(Q38108631)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

title

Incretin hormones and beta-cell mass expansion: what we know and what is missing? (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

author name string

Federica Tortosa

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

publication date

23 May 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

Archives of Physiology and Biochemistry

1 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

volume

119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

page(s)

161-169

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23697580%20AND%20SRC:MED&resulttype=core&format=json

The pharmacokinetics, pharmacodynamics, safety and tolerability of NN2211, a new long-acting GLP-1 derivative, in healthy men.

1 March 2020

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Incretin-based therapies in type 2 diabetes mellitus

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Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

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Mechanisms of pancreatic beta-cell death in type 1 and type 2 diabetes: many differences, few similarities

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Molecular control of cell cycle progression in the pancreatic beta-cell

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Glucagon-like peptide-1 agonists protect pancreatic beta-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB.

21 January 2018

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Pancreatic beta-cells expressing GLP-1 are resistant to the toxic effects of immunosuppressive drugs

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Physiology of incretins in health and disease

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Functional and molecular defects of pancreatic islets in human type 2 diabetes

21 January 2018

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Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications

21 January 2018

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Mechanisms of beta-cell death in type 2 diabetes.

21 January 2018

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Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

21 January 2018

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Facultative endocrine progenitor cells in the adult pancreas

21 January 2018

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Glucagon-like peptide I stimulates insulin gene expression and increases cyclic AMP levels in a rat islet cell line

21 January 2018

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Biological actions and therapeutic potential of the glucagon-like peptides

21 January 2018

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Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

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Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway.

21 January 2018

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Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase.

21 January 2018

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Glucagon-like peptide-1 (7-36)amide and glucose-dependent insulinotropic polypeptide secretion in response to nutrient ingestion in man: acute post-prandial and 24-h secretion patterns.

21 January 2018

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Glucagon-like peptide-1 promotes islet cell growth and inhibits apoptosis in Zucker diabetic rats.

21 January 2018

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Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways.

21 January 2018

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The emerging role of autophagy in the pathophysiology of diabetes mellitus

21 January 2018

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Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4alpha

21 January 2018

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Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine

21 January 2018

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Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function

21 January 2018

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Intrinsic regulators of pancreatic beta-cell proliferation

21 January 2018

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Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1-positive pancreatic ductal cells into insulin-secreting cells

21 January 2018

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Pancreas duodenum homeobox-1 regulates pancreas development during embryogenesis and islet cell function in adulthood

21 January 2018

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Glucagon-like peptide-1 inhibits apoptosis of insulin-secreting cells via a cyclic 5'-adenosine monophosphate-dependent protein kinase A- and a phosphatidylinositol 3-kinase-dependent pathway

21 January 2018

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A novel method for the assessment of cellular composition and beta-cell viability in human islet preparations

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Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

21 January 2018

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Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1

21 January 2018

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Critical role of cAMP-GEFII--Rim2 complex in incretin-potentiated insulin secretion

21 January 2018

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Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and dow

21 January 2018

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Glucose-dependent insulinotropic polypeptide-mediated up-regulation of beta-cell antiapoptotic Bcl-2 gene expression is coordinated by cyclic AMP (cAMP) response element binding protein (CREB) and cAMP-responsive CREB coactivator 2

21 January 2018

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Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration

21 January 2018

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PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance

21 January 2018

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cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells

21 January 2018

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Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.

21 January 2018

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Regulation of beta cell replication.

21 January 2018

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Autophagy in the Pathogenesis of Disease

21 January 2018

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Combination of GLP-1 and sodium butyrate promote differentiation of pancreatic progenitor cells into insulin-producing cells

21 January 2018

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Structure-activity and protraction relationship of long-acting glucagon-like peptide-1 derivatives: importance of fatty acid length, polarity, and bulkiness

21 January 2018

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Differential importance of glucose-dependent insulinotropic polypeptide vs glucagon-like peptide 1 receptor signaling for beta cell survival in mice

21 January 2018

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Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin.

21 January 2018

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An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment.

21 January 2018

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A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets.

21 January 2018

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Sustained beta cell apoptosis in patients with long-standing type 1 diabetes: indirect evidence for islet regeneration?

