(Q38118666)

29 August 2017

title

Modification of cysteine residues by cyclopentenone prostaglandins: interplay with redox regulation of protein function (English)

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29 August 2017

Clara L Oeste

1

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29 August 2017

Dolores Pérez-Sala

series ordinal

2

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29 August 2017

publication date

1 July 2013

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Mass Spectrometry Reviews

29 August 2017

published in

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29 August 2017

volume

33

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29 August 2017

issue

2

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29 August 2017

page(s)

110-125

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Identification of actin as a 15-deoxy-Delta12,14-prostaglandin J2 target in neuroblastoma cells: mass spectrometric, computational, and functional approaches to investigate the effect on cytoskeletal derangement.

29 August 2017

cites work

1 reference

Antiproliferative prostaglandins activate heat shock transcription factor

21 January 2018

1 reference

Formation of thiol conjugates of 9-deoxy-delta 9,delta 12(E)-prostaglandin D2 and delta 12(E)-prostaglandin D2.

21 January 2018

1 reference

Reversible post-translational modification of proteins by nitrated fatty acids in vivo

21 January 2018

1 reference

Reactions of some cyclopentenones with selected cysteine derivatives and biological activities of the product thioethers

21 January 2018

1 reference

Oxidation of HRas cysteine thiols by metabolic stress prevents palmitoylation in vivo and contributes to endothelial cell apoptosis

21 January 2018

1 reference

Aldo-keto reductase 1C3 expression in MCF-7 cells reveals roles in steroid hormone and prostaglandin metabolism that may explain its over-expression in breast cancer

21 January 2018

1 reference

Mechanisms of signal transduction mediated by oxidized lipids: the role of the electrophile-responsive proteome

21 January 2018

1 reference

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

21 January 2018

1 reference

Redox regulation of soluble epoxide hydrolase by 15-deoxy-delta-prostaglandin J2 controls coronary hypoxic vasodilation

21 January 2018

1 reference

The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure.

21 January 2018

1 reference

Site-specific protein adducts of 4-hydroxy-2(E)-nonenal in human THP-1 monocytic cells: protein carbonylation is diminished by ascorbic acid.

21 January 2018

1 reference

Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction

21 January 2018

1 reference

15-Deoxi-Delta(12,14)-prostaglandin J2 is a tubulin-binding agent that destabilizes microtubules and induces mitotic arrest.

21 January 2018

1 reference

Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

21 January 2018

1 reference

The cyclopentenone prostaglandin 15-deoxy-delta(12,14)- PGJ2 attenuates the development of colon injury caused by dinitrobenzene sulphonic acid in the rat.

21 January 2018

1 reference

Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12,14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms.

21 January 2018

1 reference

Anti-inflammatory prostanoids: focus on the interactions between electrophile signaling and resolution of inflammation.

21 January 2018

1 reference

A-class prostaglandins: early findings and new perspectives for overcoming tumor chemoresistance

21 January 2018

1 reference

Identification of aldo-keto reductase AKR1B10 as a selective target for modification and inhibition by prostaglandin A(1): implications for antitumoral activity

21 January 2018

1 reference

15d-prostaglandin J2 reduces multiple organ failure caused by wall-fragment of Gram-positive and Gram-negative bacteria

21 January 2018

1 reference

Prostaglandins and leukotrienes: advances in eicosanoid biology

21 January 2018

1 reference

Formation of prostaglandins E2 and D2 via the isoprostane pathway: a mechanism for the generation of bioactive prostaglandins independent of cyclooxygenase

21 January 2018

1 reference

A biotinylated analog of the anti-proliferative prostaglandin A1 allows assessment of PPAR-independent effects and identification of novel cellular targets for covalent modification

21 January 2018

1 reference

Proteomic studies on protein modification by cyclopentenone prostaglandins: expanding our view on electrophile actions.

21 January 2018

1 reference

Differential selectivity of protein modification by the cyclopentenone prostaglandins PGA1 and 15-deoxy-Delta12,14-PGJ2: role of glutathione

21 January 2018

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Delta12-prostaglandin D2 is a potent and selective CRTH2 receptor agonist and causes activation of human eosinophils and Th2 lymphocytes

21 January 2018

1 reference

Study of protein targets for covalent modification by the antitumoral and anti-inflammatory prostaglandin PGA1: focus on vimentin

21 January 2018

1 reference

Inflammatory resolution: new opportunities for drug discovery

21 January 2018

1 reference

All ras proteins are polyisoprenylated but only some are palmitoylated

21 January 2018

1 reference

Cancer chemoprevention mechanisms mediated through the Keap1-Nrf2 pathway

21 January 2018

1 reference

Mechanism of free radical nitric oxide-mediated Ras guanine nucleotide dissociation

21 January 2018

1 reference

The anti-inflammatory prostaglandin 15-deoxy-delta(12,14)-PGJ2 inhibits CRM1-dependent nuclear protein export

21 January 2018

1 reference

LipoCardium: endothelium-directed cyclopentenone prostaglandin-based liposome formulation that completely reverses atherosclerotic lesions

21 January 2018

1 reference

Anti-inflammatory activity of 15-deoxy-delta12,14-PGJ2 and 2-cyclopenten-1-one: role of the heat shock response

21 January 2018

1 reference

Induction of reversible cysteine-targeted protein oxidation by an endogenous electrophile 15-deoxy-delta12,14-prostaglandin J2.

