(Q38117426)

29 August 2017

Effects of interleukin-1 on cardiac fibroblast function: relevance to post-myocardial infarction remodelling (English)

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29 August 2017

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myocardial infarction

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Neil A Turner

1

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publication date

24 June 2013

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PubMed ID

23806284

full work available at URL

29 August 2017

http://eprints.whiterose.ac.uk/77826/

content deliverer

White Rose Research Online

object has role

postprint

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published in

Vascular Pharmacology

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29 August 2017

60

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29 August 2017

1

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29 August 2017

1-7

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Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (Virginia Commonwealth University Anakinra Remodeling Trial [VCU-ART] Pilot study).

29 August 2017

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Effects of interleukin-1 blockade with anakinra on adverse cardiac remodeling and heart failure after acute myocardial infarction [from the Virginia Commonwealth University-Anakinra Remodeling Trial (2) (VCU-ART2) pilot study].

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1beta modulation using a genetically engineered antibody prevents adverse cardiac remodelling following acute myocardial infarction in the mouse

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function

7 January 2021

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IL-1, IL-18, and IL-33 families of cytokines

7 January 2021

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Innate immune signaling in cardiac ischemia

7 January 2021

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Determination of cell types and numbers during cardiac development in the neonatal and adult rat and mouse

7 January 2021

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Myeloid differentiation factor-88/interleukin-1 signaling controls cardiac fibrosis and heart failure progression in inflammatory dilated cardiomyopathy.

7 January 2021

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Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.

7 January 2021

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The cardiac fibroblast: therapeutic target in myocardial remodeling and failure

7 January 2021

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Cytokines regulate matrix metalloproteinases and migration in cardiac fibroblasts

7 January 2021

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Interleukin-1 receptor type I signaling critically regulates infarct healing and cardiac remodeling.

7 January 2021

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The role of IL-1 in the pathogenesis of heart disease.

7 January 2021

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Differential behaviors of atrial versus ventricular fibroblasts: a potential role for platelet-derived growth factor in atrial-ventricular remodeling differences

7 January 2021

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Structural and functional coupling of cardiac myocytes and fibroblasts.

7 January 2021

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Identification of a key pathway required for the sterile inflammatory response triggered by dying cells

7 January 2021

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Fibroblasts in post-infarction inflammation and cardiac repair.

7 January 2021

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Endogenous IRAK-M attenuates postinfarction remodeling through effects on macrophages and fibroblasts.

7 January 2021

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Investigation of the effect of Interleukin-1 receptor antagonist (IL-1ra) on markers of inflammation in non-ST elevation acute coronary syndromes (The MRC-ILA-HEART Study).

7 January 2021

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MyD88-dependent and -independent signaling by IL-1 in neurons probed by bifunctional Toll/IL-1 receptor domain/BB-loop mimetics

7 January 2021

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Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Cardiac cytokine expression is upregulated in the acute phase after myocardial infarction. Experimental studies in rats

7 January 2021

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Of mice and dogs: species-specific differences in the inflammatory response following myocardial infarction.

7 January 2021

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The many worlds of reducing interleukin-1

7 January 2021

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Interleukin-1 in the pathogenesis and treatment of inflammatory diseases

7 January 2021

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Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

7 January 2021

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NOD1 activation induces cardiac dysfunction and modulates cardiac fibrosis and cardiomyocyte apoptosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The interleukin-1 receptor-associated kinases: critical regulators of innate immune signalling.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The immune system and cardiac repair.

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Multiple facets of NF-κB in the heart: to be or not to NF-κB.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Imidaprilat inhibits matrix metalloproteinase-2 activity in human cardiac fibroblasts induced by interleukin-1beta via NO-dependent pathway.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

7 January 2021

1 reference

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A physiological concentration of glucocorticoid inhibits the pro-inflammatory cytokine-induced proliferation of adult rat cardiac fibroblasts: roles of extracellular signal-regulated kinase 1/2 and nuclear factor-κB.

