(Q34031638)

30 July 2017

title

Free radicals and antioxidants: updating a personal view (English)

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30 July 2017

1

Barry Halliwell

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30 July 2017

publication date

1 May 2012

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30 July 2017

number of pages

9

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based on heuristic

inferred from page(s)

published in

Nutrition Reviews

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30 July 2017

volume

70

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30 July 2017

issue

5

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30 July 2017

page(s)

257-265

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Oxygen toxicity, oxygen radicals, transition metals and disease

30 July 2017

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21 January 2018

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Aromatic hydroxylation as a potential measure of hydroxyl-radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids

21 January 2018

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Use of aromatic hydroxylation of phenylalanine to measure production of hydroxyl radicals after myocardial ischemia in vivo. Direct evidence for a pathogenetic role of the hydroxyl radical in myocardial stunning.

21 January 2018

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Serendipitous findings while researching oxygen free radicals

21 January 2018

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6-hydroxydopamine increases the hydroxylation and nitration of phenylalanine in vivo: implication of peroxynitrite formation

21 January 2018

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21 January 2018

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Measuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?

21 January 2018

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Measurement of oxidatively generated base damage in cellular DNA.

21 January 2018

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Bioactive eicosanoids: role of prostaglandin F(2α) and F₂-isoprostanes in inflammation and oxidative stress related pathology

21 January 2018

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Free radical-induced damage to DNA: mechanisms and measurement

21 January 2018

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Human biochemistry of the isoprostane pathway

21 January 2018

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Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker in type 2 diabetes

21 January 2018

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Free radical lipid peroxidation: mechanisms and analysis

21 January 2018

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Oxidative stress and human diseases: Origin, link, measurement, mechanisms, and biomarkers.

21 January 2018

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F2-isoprostanes as an indicator and risk factor for coronary heart disease

21 January 2018

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The neurobiology of isoprostanes and Alzheimer's disease

21 January 2018

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Iron as a target of chemoprevention for longevity in humans.

21 January 2018

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Body iron store as a predictor of oxidative DNA damage in healthy men and women

21 January 2018

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The association between low-grade inflammation, iron status and nucleic acid oxidation in the elderly

21 January 2018

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Markers of oxidative damage are not elevated in otherwise healthy individuals with the metabolic syndrome

21 January 2018

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Oxidative stress, obesity, and breast cancer risk: results from the Shanghai Women's Health Study

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Oxidative stress measured by urine F2-isoprostane level is associated with prostate cancer

21 January 2018

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Oxidative damage in ischemic stroke revealed using multiple biomarkers.

21 January 2018

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Association of plasma micronutrient levels and urinary isoprostane with risk of lung cancer: the multiethnic cohort study

21 January 2018

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Plasma protein carbonyls and breast cancer risk in sisters discordant for breast cancer from the New York site of the Breast Cancer Family Registry

21 January 2018

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Urinary markers of nucleic acid oxidation and long-term mortality of newly diagnosed type 2 diabetic patients

21 January 2018

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A role for oxidized phospholipids in atherosclerosis

21 January 2018

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Docosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases

21 January 2018

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Using isoprostanes as biomarkers of oxidative stress: some rarely considered issues

21 January 2018

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Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid

21 January 2018

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Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning?

21 January 2018

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Urate as a physiological substrate for myeloperoxidase: implications for hyperuricemia and inflammation

21 January 2018

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Allantoin in human plasma, serum, and nasal-lining fluids as a biomarker of oxidative stress: avoiding artifacts and establishing real in vivo concentrations.

21 January 2018

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Measurement of allantoin and uric acid in human body fluids. A potential index of free-radical reactions in vivo?

21 January 2018

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Action of biologically-relevant oxidizing species upon uric acid. Identification of uric acid oxidation products

21 January 2018

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Individual responses to chemotherapy-induced oxidative stress

21 January 2018

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A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivo

21 January 2018

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Organelle-targetable fluorescent probes for imaging hydrogen peroxide in living cells via SNAP-Tag protein labeling

21 January 2018

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In vivo mapping of hydrogen peroxide and oxidized glutathione reveals chemical and regional specificity of redox homeostasis.

21 January 2018

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Reaction between peroxynitrite and boronates: EPR spin-trapping, HPLC Analyses, and quantum mechanical study of the free radical pathway

21 January 2018

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Unraveling the biological roles of reactive oxygen species

21 January 2018

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Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix

21 January 2018

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Fluorescent and luminescent probes for measurement of oxidative and nitrosative species in cells and tissues: progress, pitfalls, and prospects

21 January 2018

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Measuring reactive oxygen and nitrogen species with fluorescent probes: challenges and limitations

21 January 2018

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HPLC study of oxidation products of hydroethidine in chemical and biological systems: ramifications in superoxide measurements

21 January 2018

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Biologically relevant metal ion-dependent hydroxyl radical generation. An update

21 January 2018

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Role of free radicals and catalytic metal ions in human disease: an overview

21 January 2018

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Superoxide dependent iron release from ferritin in inflammatory diseases

21 January 2018

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Cellular defenses against superoxide and hydrogen peroxide

21 January 2018

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DNA damage by oxygen-derived species Its mechanism and measurement in mammalian systems

21 January 2018

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Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

21 January 2018

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Nitric oxide and peroxynitrite in health and disease

21 January 2018

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Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions

21 January 2018

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The iron chelator desferrioxamine inhibits atherosclerotic lesion development and decreases lesion iron concentrations in the cholesterol-fed rabbit

21 January 2018

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Iron, atherosclerosis, and neurodegeneration: a key role for cholesterol in promoting iron-dependent oxidative damage?

