(Q38107047)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

16 July 2020

Chitosan for gene delivery and orthopedic tissue engineering applications (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2 references

16 July 2020

1 reference

16 July 2020

1

1 reference

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1 March 2020

Fergal O'Brien

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Sally-Ann Cryan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

language of work or name

English

0 references

publication date

15 May 2013

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

16 July 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

16 July 2020

18

1 reference

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1 March 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

5611-5647

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Creative Commons Attribution

1 March 2020

copyright license

1 reference

16 July 2020

0 references

Microfabricated microneedles for gene and drug delivery

1 reference

12 December 2020

Biomimetic hydrogels for controlled biomolecule delivery to augment bone regeneration.

1 reference

12 December 2020

RNA interference therapy via functionalized scaffolds

1 reference

12 December 2020

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor

1 reference

12 December 2020

Mechanism of cell transfection with plasmid/chitosan complexes

1 reference

12 December 2020

Recent advances on chitosan-based micro- and nanoparticles in drug delivery

1 reference

12 December 2020

Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs

1 reference

12 December 2020

In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis

1 reference

12 December 2020

The performance of nanocarriers for transmucosal drug delivery.

1 reference

12 December 2020

Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery

1 reference

12 December 2020

Bioreactor systems for bone tissue engineering

1 reference

12 December 2020

Structure and pharmacology of the proton-ATPases

1 reference

12 December 2020

Novel method for the preparation of controlled-release theophylline granules coated with a polyelectrolyte complex of sodium polyphosphate-chitosan

1 reference

12 December 2020

Evaluation of polyplexes as gene transfer agents.

1 reference

12 December 2020

Improving chitosan-mediated gene transfer by the introduction of intracellular buffering moieties into the chitosan backbone.

1 reference

12 December 2020

RNAi-induced gene silencing by local electroporation in targeting brain region.

1 reference

12 December 2020

Chitosan chemistry and pharmaceutical perspectives.

1 reference

12 December 2020

Scaffolds based bone tissue engineering: the role of chitosan

1 reference

12 December 2020

Intracellular trafficking and decondensation kinetics of chitosan-pDNA polyplexes

1 reference

12 December 2020

Injectable tissue-engineered bone repair of a rat calvarial defect

1 reference

12 December 2020

Poly(ethylenimine) and its role in gene delivery

1 reference

12 December 2020

Viral and Non-viral Vectors in Gene Therapy: Technology Development and Clinical Trials

1 reference

12 December 2020

Chitosan-based vector/DNA complexes for gene delivery: biophysical characteristics and transfection ability

1 reference

12 December 2020

Bone regeneration by modified gene-activated matrix: effectiveness in segmental tibial defects in rats.

1 reference

12 December 2020

Synthetic biodegradable polymers as orthopedic devices

1 reference

12 December 2020

RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system.

1 reference

12 December 2020

Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan-DNA nanoparticles

1 reference

12 December 2020

In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs.

1 reference

12 December 2020

Environmental enhancement of in vitro chondrogenesis. IV. Stimulation of somite chondrogenesis by exogenous chondromucoprotein.

1 reference

12 December 2020

Viral vectors for gene transfer: a review of their use in the treatment of human diseases

1 reference

12 December 2020

Injectable gels for tissue engineering

1 reference

12 December 2020

Natural-origin polymers as carriers and scaffolds for biomolecules and cell delivery in tissue engineering applications

1 reference

12 December 2020

Silk constructs for delivery of musculoskeletal therapeutics.

1 reference

12 December 2020

Mesenchymal stem cells from development to postnatal joint homeostasis, aging, and disease

1 reference

12 December 2020

Illuminating the silence: understanding the structure and function of small RNAs

1 reference

12 December 2020

Gene therapy for human genetic disease?

1 reference

12 December 2020

Rehabilitation following microfracture for chondral injury in the knee

1 reference

12 December 2020

Preparation and characterization of chitosan microparticles intended for controlled drug delivery

1 reference

12 December 2020

The influence of polymeric properties on chitosan/siRNA nanoparticle formulation and gene silencing.

1 reference

12 December 2020

Engineering RNA for targeted siRNA delivery and medical application

1 reference

12 December 2020

Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo.

1 reference

12 December 2020

Effect of degree of quaternization of N-trimethyl chitosan chloride for enhanced transport of hydrophilic compounds across intestinal caco-2 cell monolayers.

