(Q38140767)

29 August 2017

title

The role of interleukin-6 in the evolution of ovarian cancer: clinical and prognostic implications--a review (English)

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29 August 2017

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Antonio Macciò

1

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29 August 2017

Clelia Madeddu

series ordinal

2

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29 August 2017

language of work or name

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21 September 2013

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Journal of Molecular Medicine

29 August 2017

published in

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29 August 2017

volume

91

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29 August 2017

issue

12

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29 August 2017

page(s)

1355-1368

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Interleukin-6 and leptin as markers of energy metabolic changes in advanced ovarian cancer patients

29 August 2017

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High serum levels of soluble IL-2 receptor, cytokines, and C reactive protein correlate with impairment of T cell response in patients with advanced epithelial ovarian cancer

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Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer

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A genetically defined model for human ovarian cancer

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Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells

21 January 2018

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Interleukin-6, secreted by human ovarian carcinoma cells, is a potent proangiogenic cytokine

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Serum interleukin-6 levels correlate with disease status in patients with epithelial ovarian cancer

21 January 2018

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Autocrine production of interleukin-6 confers cisplatin and paclitaxel resistance in ovarian cancer cells

21 January 2018

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Quantitative evaluation of oxidative stress, chronic inflammatory indices and leptin in cancer patients: correlation with stage and performance status.

21 January 2018

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Hemoglobin levels correlate with interleukin-6 levels in patients with advanced untreated epithelial ovarian cancer: role of inflammation in cancer-related anemia

21 January 2018

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Leptin as an immunomodulator

21 January 2018

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Serum levels of leptin and proinflammatory cytokines in patients with advanced-stage cancer at different sites

21 January 2018

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Serum values of proinflammatory cytokines are inversely correlated with serum leptin levels in patients with advanced stage cancer at different sites

21 January 2018

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21 January 2018

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21 January 2018

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Interleukin-6 and the acute phase response

21 January 2018

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Paraneoplastic thrombocytosis in ovarian cancer.

21 January 2018

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Efficacy and safety of oral lactoferrin supplementation in combination with rHuEPO-beta for the treatment of anemia in advanced cancer patients undergoing chemotherapy: open-label, randomized controlled study

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers: evaluating the impact on metabolic and inflammatory profiles and quality of life

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Association of IL-6, hypothalamus-pituitary-adrenal axis function, and depression in patients with cancer

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Psychological distress and its correlates in ovarian cancer: a systematic review

21 January 2018

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Prevalence and predictors of psychological distress among women with ovarian cancer.

21 January 2018

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Interleukin-6, cortisol, and depressive symptoms in ovarian cancer patients

21 January 2018

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Mechanisms of cancer cachexia

21 January 2018

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Metabolic pathways in T cell fate and function

21 January 2018

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Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Cancer cachexia demonstrates the energetic impact of gluconeogenesis in human metabolism

21 January 2018

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Interleukin 6 as a key regulator of muscle mass during cachexia

21 January 2018

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21 January 2018

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A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction.

21 January 2018

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21 January 2018

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Dichloroacetate (DCA) as a potential metabolic-targeting therapy for cancer

21 January 2018

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Lipoic acid inhibits cell proliferation of tumor cells in vitro and in vivo

21 January 2018

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The role of cytokines in cancer cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

JAK/STAT3 pathway inhibition blocks skeletal muscle wasting downstream of IL-6 and in experimental cancer cachexia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Aberrations in normal systemic lipid metabolism in ovarian cancer patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Integrative role of neuropeptides and cytokines in cancer anorexia-cachexia syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Interleukin-6 regulates the expression of hypothalamic neuropeptides involved in body weight in a gender-dependent way.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Is pyruvate an endogenous anti-inflammatory molecule?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

A role for the NLRP3 inflammasome in metabolic diseases--did Warburg miss inflammation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Expression of NLRP3 inflammasome and T cell population markers in adipose tissue are associated with insulin resistance and impaired glucose metabolism in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Integration of hormonal and nutrient signals that regulate leptin synthesis and secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Recent advances in understanding leptin signaling and leptin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

The effects of insulin, glucose, and pyruvate on the kinetics of leptin secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Regulation of leptin secretion from white adipocytes by insulin, glycolytic substrates, and amino acids.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Serum protein markers for early detection of ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Correlation between preoperative serum levels of five biomarkers and relationships between these biomarkers and cancer stage in epithelial overian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Immunity and immune suppression in human ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Ovarian cancer creates a suppressive microenvironment to escape immune elimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Immune response in ovarian cancer: how is the immune system involved in prognosis and therapy: potential for treatment utilization

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Tumor-infiltrating cytotoxic T lymphocytes as independent prognostic factor in epithelial ovarian cancer with wilms tumor protein 1 overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Prognostic significance of CD3+ tumor-infiltrating lymphocytes in ovarian carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

