(Q38121858)

29 August 2017

Biochemical and molecular mechanisms for the association between obesity, chronic inflammation, and breast cancer (English)

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29 August 2017

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Linda Vona-Davis

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29 August 2017

David P Rose

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29 August 2017

16 July 2013

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29 August 2017

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29 August 2017

40

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29 August 2017

1

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29 August 2017

1-12

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Estimates of the cancer incidence and mortality in Europe in 2006.

29 August 2017

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Pooled analysis of prospective cohort studies on height, weight, and breast cancer risk

21 January 2018

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Influence of obesity on breast cancer receptor status and prognosis

21 January 2018

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Adipose inflammation, insulin resistance, and cardiovascular disease

21 January 2018

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Chronic inflammation links cardiovascular, metabolic and renal diseases

21 January 2018

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NF-kappaB: linking inflammation and immunity to cancer development and progression

21 January 2018

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Inflammation and increased aromatase expression occur in the breast tissue of obese women with breast cancer

21 January 2018

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Growth signals, inflammation, and vascular perturbations: mechanistic links between obesity, metabolic syndrome, and cancer

21 January 2018

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Normal breast tissue of obese women is enriched for macrophage markers and macrophage-associated gene expression

21 January 2018

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Central obesity and breast cancer risk: a systematic review.

21 January 2018

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Obesity, adipocytokines, and insulin resistance in breast cancer

21 January 2018

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Molecular links between obesity and breast cancer

21 January 2018

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Obesity and prognosis of breast cancer

21 January 2018

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Adiposity, the metabolic syndrome, and breast cancer in African-American and white American women

21 January 2018

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Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland

21 January 2018

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Circulating steroid hormone concentrations in postmenopausal women in relation to body size and composition

21 January 2018

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Endogenous sex hormones and breast cancer in postmenopausal women: reanalysis of nine prospective studies

21 January 2018

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Prognostic effect of estrogen receptor status across age in primary breast cancer

21 January 2018

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Leptin Enhances, via AP-1, Expression of Aromatase in the MCF-7 Cell Line

21 January 2018

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Development and evolution of therapies targeted to the estrogen receptor for the treatment and prevention of breast cancer

21 January 2018

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Effect of body mass index on recurrences in tamoxifen and anastrozole treated women: an exploratory analysis from the ATAC trial

21 January 2018

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Anthropometric measures, endogenous sex steroids and breast cancer risk in postmenopausal women: a study within the EPIC cohort.

21 January 2018

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Risk Factors for Hormone Receptor-Defined Breast Cancer in Postmenopausal Women

21 January 2018

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Body weight and incidence of breast cancer defined by estrogen and progesterone receptor status--a meta-analysis

21 January 2018

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Insulin- and obesity-related variables in early-stage breast cancer: correlations and time course of prognostic associations.

21 January 2018

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The cellular and molecular mechanisms by which insulin influences breast cancer risk and progression

21 January 2018

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Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression

21 January 2018

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Adipose tissue, adipokines, and inflammation

21 January 2018

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21 January 2018

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21 January 2018

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Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells.

21 January 2018

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Cellular and molecular crosstalk between leptin receptor and estrogen receptor-{alpha} in breast cancer: molecular basis for a novel therapeutic setting

21 January 2018

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Efficacy of a leptin receptor antagonist peptide in a mouse model of triple-negative breast cancer

21 January 2018

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Leptin utilizes Jun N-terminal kinases to stimulate the invasion of MCF-7 breast cancer cells

21 January 2018

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Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.

21 January 2018

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Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer

21 January 2018

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Molecular markers of epithelial-to-mesenchymal transition are associated with tumor aggressiveness in breast carcinoma

21 January 2018

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Enhanced NF kappa B and AP-1 transcriptional activity associated with antiestrogen resistant breast cancer

21 January 2018

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Triple-negative breast cancer: clinical features and patterns of recurrence

21 January 2018

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Triple-negative breast cancer and obesity in a rural Appalachian population

21 January 2018

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Epidemiology of breast cancer subtypes in two prospective cohort studies of breast cancer survivors

21 January 2018

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Adiponectin differentially regulates cytokines in porcine macrophages

21 January 2018

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Adiponectin inhibits LPS-induced NF-kappaB activation and IL-6 production and increases PPARgamma2 expression in adipocytes

21 January 2018

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Obesity and breast cancer: status of leptin and adiponectin in pathological processes.

