(Q38129925)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

title

Therapeutic targets associated to E-cadherin dysfunction in gastric cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Raquel Seruca

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Patrícia Carneiro

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Joana Figueiredo

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Renata Bordeira-Carriço

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

M S Fernandes

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

Joana Carvalho

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

author name string

Maria Sofia Fernandes

4

1 reference

29 August 2017

language of work or name

English

0 references

publication date

19 August 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

Expert Opinion on Therapeutic Targets

7 March 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

volume

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

page(s)

1187-1201

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

issue

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

Changing neighbours, changing behaviour: cell adhesion molecule-mediated signalling during tumour progression

7 March 2020

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A Genetic Screen in Drosophila for Metastatic Behavior

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The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene

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Germline CDH1 deletions in hereditary diffuse gastric cancer families

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Quantification of epigenetic and genetic 2nd hits in CDH1 during hereditary diffuse gastric cancer syndrome progression.

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Inactivation of the E-cadherin gene in sporadic diffuse-type gastric cancer

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21 January 2018

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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

21 January 2018

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21 January 2018

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Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study

21 January 2018

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21 January 2018

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Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cadherins and cancer: how does cadherin dysfunction promote tumor progression?

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E-cadherin gene re-expression in chronic lymphocytic leukemia cells by HDAC inhibitors

21 January 2018

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Expression profiling of stem cell-related genes in neoadjuvant-treated gastric cancer: a NOTCH2, GSK3B and β-catenin gene signature predicts survival

21 January 2018

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Acute WNT signalling activation perturbs differentiation within the adult stomach and rapidly leads to tumour formation

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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MiR-214 regulate gastric cancer cell proliferation, migration and invasion by targeting PTEN.

21 January 2018

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21 January 2018

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21 January 2018

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Induction of polarized cell-cell association and retardation of growth by activation of the E-cadherin-catenin adhesion system in a dispersed carcinoma line

21 January 2018

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Targeting Src family kinases in anti-cancer therapies: turning promise into triumph

21 January 2018

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Suppression of E-cadherin function drives the early stages of Ras-induced squamous cell carcinoma through upregulation of FAK and Src.

21 January 2018

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Src/FAK-mediated regulation of E-cadherin as a mechanism for controlling collective cell movement: insights from in vivo imaging

21 January 2018

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Expression and clinical significance of focal adhesion kinase in the two distinct histological types, intestinal and diffuse, of human gastric adenocarcinoma.

21 January 2018

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Focal adhesion kinase (FAK) gene amplification and its clinical implications in gastric cancer

21 January 2018

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Phosphorylation of focal adhesion kinase at Tyr397 in gastric carcinomas and its clinical significance

21 January 2018

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Signaling through focal adhesion kinase

21 January 2018

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Hedgehog signaling in animal development: paradigms and principles

21 January 2018

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Hedgehog signal activation in gastric pit cell and in diffuse-type gastric cancer

21 January 2018

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Cross talk between hedgehog and epithelial-mesenchymal transition pathways in gastric pit cells and in diffuse-type gastric cancers

21 January 2018

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Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas.

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Hedgehog signaling regulates E-cadherin expression for the maintenance of the actin cytoskeleton and tight junctions

21 January 2018

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Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.

21 January 2018

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Cadherin-mediated intercellular adhesion and signaling cascades involving small GTPases

21 January 2018

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Regulation of adherens junctions by Rho GTPases and p120-catenin

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Expression of seven main Rho family members in gastric carcinoma

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.827174

The role of epithelial-mesenchymal transition in cancer pathology

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

21 January 2018

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https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Loss of functional E-cadherin renders cells more resistant to the apoptotic agent taxol in vitro

21 January 2018

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EMT as the ultimate survival mechanism of cancer cells

21 January 2018

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Protein folding and quality control in the endoplasmic reticulum

21 January 2018

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ERAD: the long road to destruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

One step at a time: endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

N-glycan structures: recognition and processing in the ER.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Unglycosylation at Asn-633 made extracellular domain of E-cadherin folded incorrectly and arrested in endoplasmic reticulum, then sequentially degraded by ERAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Protein-misfolding diseases and chaperone-based therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Strategies for the inhibition of protein aggregation in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

E-cadherin destabilization accounts for the pathogenicity of missense mutations in hereditary diffuse gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

The importance of E-cadherin binding partners to evaluate the pathogenicity of E-cadherin missense mutations associated to HDGC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Cadherins in development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Frequent deregulations in the hedgehog signaling network and cross-talks with the epidermal growth factor receptor pathway involved in cancer progression and targeted therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

The prognostic impact of epidermal growth factor receptor in patients with metastatic gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Impact of expression of human epidermal growth factor receptors EGFR and ERBB2 on survival in stage II/III gastric cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Targeted therapies for gastric cancer: current status

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Notch inhibition as a promising new approach to cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Epigenetic regulation of Delta-Like1 controls Notch1 activation in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Monoclonal antibody against the ectodomain of E-cadherin (DECMA-1) suppresses breast carcinogenesis: involvement of the HER/PI3K/Akt/mTOR and IAP pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Somatic Mutations and Deletions of the E-Cadherin Gene Predict Poor Survival of Patients With Gastric Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

Intragenic deletion of CDH1 as the inactivating mechanism of the wild-type allele in an HDGC tumour

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

E-cadherin impairment increases cell survival through Notch-dependent upregulation of Bcl-2

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14728222.2013.827174

10.1517/14728222.2013.827174

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23957294%20AND%20SRC:MED&resulttype=core&format=json

7 March 2020

1 reference