(Q38134308)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

2 references

11 December 2020

19 July 2021

Mechanisms of action of non-steroidal anti-inflammatory drugs (NSAIDs) and mesalazine in the chemoprevention of colorectal cancer (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

2 references

11 December 2020

19 July 2021

1 reference

7 November 2019

non-steroidal anti-inflammatory drug

1 reference

28 October 2020

1 reference

11 December 2020

anti-inflammatory agent

1 reference

19 July 2021

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

author name string

Veronica De Simone

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Francesco Pallone

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Giovanni Monteleone

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

language of work or name

English

0 references

publication date

3 September 2013

10 references

21 March 2019

3 April 2019

22 June 2019

25 June 2019

9 September 2019

7 November 2019

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19 February 2020

28 October 2020

11 December 2020

19 July 2021

International Journal of Molecular Sciences

10 references

21 March 2019

3 April 2019

22 June 2019

25 June 2019

9 September 2019

7 November 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

28 October 2020

11 December 2020

19 July 2021

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

page(s)

17972-17985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 3.0 Unported

19 February 2020

copyright license

9 references

21 March 2019

3 April 2019

22 June 2019

25 June 2019

9 September 2019

7 November 2019

28 October 2020

11 December 2020

on focus list of Wikimedia project

19 July 2021

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling

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6 September 2017

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6 September 2017

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Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs

6 September 2017

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6 September 2017

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Aspirin and low-dose nitric oxide-donating aspirin increase life span in a Lynch syndrome mouse model

6 September 2017

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6 September 2017

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Lysine acetylation targets protein complexes and co-regulates major cellular functions

6 September 2017

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A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2

6 September 2017

1 reference

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Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung

6 September 2017

1 reference

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Aspirin inhibits camptothecin-induced p21CIP1 levels and potentiates apoptosis in human breast cancer cells

6 September 2017

1 reference

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Mesalazine negatively regulates CDC25A protein expression and promotes accumulation of colon cancer cells in S phase

6 September 2017

1 reference

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Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer

6 September 2017

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Aspirin blocks proliferation in colon cells by inducing a G1 arrest and apoptosis through activation of the checkpoint kinase ATM

6 September 2017

1 reference

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5-ASA affects cell cycle progression in colorectal cells by reversibly activating a replication checkpoint

6 September 2017

1 reference

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Aspirin activates the NF-kappaB signalling pathway and induces apoptosis in intestinal neoplasia in two in vivo models of human colorectal cancer

6 September 2017

1 reference

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Introduction to NF-kappaB: players, pathways, perspectives

6 September 2017

1 reference

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Celecoxib for the prevention of sporadic colorectal adenomas

6 September 2017

1 reference

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Review article: mode of action and delivery of 5-aminosalicylic acid - new evidence

6 September 2017

1 reference

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Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A

6 September 2017

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Prostaglandins and cancer

6 September 2017

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5-Aminosalicylate use and colorectal cancer risk in inflammatory bowel disease: a large epidemiological study

6 September 2017

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Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies

6 September 2017

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Mesalazine improves replication fidelity in cultured colorectal cells

6 September 2017

1 reference

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Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator-activated receptor-gamma

6 September 2017

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Aspirin-induced nuclear translocation of NFkappaB and apoptosis in colorectal cancer is independent of p53 status and DNA mismatch repair proficiency

6 September 2017

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Cell-cycle checkpoints and cancer

6 September 2017

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Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells

6 September 2017

1 reference

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Epidermal growth factor receptor: mechanisms of activation and signalling.