21 January 2018

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Molecular mechanisms of leptin and adiponectin in breast cancer

21 January 2018

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Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells

21 January 2018

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LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells

21 January 2018

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Adiponectin modulates the glycogen synthase kinase-3beta/beta-catenin signaling pathway and attenuates mammary tumorigenesis of MDA-MB-231 cells in nude mice.

21 January 2018

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Wnt signaling and breast cancer

21 January 2018

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Wnt/β-catenin signaling and disease

21 January 2018

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Use of MMTV-Wnt-1 transgenic mice for studying the genetic basis of breast cancer

21 January 2018

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Adipogenesis and WNT signalling

21 January 2018

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Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity.

21 January 2018

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Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome.

21 January 2018

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β-Catenin pathway activation in breast cancer is associated with triple-negative phenotype but not with CTNNB1 mutation

21 January 2018

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Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival

21 January 2018

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Insulin-stimulated cell growth in insulin receptor substrate-1-deficient ZR-75-1 cells is mediated by a phosphatidylinositol-3-kinase-independent pathway

21 January 2018

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Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: possible role of obesity-related stimuli.

21 January 2018

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Insulin-dependent leptin expression in breast cancer cells.

21 January 2018

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Prospective study on the role of glucose metabolism in breast cancer occurrence.

21 January 2018

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Association between TCF7L2 gene polymorphisms and susceptibility to type 2 diabetes mellitus: a large Human Genome Epidemiology (HuGE) review and meta-analysis

21 January 2018

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Glucose-induced β-catenin acetylation enhances Wnt signaling in cancer.

21 January 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

21 January 2018

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Epithelial-mesenchymal transition and breast cancer: role, molecular mechanisms and clinical impact.

21 January 2018

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Leptin-induced epithelial-mesenchymal transition in breast cancer cells requires β-catenin activation via Akt/GSK3- and MTA1/Wnt1 protein-dependent pathways

21 January 2018

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Invasive capacity and regulation of urokinase-type plasminogen activator in estrogen receptor (ER)-negative MDA-MB-231 human breast cancer cells, and a transfectant (S30) stably expressing ER.

21 January 2018

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Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype

21 January 2018

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Epithelial-mesenchymal transition in breast cancer correlates with high histological grade and triple-negative phenotype.

21 January 2018

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PKCα and ERβ Are Associated with Triple-Negative Breast Cancers in African American and Caucasian Patients

21 January 2018

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Matrix metalloproteinase-2 (MMP-2) and MMP-9 expression in invasive ductal carcinoma of the breast

21 January 2018

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Cytokines, obesity, and cancer: new insights on mechanisms linking obesity to cancer risk and progression

21 January 2018

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Dietary energy balance modulates epithelial-to-mesenchymal transition and tumor progression in murine claudin-low and basal-like mammary tumor models

21 January 2018

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21 January 2018

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Genes involved in the immediate early response and epithelial-mesenchymal transition are regulated by adipocytokines in the female reproductive tract.

21 January 2018

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Angiogenesis, adipokines and breast cancer

21 January 2018

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Angiogenesis and development of adipose tissue

21 January 2018

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Angiogenesis inhibitor, TNP-470, prevents diet-induced and genetic obesity in mice

21 January 2018

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Leptin signaling promotes the growth of mammary tumors and increases the expression of vascular endothelial growth factor (VEGF) and its receptor type two (VEGF-R2)

21 January 2018

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Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice

21 January 2018

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Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis

21 January 2018

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Macrophages and angiogenesis: a role for Wnt signaling

21 January 2018

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Tumor-associated macrophages press the angiogenic switch in breast cancer.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BIOF.1109

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29 August 2017

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PubMed ID

23857944