(Q38119533)

29 August 2017

Emerging role of the scaffolding protein Dlg1 in vesicle trafficking (English)

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29 August 2017

Laurence Walch

1

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PubMed ID

23829493

29 August 2017

language of work or name

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1 September 2013

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29 August 2017

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29 August 2017

14

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29 August 2017

9

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29 August 2017

964-973

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Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions

29 August 2017

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Cloning and characterization of hdlg: the human homologue of the Drosophila discs large tumor suppressor binds to protein 4.1

21 January 2018

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Functional analysis of the guanylate kinase-like domain in the synapse-associated protein SAP97.

21 January 2018

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The emerging contribution of sequence context to the specificity of protein interactions mediated by PDZ domains

21 January 2018

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The tetrameric L27 domain complex as an organization platform for supramolecular assemblies

21 January 2018

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SMART, a simple modular architecture research tool: identification of signaling domains

21 January 2018

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Human homologue of the Drosophila discs large tumor suppressor protein forms an oligomer in solution. Identification of the self-association site

21 January 2018

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Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking

21 January 2018

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Different isoforms of synapse-associated protein, SAP97, are expressed in the heart and have distinct effects on the voltage-gated K+ channel Kv1.5

21 January 2018

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Synapse-associated protein-97 mediates alpha-secretase ADAM10 trafficking and promotes its activity

21 January 2018

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GAKIN, a novel kinesin-like protein associates with the human homologue of the Drosophila discs large tumor suppressor in T lymphocytes

21 January 2018

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GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules

21 January 2018

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Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins

21 January 2018

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p38gamma regulates the localisation of SAP97 in the cytoskeleton by modulating its interaction with GKAP

21 January 2018

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Two independent domains of hDlg are sufficient for subcellular targeting: the PDZ1-2 conformational unit and an alternatively spliced domain

21 January 2018

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The distribution and function of alternatively spliced insertions in hDlg

21 January 2018

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Identification of brain-specific splicing variants of the hDLG1 gene and altered splicing in neuroblastoma cell lines

21 January 2018

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The effector domain of human Dlg tumor suppressor acts as a switch that relieves autoinhibition of kinesin-3 motor GAKIN/KIF13B.

21 January 2018

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Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

21 January 2018

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Organizing a functional junctional complex requires specific domains of the Drosophila MAGUK Discs large

21 January 2018

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PDZ proteins and polarity: functions from the fly.

21 January 2018

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Functional expression of rat synapse-associated proteins SAP97 and SAP102 in Drosophila dlg-1 mutants: effects on tumor suppression and synaptic bouton structure.

21 January 2018

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Cell polarity proteins: common targets for tumorigenic human viruses

21 January 2018

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Differential expression of the human homologue of drosophila discs large oncosuppressor in histologic samples from human papillomavirus-associated lesions as a marker for progression to malignancy

21 January 2018

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Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

21 January 2018

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Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression.

21 January 2018

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PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line

21 January 2018

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Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

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Changes in expression of the human homologue of the Drosophila discs large tumour suppressor protein in high-grade premalignant cervical neoplasias

21 January 2018

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Craniofacial dysmorphogenesis including cleft palate in mice with an insertional mutation in the discs large gene

21 January 2018

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Requirement of PDZ-containing proteins for cell cycle regulation and differentiation in the mouse lens epithelium

21 January 2018

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Cell-autonomous requirements for Dlg-1 for lens epithelial cell structure and fiber cell morphogenesis

21 January 2018

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Human homolog of disc-large is required for adherens junction assembly and differentiation of human intestinal epithelial cells

21 January 2018

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The MAGUK protein MPP7 binds to the polarity protein hDlg1 and facilitates epithelial tight junction formation

21 January 2018

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Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases

21 January 2018

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DLGS97/SAP97 is developmentally upregulated and is required for complex adult behaviors and synapse morphology and function.

21 January 2018

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Synaptic clustering of the cell adhesion molecule fasciclin II by discs-large and its role in the regulation of presynaptic structure

21 January 2018

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Synaptic clustering of Fascilin II and Shaker: essential targeting sequences and role of Dlg.

21 January 2018

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Synaptic trafficking of glutamate receptors by MAGUK scaffolding proteins

21 January 2018

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PDZ domain proteins of synapses

21 January 2018

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Cdc42 and Par6-PKCzeta regulate the spatially localized association of Dlg1 and APC to control cell polarization.

21 January 2018

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Dlg1 binds GKAP to control dynein association with microtubules, centrosome positioning, and cell polarity.

21 January 2018

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Maintenance and modulation of T cell polarity

21 January 2018

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Ezrin tunes T-cell activation by controlling Dlg1 and microtubule positioning at the immunological synapse.

21 January 2018

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Human homologue of the Drosophila discs large tumor suppressor binds to p56lck tyrosine kinase and Shaker type Kv1.3 potassium channel in T lymphocytes

21 January 2018

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Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors

21 January 2018

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Dlgh1 coordinates actin polymerization, synaptic T cell receptor and lipid raft aggregation, and effector function in T cells

21 January 2018

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Protein trafficking in polarized cells

21 January 2018

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Apical trafficking in epithelial cells: signals, clusters and motors

21 January 2018

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Coordinated protein sorting, targeting and distribution in polarized cells

21 January 2018

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Signal-mediated, AP-1/clathrin-dependent sorting of transmembrane receptors to the somatodendritic domain of hippocampal neurons

21 January 2018

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A novel clathrin adaptor complex mediates basolateral targeting in polarized epithelial cells

21 January 2018

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Differential recognition of tyrosine-based basolateral signals by AP-1B subunit mu1B in polarized epithelial cells

21 January 2018

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Temporal association of the N- and O-linked glycosylation events and their implication in the polarized sorting of intestinal brush border sucrase-isomaltase, aminopeptidase N, and dipeptidyl peptidase IV.