1 reference

12 December 2020

Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends

1 reference

12 December 2020

Non-viral gene delivery systems

1 reference

12 December 2020

Chitosan-based hydrogels for controlled, localized drug delivery

1 reference

12 December 2020

Electroporation-mediated delivery of 3'-protected phosphodiester oligodeoxynucleotides to the skin

1 reference

12 December 2020

Chitosan-mediated stimulation of macrophage function

1 reference

12 December 2020

Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

1 reference

12 December 2020

Comparison of nonviral transfection and adeno-associated viral transduction on cardiomyocytes

1 reference

12 December 2020

Treatment of deep cartilage defects in the knee with autologous chondrocyte transplantation

1 reference

12 December 2020

Development and characterisation of a collagen nano-hydroxyapatite composite scaffold for bone tissue engineering

1 reference

12 December 2020

Enhancement of nasal absorption of insulin using chitosan nanoparticles

1 reference

12 December 2020

Transfection efficiencies of PAMAM dendrimers correlate inversely with their hydrophobicity.

1 reference

12 December 2020

Gene therapy clinical trials worldwide to 2007--an update.

1 reference

12 December 2020

Novel textile chitosan scaffolds promote spreading, proliferation, and differentiation of osteoblasts

1 reference

12 December 2020

Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice

1 reference

12 December 2020

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

1 reference

12 December 2020

Biological activity of chitosan: ultrastructural study

1 reference

12 December 2020

Lactosylated chitosan for DNA delivery into hepatocytes: the effect of lactosylation on the physicochemical properties and intracellular trafficking of pDNA/chitosan complexes

1 reference

12 December 2020

N,N-dicarboxymethyl chitosan as delivery agent for bone morphogenetic protein in the repair of articular cartilage

1 reference

12 December 2020

Gene transfer into eukaryotic cells using activated polyamidoamine dendrimers

1 reference

12 December 2020

An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes

1 reference

12 December 2020

Molecular design of chitosan gene delivery systems with an optimized balance between polyplex stability and polyplex unpacking

1 reference

12 December 2020

Progress and prospects: gene therapy clinical trials (part 1).

1 reference

12 December 2020

Trimethyl chitosan and its applications in drug delivery

1 reference

12 December 2020

Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines

1 reference

12 December 2020

Hypoxia-mimicking mesoporous bioactive glass scaffolds with controllable cobalt ion release for bone tissue engineering

1 reference

12 December 2020

The art of microRNA research

1 reference

12 December 2020

Less harmful acidic degradation of poly(lacticco-glycolic acid) bone tissue engineering scaffolds through titania nanoparticle addition.

1 reference

12 December 2020

Receptor-mediated gene delivery and expression in vivo.

1 reference

12 December 2020

Delivering the goods: viral and non-viral gene therapy systems and the inherent limits on cargo DNA and internal sequences

1 reference

12 December 2020

The development of non-viral gene-activated matrices for bone regeneration using polyethyleneimine (PEI) and collagen-based scaffolds

1 reference

12 December 2020

Chitosan enhances mineralization during osteoblast differentiation of human bone marrow-derived mesenchymal stem cells, by upregulating the associated genes.

1 reference

12 December 2020

Structure/property studies of polymeric gene delivery using a library of poly(beta-amino esters).

1 reference

12 December 2020

A critical review of recombinant human bone morphogenetic protein-2 trials in spinal surgery: emerging safety concerns and lessons learned

1 reference

12 December 2020

Addition of hydroxyapatite improves stiffness, interconnectivity and osteogenic potential of a highly porous collagen-based scaffold for bone tissue regeneration.

1 reference

12 December 2020

Direct gene therapy for bone regeneration: gene delivery, animal models, and outcome measures.

1 reference

12 December 2020

Vascular endothelial growth factor gene-activated matrix (VEGF165-GAM) enhances osteogenesis and angiogenesis in large segmental bone defects.

1 reference

12 December 2020

Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery.

1 reference

12 December 2020

Long-term delivery enhances in vivo osteogenic efficacy of bone morphogenetic protein-2 compared to short-term delivery.

1 reference

12 December 2020

High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation

1 reference

12 December 2020

Stimulatory effect on bone formation exerted by a modified chitosan

1 reference

12 December 2020

An update on bone substitutes for spinal fusion

1 reference

12 December 2020

Antibacterial activity of chitosans and chitosan oligomers with different molecular weights

1 reference

12 December 2020

Polyethylenimine-mediated gene delivery: a mechanistic study

1 reference

12 December 2020

MicroRNAs: genomics, biogenesis, mechanism, and function

1 reference

12 December 2020

Biophysical properties of chitosan/siRNA polyplexes: profiling the polymer/siRNA interactions and bioactivity

1 reference

12 December 2020

Preparation and characterization of macroporous chitosan–gelatin/β‐tricalcium phosphate composite scaffolds for bone tissue engineering

1 reference

12 December 2020

Osteoconductive properties of methylpyrrolidinone chitosan in an animal model.