7 January 2021

1 reference

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Myocardial hypertrophy in transgenic mice overexpressing human interleukin 1alpha

7 January 2021

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Ventricular remodeling after infarction and the extracellular collagen matrix: when is enough enough?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Inflammasome activation of cardiac fibroblasts is essential for myocardial ischemia/reperfusion injury

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Cardiac fibroblasts arrest at the G1/S restriction point in response to interleukin (IL)-1beta. Evidence for IL-1beta-induced hypophosphorylation of the retinoblastoma protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The origin of fibroblasts and mechanism of cardiac fibrosis

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Cardiac fibroblasts influence cardiomyocyte phenotype in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Emerging inflammasome effector mechanisms.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Decreased p38 MAPK activity in end-stage failing human myocardium: p38 MAPK alpha is the predominant isoform expressed in human heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The role of interleukin-1 in the failing heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1 has opposing effects on connective tissue growth factor and tenascin-C expression in human cardiac fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The p38 mitogen-activated protein kinase pathway--a potential target for intervention in infarction, hypertrophy, and heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The inflammasome promotes adverse cardiac remodeling following acute myocardial infarction in the mouse.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

IL-1β stimulates rat cardiac fibroblast migration via MAP kinase pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Peroxisome proliferator-activated receptor gamma-independent effects of thiazolidinediones on human cardiac myofibroblast function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Left ventricular hypertrophy in mice with a cardiac-specific overexpression of interleukin-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Expression of Gi-2α and Gsα in myofibroblasts localized to the infarct scar in heart failure due to myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Endothelin-1 stimulates cardiac fibroblast proliferation through activation of protein kinase C.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Cardiac fibroblasts: at the heart of myocardial remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

p38 MAPK alpha mediates cytokine-induced IL-6 and MMP-3 expression in human cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1beta and tumor necrosis factor-alpha decrease collagen synthesis and increase matrix metalloproteinase activity in cardiac fibroblasts in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Innate immune signaling induces expression and shedding of the heparan sulfate proteoglycan syndecan-4 in cardiac fibroblasts and myocytes, affecting inflammation in the pressure-overloaded heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Regression of cardiac hypertrophy by granulocyte colony-stimulating factor-stimulated interleukin-1β synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Myofibroblasts and mechano-regulation of connective tissue remodelling

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Therapeutic regulation of cardiac fibroblast function: targeting stress-activated protein kinase pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Human cardiac fibroblasts express ICAM-1, E-selectin and CXC chemokines in response to proinflammatory cytokine stimulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1alpha stimulates proinflammatory cytokine expression in human cardiac myofibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Mechanism of TNFalpha-induced IL-1alpha, IL-1beta and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Regulation of myocardial matrix metalloproteinase expression and activity by cardiac fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Function and fate of myofibroblasts after myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Modulatory effect of interleukin-1α on expression of structural matrix proteins, MMPs and TIMPs in human cardiac myofibroblasts: role of p38 MAP kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Myocardial remodeling after infarction: the role of myofibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Combined effects of interleukin-1α and transforming growth factor-β1 on modulation of human cardiac fibroblast function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

The role of cardiac fibroblasts in the transition from inflammation to fibrosis following myocardial infarction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Interleukin-1 trap attenuates cardiac remodeling after experimental acute myocardial infarction in mice

7 January 2021

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The precursor form of IL-1alpha is an intracrine proinflammatory activator of transcription

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Endotoxin-activated cultured neonatal rat cardiomyocytes express functional surface-associated interleukin-1alpha

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Differential regulation of matrix metalloproteinase-2 and -9 expression and activity in adult rat cardiac fibroblasts in response to interleukin-1beta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Origins of cardiac fibroblasts

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Differential vulnerability to oxidative stress in rat cardiac myocytes versus fibroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Release of pro- and anti-angiogenic factors by human cardiac fibroblasts: effects on DNA synthesis and protection under hypoxia in human endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

Cell death, damage-associated molecular patterns, and sterile inflammation in cardiovascular disease

7 January 2021

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https://api.crossref.org/works/10.1016%2FJ.VPH.2013.06.002

10.1016/J.VPH.2013.06.002

7 January 2021

Identifiers

DOI

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29 August 2017

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