 12-month, double-blind, controlled study

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7 January 2021

Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production

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7 January 2021

Treatment of ulcerative colitis with fish oil n--3-omega-fatty acid: an open trial.

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7 January 2021

Therapeutic potential of fish oil in the treatment of ulcerative colitis

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7 January 2021

ω-3 Fatty acid–based lipid infusion in patients with chronic plaque psoriasis: Results of a double-blind, randomized, placebo-controlled, multicenter trial

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7 January 2021

Omega 3 polyunsaturated fatty acid constituents of fish oil and the management of skin inflammatory and scaly disorders

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7 January 2021

Specific insulin sensitivity and leptin responses to a nutritional treatment of obesity via a combination of energy restriction and fatty fish intake

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7 January 2021

The impact of long chain n-3 polyunsaturated fatty acid supplementation on inflammation, insulin sensitivity and CVD risk in a group of overweight women with an inflammatory phenotype

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7 January 2021

Fish oil and cardiovascular disease: lipids and arterial function

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7 January 2021

Prevention of Sudden Cardiac Death by Dietary Pure ω-3 Polyunsaturated Fatty Acids in Dogs

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7 January 2021

Inflammation and insulin resistance

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7 January 2021

SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice

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7 January 2021

Mechanisms of action of (n-3) fatty acids

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7 January 2021

Dietary (n-3) polyunsaturated fatty acids remodel mouse T-cell lipid rafts.

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7 January 2021

Identifiers

DOI

10.1002/DMRR.2414

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28 August 2017

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