IL-6 and leukemia-inhibitory factor are involved in the generation of tumor-associated macrophage: regulation by IFN-γ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Macrophages mediate inflammation-enhanced metastasis of ovarian tumors in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Macrophages induce invasiveness of epithelial cancer cells via NF-kappa B and JNK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Ovarian carcinoma cells inhibit T cell proliferation: suppression of IL-2 receptor beta and gamma expression and their JAK-STAT signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Role of central leptin signaling in the starvation-induced alteration of B-cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Leptin as a Novel Therapeutic Target for Immune Intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

CNS leptin action modulates immune response and survival in sepsis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Management of anemia of inflammation in the elderly

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

The prognostic impact of duration of anemia during chemotherapy in advanced epithelial ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

The blood in systemic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Pro-inflammatory cytokine-mediated anemia: regarding molecular mechanisms of erythropoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Anemia of inflammation: the cytokine-hepcidin link

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Interleukin-6 induces hepcidin expression through STAT3

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Prevalence and management of cancer-related anaemia, iron deficiency and the specific role of i.v. iron

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Cytokine analysis as a tool to understand tumour–host interaction in ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00109-013-1080-7

Regulation of ovarian carcinoma SKOV-3 cell proliferation and secretion of MMPs by autocrine IL-6.

21 January 2018

1 reference

12 December 2020

Partition of energy expenditure between host and tumor

1 reference

12 December 2020

Critical role for mitochondrial oxidative phosphorylation in the activation of tumor suppressors Bax and Bak

1 reference

12 December 2020

IL-6 activates STAT5 in T cells

1 reference

12 December 2020

Erythropoiesis-stimulating agents in the treatment of anaemia in cancer patients: ESMO Clinical Practice Guidelines for use

1 reference

12 December 2020

The stress response of the liver to physical exercise

1 reference

12 December 2020

Interleukin-6 stimulates gluconeogenesis in primary cultures of rat hepatocytes

1 reference

12 December 2020

Higher levels of interleukin-6 in cystic fluids from patients with malignant versus benign ovarian tumors correlate with decreased hemoglobin levels and increased platelet counts

1 reference

12 December 2020

Production of cytokines during interaction of peripheral blood mononuclear cells with autologous ovarian cancer cells or benign ovarian tumour cells

1 reference

12 December 2020

Effects of pro- and antioxidative compounds on renal production of erythropoietin

1 reference

12 December 2020

Interleukin-6 Regulates Human Adipose Tissue Lipid Metabolism and Leptin Productionin Vitro

1 reference

12 December 2020

Ovarian cancer-associated ascites demonstrates altered immune environment: implications for antitumor immunity

1 reference

12 December 2020

Diagnostic markers for early detection of ovarian cancer

1 reference

12 December 2020

IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle

1 reference

12 December 2020

Glucose turnover, gluconeogenesis from glycerol, and estimation of net glucose cycling in cancer patients

1 reference

12 December 2020

Cortisol and inflammatory processes in ovarian cancer patients following primary treatment: relationships with depression, fatigue, and disability

1 reference

12 December 2020

Ethyl pyruvate: a novel treatment for sepsis

1 reference

12 December 2020

Glucose flux in relation to energy expenditure in malnourished patients with and without cancer during periods of fasting and feeding.

1 reference

12 December 2020

Interleukin-6 level in serum and ascites as a prognostic factor in patients with epithelial ovarian cancer

1 reference

12 December 2020

Serum evaluation of interleukin 6 in ovarian cancer patients

1 reference

12 December 2020

Metabolism in peripheral tissues in cancer patients.

1 reference

12 December 2020

Expression of GLUT-1 in epithelial ovarian carcinoma: correlation with tumor cell proliferation, angiogenesis, survival and ability to predict optimal cytoreduction

1 reference

12 December 2020

The relationship of pretreatment serum hemoglobin level to the survival of epithelial ovarian carcinoma patients: a prospective review

1 reference

12 December 2020

Relative expression levels of Th1 and Th2 cytokine mRNA are independent prognostic factors in patients with ovarian cancer.

1 reference

12 December 2020

Malnutrition and cachexia in ovarian cancer patients: pathophysiology and management

1 reference

12 December 2020

Cancer anorexia-cachexia syndrome: are neuropeptides the key?

1 reference

12 December 2020

Psychosocial factors and interleukin-6 among women with advanced ovarian cancer

1 reference

12 December 2020

Proinflammatory and immunosuppressive serum, ascites and cyst fluid cytokines in patients with early and advanced ovarian cancer and benign ovarian tumors

1 reference

12 December 2020

Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma

1 reference

12 December 2020

Profiling of cytokines in human epithelial ovarian cancer ascites.

1 reference

12 December 2020

Tumor-associated lympho-monocytes from neoplastic effusions are immunologically defective in comparison with patient autologous PBMCs but are capable of releasing high amounts of various cytokines

1 reference

12 December 2020

10.1007/S00109-013-1080-7

Identifiers

DOI

1 reference

Dimensions Publication ID

29 August 2017

1026477278

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1 reference