21 January 2018

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Beta-cell replication is the primary mechanism subserving the postnatal expansion of beta-cell mass in humans

21 January 2018

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Overexpression of glucagon-like peptide-1 receptor in an insulin-secreting cell line enhances glucose responsiveness

21 January 2018

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Adult mouse intrahepatic biliary epithelial cells induced in vitro to become insulin-producing cells

21 January 2018

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Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells

21 January 2018

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Preserved incretin activity of glucagon-like peptide 1 [7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

21 January 2018

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Incretin-based therapies for type 2 diabetes mellitus: properties, functions, and clinical implications

21 January 2018

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Recovery from diabetes in mice by beta cell regeneration

21 January 2018

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Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance

21 January 2018

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HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

21 January 2018

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Number and size of islets of Langerhans in pregnant, human growth hormone-expressing transgenic, and pituitary dwarf mice: effect of lactogenic hormones

21 January 2018

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Lipotoxicity impairs incretin signalling.

21 January 2018

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Islet beta cell failure in type 2 diabetes

21 January 2018

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

21 January 2018

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Type 2 diabetes-a matter of beta-cell life and death?

21 January 2018

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Expansion of beta-cell mass in response to pregnancy

21 January 2018

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Colocalization of the alpha-subunit of gustducin with PYY and GLP-1 in L cells of human colon

21 January 2018

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Expansion of mesenchymal stem cells from human pancreatic ductal epithelium

21 January 2018

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Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs

21 January 2018

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Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

21 January 2018

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Neonatal exendin-4 prevents the development of diabetes in the intrauterine growth retarded rat.

21 January 2018

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The defined combination of growth factors controls generation of long-term-replicating islet progenitor-like cells from cultures of adult mouse pancreas.

21 January 2018

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Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice.

21 January 2018

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Very slow turnover of beta-cells in aged adult mice

21 January 2018

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Growth and regeneration of adult beta cells does not involve specialized progenitors.

21 January 2018

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Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

21 January 2018

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Generation of human islets through expansion and differentiation of non-islet pancreatic cells discarded (pancreatic discard) after islet isolation

21 January 2018

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Glucagon-like peptide-1 and exendin-4 stimulate beta-cell neogenesis in streptozotocin-treated newborn rats resulting in persistently improved glucose homeostasis at adult age.

21 January 2018

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Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells

21 January 2018

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The Rap-B-Raf signalling pathway is activated by glucose and glucagon-like peptide-1 in human islet cells

21 January 2018

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Age-dependent decline in beta-cell proliferation restricts the capacity of beta-cell regeneration in mice

21 January 2018

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Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice

21 January 2018

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Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells

21 January 2018

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The influence of amyloid deposits on the islet volume in maturity onset diabetes mellitus

21 January 2018

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Aggregate-prone proteins are cleared from the cytosol by autophagy: therapeutic implications

21 January 2018

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Exendin-4 stimulates both beta-cell replication and neogenesis, resulting in increased beta-cell mass and improved glucose tolerance in diabetic rats

21 January 2018

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Beta cells can be generated from endogenous progenitors in injured adult mouse pancreas

21 January 2018

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Overexpression of cyclin D1 in pancreatic beta-cells in vivo results in islet hyperplasia without hypoglycemia.

21 January 2018

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Exendin-4 differentiation of a human pancreatic duct cell line into endocrine cells: involvement of PDX-1 and HNF3beta transcription factors

21 January 2018

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In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

21 January 2018

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Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes

21 January 2018

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Autophagy and the pancreatic beta-cell in human type 2 diabetes

21 January 2018

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https://api.crossref.org/works/10.3109%2F13813455.2013.795175

Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in Korea

21 January 2018

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Both Subcutaneously and Intravenously Administered Glucagon-Like Peptide I Are Rapidly Degraded From the NH2-Terminus in Type II Diabetic Patients and in Healthy Subjects

21 January 2018

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GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

21 January 2018

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Secretion of the Incretin Hormones Glucagon-Like Peptide-1 and Gastric Inhibitory Polypeptide Correlates with Insulin Secretion in Normal Man Throughout the Day

21 January 2018

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Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans

21 January 2018

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