(Q38104710)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

title

Systems biology of the functional and dysfunctional endothelium (English)

1 reference

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29 February 2020

0 references

6

1 reference

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29 February 2020

author name string

Jennifer Frueh

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Nataly Maimari

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Takayuki Homma

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Sandra M Bovens

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Ryan M Pedrigi

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

Rob Krams

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

publication date

6 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

published in

Cardiovascular Research

1 reference

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29 February 2020

volume

99

1 reference

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29 February 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

29 February 2020

page(s)

334-341

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

Atheroprotective mechanisms of shear stress-regulated microRNAs.

29 February 2020

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Vulnerable plaque: the pathology of unstable coronary lesions

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Mechanotransduction in vascular physiology and atherogenesis

21 January 2018

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Hemodynamic shear stress and the endothelium in cardiovascular pathophysiology

21 January 2018

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Vascular endothelial responses to altered shear stress: pathologic implications for atherosclerosis

21 January 2018

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The critical role of hemodynamics in the development of cerebral vascular disease

21 January 2018

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Role of endothelial shear stress in the natural history of coronary atherosclerosis and vascular remodeling: molecular, cellular, and vascular behavior

21 January 2018

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Shear stress and plaque development

21 January 2018

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Extension of increased atherosclerotic wall thickness into high shear stress regions is associated with loss of compensatory remodeling.

21 January 2018

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Large variations in absolute wall shear stress levels within one species and between species

21 January 2018

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Heterogeneity of tensile strength and matrix metalloproteinase activity in the wall of abdominal aortic aneurysms.

21 January 2018

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OCT assessment of thin-cap fibroatheroma distribution in native coronary arteries.

21 January 2018

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A three-vessel virtual histology intravascular ultrasound analysis of frequency and distribution of thin-cap fibroatheromas in patients with acute coronary syndrome or stable angina pectoris.

21 January 2018

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Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype

21 January 2018

1 reference

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Shear stress-induced changes in atherosclerotic plaque composition are modulated by chemokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Rapamycin modulates the eNOS vs. shear stress relationship

21 January 2018

1 reference

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Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress.

21 January 2018

1 reference

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Pathological findings at bifurcation lesions: the impact of flow distribution on atherosclerosis and arterial healing after stent implantation

21 January 2018

1 reference

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Prediction of the localization of high-risk coronary atherosclerotic plaques on the basis of low endothelial shear stress: an intravascular ultrasound and histopathology natural history study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives

21 January 2018

1 reference

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Role of hemodynamic shear stress in cardiovascular disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

The shear stress of it all: the cell membrane and mechanochemical transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Risk stratification of individual coronary lesions using local endothelial shear stress: a new paradigm for managing coronary artery disease

21 January 2018

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Mechanotransduction and the glycocalyx

21 January 2018

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Shear stress biology of the endothelium

21 January 2018

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Unraveling human complexity and disease with systems biology and personalized medicine

21 January 2018

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Comparative systems biology across an evolutionary gradient within the Shewanella genus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

A framework for evolutionary systems biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Microbial systems biology: new frontiers open to predictive microbiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Beyond reductionism: metabolic circularity as a guiding vision for a real biology of systems.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Differential endothelial cell gene expression by African Americans versus Caucasian Americans: a possible contribution to health disparity in vascular disease and cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

KLF2-induced actin shear fibers control both alignment to flow and JNK signaling in vascular endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Effect of fluid flow-induced shear stress on human mesenchymal stem cells: differential gene expression of IL1B and MAP3K8 in MAPK signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Phenotypic responses to mechanical stress in fibroblasts from tendon, cornea and skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Effect on endothelial cell gene expression of shear stress, oxygen concentration, and low-density lipoprotein as studied by a novel flow cell culture system

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Molecular and mechanical bases of focal lipid accumulation in arterial wall

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Improved significance test for DNA microarray data: temporal effects of shear stress on endothelial genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Prolonged fluid shear stress induces a distinct set of endothelial cell genes, most specifically lung Krüppel-like factor (KLF2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Oxidation-sensitive transcription factors and molecular mechanisms in the arterial wall.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Endothelial Gene Expression in Regions of Defined Shear Exposure in the Porcine Iliac Arteries

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Frequency-dependent response of the vascular endothelium to pulsatile shear stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

A regulatory role of Kruppel-like factor 4 in endothelial argininosuccinate synthetase 1 expression in response to laminar shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

MicroRNA-663 upregulated by oscillatory shear stress plays a role in inflammatory response of endothelial cells

21 January 2018

1 reference

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Integration of flow-dependent endothelial phenotypes by Kruppel-like factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Endothelial cell responses to atheroprone flow are driven by two separate flow components: low time-average shear stress and fluid flow reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Defining the regulation of KLF4 expression and its downstream transcriptional targets in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Characterization of the differential response of endothelial cells exposed to normal and elevated laminar shear stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Endothelial cells express a unique transcriptional profile under very high wall shear stress known to induce expansive arterial remodeling

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Atherosclerosis-prone hemodynamics differentially regulates endothelial and smooth muscle cell phenotypes and promotes pro-inflammatory priming

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Discovery of novel mechanosensitive genes in vivo using mouse carotid artery endothelium exposed to disturbed flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Coexisting proinflammatory and antioxidative endothelial transcription profiles in a disturbed flow region of the adult porcine aorta.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Discovery approaches to UPR in athero-susceptible endothelium in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Chronic endoplasmic reticulum stress activates unfolded protein response in arterial endothelium in regions of susceptibility to atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Coronary artery endothelial transcriptome in vivo: identification of endoplasmic reticulum stress and enhanced reactive oxygen species by gene connectivity network analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

In vivo differences between endothelial transcriptional profiles of coronary and iliac arteries revealed by microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Semi-supervised Nonnegative Matrix Factorization for gene expression deconvolution: a case study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Gene expression deconvolution in clinical samples

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Gene expression of endothelial cells under pulsatile non-reversing vs. steady shear stress; comparison of nitric oxide production.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Differential gene expression in young and senescent endothelial cells under static and laminar shear stress conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

MEK5 is activated by shear stress, activates ERK5 and induces KLF4 to modulate TNF responses in human dermal microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

ERK5 and the regulation of endothelial cell function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Relation Between Endothelial Cell Apoptosis and Blood Flow Direction in Human Atherosclerotic Plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

Stabilisation of atherosclerotic plaques

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FCVR%2FCVT108

21 January 2018

Identifiers

DOI

10.1093/CVR/CVT108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json

release_tj4aimttengqvndmspu6unopy4

29 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tj4aimttengqvndmspu6unopy4

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23650287%20AND%20SRC:MED&resulttype=core&format=json