(Q50335885)

English

Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components.

scientific article published on 15 May 2007

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scholarly article

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Mass spectrometric analysis of the endogenous type I interleukin-1 (IL-1) receptor signaling complex formed after IL-1 binding identifies IL-1RAcP, MyD88, and IRAK-4 as the stable components. (English)

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Luke A. J. O'Neill

4

object named as

Luke A J O'Neill

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

author name string

Constantinos Brikos

1

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Robin Wait

2

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Shajna Begum

3

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Jeremy Saklatvala

5

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

publication date

15 May 2007

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Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Molecular & Cellular Proteomics

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

6

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

9

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Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

1551-1559

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

Structure-function analysis of human IL-1 alpha: identification of residues required for binding to the human type I IL-1 receptor

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

A mutational analysis of receptor binding sites of interleukin-1 beta: differences in binding of human interleukin-1 beta muteins to human and mouse receptors.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Detection and characterization of high affinity plasma membrane receptors for human interleukin 1.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Mammalian MAP kinase signalling cascades

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Molecular cloning and characterization of a second subunit of the interleukin 1 receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Identification of essential regions in the cytoplasmic tail of interleukin-1 receptor accessory protein critical for interleukin-1 signaling

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

MyD88: an adapter that recruits IRAK to the IL-1 receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

MyD88, an adapter protein involved in interleukin-1 signaling

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IRAK: a kinase associated with the interleukin-1 receptor

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IRAK-M is a novel member of the Pelle/interleukin-1 receptor-associated kinase (IRAK) family

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IRAK-4: a novel member of the IRAK family with the properties of an IRAK-kinase

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

TRAF6 is a signal transducer for interleukin-1

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IRAK-mediated translocation of TRAF6 and TAB2 in the interleukin-1-induced activation of NFkappa B

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Interleukin-1 (IL-1) receptor-associated kinase-dependent IL-1-induced signaling complexes phosphorylate TAK1 and TAB2 at the plasma membrane and activate TAK1 in the cytosol

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

TAB2, a novel adaptor protein, mediates activation of TAK1 MAPKKK by linking TAK1 to TRAF6 in the IL-1 signal transduction pathway

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

TAK1 mitogen-activated protein kinase kinase kinase is activated by autophosphorylation within its activation loop

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Phosphorylation-dependent activation of TAK1 mitogen-activated protein kinase kinase kinase by TAB1

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

TAK1 is critical for IkappaB kinase-mediated activation of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Effects of overexpression of IL-1 receptor-associated kinase on NFkappaB activation, IL-2 production and stress-activated protein kinases in the murine T cell line EL4.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Mutant cells that do not respond to interleukin-1 (IL-1) reveal a novel role for IL-1 receptor-associated kinase

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Overexpression of an enzymically inactive interleukin-1-receptor-associated kinase activates nuclear factor-kappaB

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Pyogenic bacterial infections in humans with IRAK-4 deficiency

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Interleukin-1-induced activation of a protein kinase co-precipitating with the type I interleukin-1 receptor in T cells

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Proteins of rat serum, urine, and cerebrospinal fluid: VI. Further protein identifications and interstrain comparison

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Strategies for proteomics with incompletely characterized genomes: the proteome of Bos taurus serum

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Translocation of the interleukin-1 receptor-associated kinase-1 (IRAK-1) into the nucleus

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Pellino 1 is required for interleukin-1 (IL-1)-mediated signaling through its interaction with the IL-1 receptor-associated kinase 4 (IRAK4)-IRAK-tumor necrosis factor receptor-associated factor 6 (TRAF6) complex

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Inhibition of interleukin 1 receptor/Toll-like receptor signaling through the alternatively spliced, short form of MyD88 is due to its failure to recruit IRAK-4

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Toll-like receptors as molecular switches.

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Phosphatidylinositol 3-kinase is involved in Toll-like receptor 4-mediated cytokine expression in mouse macrophages

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M600455-MCP200

21 January 2018

Identifiers

10.1074/MCP.M600455-MCP200

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

1 reference

Europe PubMed Central

5 March 2018

http://europepmc.org/abstract/MED/17507369

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