21 January 2018

1 reference

Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome

21 January 2018

1 reference

Transcription factor Nrf2 regulates inflammation by mediating the effect of 15-deoxy-Delta(12,14)-prostaglandin j(2)

21 January 2018

1 reference

15-Deoxy-Delta12,14-prostaglandin J2 inhibits HIV-1 transactivating protein, Tat, through covalent modification.

21 January 2018

1 reference

15-deoxy-Delta(12,14)-prostaglandin J2 inhibits G2-M phase progression in human breast cancer cells via the down-regulation of cyclin B1 and survivin expression

21 January 2018

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Regulation of Nrf2-dependent gene expression by 15-deoxy-Delta12,14-prostaglandin J2.

21 January 2018

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15-deoxy-Delta12,14-prostaglandin J2 as a potential endogenous regulator of redox-sensitive transcription factors

21 January 2018

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The role of 15-deoxy-delta(12,14)-prostaglandin J(2), an endogenous ligand of peroxisome proliferator-activated receptor gamma, in tumor angiogenesis

21 January 2018

1 reference

15-deoxy-Delta12,14-prostaglandin J2 inhibits transcriptional activity of estrogen receptor-alpha via covalent modification of DNA-binding domain

21 January 2018

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15-Deoxy-Delta(12,14)-prostaglandin J(2) stabilizes, but functionally inactivates p53 by binding to the cysteine 277 residue

21 January 2018

1 reference

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds

21 January 2018

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Redox signaling in inflammation: interactions of endogenous electrophiles and mitochondria in cardiovascular disease

21 January 2018

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Cyclopentenone prostaglandins as potential inducers of intracellular oxidative stress

21 January 2018

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15-Deoxy-Delta(12,14)-prostaglandin J(2): the endogenous electrophile that induces neuronal apoptosis

21 January 2018

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A sensitive method for the quantitative measurement of protein thiol modification in response to oxidative stress

21 January 2018

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Induction of the permeability transition and cytochrome c release by 15-deoxy-Delta12,14-prostaglandin J2 in mitochondria

21 January 2018

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Interaction of electrophilic lipid oxidation products with mitochondria in endothelial cells and formation of reactive oxygen species

21 January 2018

1 reference

Differential metabolism of dihomo-gamma-linolenic acid and arachidonic acid by cyclo-oxygenase-1 and cyclo-oxygenase-2: implications for cellular synthesis of prostaglandin E1 and prostaglandin E2

21 January 2018

1 reference

Biphasic effects of 15-deoxy-delta(12,14)-prostaglandin J(2) on glutathione induction and apoptosis in human endothelial cells

21 January 2018

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Cellular mechanisms of redox cell signalling: role of cysteine modification in controlling antioxidant defences in response to electrophilic lipid oxidation products

21 January 2018

1 reference

The glutathionylation of p65 modulates NF-κB activity in 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂-treated endothelial cells

21 January 2018

1 reference

Identification of the reactive cysteine residue in human placenta aldose reductase

21 January 2018

1 reference

Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury.

21 January 2018

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The mitochondrial respiratory complex I is a target for 15-deoxy-delta12,14-prostaglandin J2 action

21 January 2018

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Potentiation of tumor formation by topical administration of 15-deoxy-delta12,14-prostaglandin J2 in a model of skin carcinogenesis

21 January 2018

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15-Deoxy-delta 12,14-prostaglandins D2 and J2 are potent activators of human eosinophils

21 January 2018

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Cyclopentenone prostaglandins induce lymphocyte apoptosis by activating the mitochondrial apoptosis pathway independent of external death receptor signaling.

21 January 2018

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Hydrogen sulfide anion regulates redox signaling via electrophile sulfhydration

21 January 2018

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The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways

21 January 2018

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Accumulation of 15-deoxy-delta(12,14)-prostaglandin J2 adduct formation with Keap1 over time: effects on potency for intracellular antioxidant defence induction

21 January 2018

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The cyclopentenone 15-deoxy-delta 12,14-prostaglandin J2 binds to and activates H-Ras

21 January 2018

1 reference

Multidrug resistance protein (MRP) 1 and MRP3 attenuate cytotoxic and transactivating effects of the cyclopentenone prostaglandin, 15-deoxy-Delta(12,14)prostaglandin J2 in MCF7 breast cancer cells

21 January 2018

1 reference

Glutathione S-transferases (GSTs) inhibit transcriptional activation by the peroxisomal proliferator-activated receptor gamma (PPAR gamma) ligand, 15-deoxy-delta 12,14prostaglandin J2 (15-d-PGJ2).

21 January 2018

1 reference

Protein isoprenylation in biology and disease: general overview and perspectives from studies with genetically engineered animals.

