(Q38106734)

29 August 2017

title

Anticancer carbonic anhydrase inhibitors: a patent review (2008 - 2013). (English)

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29 August 2017

3

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29 August 2017

Simona Maria Monti

1

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Claudiu T Supuran

series ordinal

2

object named as

Claudiu T Supuran

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29 August 2017

language of work or name

English

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publication date

15 May 2013

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Expert Opinion on Therapeutic Patents

29 August 2017

published in

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29 August 2017

volume

23

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29 August 2017

issue

6

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29 August 2017

page(s)

737-749

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Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?

29 August 2017

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Identification of an alternatively spliced isoform of carbonic anhydrase XII in diffusely infiltrating astrocytic gliomas

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Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast

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Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer.

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Selective hydrophobic pocket binding observed within the carbonic anhydrase II active site accommodate different 4-substituted-ureido-benzenesulfonamides and correlate to inhibitor potency

21 January 2018

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Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.

21 January 2018

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Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors

21 January 2018

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Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins

21 January 2018

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7,8-disubstituted- but not 6,7-disubstituted coumarins selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II in the low nanomolar/subnanomolar range

21 January 2018

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Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors.

21 January 2018

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Direct screening of natural product extracts using mass spectrometry.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F13543776.2013.798648

Coumarins incorporating hydroxy- and chloro-moieties selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic ones I and II.

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2013.798648

The protein tyrosine kinase inhibitors imatinib and nilotinib strongly inhibit several mammalian alpha-carbonic anhydrase isoforms.

21 January 2018

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Diuretics: from classical carbonic anhydrase inhibitors to novel applications of the sulfonamides

21 January 2018

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Generation and characterization of the first inhibitory antibody targeting tumour-associated carbonic anhydrase XII.

21 January 2018

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21 January 2018

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Carbonic anhydrase inhibitors — Part 53. Synthesis of substituted-pyridinium derivatives of aromatic sulfonamides: The first non-polymeric membrane-impermeable inhibitors with selectivity for isozyme IV

21 January 2018

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https://api.crossref.org/works/10.1517%2F13543776.2013.798648

10.1517/13543776.2013.798648

21 January 2018

Identifiers

DOI

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29 August 2017

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