1 reference

12 December 2020

Prospects of stem cell therapy in osteoarthritis

1 reference

12 December 2020

Chitosan-cobalt(II) and nickel(II) chelates as antibacterial agents

1 reference

12 December 2020

Bone-grafting and bone-graft substitutes.

1 reference

12 December 2020

Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA.

1 reference

12 December 2020

Chitosan and its use as a pharmaceutical excipient

1 reference

12 December 2020

Low molecular weight oligochitosans for non-viral retinal gene therapy

1 reference

12 December 2020

Biominerals--hierarchical nanocomposites: the example of bone

1 reference

12 December 2020

Receptor-mediated peptide delivery in pulmonary epithelial monolayers

1 reference

12 December 2020

Chitosan/siRNA nanoparticle-mediated TNF-alpha knockdown in peritoneal macrophages for anti-inflammatory treatment in a murine arthritis model

1 reference

12 December 2020

Silencing of microRNAs in vivo with 'antagomirs'

1 reference

12 December 2020

Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli

1 reference

12 December 2020

Bone regeneration in a rat cranial defect with delivery of PEI-condensed plasmid DNA encoding for bone morphogenetic protein-4 (BMP-4).

1 reference

12 December 2020

Transmission of disease through transplantation of musculoskeletal allografts

1 reference

12 December 2020

Localized, direct plasmid gene delivery in vivo: prolonged therapy results in reproducible tissue regeneration

1 reference

12 December 2020

Designing Bioactive Delivery Systems for Tissue Regeneration

1 reference

12 December 2020

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

1 reference

12 December 2020

Electrospinning of chitosan dissolved in concentrated acetic acid solution

1 reference

12 December 2020

Electrospun fibrous scaffolds for bone and cartilage tissue generation: recent progress and future developments

1 reference

12 December 2020

Current status of polymeric gene delivery systems

1 reference

12 December 2020

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

1 reference

12 December 2020

Combination of local and systemic parathyroid hormone enhances bone regeneration

1 reference

12 December 2020

The ability of a collagen/calcium phosphate scaffold to act as its own vector for gene delivery and to promote bone formation via transfection with VEGF(165).

1 reference

12 December 2020

Oral gene delivery with chitosan--DNA nanoparticles generates immunologic protection in a murine model of peanut allergy.

1 reference

12 December 2020

Composite chitosan/nano-hydroxyapatite scaffolds induce osteocalcin production by osteoblasts in vitro and support bone formation in vivo.

1 reference

12 December 2020

Chitosan and depolymerized chitosan oligomers as condensing carriers for in vivo plasmid delivery

1 reference

12 December 2020

Sustained correction of X-linked severe combined immunodeficiency by ex vivo gene therapy

1 reference

12 December 2020

Novel gene-activated matrix with embedded chitosan/plasmid DNA nanoparticles encoding PDGF for periodontal tissue engineering

1 reference

12 December 2020

Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles

1 reference

12 December 2020

Gene expression profiles in mouse lung tissue after administration of two cationic polymers used for nonviral gene delivery

1 reference

12 December 2020

High levels of ephrinB2 over-expression increases the osteogenic differentiation of human mesenchymal stem cells and promotes enhanced cell mediated mineralisation in a polyethyleneimine-ephrinB2 gene-activated matrix

1 reference

12 December 2020

Development and characterisation of chitosan nanoparticles for siRNA delivery

1 reference

12 December 2020

Gene delivery in bone tissue engineering: progress and prospects using viral and nonviral strategies.

1 reference

12 December 2020

Direct gene transfer into skeletal muscle in vivo: factors affecting efficiency of transfer and stability of expression

1 reference

12 December 2020

Nonviral vectors for gene delivery

1 reference

12 December 2020

Biodegradation, biodistribution and toxicity of chitosan

1 reference

12 December 2020

Influence of chitosan structure on the formation and stability of DNA-chitosan polyelectrolyte complexes

1 reference

12 December 2020

Design and development of polymers for gene delivery

1 reference

12 December 2020

State-of-the-art gene-based therapies: the road ahead

1 reference

12 December 2020

Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review

1 reference

12 December 2020

Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: Scaffold design and its performance when seeded with goat bone marrow stromal cells.