21 January 2018

1 reference

Molecular basis for the direct inhibition of AP-1 DNA binding by 15-deoxy-Delta 12,14-prostaglandin J2.

21 January 2018

1 reference

Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice

21 January 2018

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Glutathionylation of the p50 subunit of NF-kappaB: a mechanism for redox-induced inhibition of DNA binding

21 January 2018

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Observation of two modes of inhibition of human microsomal prostaglandin E synthase 1 by the cyclopentenone 15-deoxy-Δ(12,14)-prostaglandin J(2).

21 January 2018

1 reference

Hematopoietic prostaglandin D2 synthase controls the onset and resolution of acute inflammation through PGD2 and 15-deoxyDelta12 14 PGJ2.

21 January 2018

1 reference

Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective

21 January 2018

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An acylation cycle regulates localization and activity of palmitoylated Ras isoforms

21 January 2018

1 reference

Direct evidence for the covalent modification of glutathione-S-transferase P1-1 by electrophilic prostaglandins: implications for enzyme inactivation and cell survival.

21 January 2018

1 reference

Cyclopentenone prostaglandins with dienone structure promote cross-linking of the chemoresistance-inducing enzyme glutathione transferase P1-1.

21 January 2018

1 reference

Contrary prostaglandins: the opposing roles of PGD2 and its metabolites in leukocyte function.

21 January 2018

1 reference

Antiviral activity of cyclopentenone prostanoids

21 January 2018

1 reference

Molecular pharmacology of the human prostaglandin D2 receptor, CRTH2.

21 January 2018

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Formation and signaling actions of electrophilic lipids

21 January 2018

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Quantification of oxidative posttranslational modifications of cysteine thiols of p21ras associated with redox modulation of activity using isotope-coded affinity tags and mass spectrometry.

21 January 2018

1 reference

Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds

21 January 2018

1 reference

15-deoxy-delta 12,14-prostaglandin J2. A prostaglandin D2 metabolite generated during inflammatory processes

21 January 2018

1 reference

Thioredoxin as a molecular target of cyclopentenone prostaglandins.

21 January 2018

1 reference

15d-PGJ2 induces apoptosis by reactive oxygen species-mediated inactivation of Akt in leukemia and colorectal cancer cells and shows in vivo antitumor activity

21 January 2018

1 reference

Alpha,beta-unsaturated ketone is a core moiety of natural ligands for covalent binding to peroxisome proliferator-activated receptor gamma.

21 January 2018

1 reference

Multidrug resistance-associated protein 1 mediates 15-deoxy-Δ(12,14)-prostaglandin J2-induced expression of glutamate cysteine ligase expression via Nrf2 signaling in human breast cancer cells

21 January 2018

1 reference

Regulation of aldose reductase and the polyol pathway activity by nitric oxide

21 January 2018

1 reference

Identification of novel protein targets for modification by 15-deoxy-Delta12,14-prostaglandin J2 in mesangial cells reveals multiple interactions with the cytoskeleton

21 January 2018

1 reference

Cyclopentenone prostaglandins: new insights on biological activities and cellular targets

21 January 2018

1 reference

15-deoxy-delta 12,14-prostaglandin J2 inhibits multiple steps in the NF-kappa B signaling pathway.

21 January 2018

1 reference

A monoclonal antibody specific for Δ12-prostaglandin J2 and its utilization in the immunological assay in cell culture system of adipocytes

21 January 2018

1 reference

Generation of monoclonal antibody for 15-deoxy-Δ¹²,¹⁴-prostaglandin J₂ and development of enzyme-linked immunosorbent assay for its quantification in culture medium of adipocytes

21 January 2018

1 reference

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system

21 January 2018

1 reference

Nitro-fatty acids occur in human plasma in the picomolar range: a targeted nitro-lipidomics GC-MS/MS study

21 January 2018

1 reference

The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages

21 January 2018

1 reference

Structural insight into PPARgamma activation through covalent modification with endogenous fatty acids

21 January 2018

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Heat shock response modulators as therapeutic tools for diseases of protein conformation

21 January 2018

1 reference

Delta12-prostaglandin J2 as a product and ligand of human serum albumin: formation of an unusual covalent adduct at His146

21 January 2018

1 reference

Prostaglandin-induced neurodegeneration is associated with increased levels of oxidative markers and reduced by a mixture of antioxidants

21 January 2018

1 reference

The Nrf2-Keap1-ARE signaling pathway: The regulation and dual function of Nrf2 in cancer.

21 January 2018

1 reference

Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2).

21 January 2018

1 reference

HSF1-dependent upregulation of Hsp70 by sulfhydryl-reactive inducers of the KEAP1/NRF2/ARE pathway

21 January 2018

1 reference

Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-Delta(12,14)-prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways

21 January 2018

1 reference

Selective binding of the fluorescent dye 1-anilinonaphthalene-8-sulfonic acid to peroxisome proliferator-activated receptor gamma allows ligand identification and characterization

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/MAS.21383

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29 August 2017

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