(Q38123773)

29 August 2017

Phosphatidylinositol 3-phosphate, a lipid that regulates membrane dynamics, protein sorting and cell signalling (English)

1 reference

29 August 2017

0 references

3

Harald Stenmark

1 reference

29 August 2017

Kay O Schink

1

1 reference

PubMed ID

23881848

29 August 2017

Camilla Raiborg

series ordinal

2

1 reference

PubMed ID

23881848

29 August 2017

language of work or name

English

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publication date

24 July 2013

1 reference

29 August 2017

1 reference

29 August 2017

35

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29 August 2017

10

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29 August 2017

900-912

1 reference

The phosphoinositide 3-kinase pathway

29 August 2017

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Regulation and cellular functions of class II phosphoinositide 3-kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The regulation and function of Class III PI3Ks: novel roles for Vps34.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Acetylated hsp70 and KAP1-mediated Vps34 SUMOylation is required for autophagosome creation in autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Nedd4-dependent lysine-11-linked polyubiquitination of the tumour suppressor Beclin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphatidylinositol-3-OH kinases are Rab5 effectors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Intracellular trafficking and turnover of phosphatidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosome related functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Myotubularin phosphoinositide phosphatases in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Endosomal localization of the autoantigen EEA1 is mediated by a zinc-binding FYVE finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A functional PtdIns(3)P-binding motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

FYVE fingers bind PtdIns(3)P

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The phosphatidylinositol 3-phosphate-binding FYVE finger

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Conditional peripheral membrane proteins: facing up to limited specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Multivalent endosome targeting by homodimeric EEA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

How Atg18 and the WIPIs sense phosphatidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Eap45 in mammalian ESCRT-II binds ubiquitin via a phosphoinositide-interacting GLUE domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The PI(3)P interactome from a colon cancer cell.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Structural Basis for Endosomal Targeting by FYVE Domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Time-resolved ultrastructural detection of phosphatidylinositol 3-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Identification of small molecule inhibitors of phosphatidylinositol 3-kinase and autophagy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Shaping Development of Autophagy Inhibitors with the Structure of the Lipid Kinase Vps34

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Compartmental signal modulation: Endosomal phosphatidylinositol 3-phosphate controls endosome morphology and selective cargo sorting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

PI3P signaling regulates receptor sorting but not transport in the endosomal pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Class III phosphatidylinositol 3-kinase and its catalytic product PtdIns3P in regulation of endocytic membrane traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

rab5 controls early endosome fusion in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

EEA1 links PI(3)K function to Rab5 regulation of endosome fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Rabenosyn-5, a novel Rab5 effector, is complexed with hVPS45 and recruited to endosomes through a FYVE finger domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Modulation of receptor recycling and degradation by the endosomal kinesin KIF16B

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Receptor downregulation and multivesicular-body sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Ubc4/5 and c-Cbl continue to ubiquitinate EGF receptor after internalization to facilitate polyubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Misfolding diverts CFTR from recycling to degradation: quality control at early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Ubiquitination of alpha 5 beta 1 integrin controls fibroblast migration through lysosomal degradation of fibronectin-integrin complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Hrs controls sorting of the epithelial Na+ channel between endosomal degradation and recycling pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Molecular mechanism of multivesicular body biogenesis by ESCRT complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Hrs recruits clathrin to early endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

TSG101 interaction with HRS mediates endosomal trafficking and receptor down-regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Vps27 recruits ESCRT machinery to endosomes during MVB sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Membrane scission by the ESCRT-III complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

SNX-BAR proteins in phosphoinositide-mediated, tubular-based endosomal sorting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Sorting nexin-1 mediates tubular endosome-to-TGN transport through coincidence sensing of high- curvature membranes and 3-phosphoinositides

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Autophagy fights disease through cellular self-digestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

3-Methyladenine: specific inhibitor of autophagic/lysosomal protein degradation in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Molecular dissection of autophagy: two ubiquitin-like systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Two distinct Vps34 phosphatidylinositol 3-kinase complexes function in autophagy and carboxypeptidase Y sorting in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Where do they come from? Insights into autophagosome formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Autophagosomes form at ER-mitochondria contact sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Membrane transport in Caenorhabditis elegans: an essential role for VPS34 at the nuclear membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The Atg18-Atg2 complex is recruited to autophagic membranes via phosphatidylinositol 3-phosphate and exerts an essential function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

WIPI-1alpha (WIPI49), a member of the novel 7-bladed WIPI protein family, is aberrantly expressed in human cancer and is linked to starvation-induced autophagy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein Alfy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Class II phosphoinositide 3-kinase regulates exocytosis of insulin granules in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Cytokinesis: placing and making the final cut.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Divide and ProsPer: the emerging role of PtdIns3P in cytokinesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

PtdIns(3)P controls cytokinesis through KIF13A-mediated recruitment of FYVE-CENT to the midbody

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A phosphatidylinositol 3-kinase class III sub-complex containing VPS15, VPS34, Beclin 1, UVRAG and BIF-1 regulates cytokinesis and degradative endocytic traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

A tumor-associated mutation of FYVE-CENT prevents its interaction with Beclin 1 and interferes with cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Activation of the phosphatidylinositol 3-kinase Vps34 by a G protein alpha subunit at the endosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Class II phosphoinositide 3-kinase defines a novel signaling pathway in cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The role of PI3Ks in the regulation of the neutrophil NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The role of phosphoinositides and phosphorylation in regulation of NADPH oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Amino acids mediate mTOR/raptor signaling through activation of class 3 phosphatidylinositol 3OH-kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

mTOR: from growth signal integration to cancer, diabetes and ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Early endosomal regulation of Smad-dependent signaling in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Endofin acts as a Smad anchor for receptor activation in BMP signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

SARA is dispensable for functional TGF-β signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Endofin recruits clathrin to early endosomes via TOM1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Myotubularin lipid phosphatase binds the hVPS15/hVPS34 lipid kinase complex on endosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Reconstitution of Rab- and SNARE-dependent membrane fusion by synthetic endosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

UCSF Chimera--a visualization system for exploratory research and analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Spatiotemporal control of endocytosis by phosphatidylinositol-3,4-bisphosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Activation of membrane-permeant caged PtdIns(3)P induces endosomal fusion in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

The PtdIns3P-Binding Protein Phafin 2 Mediates Epidermal Growth Factor Receptor Degradation by Promoting Endosome Fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

Transport of phosphatidylinositol 3-phosphate into the vacuole via autophagic membranes in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201300064

21 January 2018

Identifiers

DOI

10.1002/BIES.201300064

1 reference

29 August 2017

1 reference

PubMed ID

23881848