(Q38119156)

29 August 2017

title

Targeting urocortin signaling pathways to enhance cardioprotection: is it time to move from bench to bedside? (English)

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29 August 2017

13

Giuseppe Faggian

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29 August 2017

9

Jagat Narula

1 reference

29 August 2017

Francesco Onorati

1

1 reference

29 August 2017

Carol Chen-Scarabelli

2

1 reference

29 August 2017

Richard Knight

3

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29 August 2017

Anastasis Stephanou

4

1 reference

29 August 2017

Bibhu Mohanti

5

1 reference

29 August 2017

Francesco Santini

6

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29 August 2017

Maddalena Tessari

7

1 reference

29 August 2017

Annapoorna Kini

8

1 reference

29 August 2017

Louis Saravolatz

10

1 reference

29 August 2017

Alessandro Mazzucco

11

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29 August 2017

Tiziano Scarabelli

12

1 reference

29 August 2017

publication date

1 October 2013

1 reference

Cardiovascular Drugs and Therapy

29 August 2017

published in

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29 August 2017

volume

27

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29 August 2017

issue

5

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29 August 2017

page(s)

451-463

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Mechanisms of action and clinical implications of cardiac urocortin: a journey from the heart to the systemic circulation, with a stopover in the mitochondria

29 August 2017

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21 January 2018

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Characterization of a 41-Residue Ovine Hypothalamic Peptide That Stimulates Secretion of Corticotropin and β-Endorphin

21 January 2018

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A role for corticotropin releasing factor and urocortin in behavioral responses to stressors.

21 January 2018

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Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor

21 January 2018

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Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin 3 regulates glucose-stimulated insulin secretion and energy homeostasis

21 January 2018

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Common and divergent structural features of a series of corticotropin releasing factor-related peptides

21 January 2018

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Urocortin: a protective peptide that targets both the myocardium and vasculature

21 January 2018

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Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2.

21 January 2018

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Insights into mechanisms of corticotropin-releasing hormone receptor signal transduction.

21 January 2018

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The role of phosphoinositide-3 kinase and PTEN in cardiovascular physiology and disease

21 January 2018

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Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)

21 January 2018

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Opposing roles of delta and epsilonPKC in cardiac ischemia and reperfusion: targeting the apoptotic machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Analysis of Ras-dependent signals that prevent caspase-3 activation and apoptosis induced by cytokine deprivation in hematopoietic cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Regulation of cell death protease caspase-9 by phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Activation of protein kinase B/Akt by urocortin is essential for its ability to protect cardiac cells against hypoxia/reoxygenation-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

MAPK signalling: ERK5 versus ERK1/2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

New directions for protecting the heart against ischaemia-reperfusion injury: targeting the Reperfusion Injury Salvage Kinase (RISK)-pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin protects against ischemic and reperfusion injury via a MAPK-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin increases the expression of heat shock protein 90 in rat cardiac myocytes in a MEK1/2-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin-II and urocortin-III are cardioprotective against ischemia reperfusion injury: an essential endogenous cardioprotective role for corticotropin releasing factor receptor type 2 in the murine heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Hypertrophic effects of urocortin homologous peptides are mediated via activation of the Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

A selective epsilon-protein kinase C antagonist inhibits protection of cardiac myocytes from hypoxia-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Functional proteomic analysis of protein kinase C epsilon signaling complexes in the normal heart and during cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Cardioprotection mediated by sphingosine-1-phosphate and ganglioside GM-1 in wild-type and PKC epsilon knockout mouse hearts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Protein kinase C theta and epsilon promote T-cell survival by a rsk-dependent phosphorylation and inactivation of BAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Mitochondrial PKCepsilon and MAPK form signaling modules in the murine heart: enhanced mitochondrial PKCepsilon-MAPK interactions and differential MAPK activation in PKCepsilon-induced cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin prevents mitochondrial permeability transition in response to reperfusion injury indirectly by reducing oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin 2 suppresses host resistance to Listeria monocytogenes infection via up-regulation of interleukin-10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

K(ATP) channel gene expression is induced by urocortin and mediates its cardioprotective effect.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

New targets of urocortin-mediated cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

21 January 2018

Glutaredoxin systems.

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Molecular basis for Rac2 regulation of phagocyte NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

AMPK alterations in cardiac physiology and pathology: enemy or ally?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Dual cardiac contractile effects of the alpha2-AMPK deletion in low-flow ischemia and reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Nuclear translocation of X-linked inhibitor of apoptosis (XIAP) determines cell fate after hypoxia ischemia in neonatal brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

AMP-activated protein kinase protects cardiomyocytes against hypoxic injury through attenuation of endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin promotes hemodynamic and bioenergetic recovery and improves cell survival in the isolated rat heart exposed to ischemia/reperfusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Mitochondrial permeability transition pore opening during myocardial reperfusion--a target for cardioprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Does antegrade blood cardioplegia alone provide adequate myocardial protection in patients with left main stem disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Clinical implications of apoptosis in ischemic myocardium

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Turning necrosis into apoptosis: the exacting task that can enhance survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Endothelial apoptosis is induced by serum of patients after cardiopulmonary bypass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Endogenous urocortins reduce vascular tone and renin-aldosterone/endothelin activity in experimental heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Meta-analysis of corticosteroid treatment in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Nonsteroidal antiinflammatory drugs after acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

C-reactive protein and complement are important mediators of tissue damage in acute myocardial infarction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Reduction of myocardial infarct size by fluvastatin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Myocardial infarct expansion, infarct extension, and reinfarction: pathophysiologic concepts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Measurement of the ADP:ATP ratio in human leukaemic cell lines can be used as an indicator of cell viability, necrosis and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Serine/threonine protein kinases and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Akt promotes survival of cardiomyocytes in vitro and protects against ischemia-reperfusion injury in mouse heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

The phosphatidylinositol 3-kinase (PI3K)-Akt pathway suppresses Bax translocation to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

A phosphatidylinositol 3-kinase/Akt pathway promotes translocation of Mdm2 from the cytoplasm to the nucleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

The mitochondrial death/life regulator in apoptosis and necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Preconditioning the Myocardium: From Cellular Physiology to Clinical Cardiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Bcl-2 targets the protein kinase Raf-1 to mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Beneficial hemodynamic, endocrine, and renal effects of urocortin in experimental heart failure: comparison with normal sheep

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Integrated hemodynamic, hormonal, and renal actions of urocortin 2 in normal and paced sheep: beneficial effects in heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Plasma urocortin in human systolic heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Circulating levels of stress associated peptide Urocortin in heart failure patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Plasma urocortin in acute myocardial infarction patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Plasma urocortin 1 in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin-1 infusion in normal humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Effect of urocortin 1 infusion in humans with stable congestive cardiac failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin 2 infusion in human heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin-2 induces vasorelaxation of coronary arteries isolated from patients with heart failure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Warm-blood cardioplegic arrest induces selective mitochondrial translocation of protein kinase Cepsilon followed by interaction with 6.1 inwardly rectifying potassium channel subunit in viable myocytes overexpressing urocortin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

Urocortin-induced relaxation in the human internal mammary artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10557-013-6468-7

10.1007/S10557-013-6468-7

21 January 2018

Identifiers

DOI

1 reference

29 August 2017

1 reference