21 January 2018

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A novel approach to the identification and quantitative elemental analysis of amyloid deposits--insights into the pathology of Alzheimer's disease.

21 January 2018

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The antioxidants of human extracellular fluids

21 January 2018

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ROS signaling: the new wave?

21 January 2018

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A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

21 January 2018

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Redox signals in wound healing

21 January 2018

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Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger H₂O₂, and protein chaperones

21 January 2018

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NADPH oxidase-mediated redox signaling: roles in cellular stress response, stress tolerance, and tissue repair

21 January 2018

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Mechanism of hydrogen peroxide-induced keratinocyte migration in a scratch-wound model

21 January 2018

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Inactivation of peroxiredoxin I by phosphorylation allows localized H(2)O(2) accumulation for cell signaling

21 January 2018

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Chemistry and biology of reactive oxygen species in signaling or stress responses

21 January 2018

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ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis

21 January 2018

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H2O2: a dynamic neuromodulator

21 January 2018

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Signaling functions of reactive oxygen species.

21 January 2018

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Signal transduction by reactive oxygen species

21 January 2018

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Free radicals, proteins and DNA: oxidative damage versus redox regulation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Hydrogen peroxide as a signaling molecule

21 January 2018

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Radical-free biology of oxidative stress

21 January 2018

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Biological redox systems and oxidative stress.

21 January 2018

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Hydrogen peroxide-induced apoptosis: oxidative or reductive stress?

21 January 2018

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Highly reactive oxygen species: detection, formation, and possible functions.

21 January 2018

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Measuring the poise of thiol/disulfide couples in vivo

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Intracellular labile iron.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The role of DNA exonucleases in protecting genome stability and their impact on ageing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Proteasome alterations during adipose differentiation and aging: links to impaired adipocyte differentiation and development of oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The oligomeric conformation of peroxiredoxins links redox state to function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Peroxiredoxin 6: a bifunctional enzyme with glutathione peroxidase and phospholipase A₂ activities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Dietary supplements and mortality rate in older women: the Iowa Women's Health Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Nrf2:INrf2 (Keap1) signaling in oxidative stress

21 January 2018

1 reference

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Nrf2 signaling, a mechanism for cellular stress resistance in long-lived mice

21 January 2018

1 reference

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Hormesis can and does work in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Supplementation with a combination of antioxidants does not affect glycaemic control, oxidative stress or inflammation in type 2 diabetes subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Deceptively simple but simply deceptive--Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects

21 January 2018

1 reference

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Mitochondrial changes in ageing Caenorhabditis elegans--what do we learn from superoxide dismutase knockouts?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Effects of NXY-059 in experimental stroke: an individual animal meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Design, power, and interpretation of studies in the standard murine model of ALS

21 January 2018

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Chronic inflammation and mutagenesis

21 January 2018

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Progress and challenges in translating the biology of atherosclerosis

21 January 2018

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Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

21 January 2018

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Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals

21 January 2018

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Catalase and glutathione peroxidase mimics

21 January 2018

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Calcium and reactive oxygen species in acute pancreatitis: friend or foe?

21 January 2018

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NOX2 complex-derived ROS as immune regulators.

21 January 2018

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Spontaneous and aging-dependent development of arthritis in NADPH oxidase 2 deficiency through altered differentiation of CD11b+ and Th/Treg cells

21 January 2018

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Inflammasome activation in NADPH oxidase defective mononuclear phagocytes from patients with chronic granulomatous disease

21 January 2018

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NADPH oxidase deficiency regulates Th lineage commitment and modulates autoimmunity.

21 January 2018

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Absence of respiratory burst in X-linked chronic granulomatous disease mice leads to abnormalities in both host defense and inflammatory response to Aspergillus fumigatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Oxygen radicals, nitric oxide and human inflammatory joint disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Female X-chromosome mosaicism for NOX2 deficiency presents unique inflammatory phenotype and improves outcome in polymicrobial sepsis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Lactobacillus rhamnosus blocks inflammatory signaling in vivo via reactive oxygen species generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Chronic inflammatory disorders and their redox control: from molecular mechanisms to therapeutic opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Associations between apolipoprotein E genotype and circulating F2-isoprostane levels in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Isoprostane, an "intermediate phenotype" for oxidative stress heritability, risk trait associations, and the influence of chromogranin B polymorphism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Intra-person variation of urinary biomarkers of oxidative stress and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

21 January 2018

The antioxidant paradox

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Antioxidant defense and aging in C. elegans: is the oxidative damage theory of aging wrong?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Taking a "good" look at free radicals in the aging process

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The mitochondrial free radical theory of ageing--where do we stand?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Vitamins C and E: beneficial effects from a mechanistic perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The effect of vitamins C and E on biomarkers of oxidative stress depends on baseline level

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

The stomach as a "bioreactor": when red meat meets red wine

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Limited antioxidant effect after consumption of a single dose of tomato sauce by young males, despite a rise in plasma lycopene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Tomatoes versus lycopene in oxidative stress and carcinogenesis: conclusions from clinical trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Deficiency of Nrf2 Accelerates the Effector Phase of Arthritis and Aggravates Joint Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

Total Antioxidant Capacity of Teas by the Ferric Reducing/Antioxidant Power Assay

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1753-4887.2012.00476.X

10.1111/J.1753-4887.2012.00476.X

21 January 2018

Identifiers

DOI

1 reference

30 July 2017

1 reference