(Q38153196)

29 August 2017

4 references

13 March 2019

6 August 2019

7 October 2019

29 May 2020

Effects of chronic kidney disease and uremia on hepatic drug metabolism and transport (English)

1 reference

chronic renal insufficiency

29 August 2017

4 references

13 March 2019

6 August 2019

7 October 2019

29 May 2020

3 references

13 March 2019

6 August 2019

7 October 2019

pharmaceutical preparation

1 reference

6 August 2019

human digestive system

1 reference

7 October 2019

1 reference

4

Jonathan Himmelfarb

1 reference

29 August 2017

Catherine K Yeung

1

1 reference

29 August 2017

Danny D Shen

series ordinal

2

1 reference

29 August 2017

Kenneth E Thummel

series ordinal

3

1 reference

29 August 2017

language of work or name

English

0 references

publication date

16 October 2013

1 reference

29 August 2017

1 March 2014

4 references

13 March 2019

6 August 2019

7 October 2019

29 May 2020

4 references

29 August 2017

13 March 2019

6 August 2019

7 October 2019

85

1 reference

29 August 2017

3

1 reference

29 August 2017

522-528

1 reference

https://scigraph.springernature.com/pub.10.1038/ki.2013.399

29 August 2017

0 references

cites work

In vitro microvessels for the study of angiogenesis and thrombosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Microengineered physiological biomimicry: organs-on-chips.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Current understanding of drug disposition in kidney disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The evolution of the OATP hepatic uptake transport protein family in DMPK sciences: from obscure liver transporters to key determinants of hepatobiliary clearance.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Inflammation as a risk factor and target for therapy in chronic kidney disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

ESRD impairs nonrenal clearance of fexofenadine but not midazolam

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Altered nonrenal drug clearance in ESRD.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Expression and hepatobiliary transport characteristics of the concentrative and equilibrative nucleoside transporters in sandwich-cultured human hepatocytes.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Cytochrome p450 turnover: regulation of synthesis and degradation, methods for determining rates, and implications for the prediction of drug interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Emerging evidence of the impact of kidney disease on drug metabolism and transport

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Prevalence of chronic kidney disease in the United States

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The human intestinal cytochrome P450 "pie".

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effects of renal failure on drug transport and metabolism

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effects of serum from patients with chronic renal failure on rat hepatic cytochrome P450

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Hepatic drug metabolism and transport in patients with kidney disease.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Drug metabolism in chronic renal failure

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Review on uremic toxins: classification, concentration, and interindividual variability

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The effect of chronic renal failure on hepatic drug metabolism and drug disposition

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Heterotropic cooperativity of cytochrome P450 3A4 and potential drug-drug interactions

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Downregulation of hepatic cytochrome P450 in chronic renal failure.

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Immunoquantitation of FMO1 in human liver, kidney, and intestine

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The Effect of Renal Failure on Hepatic Drug Clearance

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin

6 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor.

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effect of renal failure on drug metabolism by the liver

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Regeneration and maintenance of bile canalicular networks in collagen-sandwiched hepatocytes.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Pharmacokinetics and biliary excretion of bromosulphophthalein, [3H]-ouabain and [3H]-taurocholic acid in rats with glycerol-induced acute renal failure

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Oxidative drug metabolism in liver microsomes from uremic rats.

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effect of hemodialysis on hepatic cytochrome P450 functional expression

23 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effects of uremic serum and uremic toxins on hepatic uptake of digoxin

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

P-glycoprotein expression, localization, and function in sandwich-cultured primary rat and human hepatocytes: relevance to the hepatobiliary disposition of a model opioid peptide.

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Pharmacokinetics and safety of the ketolide telithromycin in patients with renal impairment

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Down-regulation of hepatic cytochrome p450 in chronic renal failure: role of uremic mediators

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Effect of experimental renal failure on the pharmacokinetics of losartan in rats

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

Downregulation of intestinal cytochrome p450 in chronic renal failure

31 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4276411

The effect of chronic renal failure on drug metabolism and transport

31 August 2018

1 reference

12 December 2020

Assessment of the impact of renal impairment on systemic exposure of new molecular entities: evaluation of recent new drug applications

1 reference

12 December 2020

The influence of chronic renal failure on drug metabolism and transport

1 reference

12 December 2020

Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man

1 reference

12 December 2020

Pharmacokinetics and effects of propranolol in terminal uraemic patients and in patients undergoing regular dialysis treatment

1 reference

12 December 2020

Effect of acute renal failure on the clearance and biliary excretion of indocyanine green in perfused rat liver

1 reference

12 December 2020

Clinical pharmacokinetics of nimodipine in normal and impaired renal function

1 reference

12 December 2020

Reduced extraction of I-propranolol by perfused rat liver in the presence of uremic blood

1 reference

12 December 2020

Changes of hepatic microsomal oxidative drug metabolizing enzymes in chronic renal failure (CRF) rats by partial nephrectomy

1 reference

12 December 2020

Evaluation of atypical cytochrome P450 kinetics with two-substrate models: evidence that multiple substrates can simultaneously bind to cytochrome P450 active sites

1 reference

12 December 2020

Inhibitory effect of uremic solutions on protein-DNA-complex formation of the vitamin D receptor and other members of the nuclear receptor superfamily

1 reference

12 December 2020

Nondialysis (home) medication utilization and cost in diabetic and nondiabetic hemodialysis patients

1 reference

12 December 2020

Role of parathyroid hormone in the downregulation of liver cytochrome P450 in chronic renal failure

1 reference

12 December 2020

Regulation of drug-metabolizing enzymes and transporters in infection, inflammation, and cancer

1 reference

12 December 2020

Identifiers

DOI

10.1038/KI.2013.399

1 reference

Dimensions Publication ID

29 August 2017

0 references

1 reference

29 August 2017

1 reference