21 January 2018

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Specific N-glycans direct apical delivery of transmembrane, but not soluble or glycosylphosphatidylinositol-anchored forms of endolyn in Madin-Darby canine kidney cells

21 January 2018

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N-glycans as apical sorting signals in epithelial cells

21 January 2018

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The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells

21 January 2018

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Oligomerization is a specific requirement for apical sorting of glycosyl-phosphatidylinositol-anchored proteins but not for non-raft-associated apical proteins

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Recycling endosomes can serve as intermediates during transport from the Golgi to the plasma membrane of MDCK cells

21 January 2018

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Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells

21 January 2018

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Involvement of microtubule motors in basolateral and apical transport in kidney cells.

21 January 2018

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A novel motor, KIF13A, transports mannose-6-phosphate receptor to plasma membrane through direct interaction with AP-1 complex

21 January 2018

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Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport

21 January 2018

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Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites

21 January 2018

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Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells

21 January 2018

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Endogenous syntaxins 2, 3 and 4 exhibit distinct but overlapping patterns of expression at the hepatocyte plasma membrane

21 January 2018

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Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells

21 January 2018

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The role of syntaxins in the specificity of vesicle targeting in polarized epithelial cells

21 January 2018

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SAP97 directs the localization of Kv4.2 to spines in hippocampal neurons: regulation by CaMKII

21 January 2018

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PSD-95 and SAP97 exhibit distinct mechanisms for regulating K(+) channel surface expression and clustering

21 January 2018

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Dual role of CaMKII-dependent SAP97 phosphorylation in mediating trafficking and insertion of NMDA receptor subunit NR2A.

21 January 2018

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SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway.

21 January 2018

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A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels

21 January 2018

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A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia

21 January 2018

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Selective binding of synapse-associated protein 97 to GluR-A alpha-amino-5-hydroxy-3-methyl-4-isoxazole propionate receptor subunit is determined by a novel sequence motif

21 January 2018

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Disruption of the interaction between myosin VI and SAP97 is associated with a reduction in the number of AMPARs at hippocampal synapses

21 January 2018

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Myosin VI is an actin-based motor that moves backwards

21 January 2018

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How are the cellular functions of myosin VI regulated within the cell?

21 January 2018

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Myosin VI is required for sorting of AP-1B-dependent cargo to the basolateral domain in polarized MDCK cells

21 January 2018

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Myosin VI and optineurin are required for polarized EGFR delivery and directed migration

21 January 2018

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Myosin VI and its binding partner optineurin are involved in secretory vesicle fusion at the plasma membrane.

21 January 2018

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Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells

21 January 2018

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Dlg1, Sec8, and Mtmr2 regulate membrane homeostasis in Schwann cell myelination

21 January 2018

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Discs large 1 (Dlg1) scaffolding protein participates with clathrin and adaptator protein complex 1 (AP-1) in forming Weibel-Palade bodies of endothelial cells

21 January 2018

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Biochemistry and genetics of von Willebrand factor

21 January 2018

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An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells.

21 January 2018

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Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering

21 January 2018

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Regulated transport of the glucose transporter GLUT4

21 January 2018

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Regulation of glucose transport by insulin: traffic control of GLUT4.

21 January 2018

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Postsynaptic membrane addition depends on the Discs-Large-interacting t-SNARE Gtaxin

21 January 2018

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Syntaxin 18, a SNAP receptor that functions in the endoplasmic reticulum, intermediate compartment, and cis-Golgi vesicle trafficking

21 January 2018

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Regulation of the hDlg/hScrib/Hugl-1 tumour suppressor complex

21 January 2018

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Molecular mechanism and physiological functions of clathrin-mediated endocytosis

21 January 2018

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Mechanisms of endocytosis

21 January 2018

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Dynamin self-assembles into rings suggesting a mechanism for coated vesicle budding

21 January 2018

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Cytosol- and clathrin-dependent stimulation of endocytosis in vitro by purified adaptors

21 January 2018

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Tubular membrane invaginations coated by dynamin rings are induced by GTP-gamma S in nerve terminals

21 January 2018

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Clathrin-mediated endocytosis in AP-2-depleted cells

21 January 2018

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A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis

21 January 2018

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Differential binding of the AP-2 adaptor complex and PSD-95 to the C-terminus of the NMDA receptor subunit NR2B regulates surface expression

21 January 2018

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Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins

21 January 2018

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Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling and networking

21 January 2018

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The Hrs/STAM complex in the downregulation of receptor tyrosine kinases

21 January 2018

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Hrs recruits clathrin to early endosomes

21 January 2018

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

21 January 2018

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ESCRT proteins: Double-edged regulators of cellular signaling

21 January 2018

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An essential role of Hrs/Vps27 in endosomal cholesterol trafficking

21 January 2018

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An association analysis of synapse-associated protein 97 (SAP97) gene in schizophrenia

21 January 2018

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Further evidence for a male-selective genetic association of synapse-associated protein 97 (SAP97) gene with schizophrenia

21 January 2018

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Evidence for abnormal forward trafficking of AMPA receptors in frontal cortex of elderly patients with schizophrenia

21 January 2018

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Selective reduction of a PDZ protein, SAP-97, in the prefrontal cortex of patients with chronic schizophrenia

21 January 2018

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SAP97-mediated local trafficking is altered in Alzheimer disease patients' hippocampus.

21 January 2018

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Cell biology of membrane trafficking in human disease

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/TRA.12089

1 reference

29 August 2017

1 reference

PubMed ID

23829493