1 reference

12 December 2020

Effects of chitosan on rat knee cartilages

1 reference

12 December 2020

Biodisposition characteristics of N-succinyl-chitosan and glycol-chitosan in normal and tumor-bearing mice.

1 reference

12 December 2020

Enhanced bone formation by controlled growth factor delivery from chitosan-based biomaterials.

1 reference

12 December 2020

Progress and prospects: gene therapy clinical trials (part 2).

1 reference

12 December 2020

Multilineage potential of adult human mesenchymal stem cells

1 reference

12 December 2020

Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

1 reference

12 December 2020

Galactosylated chitosan-graft-dextran as hepatocyte-targeting DNA carrier

1 reference

12 December 2020

Chitosan--as a biomaterial

1 reference

12 December 2020

Drug delivery in soft tissue engineering

1 reference

12 December 2020

Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery.

1 reference

12 December 2020

Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery.

1 reference

12 December 2020

Nonviral gene delivery: techniques and implications for molecular medicine.

1 reference

12 December 2020

Bone substitutes: an update

1 reference

12 December 2020

The influence of formulation variables on in vitro transfection efficiency and physicochemical properties of chitosan-based polyplexes

1 reference

12 December 2020

Polymeric system for dual growth factor delivery

1 reference

12 December 2020

Controlled release of albumin from chitosan-alginate microcapsules

1 reference

12 December 2020

Therapeutic potential of chitosan and its derivatives in regenerative medicine

1 reference

12 December 2020

Chitin and chitosan induce migration of bovine polymorphonuclear cells

1 reference

12 December 2020

Chitosan-based formulations for delivery of DNA and siRNA.

1 reference

12 December 2020

Lysozyme degradation of partially deacetylated chitin, its films and hydrogels

1 reference

12 December 2020

Studies on chitosan: 2. Solution stability and reactivity of partially N-acetylated chitosan derivatives in aqueous media

1 reference

12 December 2020

Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo

1 reference

12 December 2020

Tissue engineering by modulated gene delivery.

1 reference

12 December 2020

Mechanisms of synovial joint and articular cartilage formation: recent advances, but many lingering mysteries

1 reference

12 December 2020

Receptor-mediated in vitro gene transformation by a soluble DNA carrier system

1 reference

12 December 2020

Cationic polymer based gene delivery systems

1 reference

12 December 2020

DNA-polycation nanospheres as non-viral gene delivery vehicles

1 reference

12 December 2020

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics

1 reference

12 December 2020

Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation.

1 reference

12 December 2020

Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation

1 reference

12 December 2020

Transfection of primary chondrocytes using chitosan-pEGFP nanoparticles

1 reference

12 December 2020

Gene therapy for bone healing

1 reference

12 December 2020

Development of a thermoresponsive chitosan gel combined with human mesenchymal stem cells and desferrioxamine as a multimodal pro-angiogenic therapeutic for the treatment of critical limb ischaemia

1 reference

12 December 2020

Effects of the controlled-released TGF-beta 1 from chitosan microspheres on chondrocytes cultured in a collagen/chitosan/glycosaminoglycan scaffold

1 reference

12 December 2020

Glycosaminoglycans and Their Binding to Biological Macromolecules

1 reference

12 December 2020

In vitro gene delivery mediated by chitosan. effect of pH, serum, and molecular mass of chitosan on the transfection efficiency

1 reference

12 December 2020

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

1 reference

12 December 2020

Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides.

1 reference

12 December 2020

Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

1 reference

12 December 2020

Innovative collagen nano-hydroxyapatite scaffolds offer a highly efficient non-viral gene delivery platform for stem cell-mediated bone formation

1 reference

12 December 2020

DNA-based therapeutics and DNA delivery systems: a comprehensive review

1 reference

12 December 2020

Osteoconduction exerted by methylpyrrolidinone chitosan used in dental surgery

1 reference

12 December 2020

Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis

1 reference

12 December 2020

Local controlled release of VEGF and PDGF from a combined brushite-chitosan system enhances bone regeneration

1 reference

12 December 2020

Early management of osteoarthritis.

1 reference

12 December 2020

Tissue engineered bone grafts: biological requirements, tissue culture and clinical relevance

1 reference

12 December 2020

Porous chitosan scaffolds for tissue engineering

1 reference

12 December 2020

Efficient gene transfection by histidine-modified chitosan through enhancement of endosomal escape

1 reference

12 December 2020

Viral vectors for gene delivery in tissue engineering

1 reference

12 December 2020

10.3390/MOLECULES18055611

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

PubMed publication ID

23676471

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23676471%20AND%20SRC:MED&resulttype=core&format=json