6 September 2017

1 reference

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Peroxisome proliferator-activated receptor gamma ligands suppress colon carcinogenesis induced by azoxymethane in mice

6 September 2017

1 reference

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A novel mechanism for aspirin-mediated growth inhibition of human colon cancer cells

6 September 2017

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6 September 2017

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Aspirin potently inhibits oxidative DNA strand breaks: implications for cancer chemoprevention

6 September 2017

1 reference

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The risk of colorectal cancer in ulcerative colitis: a meta-analysis

6 September 2017

1 reference

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Linking colorectal cancer to Wnt signaling

6 September 2017

1 reference

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Genetic disruption of Ptgs-1, as well as Ptgs-2, reduces intestinal tumorigenesis in Min mice

6 September 2017

1 reference

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Inhibition of interleukin-1-stimulated NF-kappaB RelA/p65 phosphorylation by mesalamine is accompanied by decreased transcriptional activity

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytes

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Genetic instabilities in human cancers

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Cyclooxygenase in biology and disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Aspirin suppresses the mutator phenotype associated with hereditary nonpolyposis colorectal cancer by genetic selection

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

6 September 2017

Cyclooxygenases 1 and 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potential

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Checkpoints: controls that ensure the order of cell cycle events

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

A genetic model for colorectal tumorigenesis

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Role of prostaglandins in ulcerative colitis. Enhanced production during active disease and inhibition by sulfasalazine

6 September 2017

1 reference

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Inhibition of prostaglandin biosynthesis by sulphasalazine and its metabolites

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Mesalazine inhibits the beta-catenin signalling pathway acting through the upregulation of mu-protocadherin gene in colo-rectal cancer cells

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

The proapoptotic effects of sulindac, sulindac sulfone and indomethacin are mediated by nucleolar translocation of the RelA(p65) subunit of NF-kappaB.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Cyclooxygenase-2-dependent and -independent inhibition of proliferation of colon cancer cells by 5-aminosalicylic acid.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Sphingosine kinase 1 is up-regulated in colon carcinogenesis

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Silencing of SH-PTP2 defines a crucial role in the inactivation of epidermal growth factor receptor by 5-aminosalicylic acid in colon cancer cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Long-term effect of aspirin on colorectal cancer incidence and mortality: 20-year follow-up of five randomised trials

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Mesalazine reduces mutations in transforming growth factor beta receptor II and activin type II receptor by improvement of replication fidelity in mononucleotide repeats.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Use of nonsteroidal anti-inflammatory drugs and incidence of colorectal cancer: a population-based study

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

5-aminosalicylate is not chemoprophylactic for colorectal cancer in IBD: a population based study.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

5-aminosalicylic acid interferes in the cell cycle of colorectal cancer cells and induces cell death modes

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

PPARgamma is involved in mesalazine-mediated induction of apoptosis and inhibition of cell growth in colon cancer cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

5-aminosalicylic acid inhibits colitis-associated colorectal dysplasias in the mouse model of azoxymethane/dextran sulfate sodium-induced colitis

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

5-Aminosalicylic acid therapy and the risk of colorectal cancer among patients with inflammatory bowel disease

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Peroxisome proliferator-activated receptor expression and activation in normal human colonic epithelial cells and tubular adenomas

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Expression and regulation of nonsteroidal anti-inflammatory drug-activated gene (NAG-1) in human and mouse tissue.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Characteristics of the peroxisome proliferator activated receptor gamma (PPARgamma) ligand induced apoptosis in colon cancer cells

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Ligands for peroxisome proliferator-activated receptors alpha and gamma inhibit chemically induced colitis and formation of aberrant crypt foci in rats

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

The effect of non-steroidal anti-inflammatory drugs on human colorectal cancer cells: evidence of different mechanisms of action.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3794763

Cyclooxygenase 2 Expression in Colorectal Cancer with DNA Mismatch Repair Deficiency

31 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.3390%2FIJMS140917972

Release of sphingosine-1-phosphate from human platelets is dependent on thromboxane formation

21 January 2018

1 reference

12 December 2020

Increased expression of the epidermal growth factor receptor on human colon carcinoma cells

1 reference

12 December 2020

Aminosalicylate therapy in the prevention of dysplasia and colorectal cancer in ulcerative colitis

1 reference

12 December 2020

NSAID activated gene (NAG-1), a modulator of tumorigenesis

1 reference

12 December 2020

Aspirin acetylates multiple cellular proteins in HCT-116 colon cancer cells: Identification of novel targets

1 reference

12 December 2020

Identifiers

DOI

10.3390/IJMS140917972

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

24005861

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24005861%20AND%20SRC:MED&resulttype=core&format=json