(Q38115636)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

0 references

1 reference

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

author name string

Vanesa Stepanov

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

Karmen Stankov

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

publication date

20 June 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

Journal of Receptors and Signal Transduction

3 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

issue

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

page(s)

213-223

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

Fifty years of advances in bile acid synthesis and metabolism

3 March 2020

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The bile acid membrane receptor TGR5: a valuable metabolic target

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The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain

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Incretin-based therapies for type 2 diabetes mellitus

21 January 2018

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Addition of incretin therapy to metformin in type 2 diabetes

21 January 2018

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The biology of incretin hormones

21 January 2018

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Bile acids promote glucagon-like peptide-1 secretion through TGR5 in a murine enteroendocrine cell line STC-1.

21 January 2018

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TGR5-mediated bile acid sensing controls glucose homeostasis

21 January 2018

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Bile acids and the membrane bile acid receptor TGR5--connecting nutrition and metabolism

21 January 2018

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TGR5 potentiates GLP-1 secretion in response to anionic exchange resins

21 January 2018

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GLP-1 inhibits and adrenaline stimulates glucagon release by differential modulation of N- and L-type Ca2+ channel-dependent exocytosis

21 January 2018

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Bile-induced secretion of glucagon-like peptide-1: pathophysiological implications in type 2 diabetes?

21 January 2018

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Current and future drug targets in weight management

21 January 2018

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Incretin-based therapies: mimetics versus protease inhibitors

21 January 2018

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Targeting the TGR5-GLP-1 pathway to combat type 2 diabetes and non-alcoholic fatty liver disease

21 January 2018

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The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation

21 January 2018

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Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

21 January 2018

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Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

21 January 2018

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Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.

21 January 2018

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Gender-dependent effect of Gpbar1 genetic deletion on the metabolic profiles of diet-induced obese mice

21 January 2018

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Plasma bile acids are not associated with energy metabolism in humans

21 January 2018

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The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation

21 January 2018

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Macrophages, inflammation, and insulin resistance

21 January 2018

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NF-kappaB functions as a tumour promoter in inflammation-associated cancer

21 January 2018

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SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity

21 January 2018

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Expression and function of the bile acid receptor TGR5 in Kupffer cells

21 January 2018

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Bile acid receptors as targets for the treatment of dyslipidemia and cardiovascular disease

21 January 2018

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21 January 2018

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21 January 2018

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TGR5 activation inhibits atherosclerosis by reducing macrophage inflammation and lipid loading

21 January 2018

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NF-κB, inflammation, and metabolic disease.

21 January 2018

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21 January 2018

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The G-protein-coupled bile acid receptor, Gpbar1 (TGR5), negatively regulates hepatic inflammatory response through antagonizing nuclear factor κ light-chain enhancer of activated B cells (NF-κB) in mice

21 January 2018

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Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation

21 January 2018

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The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis

21 January 2018

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Biliary decompression promotes Kupffer cell recovery in obstructive jaundice

21 January 2018

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21 January 2018

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Reversible Kupffer cell suppression in biliary obstruction is caused by hydrophobic bile acids.

21 January 2018

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The role of bile acids in the development of endotoxemia during obstructive jaundice in the rat.

21 January 2018

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NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

1 reference

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The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Pathogenesis of the hyperlipidemia of Gram-negative bacterial sepsis may involve pathomorphological changes in liver sinusoidal endothelial cells

21 January 2018

1 reference

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Scavenger receptors on sinusoidal liver endothelial cells are involved in the uptake of aldehyde-modified proteins

21 January 2018

1 reference

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Expression and localization of hepatobiliary transport proteins in progressive familial intrahepatic cholestasis

21 January 2018

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Inhibition of bile salt-induced apoptosis by cyclic AMP involves serine/threonine phosphorylation of CD95.

21 January 2018

1 reference

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CD95 death receptor and epidermal growth factor receptor (EGFR) in liver cell apoptosis and regeneration

21 January 2018

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The role of nitric oxide synthase isoforms in extrahepatic portal hypertension: studies in gene-knockout mice.

21 January 2018

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The molecules: mechanisms of arterial vasodilatation observed in the splanchnic and systemic circulation in portal hypertension

21 January 2018

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Role of endothelial nitric oxide synthase in the development of portal hypertension in the carbon tetrachloride-induced liver fibrosis model.

21 January 2018

1 reference

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Identification of circulatory and excretory metabolites of a novel nitric oxide donor ZJM-289 in rat plasma, bile, urine and faeces by liquid chromatography-tandem mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

The membrane-bound bile acid receptor TGR5 is localized in the epithelium of human gallbladders

21 January 2018

1 reference

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21 January 2018

TGR5 in the biliary tree

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling

21 January 2018

1 reference

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Hydrophobic bile salts inhibit gallbladder smooth muscle function via stimulation of GPBAR1 receptors and activation of KATP channels.

21 January 2018

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21 January 2018

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21 January 2018

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Growth signals, inflammation, and vascular perturbations: mechanistic links between obesity, metabolic syndrome, and cancer

21 January 2018

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Diabetes, body mass index, and outcomes in hepatocellular carcinoma patients undergoing liver transplantation.

21 January 2018

1 reference

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Bile acid-induced TGR5-dependent c-Jun-N terminal kinase activation leads to enhanced caspase 8 activation in hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Deficiency of G-protein-coupled bile acid receptor Gpbar1 (TGR5) enhances chemically induced liver carcinogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Regulation of the IL-23 and IL-12 balance by Stat3 signaling in the tumor microenvironment

21 January 2018

1 reference

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Crosstalk of Sp1 and Stat3 signaling in pancreatic cancer pathogenesis

21 January 2018

1 reference

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Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line

21 January 2018

1 reference

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Involvement of membrane-type bile acid receptor M-BAR/TGR5 in bile acid-induced activation of epidermal growth factor receptor and mitogen-activated protein kinases in gastric carcinoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

The role of bile acids in the neoplastic progression of Barrett's esophagus - a short representative overview

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Role of a novel bile acid receptor TGR5 in the development of oesophageal adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Chenodeoxycholic acid through a TGR5-dependent CREB signaling activation enhances cyclin D1 expression and promotes human endometrial cancer cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Structure-activity relationship study of betulinic acid, a novel and selective TGR5 agonist, and its synthetic derivatives: potential impact in diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Discovery of 6alpha-ethyl-23(S)-methylcholic acid (S-EMCA, INT-777) as a potent and selective agonist for the TGR5 receptor, a novel target for diabesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Discovery of 3-aryl-4-isoxazolecarboxamides as TGR5 receptor agonists

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Biliary acute pancreatitis in mice is mediated by the G-protein-coupled cell surface bile acid receptor Gpbar1.

21 January 2018

1 reference

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Non-systemic drugs: a critical review

21 January 2018

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Role of bile acid sequestrants in the treatment of type 2 diabetes

21 January 2018

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A review of the efficacy and safety of oral antidiabetic drugs

21 January 2018

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Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F10799893.2013.802805

Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice.

21 January 2018

1 reference

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10.3109/10799893.2013.802805

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23782454%20AND%20SRC:MED&resulttype=core&format=json

release_3foajumhirgwbh32tangc52jee

3 March 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/3foajumhirgwbh32tangc52jee

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference