(Q38100745)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

The significance of heat shock proteins in breast cancer therapy (English)

1 reference

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29 February 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

3

Kadri Altundag

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

author name string

Burcin Halacli

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

publication date

20 April 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

volume

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

575

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23606238%20AND%20SRC:MED&resulttype=core&format=json

Heat shock proteins in cancer: diagnostic, prognostic, predictive, and treatment implications

29 February 2020

cites work

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Role of the major heat shock proteins as molecular chaperones

21 January 2018

1 reference

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Heat shock, stress proteins, chaperones, and proteotoxicity

21 January 2018

1 reference

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Protein folding in the cell

21 January 2018

1 reference

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Protein folding in the cytosol: chaperonin-dependent and -independent mechanisms

21 January 2018

1 reference

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Disassembly of transcriptional regulatory complexes by molecular chaperones

21 January 2018

1 reference

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Hsp90 as a capacitor of phenotypic variation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

HSP90 and the chaperoning of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Increased risk of malignant progression in benign proliferating breast lesions defined by expression of heat shock protein 27

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Heat shock protein as molecular targets for breast cancer therapeutics

21 January 2018

1 reference

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Upregulated HSP27 in human breast cancer cells reduces Herceptin susceptibility by increasing Her2 protein stability

21 January 2018

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Hsp27 overexpression inhibits doxorubicin-induced apoptosis in human breast cancer cells.

21 January 2018

1 reference

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Hsp27 participates in the maintenance of breast cancer stem cells through regulation of epithelial-mesenchymal transition and nuclear factor-κB.

21 January 2018

1 reference

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Blocking tumor cell migration and invasion with biphenyl isoxazole derivative KRIBB3, a synthetic molecule that inhibits Hsp27 phosphorylation

21 January 2018

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Downregulation of Hsp27 (HSPB1) in MCF-7 human breast cancer cells induces upregulation of PTEN.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Sulphoraphane, a naturally occurring isothiocyanate induces apoptosis in breast cancer cells by targeting heat shock proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Imatinib reverses doxorubicin resistance by affecting activation of STAT3-dependent NF-κB and HSP27/p38/AKT pathways and by inhibiting ABCB1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Inhibition of heat shock protein (Hsp) 27 potentiates the suppressive effect of Hsp90 inhibitors in targeting breast cancer stem-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Quercetin inhibits heat shock protein induction but not heat shock factor DNA-binding in human breast carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Selective depletion of heat shock protein 70 (Hsp70) activates a tumor-specific death program that is independent of caspases and bypasses Bcl-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Expression of inducible Hsp70 enhances the proliferation of MCF-7 breast cancer cells and protects against the cytotoxic effects of hyperthermia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Immune response to p53 is dependent upon p53/HSP70 complexes in breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Extracellular heat shock protein (Hsp)70 and Hsp90α assist in matrix metalloproteinase-2 activation and breast cancer cell migration and invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Secretory heat-shock protein as a dendritic cell-targeting molecule: a new strategy to enhance the potency of genetic vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

N-terminally fusion of Her2/neu to HSP70 decreases efficiency of Her2/neu DNA vaccine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

High HSP90 expression is associated with decreased survival in breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Expression and roles of heat shock proteins in human breast cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Cell surface Cdc37 participates in extracellular HSP90 mediated cancer cell invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Expression of hsp90 and cyclin D1 in human breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Hsp90 rescues PTK6 from proteasomal degradation in breast cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Short-hairpin RNA-mediated Heat shock protein 90 gene silencing inhibits human breast cancer cell growth in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Hsp90α/β associates with the GSK3β/axin1/phospho-β-catenin complex in the human MCF-7 epithelial breast cancer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Identification and structural characterization of the ATP/ADP-binding site in the Hsp90 molecular chaperone

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Design, synthesis, and evaluation of small molecule Hsp90 probes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Geldanamycin-induced down-regulation of ErbB2 from the plasma membrane is clathrin dependent but proteasomal activity independent

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Immunoconjugates of geldanamycin and anti-HER2 monoclonal antibodies: antiproliferative activity on human breast carcinoma cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Inhibiting the HSP90 chaperone destabilizes macrophage migration inhibitory factor and thereby inhibits breast tumor progression

21 January 2018

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HSP90 inhibitor antagonizing MIF: The specifics of pleiotropic cancer drug candidates

21 January 2018

1 reference

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Effects of HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin (17-AAG) on NEU/HER2 overexpressing mammary tumours in MMTV-NEU-NT mice monitored by Magnetic Resonance Spectroscopy

21 January 2018

1 reference

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HSP90 inhibition is effective in breast cancer: a phase II trial of tanespimycin (17-AAG) plus trastuzumab in patients with HER2-positive metastatic breast cancer progressing on trastuzumab.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

A phase II study of 17-allylamino-17-demethoxygeldanamycin in metastatic or locally advanced, unresectable breast cancer

21 January 2018

1 reference

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AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies

21 January 2018

1 reference

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Population pharmacokinetic analysis of 17-dimethylaminoethylamino-17-demethoxygeldanamycin (17-DMAG) in adult patients with solid tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12032-013-0575-Y

Heat shock protein expression and drug resistance in breast cancer patients treated with induction chemotherapy

21 January 2018

1 reference

12 December 2020

Pharmacology and anti-tumor activity of RWJ67657, a novel inhibitor of p38 mitogen activated protein kinase

1 reference

12 December 2020

Correlation of heat shock protein (HSP70) expression with cell proliferation (MIB1), estrogen receptors (ER) and clinicopathological variables in invasive ductal breast carcinomas

1 reference

12 December 2020

A phase I trial of twice-weekly 17-allylamino-demethoxy-geldanamycin in patients with advanced cancer

1 reference

12 December 2020

A phase I dose-escalation trial of trastuzumab and alvespimycin hydrochloride (KOS-1022; 17 DMAG) in the treatment of advanced solid tumors

1 reference

12 December 2020

Enhanced immunity by NeuEDhsp70 DNA vaccine Is needed to combat an aggressive spontaneous metastatic breast cancer

1 reference

12 December 2020

Geldanamycin destabilizes HER2 tyrosine kinase and suppresses Wnt/beta-catenin signaling in HER2 overexpressing human breast cancer cells

1 reference

12 December 2020

Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent

1 reference

12 December 2020

Heat shock protein 70 is required for the survival of cancer cells.

1 reference

12 December 2020

The small heat shock protein hsp27 is correlated with growth and drug resistance in human breast cancer cell lines.

1 reference

12 December 2020

Leptin increases HER2 protein levels through a STAT3-mediated up-regulation of Hsp90 in breast cancer cells

1 reference

12 December 2020

Enhancement of DNA vaccine potency by linkage of antigen gene to an HSP70 gene

1 reference

12 December 2020

Geldanamycin, a new antibiotic

1 reference

12 December 2020